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Comparative analysis of the antioxidant capacity and lipid and protein oxidation of soy and oats beverages

Food Production, Processing and Nutrition 2021年第1期3卷 1-10页

作者： Laura Moretto Federica Tonolo Alessandra Folda Valeria Scalcon Alberto Bindoli Marco Bellamio Emiliano Felle Maria pia Rigobello Department of Biomedical Sciences University of Padovavia Ugo Bassi 58/b35131 PadovaItaly Institute of Neuroscience(CNR) viale G.Colombo 335131 PadovaItaly Centrale del Latte di Vicenza s.p.a via A.Faedo 60.36100 VicenzaItaly

Soy(Glycine max)and oats(Avena sativa)are plant sources used in milk-alternative ***,protein and lipid constituents of these food matrices can undergo alterations during the *** this work,a commercial formulation of soy and oat-based beverages were comparatively *** the 12 months of shelf life and two following months,their phenolic content,antioxidant capacity,lipid peroxidation,protein carbonyl formation and protein breakdown were *** phenolic content and antioxidant capacity of soy and oat-based beverages were maintained during the entire period of 14 *** beverages did not show any increase in spontaneous lipid peroxidation beyond the basal level,however,due to the different content of unsaturated fats,when lipid peroxidation was stimulated,soy exhibited a major peroxidizability with respect to oat *** alteration of proteins,estimated as carbonyl group formation,presented no increase with respect to the basal levels both in soy and oat beverages for all 14 ***,soy proteins showed a gradual increase of proteolytic activity up until half of the shelf life,while oat did not show significant changes in protein *** conclusion,both soy and oat beverages resulted oxidatively stable throughout their *** suggest that phytochemicals might guarantee the oxidative stability of the product,possibly in combination with antioxidant bioactive peptides,which already have well-known benefits on human health.

关键词： Soy Oats Plant-based beverages Oxidation Antioxidants Shelf life

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Thrinchostoma Saussure, little known bee genus from China, with description of a new species (Hymenoptera： Halictidae)

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Zoological Systematics 2016年第2期41卷 207-215页

作者： Zeqing Niu Feng Yuan pia Oremek Feng Liu Chaodong Zhu Key Laboratory of Zoological Systematics and Evolution Institute of Zoology Chinese Academy of Sciences 1 Beichen West Road Chaoyang District Beijing 100101 China Agroecology in the Tropics and Subtropics (380b) University of Hohenheim Stuttgart 70593 Germany Naban River Watershed National Nature Reserve Jinghong Xishuangbanna 666100 China

The bee genus Thrinchostoma Saussure, 1890 is reported from China with a new species and a new record species, T. （Thrinchostoma） yunnanense Niu ＆ Zhu, sp. nov. and T（T.） sladeni Cockerell, 1913. An illustrated key to the two Chinese species of the subgenus Thrinchostoma （T.） is provided. The type specimens are deposited in Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

关键词： Apoidea Apiformes taxonomy Xishuangbanna.

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Endometritis associated with Enterococcus casseliflavus in a mare:A case report

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Asian Pacific Journal of Tropical Biomedicine 2017年第8期7卷 760-762页

作者： Francesca Paola Nocera Chiara Papulino Chiara Del Prete Veronica Palumbo Maria pia Pasolini Luisa De Martino Department of Veterinary Medicine and Animal Production University of Naples'FedericoⅡ'NaplesItaly

Infectious endometritis is one of the main causes of subfertility/infertility in the mare. In this report, we present the first case of endometritis in mare associated with a strain of Enterococcus casseliflavus, an unusual gram-positive bacterium which can also be a zoonotic agent. Furthermore, the isolated strain showed a worrying multidrug-resistant profile. The accurate finding of a successful antimicrobial treatment and consequently,the pregnancy diagnosis indicate the importance to isolate, identify and define the antibiotic resistance profile of bacteria associated with endometritis.

