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The cauchy problem for non-autonomous nonlinear Schr(o)dinger equations

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Science china Mathematics 2005年第4期48卷 522-538页

作者： peter Y. h. pang Department of Mathematics

In this paper we study the cauchy problem for cubic nonlinear Schr(o)dinger equation with space-and time-dependent coefficients on Rm and Tm. By an approximation argument we prove that for suitable initial values, the... 详细信息

关键词： non-autonomous Schr(o)dinger equations, local existence, global existence.

Ti-Zr-hf-Nb-Ta-Sn high-entropy alloys with good properties as potential biomaterials

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Rare Metals 2022年第7期41卷 2305-2315页

作者： Wei Yang Shu-Jie pang Guan Wang Ying Liu peter KLiaw Tao Zhang Key Laboratory of Aerospace Materials and Performance(Ministry of Education) School of Materials Science and EngineeringBeihang UniversityBeijing 100191China Beijing Advanced Innovation center for Biomedical Engineering Beihang UniversityBeijing 100191China AVIc Manufacturing Technology Institute Beijing 100024China Department of Materials Science and Engineering The University of TennesseeKnoxville TN 37996USA

(Ti_(0.2)Zr_(0.2)hf_(0.2)Nb_(0.2)Ta_(0.2))_(100-x)Sn_(x)(x=3,5,and 7;at%)high-entropy alloys(hEAs)with good mechanical properties,corrosion resistance,and biocompatibility were developed as potential *** effects of Sn additions on the microstructure and properties of the hEAs were ***(Ti_(0.2)Zr_(0.2)hf_(0.2)Nb_(0.2)Ta_(0.2))_(100-x)Sn_(x) with x=3 at%exhibited the single body-centered-cubic(Bcc)*** hEAs with the further increased Sn contents of x=5 at%and 7 at%were composed of a Bcc phase and a hexagonal-close-packed(hcP)-(Sn,Zr)ordered *** addition of Sn improved the compres-sive yield strengths and hardness of the hEAs to 1068-1259 MPa and hV 315-hV 390,*** hEAs also possessed relatively low Young's moduli of 80-91 *** the present Ti-Zr-hf-Nb-Ta-Sn hEAs,the(Ti_(0.2)Zr_(0.2)hf_(0.2)Nb_(0.2)Ta_(0.2))97Sn3 hEA exhibited the good combination of high yield strength of~1068 MPa,relatively low Young's modulus of 80 GPa,and good plasticity(~45%).The hEAs also possess good bio-corrosion resistance and biocompatibility,parallel to the Ti-6Al-4V *** Ti-Zr-hf-Nb-Ta-Sn hEAs with the integration of the high yield strength,relatively low Young's modulus,and good corrosion resistance and bio-compatibility are promising for biomedical applications.

关键词： high-entropy alloys Biomaterials Microstructure Mechanical properties corrosion Biocompatibility

FUNcTIONAL POLYhYDROXYALKANOATES SYNThESIZED BY MIcROORGANISMS

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chinese Journal of Polymer Science 2000年第5期18卷 389-396页

作者： peter h.Yu Open Laboratory of chiral Technology Hong Kong Polytechnic University Hong Kong China

Many bacteria have been found to synthesize a family of polyesters termed polyhydroxyalkanoate, abbreviated as PhA. Some interesting physical properties of PhAs such as piezoelectricity, non-linear optical activity, biocompatibility and biodegradability offer promising applications in areas such as degradable packaging, tissue engineering and drug delivery. Over 90 PhAs with various structure variations have been reported and the number is still increasing. The mechanical property of PhAs changes from brittle to flexible to elastic, depending on the side-chainlength of PhA. Many attempts have been made to produce PhAs as biodegradable plastics using various microorganisms obtained from screening natural environments, genetic engineering and mutation. Due to the high production cost, PhAs still can not compete with the nondegradable plastics, such as polyethylene and polypropylene. Various processes have been developed using low cost raw materials for fermentation and an inorganic extraction process for PhA purification. however, a super PhA production strain may play the most critical role for any large-scale PhA production. Our recent study showed that PhA synthesis is a common phenomenon among bacteria inhabiting various locations, especially oil-contaminated soils. This is very important for finding a suitable bacterial strain for PhA production. In fact, PhA production strains capable of rapid growth and rapid PhA synthesis on cheap molasses substrate have been found on molasses contaminated soils. A combination of novel properties and lower cost will allow easier commercialization of PhA for many applications.

关键词： polyhydroxybutyrate polyhydroxyalkanoate biopolymer polyester

Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis:a narrative review

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Neural Regeneration Research 2024年第4期19卷 747-753页

作者： peter h.King Department of Neurology and center for Neurodegeneration and Experimental Therapeutics The University of Alabama at BirminghamBirminghamALUSA Birmingham Veterans Affairs Medical center BirminghamALUSA

Amyotrophic lateral sclerosis is a fatal multisystemic neurodegenerative disease with motor neurons being a primary *** progressive weakness is a hallmark feature of amyotrophic lateral sclerosis,there is considerable heterogeneity,including clinical presentation,progression,and the underlying triggers for disease *** on longitudinal studies with families harboring amyotrophic lateral sclerosis-associated gene mutations,it has become apparent that overt disease is preceded by a prodromal phase,possibly in years,where compensatory mechanisms delay symptom *** 85-90%of amyotrophic lateral sclerosis is sporadic,there is a strong need for identifying biomarkers that can detect this prodromal phase as motor neurons have limited capacity for *** Food and Drug Administration-approved therapies work by slowing the degenerative process and are most effective early in the *** muscle,including the neuromuscular junction,manifests abnormalities at the earliest stages of the disease,before motor neuron loss,making it a promising source for identifying biomarkers of the prodromal *** accessibility of muscle through biopsy provides a lens into the distal motor system at earlier stages and in real *** advent of“omics”technology has led to the identification of numerous dysregulated molecules in amyotrophic lateral sclerosis muscle,ranging from coding and non-coding RNAs to proteins and *** technology has opened the door for identifying biomarkers of disease activity and providing insight into disease mechanisms.A major challenge is correlating the myriad of dysregulated molecules with clinical or histological progression and understanding their relevance to presymptomatic phases of *** are two major goals of this *** first is to summarize some of the biomarkers identified in human amyotrophic lateral sclerosis muscle that have a clinicopathological correlation with disease activi

