Bronchogenic Carcinoma in a Scleroderma Patient with Multiple Metastases： One Case Report

作     者：Pradipta Guha Shivesh Shanker Sahai Debasis Sarkar Partha Sardar Anup Singh Bipiab Mandal Bidyut Kumar Das Sanjoy Kumar Chatterjee 

作者机构：Department of General Medicine Medica College Kolkata 700083 West Bengal India. 

出 版 物：《Clinical oncology and cancer researeh》 (CLINICAL ONCOLOGY AND CANCER RESEARCH)

年 卷 期：2010年第7卷第3期

页      面：214-216页

核心收录：

学科分类：090603[农学-临床兽医学] 1007[医学-药学(可授医学、理学学位)] 09[农学] 0906[农学-兽医学] 10[医学] 

主　　题：scleroderma bronchogenic carcinoma metastasis. 

摘      要：Introduction The association between pulmonary interstitial fibrosis and the development of bronchogenic carcinoma in a patient with scleroderma has been reported rarely. It is hypothesized that intense epithelial proliferation that is accompanied by the .brotic process increases the occurrence of carcinomatous changes. We report the case of a pa-tient who presented with 3-year history of Raynaud＇s phenomenon, gradual tightening of the skin which was ignored by the patient and her family members, and a 2-week history of severe respiratory dis-tress with left shoulder and upper back pain followed by the develop-ment of paraparesis. After a series of examinations, the patient was diagnosed with scleroderma and simultaneously with bronchogenic carcinoma and multiple distant metastases.