关键词： Endometritis Enterococcus casseliflavus Mares Subfertility

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STAZIONE DELL'ANTICA ET(?) DEL BRONZO AD OSTIANO(CREMONA),LOCALIT(?)SAN SALVATORE Nota preliminare sulla campagna dell'agosto 1980

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Natural Disaster Reduction in China 1980年第1期 242-265页

作者： GABRIELLA E.pia

The Early Bronze Age settlement at Ostiano *** is located on afluvial terrace at the confluence of the rivers Oglio and *** site produced evidenceof an archaeological layer,pits and post *** prehistoric structures yielded pottery and flint artefacts attributable to a local aspectof the Polada Culture,while no Middle Bronze Age potsherds or handles,arise ad ascia forinstance,have been found so *** chronological sequence of the pits seems to be asfollows:5,3,Ⅳ,Ⅰ,Ⅱ and Ⅲ.Pits 1 and 4 might be contemporary to each *** produced a small amount of *** results will be available when thestudy of all the structures will be *** faunal remains show that a well balanced economy was practised at the ***,sheep/goat and pig,in descending order,were the animals killed for meat.A scarcehunting activity is attested by red deer and roe deer *** data slightly differfrom those from the other Po Plain EBA sites from where there is evidence of a prevailingpig *** were also cultivated as revealed by the presence of burnt seeds andsickle blades made from *** at Ostiano *** also collected wild plants.A few pieces of daub indicate that the buts had wooden and clay *** greatvariety of vessels produced by the pits might suggest that pottery was locally *** contrary the flint artefacts are very rare,being composed of 28 tools *** bronzeimplements are extremely *** actually do not know whether this is due to thedistance of the site from the ore veins or to the various activities practised at differentsites complementary to each *** EBA settlement closed to *** is Cella Dati which also produced a few MBAsherds.

关键词： Pi DEL BRONZO AD OSTIANO LOCALIT SAN SALVATORE Nota preliminare sulla campagna dell’agosto 1980 STAZIONE DELL’ANTICA ET CREMONA La

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Breast cancer stem cells: The role of sex steroid receptors

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World Journal of Stem Cells 2019年第9期11卷 594-603页

作者： pia Giovannelli Marzia Di Donato Giovanni Galasso Erika Di Zazzo Nicola Medici Antonio Bilancio Antimo Migliaccio Gabriella Castoria Department of Precision Medicine University of Campania "L.Vanvitelli"

Breast cancer(BC)is the most common cancer among women,and current available therapies often have high success ***,BC might acquire drug resistance and sometimes *** knowledge about the most aggressive forms of BC points to the role of specific cells with stem properties located within BC,the so-called“BC stem cells”(BCSCs).The role of BCSCs in cancer formation,growth,invasiveness,therapy resistance and tumor recurrence is becoming increasingly *** growth and metastatic properties of BCSCs are regulated by different pathways,which are only partially *** steroid receptors(SSRs),which are involved in BC etiology and progression,promote BCSC proliferation,dedifferentiation and ***,in the literature,there is incomplete information about their ***,there are contrasting conclusions about the expression and role of the classical BC hormonal biomarkers,such as estrogen receptor alpha(ERα),together with scant,albeit promising information concerning ER beta(ERβ)and androgen receptor(AR)properties that control different transduction pathways in *** this review,we will discuss the role that SRs expressed in BCSCs play to BC progression and recurrence and how these findings have opened new therapeutic possibilities.

关键词： Breast cancer Steroids Sex steroid receptors Cancer stem cells Therapeutic implications

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Combined therapy with bevacizumab and photodynamic therapy for myopic choroidal neovascularization: A oneyear follow-up controlled study

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 335-339页

作者： Sandro Saviano Rita Piermarocchi pia E.Leon Alessandro Mangogna Andrea Zanei Fabiano Cavarzeran Sc Daniele Tognetto University Eye Clinic University of TriesteOspedale Maggiore Trieste 34129 Italy Eye Clinic of Padova University of Padova

AIMTo evaluate the efficacy and safety of a combined treatment for myopic choroidal neovascularization (CNV) using photodynamic therapy (PDT) and intravitreal bevacizumab and to compare it with intravitreal bevacizuma... 详细信息

