检索结果-南通市图书馆

Industrial solid wastes to environmental protection materials for removal of gaseous pollutants:A review

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2025年第1期10卷 34-83页

作者： Jiacheng Bao Xin Sun ping Ning Kai Li Jie yang Fei Wang Lei Shi Maohong fan Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming650500China College of Engineering and Physical Sciences and School of Energy ResourcesUniversity of WyomingLaramieWY82071USA College of Engineering Georgia Institute of TechnologyAtlantaGA30332USA

The application of industrial solid wastes as environmentally functional materials for air pollutants control has gained much attention in recent years due to its potential to reduce air pollution in a cost-effective *** this review,we investigate the development of industrialwaste-based functional materials for various gas pollutant removal and consider the relevant reaction mechanism according to different types of industrial solid *** see a recent effort towards achieving high-performance environmental functional materials via chemical or physical modification,in which the active components,pore size,and phase structure can be *** review will discuss the potential of using industrial solid wastes,these modified materials,or synthesized materials from raw waste precursors for the removal of air pollutants,including SO_(2),NO_(x),Hg^(0),H_(2)S,VOCs,and CO_(2).The challenges still need to be addressed to realize this potential and the prospects for future research *** suggestions for future directions include determining the optimal composition of these materials,calculating the real reaction rate and turnover frequency,developing effective treatment methods,and establishing chemical component databases of raw industrial solid waste for catalysts/adsorbent preparation.

关键词： Industrial solid waste Reaction mechanism Modification method Air pollutants

COMPrompter: reconceptualized segment anything model with multiprompt network for camouflaged object detection

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2025年第1期68卷 189-203页

作者： Xiaoqin ZHANG Zhenni YU Li ZHAO Deng-ping fan Guobao XIAO Zhejiang Province Key Laboratory of Intelligent Informatics for Safety and Emergency Wenzhou University Nankai International Advanced Research Institute (SHENZHEN FUTIAN) College of Computer Science Nankai University School of Computer Science and Technology Tongji University

We rethink the segment anything model(SAM) and propose a novel multiprompt network called COMPrompter for camouflaged object detection(COD). SAM has zero-shot generalization ability beyond other models and can provide an ideal framework for COD. Our network aims to enhance the single prompt strategy in SAM to a multiprompt strategy. To achieve this, we propose an edge gradient extraction module, which generates a mask containing gradient information regarding the boundaries of camouflaged objects. This gradient mask is then used as a novel boundary prompt, enhancing the segmentation process. Thereafter, we design a box-boundary mutual guidance module, which fosters more precise and comprehensive feature extraction via mutual guidance between a boundary prompt and a box prompt. This collaboration enhances the model's ability to accurately detect camouflaged objects. Moreover, we employ the discrete wavelet transform to extract high-frequency features from image embeddings. The high-frequency features serve as a supplementary component to the multiprompt ***, our COMPrompter guides the network to achieve enhanced segmentation results, thereby advancing the development of SAM in terms of COD. Experimental results across COD benchmarks demonstrate that COMPrompter achieves a cutting-edge performance, surpassing the current leading model by an average positive metric of 2.2% in COD10K. In the specific application of COD, the experimental results in polyp segmentation show that our model is superior to top-tier methods as well. The code will be made available at https://***/guobaoxiao/COMPrompter.

关键词： segment anything model camouflaged object detection boundary prompt

同方期刊数据库

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年第1期68卷 300-302页

作者： Ze-Min Lin Mai Xiang Wen-Hui Wei Shu-Hui fan Li Chen Jie Wang Xiao-Qian yang Chun-Hao yang Shi-Jun He Jian-ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

基于微流控芯片的秀丽隐杆线虫的研究进展

生物化学与生物物理进展 2011年第10期38卷 877-883页

作者：杨剑萍杨帆李新春于艳艳陈缵光中山大学药学院广州510006

微流控芯片技术作为近年来最前沿的分析技术之一,已经在化学、生物学、医药学等研究领域取得了突破性的进展.微流控芯片具有高通量、微型化和多功能集成化等独特优势,已经成为生物医学研究的新平台之一,被越来越多地应用于秀丽隐杆线虫... 详细信息

