Management of symptomatic neuromas:a narrative review of the most common surgical treatment modalities in amputees
作者机构：Division of Plastic SurgeryUniversity of Wisconsin School of Medicine and Public HealthG5-347 Clinical Sciences CenterMadisonWI 53711USA
出 版 物：《Plastic and Aesthetic Research》 (整形与美容研究（英文版）)
年 卷 期：2022年第9卷第1期
页 面：120-132页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Neuromas regenerative peripheral nerve interface targeted muscle reinnervation osseointegrated neural interface amputation
摘 要：Symptomatic neuromas are an all-too-common complication following limb amputation or extremity trauma,leading to chronic and debilitating pain for *** resection of symptomatic neuromas has proven to be the superior method of intervention,but traditional methods of neuroma resection do not address the underlying pathophysiology leading to the formation of a future symptomatic neuroma and lead to high reoperation *** approaches employ the physiology of peripheral nerve injury to harness the regeneration of nerves to their *** review explores the underlying pathophysiology of neuroma formation and centralization of pain *** compares the traditional surgical approach for symptomatic neuroma resection and describes three novel surgical strategies that harness this pathophysiology of neuroma formation to their *** traditional resection of symptomatic neuromas is currently the standard of care for amputation patients,but new techniques including the regenerative peripheral nerve interface,targeted muscle reinnervation,and intraosseous transposition have shown promise in improving patient pain outcomes for postamputation pain and residual limb *** neuromas are a chronic and debilitating complication following amputation procedures and trauma,and the current standard of care does not address the underlying pathophysiology leading to the formation of the *** techniques are under development that may provide improved patient pain outcomes and a higher level of care for symptomatic neuroma resection.
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