关键词： bevacizumab combined therapy myopia neovascularization photodynamic therapy

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通过测量氡的放射性来监测大气稳定度的新方法

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中国环境科学 2013年第4期33卷 594-598页

作者：王芬娟张华 Maria pia Ancora 邓晓东国家气候中心北京100081 清华大学环境学院北京100084 兰州市环境监测站甘肃兰州730000

介绍了一种通过测量氡和其短周期衰变产物的自然放射性来监测大气稳定度的新方法,该指标反映了低层大气边界层的混合特性,能够反映一次污染物的稀释扩散特征.将这种方法测量的大气稳定度与通用的帕斯奎尔分类法计算的稳定度进行对比,该... 详细信息

介绍了一种通过测量氡和其短周期衰变产物的自然放射性来监测大气稳定度的新方法,该指标反映了低层大气边界层的混合特性,能够反映一次污染物的稀释扩散特征.将这种方法测量的大气稳定度与通用的帕斯奎尔分类法计算的稳定度进行对比,该方法不仅能准确反映大气稳定度长期趋势和昼夜变化,还能反映大气稳定度的瞬时变化,是解析环境污染数据,特别是一次污染物的有利工具.2007年在兰州市的观测结果显示PM10与大气稳定度的观测数值有很好的一致性趋势,表明低层大气的混合特性是决定一次污染物浓度的关键因素.

关键词：大气稳定度氡放射性一次污染物

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IFN-γ upregulates membranous and soluble PD-L1 in mesothelioma cells: potential implications for the clinical response to PD-1/PD-L1 blockade

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Cellular & Molecular Immunology 2020年第4期17卷 410-411页

作者： Maria pia Pistillo Roberta Carosio Barbara Banelli Anna Morabito Luca Mastracci Paola Ferro Serena Varesano Roberta Venè Alessandro Poggi Silvio Roncella Tumor Epigenetics Unit IRCCS Ospedale Policlinico San Martino16132 GenoaItaly Department of Surgical Sciences and Integrated Diagnostics(DISC) University of Genoa16132 GenoaItaly Anatomic Pathology IRCCS Ospedale Policlinico San Martino16132 GenoaItaly Histopathology and Cytopathology Division Azienda Sanitaria Locale 519121 La SpeziaItaly Molecular Oncology and Angiogenesis Unit IRCCS Ospedale Policlinico San Martino16132 GenoaItaly AIL Associazione italiana contro le leucemielinfomi e mieloma19121 La SpeziaItaly

Programmed death-ligand-1(PD-L1)plays a crucial role in the suppression of the antitumor immune response upon interaction with programmed cell death protein-1(PD-1)on cytotoxic T ***-L1 is constitutively expressed on antigen-presenting cells or tumor ***,PD-L1 has been detected by immunohistochemistry in a variety of tumors,including malignant pleural mesothelioma(MPM),in which it has emerged as a predictive biomarker for PD-1/PD-L1 immune checkpoint blockers(ICBs).1,2 PD-L1 expression on tumor cells can be upregulated by several factors including the interferon gamma(IFN-γ)cytokine produced by tumor-infiltrating lymphocytes(TILs).3 In MPM cells,it has been reported that IFN-γupregulates PD-L1 mRNA expression due to the activation of the interferon regulatory factor 1(IRF1)transcription factor,4 but no data have been shown regarding cell surface PD-L1 that is functionally relevant for its contact with PD-1-positive cells.

