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Observation of an Even-Odd Asymmetric Transport in High Landau Levels

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Chinese Physics Letters 2017年第3期34卷 112-116页

作者：刘广同朱玉莹王钦庞远樊洁景秀年姬忠庆杨昌黎吕力杜瑞瑞 L.n.pfeiffer K.W.West Daniel Chee Tsui Laboratory Beijing National Laboratory for Condensed Matter PhysicsInstitute of PhysicsChinese Academy of SciencesBeijing 100190 Collaborative Innovation Center of Quantum Matter Beijing 100871 International Center for Quantum Materials Peking UniversityBeijing 100871 Department of Electrical Engineering Princeton UniversityPrincetonNew Jersey 08544USA

Magnetotransport experiments including tilt fields are performed on ultrahigh mobility L-shaped Hall-bar samples of GaAs/AlGaAs quantum wells. The low-temperature longitudinal resistivity （ρxx） data demonstrate that a striking even-odd asymmetric transport exists along the [110] direction at half filling in n ≥ 2 high Landau levels. Although the origin for the peculiar even-odd asymmetry remains unclear, we propose that the coupling strength between electrons within the same Landau level and between the neighboring two Landau levels should be considered in future studies. The tilt field data show that the in-plane field can suppress the formation of both bubble and stripe phases.

关键词： Observation of an Even-Odd Asymmetric Transport in High Landau Levels 110

Quantum hydrodynamics of a single particle

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Light(Science & Applications) 2020年第1期9卷 1199-1205页

作者： Daniel Gustavo Suarez-Forero Vincenzo Ardizzone Saimon Filipe Covre da Silva Marcus Reindl Antonio Fieramosca Laura Polimeno Milena De Giorgi Lorenzo Dominici Loren n.pfeiffer Giuseppe Gigli Dario Ballarini Fabrice Laussy Armando Rastelli Daniele Sanvitto CnR nAnOTEC Institute of NanotechnologyCampus EcotekneVia Monteroni73100 LecceItaly Dipartimento di Ingegneria dell’Innovazione Universita del SalentoCampus Ecoteknevia Monteroni73100 LecceItaly Institute of Semiconductor and Solid State Physics Johannes Kepler UniversityAltenbergerstr.69Linz 4040Austria Dipartimento di Matematica e Fisica E.De Giorgi Universita del SalentoCampus Ecoteknevia MonteroniLecce 73100Italy PRISM Princeton Institute for the Science and Technology of MaterialsPrinceton UniversityPrincetonNJ 08540USA Faculty of Science and Engineering University of WolverhamptonWulfruna StreetWolverhampton WV11LYUK Russian Quantum Center Novaya 100143025 SkolkovoMoscow RegionRussia

Semiconductor devices are strong competitors in the race for the development of quantum computational *** this work,we interface two semiconductor building blocks of different dimensionalities with complementary properties:(1)a quantum dot hosting a single exciton and acting as a nearly ideal single-photon emitter and(2)a quantum well in a 2D microcavity sustaining polaritons,which are known for their strong interactions and unique hydrodynamic properties,including ultrafast real-time monitoring of their propagation and phase *** the present experiment,we can thus observe how the injected single particles propagate and evolve inside the microcavity,giving rise to hydrodynamic features typical of macroscopic systems despite their genuine intrinsic quantum *** the presence of a structural defect,we observe the celebrated quantum interference of a single particle that produces fringes reminiscent of wave *** this behavior could be theoretically expected,our imaging of such an interference pattern,together with a measurement of antibunching,constitutes the first demonstration of spatial mapping of the self-interference of a single quantum particle impinging on an obstacle.

关键词： quantum particle hydrodynamic

青光眼患者血清抗视网膜抗原的抗体轮廓质谱分析

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中华眼科杂志 2009年第7期45卷 625-630页

作者：严良 Joachim S. C pfeiffer n Grus F.H Erb C 上海市宝山中心医院眼科 201900 Experimental Ophthalmology Department of Ophthalmology Johannes Gutenberg University Mainz Germany Department of Ophthalmology Schlosspark Klinik Berlin Germany

目的比较原发性开角型青光眼（POAG）患者与正常对照（CTRL）者间的抗体轮廓差异。方法病例对照研究。将44例POAG患者与48例CTRL者的血清分别加入到含有预洗Dyna珠-G蛋白的反应管中，以捕获人免疫球蛋白G（IgG）抗体，形成的IgG—G蛋白... 详细信息

目的比较原发性开角型青光眼（POAG）患者与正常对照（CTRL）者间的抗体轮廓差异。方法病例对照研究。将44例POAG患者与48例CTRL者的血清分别加入到含有预洗Dyna珠-G蛋白的反应管中，以捕获人免疫球蛋白G（IgG）抗体，形成的IgG—G蛋白复合体用来捕获目标抗原（匀质化牛视网膜组织）。经洗提后获得的抗原蛋白通过“表面增强激光解吸附-电离-飞行时间-质谱”仪进行检测。采用Proteomic software project统计学软件，对两组质谱数据连同受检者年龄和性别等参数，自动进行t检验和初步多变量判别分析；随后采用Statistica version8．0统计学软件，进行包括抗原蛋白质谱数据、蛋白质芯片类型和激光解吸附-电离能量等的多变量判别分析。结果CTRL组的平均质谱强度为4244．427±4721．115，POAG组为4049．864±4083．819，两组间差异有统计学意义（F=1．340，P〈0．01）；在POAG患者中，出现了部分高调节免疫反应，但主要表现为低调节免疫反应。结论在POAG患者与CTRL者之间存在明显的抗体轮廓差异，在POAG组中出现的低调节免疫反应表明部分患者可能与“异常免疫”有关。

