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Occurrence of Brachyoxylon Hollick et Jeffrey from the Lower Cretaceous of Zhejiang Province, southeastern China

Journal of Palaeogeography 2018年第4期7卷 316-325页

作者： Ning Tian zhi-peng zhu Yong-Dong Wang Si-Cong Wang college of palaeontology shenyang normal university Shenyang 110034Liaoning Province China state key laboratory of palaeobiology and stratigraphy nanjing institute of geology and palaeontologycas Nanjing 210008 Jiangsu Province China key laboratory of evolution of past life in northeast asia ministry of land and resources Shenyang 110034Liaoning Province China center for excellence in life and paleoenvironment chinese academy of sciencesnanjingjiangsu Province 110034 China

The Lower Cretaceous Guantou Formation is known as an important horizon for the Cretaceous petrified woods in southern China. Though abundant Cretaceous wood remains have been found in this formation, only one species has been recognized. A new coniferous wood, Brachyoxylon zhejiangense sp. nov. is described from the Lower Cretaceous Guantou Formation in Xinchang of Zhejiang Province, southeastern China. Anatomically, the new species is characterized by obscure annual rings, mixed type of radial pitting, araucarioid cross-field pits and uniseriate xylem rays. The finding of Brachyoxylon zhejiangense sp. nov. represents the first well-defined record of Brachyoxylon in southeastern China, and enriches the diversity of the Early Cretaceous petrified wood in southern China. Additionally, the new finding sheds new light on further understanding the floral composition, especially the forest vegetation type of the southern phytoprovince in the late Early Cretaceous. Diverse compressed leaf fossils of Cheirolepidiaceae have been described from the Guantou Formation in the fossil locality of the present petrified wood. The co-occurrence of Brachyoxylon zhejiangense sp. nov. and those cheirolepidiaceous leaf fossils provide additional evidences to support that Brachyoxylon may be systematically related to the Cheirolepidiaceae.

关键词： Brochyoxylon Cheirolepidiaceae Lower Cretaceous Guantou Formation Zhejiang Province

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Clinical analysis of multiple primary gastrointestinal malignant tumors:A 10-year case review of a single-center

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1204-1212页

作者： Cheng-Lou zhu Ling-zhi peng The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Surgical Oncology Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND Multiple primary malignant tumors(MPMTs)was first described by Billroth as early as 1889,with the first report published by Warren and Gates in *** then,numerous cases have been reported.A literature review of 1104269 patients with cancer revealed that the incidence of MPMTs ranged from 0.73 to 11.7%.In recent years,however,there has been a significant upward trend in the incidence of this phenomenon,which may be associated with many different factors,including the advancement of modern diagnostic procedures facilitating the examination and diagnosis of more MPMTs,increased exposure to chemotherapy and radiotherapy that exacerbate the risk of new malignant tumors in patients with cancer,and prolonged survival of patients with cancer allowing sufficient time for the development of new primary *** To analyze the incidence,clinical features,treatment factors,prevalence,and prognosis of patients with MPMTs in the gastrointestinal tract treated in a single ***,we analyzed the different tumor combinations,time interval between the occurrence of tumors,and *** This retrospective cohort study analyzed 8059 patients with pathologically confirmed gastrointestinal malignant tumors treated at the Gansu Province Hospital in Lanzhou,Gansu,China between June 2011 and June *** these,85 patients had *** clinical features,treatment factors,prevalence,and prognosis of this latter cohort were *** The incidence of MPMTs in patients with gastrointestinal malignant tumors was 1.05%(85/8059),including 83 double primary malignant tumors and two triple primary malignant tumors of which 57(67.06%)were synchronous MPMTs(SMPMTs)and 28(32.94%)were metachronous MPMTs(MMPMTs).The most frequent associations were found between the rectum colon cancers within the SMPMT category and the gastric-colon cancers within the MMPMT *** the MMPMTs,the median interval was 53 *** overall 1-,3-and 5-year survival rates f

关键词： Multiple primary malignant tumors Clinical characteristics Gastrointestinal tract Prognosis Epidemiology

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Stress-strain relationship for reactive powder concrete with recycled powder under uniaxial compression