微流控芯片技术作为近年来最前沿的分析技术之一,已经在化学、生物学、医药学等研究领域取得了突破性的进展.微流控芯片具有高通量、微型化和多功能集成化等独特优势,已经成为生物医学研究的新平台之一,被越来越多地应用于秀丽隐杆线虫的研究.综述了基于微流控芯片上的秀丽隐杆线虫在生物医学领域中的研究进展,侧重介绍了微流控芯片在线虫的自动化固定、行为学、衰老与发育学、神经学、药物筛选及基因筛选等六大方面所取得的最新进展,并展望了微流控芯片的应用前景.

关键词：微流控芯片秀丽隐杆线虫生物医学

Association between HLA-B*46:01 and cutaneous adverse drug reactions in Han Chinese

在线全文

学校读者我要写书评

暂无评论

Journal of Bio-X Research 2018年第2期1卷 73-78页

作者： Meng-Lin Jiang Lan-Ting Wang Sheng-An Chen fan-ping yang Hao Xiong Yu Su Hui-Zhong Zhu Zheng Qi Sheng-Ying Qin Xiao-Qun Luo Qing-He Xing Children’s Hospital & Institutes of Biomedical Sciences Department of Dermatology Huashan Hospital Fudan University Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders Ministry of Education Shanghai Jiao Tong University Shanghai China

The majority of patients who experience cutaneous adverse drug reactions(cADRs)concurrently receive multiple medications,meaning that the causative drug remains *** explored the association between human leukocyte antigen(HLA)alleles and cADRs,regardless of the allergenic drug,to investigate whether different drug-induced cADRs were associated with the same or similar risk alleles in a Han Chinese *** genotyped a sample of 146 cADR patients and 230 population controls from the same hospital and systematically analyzed the association between HLA Class I genes and *** carrier frequency of HLAB∗46:01 in cADR patients was found to be significantly higher than that in population controls(P=.0021,odds ratio[OR]=2.18,95%confidence interval[CI]:1.33-2.58).Subgroup analysis showed that HLA-B∗46:01 was significantly associated with urticaria and erythema multiforme(P=.0077,OR=2.53,95%CI:1.30-4.91;and P=.0049,OR=2.77,95%CI:1.39-5.50,respectively).Furthermore,a significant association was also detected between HLA-A∗02:01 and erythema multiforme(P=.0038,OR=2.65,95%CI:1.31-5.33).This study is the first to demonstrate that HLA-B∗46:01 is a risk allele for cADRs in a Han Chinese population,indicating that screening for HLA-B∗46:01 prior to the administration of medication may predict the risk of developing cADRs.

关键词： association study cutaneous adverse drug reactions Han Chinese HLA-B∗46:01 risk allele

同方期刊数据库

滋肾活络方联合培哚普利对自发性高血压大鼠左室肥厚的影响

在线全文

学校读者我要写书评

暂无评论

中国老年学杂志 2018年第7期38卷 1675-1678页

作者：杨萍杨帆赵月邵震王梦洁李宇轩吴智春山东中医药大学中医学院山东济南250355

目的探讨滋肾活络方联合培哚普利对自发性高血压大鼠(SHR)血压及左心室肥厚的影响。方法以16周龄SHR为高血压左心室肥厚模型,随机分为模型组、培哚普利组、联合用药组。分别在0、4、8、12 w动态检测尾动脉平均动脉压(MBP)。干预12 w后,... 详细信息

