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Functionally graded structure of a nitride-strengthened Mg_(2)Si-based hybrid composite

Journal of Magnesium and Alloys 2024年第3期12卷 1239-1256页

作者： je.ngho Yang Woongbeom Heogh Hogi Ju Sukhyun Kang Tae-Sik Jang Hyun-Do Jung Mohammad Jahazi Seung Chul Han Seong je Park Hyoung Seop Kim Susmita Bose Amit Bandyopadhyay Martin Byung-Guk Jun Young Won Kim Dae-kyeom Kim Rigoberto CAdvincula Clodualdo Aranas Jr Sang Hoon Kim School of Mechanical Engineering Pusan National UniversityBusan 46241Republic of Korea Department of Mechanical Design Engineering Hanyang UniversitySeoul 04763Republic of Korea Process Research 3 Team LG Display Co.Ltd.PajuGyeonggi-do 10845Republic of Korea Department of Materials Science and Engineering Chosun UniversityGwangju 61452Republic of Korea Institute of Well-Aging Medicare&Chosun University LAMP Center Chosun UniversityGwangju 61452Republic of Korea Division of Materials Science and Engineering Hanyang UniversitySeoul 04763Republic of Korea Department of Mechanical Engineering École de Technologie SupérieureMontrealQuebec H3C 1K3Canada Material&Component Convergence R&D Center Korea Construction Equipment Technology InstituteGunsanJeollabuk-do 54002Republic of Korea School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore Graduate Institute of Ferrous&Eco Materials Technology Pohang University of Science and TechnologyPohangGyeongsangbuk-do 37673Republic of Korea Advanced Institute for Materials Research Tohoku UniversitySendai 980-8577Japan Institute for Convergence Research and Education in Advanced Technology Yonsei UniversitySeoul 03722Republic of Korea School of Mechanical and Materials Engineering Washington State UniversityPullmanWashington 99164USA School of Mechanical Engineering Purdue UniversityWest LafayetteIndiana 47907USA Research Institute of Advanced Manufacturing Technology Korea Institute of Industrial TechnologyIncheon 21999Republic of Korea Department of Macromolecular Science and Engineering Case Western Reserve UniversityClevelandOhio 44106USA Department of Chemical and Biomolecular Engineering and Joint Institute for Advanced Materials University of TennesseeKnoxvilleTennessee 37996USA Center for nanophase Materials and Sciences Oak Ridge National LaboratoryOak RidgeTennessee 37830USA Department of Mechanical Engineering University of New BrunswickFrederictonNew Brunswick E3B 5A3Cana

The ex-situ incorporation of the secondary SiC reinforcement,along with the in-situ incorporation of the tertiary and quaternary Mg_(3)n_(2) and Si_(3)n_(4) phases,in the primary matrix of Mg_(2)Si is employed in order to provide ultimate wear resistance based on the laser-irradiation-induced inclusion of n_(2) gas during laser powder bed *** is substantialized based on both the thermal diffusion-and chemical reactionbased metallurgy of the Mg_(2)Si–SiC/nitride hybrid *** study also proposes a functional platform for systematically modulating a functionally graded structure and modeling build-direction-dependent architectonics during additive *** strategy enables the development of a compositional gradient from the center to the edge of each melt pool of the Mg_(2)Si–SiC/nitride hybrid ***,the coefficient of friction of the hybrid composite exhibits a 309.3%decrease to–1.67 compared to–0.54 for the conventional nonreinforced Mg_(2)Si structure,while the tensile strength exhibits a 171.3%increase to 831.5 MPa compared to 485.3 MPa for the conventional *** outstanding mechanical behavior is due to the(1)the complementary and synergistic reinforcement effects of the SiC and nitride compounds,each of which possesses an intrinsically high hardness,and(2)the strong adhesion of these compounds to the Mg_(2)Si matrix despite their small sizes and low concentrations.

关键词： Laser powder bed fusion Mg_(2)Si-SiC/nitride hybrid composite Both the thermal diffusion-and chemical reaction-based metallurgy Functionally graded structure Compositional gradient Wear resistance.