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1015-1027页

作者： peng zhu Yunming zhu Wenjun QU Liyu XIE College of Civil Engineering Tongji UniversityShanghai 200092China Key Laboratory of Performance Evolution and Control for Engineering Structures of Ministry of Education Tongji UniversityShanghai 200092China

The recycled powder(RP)from construction wastes can be used to partially replace cement in the preparation of reactive powder *** this paper,reactive powder concrete mixtures with RP partially replacing cement,and natural sand instead of quartz,are *** curing is used,instead of steam curing that is normally requested by standard for reactive powder *** influences of RP replacement ratio(0%,10%,20%,30%),silica fume proportion(10%,15%,20%),and steel fiber proportion(0%,1%,2%)are *** effects of RP,silica fume,and steel fiber proportion on compressive strength,elastic modulus,and relative absorption energy are analyzed,and theoretical models for compressive strength,elastic modulus,and relative absorption energy are established.A constitutive model for the uniaxial compressive stress-strain relationship of reactive powder concrete with RP is *** the increase of RP replacement ratio from 0% to 30%,the compressive strength decreases by 42% and elastic modulus decreases by 24%.

关键词： recycled powder reactive powder concrete elastic modulus relative absorbed energy stress-strain relationship

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Edge and lithium concentration effects on intercalation kinetics for graphite anodes

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Journal of Energy Chemistry 2024年第3期90卷 337-347,I0009页

作者： Keming zhu Denis Kramer Chao peng School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048ShanxiChina Faculty of Mechanical Engineering Helmut-Schmidt UniversityHamburg 22043Germany School of Engineering University of SouthamptonSouthampton SO171BJUK Multiscale Crystal Materials Research Center Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055GuangdongChina

Graphite interfaces are an important part of the anode in lithium-ion batteries(LIBs),significantly influencing Li intercalation *** anodes adopt different stacking sequences depending on the concentration of the intercalated Li *** this work,we performed first-principles calculations to comprehensively address the energetics and dynamics of Li intercalation and Li vacancy diffusion near the no n-basal edges of graphite,namely the armchair and zigzag-edges,at high Li *** find that surface effects persist in stage-Ⅱ that bind Li strongly at the edge ***,the pronounced effect previously identified at the zigzag edge of pristine graphite is reduced in LiC_(12),penetrating only to the subsurface site,and eventually disappearing in LiC_(6).Consequently,the distinctive surface state at the zigzag edge significantly impacts and restrains the charging rate at the initial lithiation of graphite anodes,whilst diminishes with an increasing degree of *** diffusion time for Li hopping to the bulk site from either the zigzag edge or the armchair edge in LiC_(6) was observed during high state of charge due to charge *** controlling Li occupation and diffusion kinetics at this stage is also crucial for enhancing the charge rate.

关键词： Graphite anode Edge Interface Lithium-ion batteries Density functional theory

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Morphology of impact fragmentation distribution of single spherical and ellipsoidal particles in drop weight experiments

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Particuology 2024年第3期86卷 137-148页

作者： Qiuhua Miao peng Huang Wenchang zhu School of Mechanical Engineering Southeast UniversityNanjing211189China

Particle shape is an important factor affecting the fragmentation distribution of the ore *** investigate the influence of particle shape on the morphological fragmentation distribution characteristics,the crushable ore particles are defined as prolate,oblate ellipsoid and spherical particles,which have different aspect ratios(AR)and sphericity(S).Based on the drop weight experiment,the influence of the net drop height on the macroscopic mechanical behavior and crushing distribution characteristics of the single spherical and ellipsoidal particles is *** results show that different peak-shifting characteristics exist during particle *** fragmentation distribution peak shifts left when the increased impact energy is eventually only enough to break medium-sized ***,it shifts right when impact energy is increased enough to break largest-sized ***,regardless of whether the net drop height changes,the maximum continuous fragmentation degree presents"M"-shaped characteristic with the increased *** with the ellipsoid particles,the single spherical particle is more difficult to be broken by impact,with wider equivalent particle fragmentation *** the increase of particle sphericity,the maximum continuous fragmentation degree of a single ellipsoid particle has an overall trend of initial increase and subsequent *** when particle sphericity is 0.9

关键词： Ellipsoid particles Fragmentation distribution Drop weight experiment Numerical simulation