关键词：青光眼开角型自身免疫自身抗体光谱法质量基质辅助激光解吸电离

青光眼患者的自身抗体:抗视网膜、视神经及视神经乳头抗原的IgG血清抗体的对照研究

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世界核心医学期刊文摘(眼科学分册) 2006年第1期 40-41页

作者： Joachim S.C. pfeiffer n. Grus F.H. 张鹏 Department of Ophthalmology University of Mainz Langenbeckstrasse 1 55101 Mainz Germany

Purpose: The aim of this study was to analyze and compare the entire IgG autoantibody patterns against different ocular antigens (retina, optic nerve, and optic nerve head) in sera of glaucoma patients and healthy subjects. Methods: Sixty-six patients were included in this study: healthy volunteers without any ocular disorders (CO, n=30), patients with primary open-angle glaucoma (POAG, n=19), and patients with normal-tension glaucoma (nTG, n=17). The sera were tested for antibodies against retinal, optic nerve, and optic nerve head tissues. Immunodetection was performed using 4-chloro-1-naphthol staining. The autoantibody patterns were digitized and subsequently analyzed by multivariate statistical techniques. Results: All patients showed a complex repertoire of IgG antibodies against retinal, optic nerve, and optic nerve head antigens. The analysis of discriminance revealed a statistically significant differences between the patterns of all three groups. Our multivariate approach could quantify the differences in immunore activities of patient sera against the three antigens. The POAG group had the most significant difference against retinal antigens (P=0.0021) compared with the other antigens. In the nTG group the highest reactivity appeared against optic nerve head (P=0.00053) and optic nerve (P=0.0025). Conclusions: All groups showed different and complex antibody patterns against the three ocular tissues. These autoantibodies are highly specific for each patient group. The analysis of these patterns could provide further information about possible autoimmune mechanisms in the pathogenesis of glaucoma.

关键词：视神经乳头视网膜 IgG 青光眼自身抗体患者抗原

Dynamic ordering transitions in charged solid

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Fundamental Research 2022年第2期2卷 178-183页

作者： Jian Sun Jiasen niu Yifan Li Yang Liu Lnpfeiffer KWWest Pengjie Wang Xi Lin International Center for Quantum Materials Peking UniversityBejjing 100871China Department of Electrical Engineering Princeton UniversityPrincetonNew Jersey 08544USA Department of Physics Princeton UniversityPrincetonNew Jersey 08544USA Beijing Academy of Quantum Information Sciences Beijing 100193China CAS Center for Exellence in Topological Quantum Computation University of Chinese Academy of SciencesBeijing 100190China

The phenomenon of group motion is common in nature,ranging from the schools of fish,birds and insects,to avalanches,landslides and sand *** we treat objects as collectively moving particles,such phenomena can be studied from a physical point of view,and the research on many-body systems has proved that marvelous effects can arise from the simplest *** motion of numerous individuals presents different dynamic phases related to the ordering of the ***,it is usually difficult to study the dynamic ordering and its transitions through *** bubble states formed in a two-dimensional electron gas,as a type of electron solids,can be driven by an external electric field and provide a platform to study the dynamic collective ***,we demonstrate that the noise spectrum is a powerful method to investigate the dynamics of bubble *** observed not only the phenomena of dynamically ordered and disordered structures,but also unexpected alternations between *** results show that a dissipative system can convert between chaotic structures and ordered structures when tuning global parameters,which is concealed in conventional transport measurements of resistance or ***,charging the objects to study the electrical noise spectrum in collective motions can be an additional approach to revealing dynamic ordering transitions.

关键词： Two-dimensional system Electron solid Dynamic ordering transition noise spectrum measurement Collective motion

nucleoside modified mRnA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： Krisztián Pajer Tamás Bellák Antal nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(Khyeam et al.,2021).

关键词： injured capacity modified

Calculation of Electron Swarm Parameters of SF_6/n_2 in a Uniform Field Using an Improved Monte Carlo Collision Simulation Method

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Plasma Science and Technology 2008年第1期10卷 39-42页

作者：汪沨 W.pfeiffer n.KOUZICHInE 邱毓昌 E.KUFFEL 李肯立 School of Electrical and Information Engineering Hunan University Changsha 410082. China Technische Universitt Darmstadt 64283 Darmstadt Germany School of Electrical Engineering Xi'an Jiaotong University Xi'an 710049 China Department of Electrical Engineering and Computer Science University of Manitoba Winnipeg Canada School of Computor and Communication Huna University Changsha 410084 China

The electron swarm parameters of SF6/n2 are calculated in the present study using an improved Monte Carlo collision simulation method （MCS）. And some improved sampling techniques are also adopted. The simulation res... 详细信息

关键词： Monte Carlo collision simulation gas discharge swarm parameter

Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular events,where nuclear factor-κB serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prevent central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

Sex differences in aging and injured brain

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neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan n.Williamson Yuan Yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic