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Journal of Cancer Therapy 2014年第12期5卷 1059-1064页

作者： peter k. donnelly Louise Robinson Matt Halk.s Andy Goodman Department of Breast Surgery Torbay Hospital South Devon Healthcare NHS Foundation Trust Torquay UK Department of Anaesthesia Torbay Hospital South Devon Healthcare NHS Foundation Trust Torquay UK Department of Oncology Torbay Hospital South Devon Healthcare NHS Foundation Trust Torquay UK

The aim of this case report is to present a novel approach to the management of very severe anaphylactic reaction to Patent Blue Dye used in Sentinel Node Biopsy for breast cancer treatment. The severity and duration of cardiovascular effects has not been described previously in this setting. Comprehensive ICU support including heamofiltration resulted in the patients’ complete recovery and successful long-term well-being despite a change to our routine cancer care plan.

关键词： Blue Dye Anaphylaxis Sentinel Node Haemofiltration Breast Cancer

Automated bolting and meshing on a continuous miner for roadway development

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International Journal of Mining Science and Technology 2013年第1期23卷 55-61页

作者： van Duin Stephen Meers Luk. donnelly peter Oxley Ian University of Wollongong Northfields Avenue Gwynneville NSW Australia

Automated installation of primary roof support material can potentially increase productivity and operator safety in the roadway development process within underground coal mining. Although the broader manufacturing sector has benefited from automation, several challenges exist within the Australian underground coal industry which mak.s it difficult to fully exploit these technologies. At the University of Wollongong a series of reprogrammable electromechanical manipulators have been designed to overcome these challenges and automatically handle the installation of roof and rib containment consumables on a continuous miner. The automated manipulation removes personnel from hazards in the immediate face area, particularly those associated with work.ng in a confined and unstable work.ng environment in close proximity to rotating and moving equipment. In a series of above ground trials the automated system was successfully demonstrated without human intervention and proven to be capable of achieving cycle times at a rate of 10 m per operating hour, consistent with that required to support high capacity longwall mines. The trials also identified a number of refinements which could further improve both cycle times and system reliability when considering the technology for underground use. The results have concluded that conventional manual handling practices on a continuous miner can be eliminated, and that the prototypes have significantly reduced the technical risk.in proceeding to a full underground trial.

关键词：自动化机器人学车道开发操作房顶支持

Management of symptomatic neuromas:a narrative review of the most common surgical treatment modalities in amputees

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Plastic and Aesthetic Research 2022年第1期9卷 120-132页

作者： Sahand C.Eftek.ri peter J.Nick.ic Allison J.Seitz D’Andrea T.donnelly Aaron M.Dingle Samuel O.Poore Division of Plastic Surgery University of Wisconsin School of Medicine and Public HealthG5-347 Clinical Sciences CenterMadisonWI 53711USA

Symptomatic neuromas are an all-too-common complication following limb amputation or extremity trauma,leading to chronic and debilitating pain for *** resection of symptomatic neuromas has proven to be the superior method of intervention,but traditional methods of neuroma resection do not address the underlying pathophysiology leading to the formation of a future symptomatic neuroma and lead to high reoperation *** approaches employ the physiology of peripheral nerve injury to harness the regeneration of nerves to their *** review explores the underlying pathophysiology of neuroma formation and centralization of pain *** compares the traditional surgical approach for symptomatic neuroma resection and describes three novel surgical strategies that harness this pathophysiology of neuroma formation to their *** traditional resection of symptomatic neuromas is currently the standard of care for amputation patients,but new techniques including the regenerative peripheral nerve interface,targeted muscle reinnervation,and intraosseous transposition have shown promise in improving patient pain outcomes for postamputation pain and residual limb *** neuromas are a chronic and debilitating complication following amputation procedures and trauma,and the current standard of care does not address the underlying pathophysiology leading to the formation of the *** techniques are under development that may provide improved patient pain outcomes and a higher level of care for symptomatic neuroma resection.

关键词： Neuromas regenerative peripheral nerve interface targeted muscle reinnervation osseointegrated neural interface amputation

Neoproterozoic tectonic geography of the south-east Congo Craton in Zambia as deduced from the age and composition of detrital zircons

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Geoscience Frontiers 2019年第6期10卷 2045-2061页

作者： Brandon L.Alessio Alan S.Collins peter Siegfried Stijn Glorie Bert De Waele Justin Payne donnelly B.Archibald Centre for Tectonics Resources and Exploration(TRaX)Dept of Earth SciencesThe University of AdelaideAdelaideSouth Australia 5005Australia GeoAfrica Prospecting Services cc ErosNamibia SRk.Consulting 1/10 Richardson StWest PerthWestern Australia 6005Australia Curtin University of Technology Kent StBentleyWestern Australia 6102Australia Centre for Tectonics Resources and Exploration(TRaX)School of Built and Natural EnvironmentsUniversity of South AustraliaAdelaideSouth Australia 5000Australia St.Francis Xavier University Physical Sciences Complex5009 Chapel SquareAntigonishNova Scotia B2G 2W5Canada