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edox factor-1 may mediate the repair of multiple organ injuries lfter fiver transplantation

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Chinese Medical Journal 2013年第13期 2504-2509页

作者： SUN zhi-peng zhu Yu-bing Aminbuhe GONG Ke zhu Bin FAN Qing LIAN Dong-bo ZHANG Neng-wei Department of General Surgery Beijing Shijitan Hospital Capital Medical University Beijing 100038 China

Background Apurinic apyrimidinic endonuclease/redox effector factor 1 （APE1/Ref-1） is an important enzyme in the repair of reactive oxygen species-induced DNA damage, and its expression/activation can be induced by reactive oxygen species. The aim of this research was to investigate the relationship between multiple-organ injuries and expression of Ref-1 in the early period after liver transplantation. Methods One hundred and fifty adult male Wistar rats were divided randomly into three groups： liver transplantation, sham surgery, and untreated control. After liver transplantation, animals were sacrificed at different time points. Hepatic and renal functions were analyzed by serology. Histology, apoptotic levels, and Ref-1 expression were examined by immunohistochemistry in the liver, kidneys, intestines, and lungs. Results Serum levels of alanine aminotransferase and aspartate aminotransferase peaked 6 hours after liver transplantation and decreased appreciably after 12 hours in the transplantatior~ group, suggesting that the degree of liver injury in the early period after transplantation peaked at 6 hours and then decreased. Pathological analyses showed that hepatic tissues were more severely injured in the transplantation group than in the sham and untreated groups. A considerable number of infiltrating inflammatory cells was observed around the portal vein in the transplantation group. Injuries to the kidneys, intestines, and lungs were milder after liver transplantation. Apoptotic levels increased after liver transplantation in all four organs examined. Ref-1 expression was higher in the transplantation group in the early period after liver transplantation than in the sham surgery and untreated control groups. Conclusion Ref-1 expression induced by ischemia-reperfusion injury may have a critical role in repairing multiple-organ injuries after liver transplantation.

关键词： liver transplantation, Ref-l multiple organ injury, apoptosis reactive oxygen species

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Growth process,defects,and dopants of bulkβ-Ga_(2)O_(3)semiconductor single crystals

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China Foundry 2024年第5期21卷 491-506页

作者： Yan-shen Wang Ming-zhi zhu Yuan Liu School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology(Ministry of Education) Beijing 100084China

β-gallium oxide(β-Ga2O3),as the typical representative of the fourth generation of semiconductors,has attracted increasing attention owing to its ultra-wide bandgap,superior optical properties,and excellent tolerance to high temperature and *** to the single crystals of other semiconductors,high-quality and large-sizeβ-Ga_(2)O_(3)single crystals can be grown with low-cost melting methods,making them highly *** this review,the growth process,defects,and dopants ofβ-Ga_(2)O_(3)are primarily ***,the growth process(e.g.,decomposition,crucible corrosion,spiral growth,and development)ofβ-Ga_(2)O_(3)single crystals are summarized and compared in ***,the defects ofβ-Ga_(2)O_(3)single crystals and the influence of defects on Schottky barrier diode(SBD)devices are emphatically ***,the influences of impurities and intrinsic defects on the electronic and optical properties ofβ-Ga_(2)O_(3)are also briefly *** this comprehensive analysis,the article offers a concise summary of the current state,challenges and prospects ofβ-Ga_(2)O_(3)single crystals.

关键词： β-Ga_(2)O_(3) single-crystal growth defects dopants semiconductor

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Advances in MET tyrosine kinase inhibitors in gastric cancer

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Cancer Biology & Medicine 2024年第6期21卷 484-498页

作者： Yifan Zhang Lin Shen zhi peng Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchDepartment of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China

Gastric cancer is among the most frequently occurring cancers and a leading cause of cancer-related deaths *** gastric cancer is highly heterogenous and comprised of different subtypes with distinct molecular and clinical characteristics,the management of gastric cancer calls for better-defined,biomarker-guided,molecular-based treatment *** is a receptor tyrosine kinase mediating important physiologic processes,such as embryogenesis,tissue regeneration,and wound ***,mounting evidence suggests that aberrant MET pathway activation contributes to tumour proliferation and metastasis in multiple cancer types,including gastric cancer,and is associated with poor patient *** such,MET-targeting therapies are being actively developed and promising progress has been demonstrated,especially with MET tyrosine kinase *** review aims to briefly introduce the role of MET alterations in gastric cancer and summarize in detail the current progress of MET tyrosine kinase inhibitors in this disease area with a focus on savolitinib,tepotinib,capmatinib,and *** on current knowledge,this review further discusses existing challenges in MET alterations testing,possible resistance mechanisms to MET inhibitors,and future directions of MET-targeting therapies.

