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Development of lamellar gel phase emulsion containing baru oil(Dipteryx alata Vog.) as a prospective delivery system for cutaneous application

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Asian Journal of Pharmaceutical Sciences 2018年第2期13卷 183-190页

作者： Cristhianne Moraes Jorge L.V.Anjos Monica Maruno Antonio Alonso pedro Rocha-Filho Department of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences of Ribeirão PretoUniversidade de São PauloRibeirão Preto 14040-903SPBrazil Physics Department Universidade Federal de Goiás(UFG)Campus Catalão-Av.Dr.Lamartine Pinto de Velar1120St.Universitário75704-020Catalão-GOBrazil Pharmacy Course Coordination Centro Uni.Barão de MauáR.Ramos de Azevedo423Jardim PaulistaRibeirão PretoSP 14090-180Brazil Biophysics Laboratory Physics InstituteUniversidade Federal de Goiás(UFG)Goiânia 74.690-900GOBrazil

The rational design of emulsions requires study of the main factors that influence their formation, physicochemical properties and, consequently, stability and performance. The use of vegetable oils in the pharmaceutical and cosmetic industries has recently become attractive. Dipteryx alata Vogel(D. alata) is an oleaginous species native to Brazil. The seeds of this species contain highly unsaturated oil with significant amounts of tocopherols and phytosterols, representing an important source of agents capable of combatting oxidative processes. In this work, a lamellar gel phase emulsion using oil extracted from the seeds of D. alata(baru) was developed. The steps involved in the development of this research were as follows: 1) development of formulations and 2) in vitro assays by simulating the evaporation of the final product after application to the skin and Electron paramagnetic resonance spectroscopy(EPR) of fatty acid spin labels was used to investigate the profile of interaction of the dispersed systems with stratum corneum(SC) lipids. The results indicate that the developed system shows no signs of instability during the storage period. Moreover, EPR studies indicated that D. alata oil and especially the developed formulation were able to increase SC lipid fluidity and extract a fatty-acid spin label from the lipid domain structures of SC, demonstrating its potential to act as a drug or skin care vehicle.

关键词： Stratum corneum O/W emulsions Baru oil EPR spectroscopy

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Impact of Cluster Thinning on Quality of“Malbec”Grapes in Encruzilhada do Sul-RS

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American Journal of Plant Sciences 2018年第3期9卷 495-506页

作者： Maria Inez Lopes Fernandes de barros Dianini Brum Frolech Letícia Leal de Mello Roberta Manica-Berto Marcelo Barbosa Malgarim Vagner Brasil Costa paulo Mello-Farias Departamento de Fitotecnia Universidade Federal de PelotasPelotasBrazil Tríade-Comunicacao Científica PelotasBrazil Universidade Federal do Pampa Campus Dom PedritoDom PedritoBrazil

The cultivar Malbec has been present’s good performance and quality in the South Half of Rio Grande do Sul (RS). In this context, we aimed to evaluate the quality of “Malbec” grapes in relation to the phytotechnical, physicochemical parameters and bioactive compounds under different intensities of cluster thinning in Encruzilhada do Sul-RS. The experiment was carried out in a commercial vineyard in the 2015/16 with the cultivar Malbec (Vitis vinifera L.) under rootstock “1103 Paulsen”, with spacing of 2.2 m between rows and 1.1 m between plants. The experimental design was of randomized complete blocks with five replications. The treatment factor tested was the cluster thinning, with four levels (0%, 10%, 30% and 50%), performed in véraison. The evaluated phytotechnical variables were cluster length, cluster fresh weight, berries fresh weight, number of berries, rachis fresh weight. Also what were determined are the number of clusters, production and Ravaz index. The physicochemical variables verified were pH, soluble solids (SS), titratable acidity (TA) and SS/TA ratio. The bioactive compounds were total polyphenols index and total anthocyanins. The appropriate balance between source and sink, by the Ravaz index, occurs to zero and 10% of cluster thinning. The “Malbec” grapes present an increase of the maturation index (SS/TA) at 50% of cluster thinning, due to the low titratable acidity at this level. The total polyphenols index has a larger increment when the plants are submitted to the cluster thinning of 10%, providing a larger quality to the fruits. At all the levels of cluster thinning tested, when compared to the control, there was a greater contribution of total anthocyanins in the berries.