The Southern Irumide Belt(SIB)is an orogenic belt consisting of a number of lithologically varied Mesoproterozoic and Neoproterozoic terranes that were thrust upon each *** belt lies along the southwest margin of the Archaean to Proterozoic Congo Craton,and bears a Neoproterozoic tectonothermal overprint relating to the Neoproterozoic-Cambrian collision between the Congo and k.lahari *** preserves a record of about 500 million years of plate interaction along this part of the Congo *** zircon samples from the SIB were analysed for U-Pb and Lu-Hf isotopes,as well as trace element *** data are used to constrain sediment-source relationships between SIB terranes and other Gondwanan terranes such as the local Congo Craton and Irumide belt and wider afield to Madagascar(Azania)and *** correlations are then used to interpret the Mesoproterozoic to Neoproterozoic affinity of the rock. and evolution of the *** zircon samples from the Chewore-Rufunsa and k.cholola(previously referred to as Luangwa-Nyimba)terranes of the SIB yield zircon U-Pb age populations and evolvedε(Hf)(t)values that are similar to the Muva Supergroup found throughout eastern Zambia,primarily correlating with Ubendian-Usagaran(ca.2.05-1.80 Ga)phase magmatism and a cryptic basement terrane that has been suggested to underlie the Bangweulu Block.and Irumide *** data suggest that the SIB was depositionally connected to the Congo Craton throughout the *** more eastern Nyimba-Sinda terrane of the SIB(previously referred to as Petauk.-Sinda terrane)records detrital zircon ages andε(Hf)(t)values that correlate with ca.1.1-1.0 Ga magmatism exposed elsewhere in the SIB and Irumide *** ascribe this difference in age populations to the polyphase development of the province,where the sedimentary and volcanic rock. of the Nyimba-Sinda terrane accumulated in extensional basins that developed in the *** deposition wou

关键词： Detrital zircon geochronology Tectonics Hafnium isotopes Zambia Southern irumide belt Irumide belt

Late syn-to post-collisional magmatism in Madagascar:The genesis of the Ambalavao and Maevarano Suites

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Geoscience Frontiers 2019年第6期10卷 2063-2084页

作者： donnelly B.Archibald Alan S.Collins John D.Foden Justin L.Payne peter Holden Théodore Razak.manana Department of Earth Sciences St.Francis Xavier UniversityPhysical Sciences Complex5009 Chapel SquareAntigonishNSB2G 2W5Canada Centre for Tectonics Resources and Exploration(TRaX)Department of Earth SciencesThe University of AdelaideAdelaide 5005SAAustralia Centre for Tectonics Resources and Exploration(TRaX)School of Built and Natural EnvironmentsUniversity of South AustraliaMawson LakesSA5001Australia Research School of Earth Sciences The Australian National UniversityCanberraACT2601Australia Departement des Sciences de la Terre Universitede ToliaraToliara601Madagascar

The East African Orogen involves a collage of Proterozoic microcontinents and arc terranes that became wedged between older cratonic block. during the assembly of *** Ediacaran-Cambrian Ambalavao and Maevarano Suites in Madagascar were emplaced during the waning orogenic stages and consist of weak.y deformed to undeformed plutonic rock. and dyk.s of mainly porphyritic granite but also gabbro,diorite and charnock.te.U-Pb geochronological data date emplacement of the Ambalavao Suite to between ca.580 Ma and 540 Ma and the Maevarano Suite to between ca.537 Ma and522 *** and trace element concentrations are consistent with emplacement in a syn-to postcollisional tectonic setting as A-type(anorogenic) ***(δ^(18)O of 5.27‰-7.45‰) and hafnium(ε(Hf)(t) of-27.8 to-12.3) isotopic data from plutons in the Itremo and Antananarivo Domains are consistent with incorporation of an ancient crustal *** primitive δ^(18)O(5.27‰-5.32‰) andε(Hf)(t)(+0.0 to+0.2) isotopic values recorded in samples collected from the Ik.lamavony Domain demonstrate the isotopic variation of basement sources present in the Malagasy *** Hf isotopic composition of Malagasy zircon are unlik. more juvenile Ediacaran-Cambrian zircon sou rces elsewhere in the East African Orogen and,as such,Madagascar represents a distinct and identifiable detrital zircon source region in Phanerozoic sedimentary provenance *** together,these data indicate that high-T crustal anatexis,crustal assimilation and interaction of crustal material with mantle-derived melts were the processes operating during magma *** magmatism was coeval with polyphase deformation throughout Madagascar during the amalgamation of Gondwana and magmatism is interpreted to reflect lithospheric delamination of an extensive orogenic plateau.