关键词： Gastric cancer MET alterations MET tyrosine kinase inhibitors savolitinib MET testing

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Neoadjuvant Chemoradiotherapy Improving Survival Outcomes for Esophageal Carcinoma： An Updated Meta-analysis

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Chinese Medical Journal 2016年第24期129卷 2974-2982页

作者： Dong-Bin Wang Zhong-Yi Sun Li-Min Deng De-Qing zhu Hong-Gang Xia peng-zhi zhu Department of Cardiothoracic Surgery Tianjin Hospital Tianjin 300211 China

Background： The effectiveness of neoadjuvant chemoradiotherapy （NCRT） treatment for patients with esophageal carcinoma （EC） remains controversial. The aim of this study was to compare the effect of NCRT followed by surgery （NCRTS） with surgery alone （SA） for EC. Methods： The PubMed, EMBASE, and the Cochrane Library databases were electronically searched up to August 2015 for all the published studies that investigated EC patients receiving either NCRTS or SA, and the reference lists were also manually examined for the eligible studies. The risk ratio （RR） with 95% confidence intervals （CI s） as effective size was determined to assess the 1-, 3-, 5-year survival rates （SRs）, postoperative morbidity, and postoperative mortality. Heterogeneity was determined using the Q-test. The Begg＇s test and Egger＇s test were used for assessing any potential publication bias. Results： Of 1120 identified studies, 16 eligible studies were included in this analysis （involving 2549 patients）. Overall, the pooled results suggested that NCRTS was associated with significantly improved 1-year （RR： 1.07, 95% CI： 1.02–1.13）, 3-year （RR： 1.26, 95% CI： 1.14–1.39）, and 5-year （RR： 1.36, 95% CI： 1.18–1.56） SRs. However, the results also indicated that NCRTS had no or little effect on postoperative morbidity （RR： 0.93, 95% CI： 0.82–1.05） and postoperative mortality （RR： 1.17, 95% CI： 0.56–2.44）. Conclusions： Compared with SA, NCRTS can increase 1-, 3-, and 5-year SRs in patients with EC.

关键词： Esophageal Carcinoma Meta-analysis Neoadjuvant Chemoradiotherapy Survival Outcomes

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Terminal attitude selection method of missile attack aircraft

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Chinese Journal of Aeronautics 2024年第2期37卷 385-400页

作者： peng HOU Yang PEI Yuxue GE Mengjie zhu School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China Research Department Shanghai Electro-Mechanical Engineering InstituteShanghai 201108China

The appropriate terminal attitude of missile is important to improve the damage effectiveness of fragmentation warhead against aircraft *** this paper,three missile terminal attitude selection methods are proposed to solve the problem of terminal attitude selection in different situations according to their respective evaluation *** MVE-based method uses the damage probability of each detonation point around the aircraft at a given attitude of missile to calculate the Mean Volume of Effectiveness(MVE)at the corresponding attitude,and then uses the MVE for different attitudes to select the terminal strike *** detonation position-based method addresses the case where the missile detonation position can be assessed in *** the effects of missile guidance errors and fuze activation position errors,Monte Carlo simulations are used to calculate the damage probability of aircraft with different strike attitudes,from which the terminal strike attitude is *** BP-ANN model-based method uses the constructed Back Propagation Artificial Neural Network(BP-ANN)model instead of simulation to calculate the evaluation indexes in the corresponding cases of MVE-based method and Detonation position-based method,which can improve the efficiency of attitude *** are conducted for different scenarios to verify the feasibility and effectiveness of the proposed method.

关键词： Aircraft vulnerability Attitude selection BP-ANN Damage probability Damage effectiveness

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