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音乐治疗可以改善自闭症者的注意能力吗?

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中国音乐 2024年第3期 197-205页

作者：许洁江俊王莞琪上海音乐学院声乐歌剧系上海师范大学音乐学院上海师范大学心理学院上海师范大学教育发展基金会

自闭症是一种严重影响患者社交互动和行为表现的神经发育障碍,对全球公共卫生构成了重大挑战。尽管自闭症者可能面临许多困难,但他们通常具有良好的音乐能力,使音乐治疗成为潜在的康复手段。然而,音乐治疗是否能够改善自闭症症状尚不明... 详细信息

自闭症是一种严重影响患者社交互动和行为表现的神经发育障碍,对全球公共卫生构成了重大挑战。尽管自闭症者可能面临许多困难,但他们通常具有良好的音乐能力,使音乐治疗成为潜在的康复手段。然而,音乐治疗是否能够改善自闭症症状尚不明确。本研究基于注意加工可能是自闭症的核心假设,探讨了自闭症者的注意障碍,并评估了音乐治疗对其注意能力的影响。研究结果显示,自闭症者具有注意障碍;在训练与测试任务相似的情况下,被动接受式、主动参与式或综合性的音乐治疗都能提高其注意能力。这些结果为自闭症治疗提供了有益的参考,证实了音乐治疗的有效性,同时为缓解自闭症症状提供了新思路。

关键词：音乐治疗自闭症注意执行功能紊乱理论测验

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Elucidating the dynamics of polymer transport through nanopores using asymmetric salt concentrations

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nano Research 2022年第11期15卷 9943-9953页

作者： Martin Charron Lucas philipp Liqun He Vincent Tabard-Cossa Department of Physics University of OttawaOttawaON K1N 6N5Canada

While notable progress has been made in recent years both experimentally and theoretically in understanding the highly complex dynamics of polymer capture and transport through nanopores,there remains significant disagreement between experimental observation and theoretical prediction that needs to be *** salt concentrations,where the concentrations of ions on each side of the membrane are different,can be used to enhance capture rates and prolong translocation times of electrophoretically driven polymers translocating through a nanopore from the low salt concentration reservoir,which are both attractive features for single-molecule ***,since asymmetric salt concentrations affect the electrophoretic pull inside and outside the pore differently,it also offers a useful control parameter to elucidate the otherwise inseparable physics of the capture and translocation *** this work,we attempt to paint a complete picture of the dynamics of polymer capture and translocation in both symmetric and asymmetric salt concentration conditions by reporting the dependence of multiple translocation metrics on voltage,polymer length,and salt concentration *** asymmetric salt concentration conditions,we experimentally observe the predictions of tension propagation theory,and infer the significant impact of the electric field outside the pore in capturing polymers and in altering polymer conformations prior to translocation.

关键词： nanopore DnA translocation salt gradient tension propagation polymer transport

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Observation of a single protein by ultrafast X-ray diffraction

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Light(Science & Applications) 2024年第1期13卷 80-90页