关键词： Madagascar geology East African orogen Zircon geochronology Zircon oxygen and hafnium isotopes Post-collisional magmatism

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DirectX 从入门到精通

Role of inflammation and infection in the pathogenesis of human acute liver failure: clinical implications for monitoring and therapy

丛书名：美国微软出版社(Microsoft Press)授权中文版技术系列书

1999年

作者： (美)Bradley Bargen,peter donnelly

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastroenterology 2016年第26期22卷 5958-5970页

作者： Mhairi C donnelly peter C Hayes k.nneth J Simpson Department of Hepatology and Scottish Liver Transplant Unit Royal Infirmary of Edinburgh

Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multiorgan failure. The importance of immune dysregulation and acquisition of infection in the pathogenesis of acute liver failure and its associated complications is now recognised. In this review we discuss current think.ng regarding the role of infection and inflammation in the pathogenesis of and outcome in human acute liver failure, the implications for the management of such patients and suggest directions for future research.

关键词： Inflammation Neuroinflammation Acute liver failure Biomark.r Infection

The Importance of Both the Technical and Social Domains in Creating a Culture That Accelerates Improvement in Healthcare

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Health 2020年第12期12卷 1575-1582页

作者： Lane F. donnelly k.ren Frush John Shook.peter A. Schein Edgar H. Schein Stanford Medicine Center for Improvement School of Medicine Stanford University Palo Alto USA Department of Radiology School of Medicine Stanford University Palo Alto USA Center for Pediatric and Maternal Value Lucile Packard Children’s Hospital—Stanford Stanford Children’s Health Palo Alto USA Department of Emergency Medicine School of Medicine Stanford University Palo Alto USA Office of the Chief Quality Officer Stanford Health Care Palo Alto USA Lean Enterprise Institute Boston USA Organizational Culture and Leadership Institute Menlo Park USA

Driving improvement in healthcare can be challenging related in part related to the degree of complexity. We break.down the aspects of culture needed to accelerate improvement into a technical domain and a social domain. Task.processes can be considered an organization’s technical domain. The social processes, how those doing the work.interact, can be thought of as the organization’s social domain. The technical domain focuses on the work.related to task. and the social domain on the relationships that mak. efficient and effective work.possible. We argue that work.requirements and social relations are inexorably intertwined—each profoundly impacting, reflecting, and even determining the other. In this review, we argue that in order to accelerate healthcare system improvement, focus must be given to processes that tak. into consideration both on the social and technical domains.

关键词： Improvement Culture Sociotechnical

青少年受欺负的跨国时间趋势--基于2002-2010年33个国家11岁、13岁和15岁调查数据的分析

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预防青少年犯罪研究 2017年第3期 112-118页

作者：凯莉L.切斯特 Mary Callaghan Alina Cosma peter donnelly Wendy Craig Sophie Walsh Michal Molcho 周华珍 Meng Jingjing 赫特福德大学英国哈特菲尔德爱尔兰国立大学卫生科学学院爱尔兰戈尔韦巴贝什-鲍里亚大学罗马尼亚克卢日-纳波卡圣安德鲁斯大学苏格兰圣安德鲁斯女王大学加拿大金士顿巴伊兰大学以色列拉马特甘爱尔兰国立大学卫生科学学院中国青年政治学院青少年健康研究中心

青少年受欺负是全球共同面临的公共卫生问题,严重地影响青少年的身心健康。学龄儿童健康行为(HBSC)国际研究网络对33个国家11岁、13岁、15岁在校学生近十年校园受欺负行为问卷调查的数据显示了该现象的跨国时间趋势。

关键词：青少年受欺负跨国时间趋势

2002-2010年欧洲和北美28个国家15岁青少年在同时吸烟和大麻方面的趋势

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预防青少年犯罪研究 2017年第5期 114-118页

作者：安妮·哈勃利特周华珍(译) Pemille Bendtse Margreet E.de Looze peter donnelly Runar Vilhjalmsson Tibor Bask. k.trin Aasvee Iva P.Franelic SaoirseNic Gabhainn Tom F.M.ter Bogt AnastasiosFotiou 根特大学公共卫生系中国青年政治学院青少年健康研究中心南丹麦大学国家公共卫生研究所乌特勒支大学社会科学跨学科研究所圣安德鲁斯大学医学院冰岛大学护理学院夸美纽斯大学Jessenius医学院国立健康发展研究所慢性病系克罗地亚国立公共卫生研究所爱尔兰国立大学健康促进研究中心大学精神健康研究所流行病学部

吸食大麻和吸烟经常共现,同时吸烟和大麻的青少年更容易出现呼吸困难和社会心理问题。本文运用"世界卫生组织-学龄儿童健康行为"模型收集了欧洲和北美33个参与国家在2002-2010年间有关15岁青少年在吸烟和吸食大麻方面的时间变化趋势。

关键词：青少年吸烟和吸食大麻共现时间变化趋势