关键词： Vitis vinifera Maturation Index Bioactive Compounds Ravaz Index Polyphenols

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LAND-USE INTENSIFICATION TRENDS IN THE RIO DE LA PLATA REGION OF SOUTH AMERICA:TOWARD SPECIALIZATION OR RECOUPLING CROP AND LIVESTOCK PRODUCTION

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Frontiers of Agricultural Science and Engineering 2021年第1期8卷 97-110页

作者： paulo César DE FACCIO CARVALHO Jean Víctor SAVIAN Tomas DELLA CHIESA William DE SOUZA FILHO JoséAlfredo TERRA Priscila PINTO Amanda POSSELT MARTINS Sebastian VILLARINO Júlio Kuhn DA TRINDADE pedro Arthur DE ALBUQUERQUE NUNES Gervasio PIÑEIRO Integrated Crop-Livestock Systems Research Group Federal University of Rio Grande do Sul7712 Bento Gonçalves AvenuePorto Alegre RS 91540-000Brazil Instituto Nacional de Investigación Agropecuaria(INIA) Estación Experimental INIA Treinta y TresRuta 8 km 281Treinta y TresUruguay Facultad de Agronomía Universidad de Buenos AiresIFEVA/CONICETArgentina Unidad Integrada Balcarce Facultad de Ciencias AgrariasUniversidad Nacional de Mar del Plata(UNMdP)Estación Experimental Agropecuaria Balcarce(INTA)Argentina Department of Agricultural Research and Diagnosis Secretariat of AgricultureLivestock and Rural Development of Rio Grande do Sul Facultad de Agronomía Universidad de la RepúblicaUruguay

The Rio de la Plata region comprises central Argentina,Uruguay,and southern *** agriculture developed around 1900 with recent decades being characterized by the advance of cropping areas over native *** specialized agriculture has decoupled crop and livestock production but has succeeded in intensifying ***,significant losses of ecosystem services have been ***,questions have been raised on the sustainability of this pathway.A glance at world regions that have experienced similar trends suggests that an urgent course correction is needed.A major concern has been the lack of diversity in regions with highly specialized agriculture,promoting renewed interest in integrated crop-livestock systems(ICLS),not only because ICLS are more diverse than specialized systems,but also because they are rare examples of reconciliation between agroecosystem intensification and environmental ***,this paper discusses alternatives to redesign multifunctional landscapes based on *** data provide evidence that recoupling crop and animal production increases the resilience of nutrient cycling functions and economic indicators to external stressors,enabling these systems to face climate-market uncertainty and reconcile food production with the provision of diverse ecosystem ***,these concepts are exemplified in case studies where this perspective has been successfully applied.

关键词： grazing integrated crop-livestock systems mixed crops-livestock Pampa

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Effect of increasing densities of Urochloa brizantha cv. Marandu on Eucalyptus urograndis initial development in silvopastoral system

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Journal of Forestry Research 2019年第2期30卷 537-543页

作者： Michel Anderson Almeida Colmanetti Allan Lopes Bacha pedro Luis da Costa Aguiar Alves Rinaldo Cesar de Paula University of Sao paulo – USP/ESALQ Sao paulo State University – UNESP/FCAV

In silvopasture system, the coexistence of eucalyptus seedlings with other species may result in growth reduction, especially during eucalyptus early ***, studies elucidating how forage species affect the eucalyptus growth can provide important information for their rational management aiming to obtain the maximum gain of the system. The aim of this work was to evaluate the effect of increasing densities of Urochloa brizantha *** in the early development of Eucalyptus urograndis. An experiment was conducted in 20 L pots, in an open and semi-controlled area, during 90 days after planting of eucalyptus. A completely randomized design with four replications was used, in a 6 9 7 factorial system, meaning six evaluation periods and seven densities of U. brizantha: 0(control), 22, 33, 44, 67, 89 and111 plants m^(-2). Fortnightly, eucalyptus height, stem diameter and chlorophyll fluorescence(Fv/Fm) were evaluated. At the end of experimental period, the net assimilation rate, stomatal conductance and transpiration rate of eucalyptus plants were determined, in addition to the dry matter of eucalyptus(leaves and stem) and U. brizantha (leaves). In coexistence with 111 plants m^(-2), eucalyptus had reduction of 63.9% on total dry matter and 72.7% on leaf area, compared to the control. From the density of22 plants m^(-2), U. brizantha negatively interfere significantly the growth of E. urograndis. Up to 8 plants m^(-2) there are no reductions greater than 5% in eucalyptus height and stem diameter.

