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Frontiers of Agricultural Science and Engineering 2022年第2期9卷 214-237页

作者： Timothy S.GEORGE Cathy HAWES Tracy A.VALENTINE Alison J.KARLEY pietro p.m.iannetta Robin W.BROOKER Ecological Sciences Department The James Hutton InstituteInvergowrieDundeeDD25DAUK

To achieve the triple challenge of food security,reversing biodiversity declines plus mitigating and adapting to climate change,there is a drive to embed ecological principles into agricultural,value-chain practices and *** diversifying cropping systems at several scales there is potential to decrease reliance on inputs,provide resilience to abiotic and biotic stress,enhance plant,microbe and animal biodiversity,and mitigate against climate *** this review we highlight the research performed in Scotland over the past 5 years into the impact of the use of ecological principles in agriculture on sustainability,resilience and provision of ecosystem *** demonstrate that diversification of the system can enhance ecosystem *** and plant management interventions,including nature-based solutions,can also enhance soil quality and utilization of legacy ***,this is facilitated by greater reliance on soil biological processes and trophic *** highlight the example of intercropping with legumes to deliver sustainability through ecological principles and use legumes as an exemplar of the *** conclude that there are many effective interventions that can be made to deliver resilient,sustainable,and diverse agroecosystems for crop and food production,and these may be applicable in any agroecosystem.

关键词： diversification ecological principles legumes plant management soil management soil ecosystem services

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作物生产系统中的植物多样性与生态集约化

Journal of plant Ecology 2023年第6期16卷 16-30页

作者： Rob W.Brooker Cathy Hawes pietro p.m.iannetta Alison J.Karley Delphine Renard Ecological Sciences The James Hutton InstituteInvergowrieDundee DD25DAUK CEFE Univ MontpellierCNRSEPHEIRDMontpellierFrance

生态集约化是指通过强化生态系统服务实现以补充或替代人为输入来维持或增加产量的目标。生态集约化具有提高农业环境可持续性的潜力,例如通过降低对环境不利的管理活动而又维持产量。生态集约化基于生态过程,而这些过程受到生物多样性... 详细信息

生态集约化是指通过强化生态系统服务实现以补充或替代人为输入来维持或增加产量的目标。生态集约化具有提高农业环境可持续性的潜力,例如通过降低对环境不利的管理活动而又维持产量。生态集约化基于生态过程,而这些过程受到生物多样性的影响。本文综述了多空间尺度下生物多样性,特别是维管植物多样性如何调节与生态集约化相关的生态过程。在植物个体基因型水平上,功能性状的互补性直接影响生产力;在田块内种群水平上,作物混合类型具有抗灾能力,以减少病虫害的发生和传播的风险;尺度转换到田间水平,非作物植物类型(如杂草)的多样性为田块内的功能过程提供了必要的资源,包括地下(碳输入、分解)和地上(传粉媒介和天敌的资源连续性)。在景观尺度上,半自然和管理的植被嵌合体通过减轻洪涝和干旱风险、改善气候和调节虫害种群,为抵御极端事件提供缓冲。总体而言,上述强调了尺度异质性在农田维持生态系统功能的重要性。本综述的主要研究挑战包括:1)将植物功能多样性(从性状到栖息地尺度)更好地整合到种植系统设计中;2)量化植物多样性相对于其他管理选项对有效生态集约化的可能互动贡献,3)并通过有针对性的管理优化生物多样性的系统功能优势,以实现具有弹性、高效和高产的农业生态系统。

关键词：生态集约化植物多样性可持续农业间作作物混作生态系统功能生态系统服务

A Chopper Negative-R Delta-Sigma ADC for Audio mEmS Sensors

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Computer modeling in Engineering & Sciences 2022年第2期130卷 607-631页

作者： Jamel Nebhen pietro m.Ferreira College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAlkharj11942Saudi Arabia Universit´e paris-Saclay Centrale SupelecCNRSLaboratory de G´enie Electrique et Electronique de ParisGif-sur-Yvette91192France Sorbonne Universite CNRSLab.de Genie Electrique et Electronique de ParisParis75252France

This paper presents a proposed low-noise and high-sensitivity Internet of Thing(IoT)system based on an m&NEmS *** IoT device consists of an m&NEmS resistive accelerometer associated with an electronic readout circuit,which is a silicon nanowire and a Continuous-Time(CT)△∑*** first integrator of the△∑ADC is based on a positive feedback DC-gain enhancement two-stage amplifier due to its high linearity and low-noise *** mitigate both the offset and 1/f noise,a suggested delay-time chopper negative-R stabilization technique is applied around the first integrator.A 65-nm CmOS process implements the CT△∑*** supply voltage of the CmOS circuit is 1.2-V while 0.96-mW is the power consumption and 0.1-mm^(2) is the silicon *** m&NEmS microphone and△∑ADC complete circuit are fabricated and *** a working frequency bandwidth of 20-kHz,the measurement results of the proposed IoT system reach a signal to noise ratio(SNR)of ***,it has a measured dynamic range(DR)of 108-dB and a measured signal to noise and distortion ratio(SNDR)of 101.3-dB.