关键词： interferon death pleural

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Ehealth monitoring in irritable bowel syndrome patients treated with low fermentable oligo-, di-, mono-saccharides and polyols diet

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World Journal of Gastroenterology 2014年第21期20卷 6680-6684页

作者： Natalia Pedersen Zsuzsanna Vegh Johan Burisch Lisbeth Jensen Dorit Vedel Ankersen Maria Felding Nynne Nyboe Andersen pia Munkholm Digestive Disease Centre Medical SectionHerlev University HospitalCopenhagen 2730Denmark Department of Medicine Veszprém Megyei Csolnoky Ferenc KórházVeszprém 8200Hungary Clinical Nutrition Faculty of ScienceUniversity of Copenhagen 1870Denmark Department of Epidemiology Research Statens Serum InstitutCopenhagen 2300Denmark

In the present study we report on changes in irritable bowel syndrome-severity scoring system (IBS-SSS) and irritable bowel syndrome-quality of life (IBS-QoL) in 19 IBS patients, aged 18 to 74 years (F/M: 14/5), during 12 wk registering their symptoms on the web-application (***). During a control period of the first 6-wk patients were asked to register their IBS-SSS and IBS-QoL on the web-application weekly without receiving any intervention. Thereafter, low fermentable oligo-, di-, mono-saccharides and polyols (FODMAP) diet (LFD) was introduced for the next 6 wk while continuing the registration. Though a small sample size a significant improvement in disease activity (IBS-SSS) was observed during both the control period, median: 278 (range: 122-377), P = 0.02, and subsequently during the LFD period, median: 151 (range: 29-334), P < 0.01. The IBS-QoL solely changed significantly during the LFD period, median: 67 (37-120), P < 0.01. The significant reduction in disease activity during the control period shows a positive effect of the web-application on IBS symptoms when presented as a “traffic light”. However adding the diet reduced IBS-SSS to < 150, inactive to mild symptoms. In the future results from larger scale trials are awaited.

关键词： Irritable bowel syndrome Low fermentable oligo- di- mono-saccharides and polyols diet Self-management Disease-specific quality of life Disease activity

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Spontaneous or secondary to intravitreal injections of anti-angiogenic agents retinal pigment epithelial tears in age-related macular degeneration

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International Journal of Ophthalmology(English edition) 2014年第4期7卷 681-685页

作者： pia E.Leon Sandro Saviano Andrea Zanei Marco R.Pastore Elvira Guaglione Alessandro Mangogna Daniele Tognetto University Eye Clinic of Trieste Ospedale Maggiore

·AIM:Toevaluatethevisualfunctionevolutionofretinal pigment epithelial(RPE) tears in patients with age-related macular degeneration(AMD) according to type of occurrence [spontaneous or secondary to anti-vascular endothelial growth factor(anti-VEGF) injection] and the topographic location of the tear after a two-year followup period.·METHODS: A total of 15 eyes of 14 patients with RPE tears in exudative AMD were analyzed retrospectively at the University Eye Clinic of Trieste. Inclusion criteria were: patient age of 50 or older with AMD and RPE tears both spontaneous occurring or post anti-VEGF treatment. Screening included: careful medical history,complete ophthalmological examination, fluorescein angiography(FA), indocyanine green angiography(ICG),autofluorescence and infrared imaging and optical coherence tomography(OCT). Patients were evaluated every month for visual acuity(VA), fundus examination and OCT. Other data reported were: presence of PED,number of injections before the tear, location of the lesion.·RESULTS:Meanfollow-up was24wk(SD±4wk). Atotal of 15 eyes were studied for RPE tear. In 6 cases(40%),the RPE tears occurred within two years of anti-VEGF injections the others occurred spontaneously. In 13cases(86.6%), the RPE tear was associated with pigment epithelial detachment(PED). In 7 cases(46.6%), the RPE tear occurred in the central area of the retina and involved the fovea. Two lesions were found in the parafoveal region, six in the extra-macular area. In all cases visual acuity decreased at the end of the follow-up period(P <0.01) independently of the type or the topographical location of the lesion.·CONCLUSION: RPE tear occurs in exudative AMD as a spontaneous complication or in relation to anti-VEGF injections. Visual acuity decreased significantly and gradually in the follow-up period in all cases. No correlation was found between visual loss and the type of onset or the topographic location of the tears.

关键词： retinal pigment epithelial age-related macular degeneration tears visual acuity anti-vascular endothelial growth factor treatment

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