关键词： amyotrophic lateral sclerosis biomarkers clinicopathological correlation disease progression muscle biomarkers neurogenic atrophy neuromuscular junction non-coding RNAs presymptomatic stages skeletal muscle SOD1G93A mouse model

Phytochrome-regulated Gene Expression

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Journal of Integrative Plant Biology 2007年第1期49卷 11-20页

作者： peter h. Quail Department of Plant and Microbial Biology University of Cafifomia Berkeley CA 94720 USA U.S. Department of Agriculture/Agriculture Research Service-Plant Gene Expression center 800 Buchanan Street Albany CA 94710 LISA

Identification of all genes involved in the phytochrome （phy）-medieted responses of plants to their light environment is an important goal in providing an overall understanding of light-regulated growth end development. This article highlights end integrates the central findings of two recent comprehensive studies in Arabidopsis that have identified the genome-wide set of phy-reguleted genes that respond rapidly to red-light signals upon first exposure of dark-grown seedlings, and have tested the functional relevance to normal seedling photomorphogenesis of an Initial subset of these genes. The data：（a） reveal considerable complexity in the channeling of the light signals through the different phy-femily members （phyA to phyE） to responsive genes; （b） identify a diversity of transcription-factor-encoding genes as major early, if not primary, targets of phy signaling, end, therefore, as potentially important regulators in the transcriptional-network hierarchy; and （c） identify auxin-related genes as the dominant class among rapidly-regulated, hormone-related genes. however, reverse-genetic functional profiling of a selected subset of these genes reveals that only a limited fraction are necessary for optimal phy-induced seedling deetioletion.

关键词： expression profiling phytochrome signaling transcriptional networks microarrays reverse genetics functional profiling transcription factors auxin-related genes

chapter 5 Study design

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维普期刊数据库

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实用休克杂志（中英文） 2019年第3期3卷 187-192页

作者： peter pang Yan chai hospital

Ⅰ Why do we need to conduct a study?·To fill in knowledge gap·To identify the good and the bad management·To find out new diagnostic methods·To prevent adverse outcome·To improve patient care FINER is the key co... 详细信息

关键词： pro chapter 5 Study design

chapter 7 with author note

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实用休克杂志（中英文） 2019年第5期3卷 315-320页

作者： peter pang Yan chai hospital

harm and PrognosisⅠ、harm articles aim at investigating any relationship of a harmful exposure and an adverse ***-control study only shows us an association.A well-designed cohort may demonstrate cause-effect *** we want to know whether smoking causes lung *** will be our study design?We cannot do a RcT to study *** will be unethical to randomize subjects into 2 groups:one group must smoke and another does *** can do a cohort study or case-control,*** study can be prospective or retrospective.

关键词： relationship. lung smoke

chapter 4 Meta-analysis on Therapy

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实用休克杂志（中英文） 2019年第2期3卷 123-128页

作者： peter pang Yan chai hospital

I . Narrative review vs. Systematic review Narrative review is a non-systematic review of a topic, after a comprehensive, critical and objective analysis of current literature. It is not required to list the types of databases and methodological approaches used, nor the evaluation criteria for inclusion of retrieved articles during databases search. These review articles use a qualitative approach. After full understanding of the topic viewed, you may then identify any knowledge gaps or inconsistencies. This will lead to a research question (PIcO) that justifies conducting further study.

关键词： Therapy Narrative review current literature

Effect of Ionic content in Semiconductive Shield Materials on Breakdown characteristics of Tree Retardant XLPE Power cable

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高电压技术 2010年第8期36卷 1912-1915页

作者： pang peter Miao Shawn Leung Simon Dow chemical (china) co. Ltd. Shanghai 201203 China Dow chemical Pacific co. Ltd. Hong Kong China

cable made with Dow hFDA-0587 BK,hFDB-4202 Ec, and hFDA-0693 BK was found to meet DL/T 1070-2007 requirement of tree retardant XLPE(TR-XLPE) power cable. The alternate-current breakdown(AcBD) value after 360 days of accelerated water treeing test(AWTT) was 29 kV/mm, which exceeds the DL/T 1070-2007 requirement of at least 20 kV/mm. cable made with semiconductive shield materials from other material suppliers and hFDB-4202 Ec, however, failed to meet DL/T 1070-2007 requirement of at least 20 kV/mm after 360 days of AWTT. This failure to meet DL/T 1070-2007 requirement, apparently, was caused by the high content of ionic contaminants and ash levels in the semiconductive shield materials. The results in this report suggest the use of clean semiconductive shield materials is necessary,in conjunction with tree retardant insulation material, for cables to meet the higher performance TR-XLPE DL/T 1070-2007 requirement, which will enhance system reliability by extending cable life, while lowering life cycle costs

关键词： TR-XLPE semiconductive shield DL/T 1070 ionic contamination Ac breakdown extend cable life