关键词： m&NEmS sensor △∑ ADC chopper negative-R IoT 1/f noise SNR

Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5141-5142页

作者： pietro Di Fazio Department of Visceral Thoracic and Vascular SurgeryPhilipps University of MarburgBaldingerstrasse35043MarburgGermany

Two recent studies published in Nature focused on the clinical efficacy of the menin inhibitor revumenib(SNDX-5613)in KmT2A(histone-lysine N-methyltransferase 2A)-rearranged or Npm1(Nucleophosmin1)-mutant acute myeloid leukemia.1,2 These studies indicate that menin inhibition and its acquired resistance to long-term exposure to revuminib are key points for future treatment,emphasizing the role of menin as a challenging and promising target for the current treatment of leukemia.

关键词： acute clinical therapeutic

Comparison Between Deep Learning models and Traditional machine Learning Approaches for Facial Expression Recognition in Ageing Adults

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Journal of Computer Science & Technology 2020年第5期35卷 1127-1146页

作者： Andrea Caroppo Alessandro Leone pietro Siciliano Institute for microelectronics and microsystems National Research Council of ItalyLecce 73100Italy

Facial expression recognition is one'of the most active areas of research in computer vision since one of the non-verbal communication methods by which one understands the lnood/mental state of a person is the expression of ***,it has been used in various fields such as human-robot interaction,security,computer graphics animation,and ambient ***,it remains a challenging task since existing approaches lack generalizability and almost all studies ignore the effects of facial attributes,such as *** expression recognition even though the research indicates that facial expression inanifestation varies with ***,a lot of progress has been made in this topic and great improvements in classification task were achieved with the emergence of deep learning *** approaches have sliown how hierarchies of features can be directly learned from original data,thus avoiding classical hand designed feature extraction methods that generally rely on manual operations witli labelled ***,research papers systematically exploring tlu4 performance of existing deep architectures for the task of classifying expression of ageing adults are absent in the *** the present work a tentative to try this gap is done considering the performance of three recent deep convolutiorial neural networks models(VGG-16,AlexNet and GoogLeNet/Inception V1)and evaluating it on four different benchmark datcisets(FACES,Lifespan,CIFE,and FER2013)which also contain facial expressions performed by elderly *** the baseline,and with the aim of making a comparison,two traditional inacliine learning approaches based on handcrafted features extraction process are evaluated on the same *** out an exhaustive and rigorous experimentation focused on the concept of "transfer learning",which consists of replacing the output level of the deep architectures considered with new output levels appropriate to the number of classes(facial expressions),

关键词： computer vision deep learning facial expression machine learning ageing adult

messages from powdery mildew DNA:How the Interplay with a Host moulds pathogen Genomes

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Journal of Integrative Agriculture 2014年第2期13卷 233-236页

作者： pietro D Spanu Department of Life Sciences Imperial College LondonLondon SW7 2AZUnited Kingdom

The genomes of the barley, Arabidopsis and pea powdery mildew are significantly larger than those of related fungi. This is due to an extraordinary expansion of retro-trasposons that are evident as repetitive elements in the sequence. The protein coding genes are fewer than expected due to an overall reduction in the size of gene families, a reduction in the number of paralogs and because of the loss of certain metabolic pathways. many of these changes have also been observed in the genomes of other taxonomically unrelated obligate biotrophic pathogens. The only group of genes that bucks the trend of gene loss, are those encoding small secreted proteins that bear the hall marks of effectors.

关键词： barley powdery mildew genome effectors

Unsteady Inflow Effects on the Wake Shed from a High-Lift LpT Blade Subjected to Boundary Layer Laminar Separation

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Journal of Thermal Science 2012年第2期21卷 97-108页

作者： Francesca Satta marina Ubaldi pietro Zunino Università degli Studi di Genova

An experimental investigation on the near and far wake of a cascade of high-lift low-pressure turbine blades subjected to boundary layer separation over the suction side surface has been carried out, under steady and unsteady inflows. Two Reynolds number conditions, representative of take-off/landing and cruise operating conditions of the real engine, have been tested. The effect of upstream wake-boundary layer interaction on the wake shed from the profile has been investigated in a three-blade large-scale linear turbine cascade. The comparison between the wakes shed under steady and unsteady inflows has been performed through the analysis of mean velocity and Reynolds stress components measured at midspan of the central blade by means of a two-component crossed miniature hot-wire probe. The wake development has been analyzed in the region between 2% and 100% of the blade chord from the central blade trailing edge, aligned with the blade exit direction. Wake integral parameters, half-width and maximum velocity defects have been evaluated from the mean velocity distributions to quantify the modifications induced on the vane wake by the upstream wake. moreover the thicknesses of the two wake shear layers have been considered separately in order to identify the effects of Reynolds number and incoming flow on the wake shape. The self-preserving state of the wake has been looked at, taking into account the different thicknesses of the two shear layers. The evaluation of the power density spectra of the velocity fluctuations allowed the study of the wake unsteady behavior, and the detection of the effects induced by the different operating conditions on the trailing edge vortex shedding.