作者： Tomas Ekeberg Dameli Assalauova Johan Bielecki Rebecca Boll Benedikt J.Daurer Lutz A.Eichacker Linda E.Franken Davide E.Galli Luca Gelisio Lars Gumprecht Laura H.Gunn Janos Hajdu Robert Hartmann Dirk Hasse Alexandr Ignatenko Jayanath Koliyadu Olena Kulyk Ruslan Kurta Markus Kuster Wolfgang Lugmayr Jannik Lübke Adrian P.Mancuso Tommaso Mazza Carl nettelblad Yevheniy Ovcharenko Daniel E.Rivas Max Rose Amit K.Samanta philipp Schmidt Egor Sobolev nicusor Timneanu Sergey Usenko Daniel Westphal Tamme Wollweber Lena Worbs Paul Lourdu Xavier Hazem Yousef Kartik Ayyer Henry n.Chapman Jonas A.Sellberg Carolin Seuring Ivan A.Vartanyants Jochen Küpper Michael Meyer Filipe R.n.C.Maia Laboratory of Molecular Biophysics Department of Cell and Molecular BiologyUppsala UniversityHusargatan 3(Box 596)SE-75124 UppsalaSweden Deutsches Electronen-Synchrotron DESY Notkestrasse 8522607 HamburgGermany European XFEL Holzkoppel 422869 SchenefeldGermany Diamond Light Source Harwell Science&Innovation CampusDidcot OX110DEUK University of Stavanger Centre Organelle ResearchRichard-Johnsensgate 44021 StavangerNorway Leibniz Institute for Experimental Virology(HPI) Centre for Structural Systems BiologyNotkestraße 8522607 HamburgGermany Dipartimento di Fisica“Aldo Pontremoli” Universitàdegli Studi di Milanovia Celoria 1620133 MilanoItaly Center for Free-Electron Laser Science DESY22607 HamburgGermany Plant Biology Section School of Integrative Plant ScienceCornell UniversityIthacaNY 14853USA PnSensor GmbH Otto-Hahn-Ring 6D-81739 MünchenGermany Biomedical and X-Ray Physics Department of Applied PhysicsAlbaNova University CenterKTH Royal Institute of TechnologySE-10691 StockholmSweden ELI Beamlines/IoP Institute of Physics AS CR v.v.i.Na Slovance 218221 Prague 8Czech Republic Multi-User CryoEM Facility Centre for Structural Systems BiologyNotkestr.8522607 HamburgGermany University Medical Center Hamburg-Eppendorf(UKE) Martinistrasse 5220246 HamburgGermany The Hamburg Center for Ultrafast Imaging Universität HamburgLuruper Chaussee 14922761 HamburgGermany Department of Physics Universität HamburgLuruper Chaussee 14922761 HamburgGermany Department of Chemistry and Physics La Trobe Institute for Molecular ScienceLa Trobe UniversityMelbourneVIC 3086Australia Division of Scientific Computing Science for Life LaboratoryDepartment of Information TechnologyUppsala UniversityBox 337SE-75105 UppsalaSweden European Molecular Biology Laboratory c/o DESYNotkestrasse 8522607 HamburgGermany Department of Physics and Astronomy Uppsala UniversityBox 516SE-75120 UppsalaSweden Max Planck Institute for the Structure and Dynamics of Matter Luruper Chaussee 14922761 HamburgGe

The idea of using ultrashort X-ray pulses to obtain images of single proteins frozen in time has fascinated and inspired *** was one of the arguments for building X-ray free-electron *** to theory,the extremely intense pulses provide sufficient signal to dispense with using crystals as an amplifier,and the ultrashort pulse duration permits capturing the diffraction data before the sample inevitably *** was first demonstrated on biological samples a decade ago on the giant *** then,a large collaboration has been pushing the limit of the smallest sample that can be *** ability to capture snapshots on the timescale of atomic vibrations,while keeping the sample at room temperature,may allow probing the entire conformational phase space of *** we show the first observation of an X-ray diffraction pattern from a single protein,that of Escherichia coli GroEL which at 14 nm in diameter is the smallest biological sample ever imaged by X-rays,and demonstrate that the concept of diffraction before destruction extends to single *** the pattern,it is possible to determine the approximate orientation of the *** experiment demonstrates the feasibility of ultrafast imaging of single proteins,opening the way to single-molecule time-resolved studies on the femtosecond timescale.