目的探讨滋肾活络方联合培哚普利对自发性高血压大鼠(SHR)血压及左心室肥厚的影响。方法以16周龄SHR为高血压左心室肥厚模型,随机分为模型组、培哚普利组、联合用药组。分别在0、4、8、12 w动态检测尾动脉平均动脉压(MBP)。干预12 w后,测量大鼠左心室质量(LVM),计算左心室质量指数(LVMI);左室心肌苏木素-伊红(HE)染色,观察形态变化;酶联免疫吸附(ELISA)法检测大鼠血清Ⅰ型前胶原羧基端前肽(PICP)及Ⅰ型胶原羧基末端交联肽(ICTP)浓度,计算PICP/ICTP比值。结果联合用药组可有效降低SHR的MBP;减轻SHR的心肌损伤,改善间质重构;降低LVMI及血清PICP浓度、PICP/ICTP比值。结论滋肾活络方联合培哚普利能够有效降低动脉压、减缓左室肥厚。

关键词：滋肾活络方左心室肥厚

静脉注射地佐辛对剖宫产术中不良反应发生的影响

在线全文

学校读者我要写书评

暂无评论

昆明医科大学学报 2016年第7期37卷 62-65页

作者：刘萍杨凡黄红郭学君云南省第三人民医院麻醉科昆明市第一人民医院云南昆明650011

目的观察预先静脉注射地佐辛对剖宫产术中不良反应发生的影响．方法选择2014年5月至2015年4月云南省第三人民医院麻醉科ASAI级择期行剖宫产手术的产妇60例，随机分为A、B2组，每组30例．胎儿取出后，A组产妇静脉注射地佐辛5mg；B组产妇... 详细信息

目的观察预先静脉注射地佐辛对剖宫产术中不良反应发生的影响．方法选择2014年5月至2015年4月云南省第三人民医院麻醉科ASAI级择期行剖宫产手术的产妇60例，随机分为A、B2组，每组30例．胎儿取出后，A组产妇静脉注射地佐辛5mg；B组产妇静脉注射生理盐水1mL．观察2组产妇人手术室后（T0）、麻醉平面固定后（T1）、胎儿取出后5min（T2）、胎儿取出后10min（T3）、胎儿取出15min（T4）胎儿取出30min（T5）及手术结束时（T6）共8个时间点的心率（HR）、收缩压（SBP）和血氧饱和度（SpO2）及术中宫缩痛、寒战和恶心、呕吐不良反应发生情况及产妇对手术的满意度．结果与A组比较，B组T2、T3、T4SBP均明显升高（P〈0．05），B组T2～T6HR均明显增加（P〈0．05）；A组宫缩痛发生率明显低于B组（P〈0．05），A组寒战发生率为13．3％，明显低于B组30％（P〈O．05）．结论剖宫产术中使用地佐辛能有效地预防术中不良反应的发生．

关键词：地佐辛剖宫产不良反应

在线全文

学校读者我要写书评

暂无评论

乙亚胺致急性白血病1例

中国新药与临床杂志 2003年第3期22卷 189-190页

作者：卢庆忠栗竹琴檀济平杨帆平山县医院内科河北平山050400

乙亚胺作为一种抗代谢药,临床上常用于银屑病的治疗.但在治疗过程中我们发现1例病人引起急性粒-单核细胞白血病,作者未见国内文献报道,现报告如下.

关键词：白血病粒-单核细胞急性银屑病乙亚胺药物不良反应

The regulation of protein translation and its implications for cancer

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2021年第3期6卷 734-742页

作者： ping Song fan yang Hongchuan Jin Xian Wang Department of Medical Oncology Cancer Institute of Zhejiang UniversitySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiangChina Department of Hepatobiliary and Pancreatic Surgery First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina Key Lab of Biotherapy in Zhejiang Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiangChina

In addition to the deregulation of gene transcriptions and post-translational protein modifications,the aberrant translation from,mRNAs to proteins plays an important role in the pathogenesis of various *** mRNA translation are expected to become potential approaches for anticancer *** translation is affected by many factors including translation initiation factors and RNA-binding ***,modifications of mRNAs mainly N6-methyladenine(m6A)modification and noncoding RNAs,such as microRNAs and long noncoding RNAs are *** this review,we generally summarized the recent advances on the regulation of protein translation by the interplay between mRNA modifications and *** doing so,we hope this review could offer some hints for the development of novel approaches in precision therapy of human cancers.

关键词： translation such summarized