关键词： Wake-wake unsteady interaction high-lift blade profiles low-pressure turbine blade wake.

Adult neurogenesis and regeneration in zebrafish brain: are the neurotrophins involved in?

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Neural Regeneration Research 2019年第12期14卷 2067-2068页

作者： pietro Cacialli Carla Lucini Department of Veterinary medicine University of Naples Federico Ⅱ

Neurotrophins (NTs) are implicated in the maintenance and survival of the peripheral and central nervous systems and mediate several forms of synaptic plasticity. members of the family include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), NT3, and NT4. NTs were first identified as survival factors for developing neurons, but are pleiotropic molecules that can exert a variety of functions, including the regulation of neuronal differentiation, axonal and dendritic growth, and synaptic plasticity (Bothwell, 2014). NTs interact with two distinct types of receptors: the common p75 neurotrophin receptor, which belongs to the tumor necrosis factor receptor superfamily of death receptors and the Trk receptor tyrosine kinase family.

关键词： Adult neurogenesis regeneration neurotrophins

Assessing spatial variability and erosion susceptibility of soils in hilly agricultural areas in Southern Italy

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International Soil and Water Conservation Research 2020年第4期8卷 354-362页

作者： Carmen maria Rosskopf Erika Di Iorio Luana Circelli Claudio Colombo pietro p.C.Aucelli University of molise Department of Biosciences and Territoryc.da Fonte Lappone86090PescheISItaly University of molise Department of AgriculturalEnvironmental and Food SciencesVia F.De Sanctis186100CampobassoCBItaly University of Napoli"parthenope" Department of Environmental SciencesCentro Direzionale Isola C/480143NapoliItaly

Soil erosion is one of the main environmental problems in the mediterranean *** problem is becoming even more important especially in Italy,in the Apennines,where severe erosive processes occur due to the action of concentrated running *** erodibility(K-Factor)of a soil,estimated using the Revised Universal Soil Loss Equation(RUSLE),is a measure of its susceptibility to erosion and depends on several soil properties such as organic matter,texture and permeability and *** assess the spatial variability of soil properties and soil erodibility in hilly agricultural areas and to investigate the relationships between soil features and landscape morphodynamics,a detailed study in molise region(southern Italy),in a small drainange basin located along its hilly Adriatic flank,was carried *** this catchment,63 topsoil samples(A horizons)were collected and 10 soil profiles,forming a catena crossing 3 land units,were *** calculated K-Factors ranges between 0.012 and 0.048 t ha h ha-1 mJ-1 mm-1 indicating a complex spatial distribution,due to the several local pedological and geomorphological factors affecting soil *** results give clear evidence about the relationships among soil characteristics,soil erodibility and landscape morpho-dynamics(land units).Comparing the soil loss rates estimated for the study area with those reported in literature,a good correspondence can be observed only for the more stable land unit,not characterized by intense erosive *** proposed methodology is suitable to highlight areas characterized by similar morphodynamics features,and comparable soil erodibility,for a more effective spatialization of K factor.

关键词： Hillslope morphodynamics RUSLE equation K factor mediterranean region Soil catena Land units

Therapeutic potential of curcumin in digestive diseases

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World Journal of Gastroenterology 2013年第48期19卷 9256-9270页

作者： pietro Dulbecco Vincenzo Savarino Department of Internal medicine and medical Specialties University of Genoa 16132 Genoa Italy

Curcumin is a low-molecular-weight hydrophobic polyphenol that is extracted from turmeric,which possesses a wide range of biological properties including anti-inflammatory,anti-oxidant,anti-proliferative and anti-microbial *** its diverse targets and substantial safety,clinical applications of this molecule for digestive disorders have been largely limited to case series or small clinical *** poor bioavailability of curcumin is likely the major hurdle for its more widespread use in ***,complexation of curcumin into phytosomes has recently helped to bypass this problem,as it has been demonstrated that this new lecithin formulation enables increased absorption to a level 29-fold higher than that of traditional curcuminoid *** allows us to achieve much greater tissue substance delivery using significantly lower doses of curcumin than have been used in past clinical *** curcumin has already been shown to provide good therapeutic results in some small studies of both inflammatory and neoplastic bowel disorders,it is reasonable to anticipate an even greater efficacy with the advent of this new technology,which remarkably improves its *** features are very promising and may represent a novel and effective therapeutic approach to both functional and organic digestive diseases.

关键词： Curcumin Curcumin-phythosome Curcumin bioavailability Digestive disorders