关键词： smallest intense ultrafast

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Validation of ERA5-Land temperature and relative humidity on four Peruvian glaciers using on-glacier observations

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Journal of Mountain Science 2022年第7期19卷 1849-1873页

作者： BOnSHOMS Martí UBEDA Jose LIGUORI Giovanni KORnER philipp nAVARRO Alvaro CRUZ Rolando Departamento de Geografía Universidad Complutense de MadridMadrid 28040Spain Guías de Espeleología y Montana Torremocha del Jarama 28189Spain Department of Physics and Astronomy University of BolognaBologna 40127Italy School of Earth Atmosphere and EnvironmentMonash UniversityMelbourne 3800Australia Institute of Hydrology and Meteorology Technische Universitat DresdenDresden 01737Germany ESRI-Espana Madrid 28037Spain Area de Evaluación de Glaciares y Lagunas.Autoridad nacional del Agua Huaraz 02002Peru

Weather and climate conditions drive the evolution of tropical glaciers which play an important role as water reservoirs for Peruvian inhabitants in the arid coast and semi-arid Andean *** scarcity of long-term high-quality observations over Peruvian glaciers has motivated the extensive use of reanalysis data to describe the climatic evolution of these ***,the representativeness and uncertainties of these reanalysis products over these glaciers are still poorly *** study evaluates the ability of the ERA-Land reanalysis(ERAL)to reproduce hourly and monthly 2 m air temperature and relative humidity(T2m and Rh2m,respectively)over several Peruvian *** compared the ERAL with data from four on-glacier automatic weather stations(AWS),whose hourly time series were completed with nearby stations,for the period January 2017 to December *** indicates a better performance of the reanalysis for T2m(r>0.80)than for Rh2m(~0.4n all four *** the observations,both parameters show a daily cycle influenced by the presence of the *** influence is more prominent during the dry months when the so-called glacier damping and cooling effects are *** a monthly time scale,the ERAL validation for both parameters are better in wet outer tropical sites(RMSE between±0.2℃ for T2m and between 3%-7% for Rh2m)rather than in dry outer tropical sites(RMSE between±0.2℃ for T2m and between 3%-7% for Rh2m).Among all sites considered in the study,the Rh2m bias is the highest in the Cavalca glacier(correlation of 0.81;RMSE 13%,MAE 11% and bias 8.3%)and the lowest in Artesonraju glacier(correlation of 0.96;RMSE 3%;MAE 2.3% and bias-0.8%).Based on certain considerations outlined in this paper,it is appropriate to use ERAL to characterize T2m and Rh2m conditions on Peruvian glaciers,particularly in the wet outer tropics.

关键词： ERA5 Land Tropical glaciers Temperature Relative humidity Peru Validation

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Retinal microvascular signs and recurrent vascular events in patients with TIA or minor stroke

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Stroke & Vascular neurology 2023年第5期8卷 379-386,I0001-I0007页

作者： philipp Klyscz Thomas Ihl Inga Laumeier Maureen Steinicke Matthias Endres Georg Michelson Heinrich J Audebert neurology Charité-Universitätsmedizin BerlinBerlinGermany Center for Stroke Research Berlin Charité-Universitätsmedizin BerlinBerlinGermany Berlin Institute of Health BerlinGermany Excellence Cluster neuroCure Charité-Universitätsmedizin BerlinBerlinGermany German Center for neurodegenerative Diseases partner site BerlinGermany German Center for Cardiovascular Research partner site BerlinGermany Ophthalmology Friedrich-Alexander-Universität Erlangen-Nürnberg Medizinische FakultätErlangenGermany Talkingeyes&More GmbH ErlangenGermany

Background and purpose Retinal pathologies are an independent risk factor for ischaemic stroke,but research on the predictive value of retinal abnormalities for recurrent vascular events in patients with prior stroke is *** investigated the association of retinal pathologies with subsequent vascular *** In a substudy of the Intensified secondary prevention intending a reduction of recurrent events in TIA and minor stroke patients(InSPiRE-TMS)trial,we enrolled patients with recent transient ischaemic attack(TIA)or minor stroke with at least one modifiable risk *** outcome was the composite of subsequent vascular *** photographs were taken at baseline and categorised into three different fundus groups by a telemedically linked *** 722 patients participated in the current study and 109 major vascular events *** multivariable adjustments,we did not find a significant association between fundus categories and risk for subsequent vascular events(HRs for moderate vascular retinopathy and vascular retinopathy with vessel rarefaction in comparison to no vascular retinopathy 1.03(95%CI 0.64 to 1.67),p=0.905 and 1.17(95%CI 0.62 to 2.20),p=0.626).In a selective post hoc analysis in patients with diabetes mellitus and hypertension,patients with vascular retinopathy with vessel rarefaction had a higher risk for recurrent stroke(HR 24.14(95%CI 2.74 to 212.50),p=0.004).Conclusions Retinal changes did not predict major subsequent vascular events in patients with recent TIA or minor *** studies are needed to examine the utility of fundus photography in assessing the risk of stroke recurrence in patients with diabetes mellitus and hypertension.

关键词： patients Retinal prevention

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猪源GSDMD蛋白多克隆抗体的制备及初步应用

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中国兽医科学 2024年第7期54卷 968-973页

作者：刘佳宋洁李帅王尚辉李江南王春凤翁长江曾艳吉林农业大学动物医学学院吉林长春130118 中国农业科学院哈尔滨兽医研究所动物疫病防控全国重点实验室黑龙江哈尔滨150069 黑龙江省兽医免疫重点实验室黑龙江哈尔滨150069

为制备猪源GSDMD多克隆抗体,构建了重组表达质粒pET-21a-nGSDMD,成功表达并纯化了重组nGSDMD蛋白。将纯化的重组蛋白免疫新西兰大白兔制备nGSDMD多克隆抗体(pAb),经ELISA检测,抗体效价为1∶64000。Western-blot和IFA显示该抗体能特异性... 详细信息

为制备猪源GSDMD多克隆抗体,构建了重组表达质粒pET-21a-nGSDMD,成功表达并纯化了重组nGSDMD蛋白。将纯化的重组蛋白免疫新西兰大白兔制备nGSDMD多克隆抗体(pAb),经ELISA检测,抗体效价为1∶64000。Western-blot和IFA显示该抗体能特异性识别HEK293T细胞中瞬时表达的Flag-GSDMD蛋白和PRRSV感染肺泡巨噬细胞(PAMs)后表达的GSDMD蛋白。该多克隆抗体特异性良好,无交叉反应,能识别检测病毒感染条件下GSDMD切割片段,可用于PRV和PRRSV诱导的细胞焦亡检测。综上,本研究为探究GSDMD蛋白提供了良好的工具,为深入探究GSDMD蛋白的生物学功能奠定了基础。

关键词：猪源GSDMD 多克隆抗体效价初步应用

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不同光质对藏川杨生长及光合特性的影响

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西南农业学报 2024年第5期37卷 1019-1027页

作者：刘金萍王静敏陈智华马少杰纵丹何承忠西南林业大学/云南省高校林木遗传改良与繁育重点实验室昆明650224 西南林业大学/西南山地森林资源保育与利用教育部重点实验室昆明650224

【目的】研究不同光质对藏川杨幼苗生长和光合特性的影响,进一步探究藏川杨对高原地区强光环境的响应,为高光效杨树的筛选提供理论依据。【方法】以当年生藏川杨扦插苗为试材,设置白、蓝、绿3种颜色薄膜,以白膜为对照,测定分析生长及生... 详细信息

【目的】研究不同光质对藏川杨幼苗生长和光合特性的影响,进一步探究藏川杨对高原地区强光环境的响应,为高光效杨树的筛选提供理论依据。【方法】以当年生藏川杨扦插苗为试材,设置白、蓝、绿3种颜色薄膜,以白膜为对照,测定分析生长及生理指标、叶绿素荧光和光合参数。【结果】蓝膜和绿膜均显著提高藏川杨幼苗株高,分别提高28.1%和38.5%,而蓝膜显著减小幼苗叶宽,降低33.3%;蓝膜显著增加幼苗叶片光合色素(31.74%)、可溶性总糖(55.57%)和蔗糖含量(78.58%),而绿膜则显著减少幼苗叶片可溶性总糖和淀粉积累;蓝膜可提高光下PSⅡ电子传递量子产率(Φ_(PSⅡ)),降低非光化学淬灭系数(nPQ),而绿膜显著降低电子传递速率(ETR)和Φ_(PSⅡ),提高nPQ;3种颜色薄膜处理下藏川杨叶片净光合速率(P_(n))的日变化曲线均呈“双峰型”,整体P_(n)数值大小顺序为蓝膜>白膜>绿膜,不同颜色薄膜处理下藏川杨叶片均在12:00时出现光合午休现象。气孔导度(G_(s))和蒸腾速率(T_(r))总体变化趋势与P_(n)类似,而胞间CO_(2)浓度(C_(i))则呈“W型”曲线;蓝膜显著提高了藏川杨叶片最大净光合速率(P_(n max))、光补偿点(LCP)、CO_(2)饱和点(CCP),绿膜降低其最大净光合速率(P_(n max))、暗呼吸速率(R_(d))和光补偿点(LCP),显著提高光呼吸速率(R_(p))、CO_(2)补偿点(CCP)。【结论】生长环境中的光质能够影响藏川杨的光合效率及生长发育。通过覆盖蓝色薄膜改善光质能增强藏川杨幼苗叶片光合色素含量、提高弱光和CO_(2)利用率、提高光合效率、增强光合产物积累、促进植株生长。

关键词：光质藏川杨叶绿素荧光幼苗生长光合特性

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n1s Electron Binding Energies of Cn_x Thin Films Grown by Magnetron Sputtering at Different Temperature

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Journal of Materials Science & Technology 1998年第1期14卷 25-28页

作者： Zheng, WT Xing, KZ Hellgren, n Ivanov, I Salaneck, WS Sundgren, je Linkoping Univ Dept Phys S-58183 Linkoping Sweden

Carbon nitride thin films deposited using dc unbalanced magnetron sputtering system have been analyzed by X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy. The XPS data show that n1s binding states depend on substrate temperature T-s, in which the peak at 400.0 eV increases with T-s, whereas the peak at 398.3 eV decreases with T-s slightly. On the basis of XPS, FTIR and Raman spectra, the assignment of n1s electron binding energies was made. The peak at 400.0 eV is attributed to n atoms bonded to sp(2) coordinated C atoms. The peak at 398.3 eV is attributed to n atoms bonded to sp(3) coordinated C atoms as well as n-C bonds.

关键词： Thin films

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Mode structure symmetry breaking of reversed shear Alfvén eigenmodes and its impact on the generation of parallel velocity asymmetries in energetic particle distribution

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Plasma Science and Technology 2022年第2期24卷 17-27页

作者：孟果 philipp LAUBER 王鑫卢志鑫 Max-Planck-Institut für Plasmaphysik D-85748 GarchingGermany

In this work,the gyrokinetic eigenvalue code LIGKA,the drift-kinetic/MHD hybrid code HMGC and the gyrokinetic full-f code TRIMEG-GKX are employed to study the mode structure details of reversed shear Alfvén eigenmodes(RSAEs).Using the parameters from an ASDEXUpgrade plasma,a benchmark with the three different physical models for RSAE without and with energetic particles(EPs)is carried *** agreement has been found for the mode frequency and the growth *** structure symmetry breaking(MSSB)is observed when EPs are included,due to the EPs’non-perturbative *** is found that the MSSB properties are featured by a finite radial wave phase velocity,and the linear mode structure can be well described by an analytical complex Gaussian expressionФ(s)=e^(-σ(s-s_(0))^(2))with complex parametersσand s_(0),where s is the normalized radial *** mode structure is distorted in opposite manners when the EP drive shifted from one side of qminto the other side,and specifically,a non-zero average radial wave number with opposite signs is *** initial EP density profiles and the corresponding mode structures have been used as the input of HAGIS code to study the EP *** parallel velocity of EPs is generated in opposite directions,due to different values of the average radial wave number,corresponding to different initial EP density profiles with EP drive shifted away from the qmin.

关键词： reversed shear Alfvén eigenmode symmetry breaking energetic particles non-perturbative effects

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