关键词： Eucalyptus Palisade grass Competition Interference

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A Parallel Approach for Real-Time Power Flow in Distribution Networks

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Journal of Energy and Power Engineering 2013年第3期7卷 589-595页

作者： Rafael G. Milbradt Luciane N. Canha pedro B. Zorrilla Alzenira R. Abaide paulo R. Pereira Sandro R.Schmaedecke Centre of Studies in Energy and Power Systems Federal University of Santa Maria Santa Maria 97105-900 Brazil State Company of Electric Power Distribution of Rio Grande do Sul Porto Alegre 91410-900 Brazil

The new reality of smart distribution systems with use of generation sources of small and medium sizes brings new challenges for the operation of these systems. The complexity and the large number of nodes requires use of methods which can reduce the processing time of algorithms such as power flow, allowing its use in real time. This paper presents a known methodology for calculating the power flow in three phases using backward/forward sweep method, and also considering other network elements such as voltage regulators, shunt capacitors and sources of dispersed generation of types PV （active power and voltage） and PQ （active and reactive power）. After that, new elements are introduced that allow the parallelization of this algorithm and an adequate distribution of work between the available processors. The algorithm was implemented using a multi-tiered architecture; the processing times were measured in many network configurations and compared with the same algorithm in the serial version.

关键词： Distribution power flow real-time power flow distribution automation dispersed generation parallel algorithm.

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Assessment of Model Predictive Control Performance Criteria

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Journal of Chemistry and Chemical Engineering 2015年第2期9卷 127-135页

作者： Rafael Lopes Duarte-barros Song Won Park Emerson Process Management Rio de Janeiro 20. 090-003 Brazil Department of Chemical Engineering University of Sao Paulo Sao Paulo 05424-970 Brazil

The current highly competitive environment has driven industries to operate with increasingly restricted profit margins. Thus, it is imperative to optimize production processes. Faced with this scenario, multivariable predictive control of processes has been presented as a powerful alternative to achieve these goals. Moreover, the rationale for implementation of advanced control and subsequent analysis of its post-match performance also focus on the benefits that this tool brings to the plant. It is therefore essential to establish a methodology for analysis, based on clear and measurable criteria. Currently, there are different methodologies available in the market to assist with such analysis. These tools can have a quantitative or qualitative focus. The aim of this study is to evaluate three of the best current main performance assessment technologies： Minimum Variance Control-Harris Index; Statistical Process Control （Cp and Cpk）; and the Qin and Yu Index. These indexes were studied for an alumina plant controlled by three MPC （model predictive control） algorithms （GPC （generalized predictive control）, RMPCT （robust multivariable predictive control technology） and ESSMPC （extended state space model predictive controller）） with different results.

关键词： Predictive controller performance minimum variance capability MPC GPC ESSMPC (extended state space model predictive controller).

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Philosophy and Fiction Tattoo of the Counter-culture Crossing the Brazilian Dictatorship

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Journalism and Mass Communication 2014年第9期4卷 565-571页

作者： Marcus Pereira Novaes Luciano Victor barros Maluly University of Campinas Campinas Brazil University of Sao paulo Sao Paulo Brazil

This paper seeks to explore connections between some philosophical concepts and the movie Tattoo （Brazil, 2013）, directed by Hilton Lacerda. This movie approaches the Slash movies, a kind of Brazilian movies that use the humor and the mockery as ways of resistance to interrogate political, philosophical, and moral questions. The concepts of fabulation and the potency of the false will be thought in its connections with the Arts to think the force of this movie with its experimental characteristics （sound, image, performance...） in touching ethics, political, and social problems of the past and update them to think the Brazilian contemporary society. We also want to point out the possibilities of this movie operating a micro-political resistance, using the humor and irony as tools to cause effects in the reality. In Tattoo, the violence （and, the oppression itself） is fought by the tasting and experimentation of another culture providing other ways of life, enabling other effectuations and desires, even if the sanction was going to repress.

关键词： philosophy of difference cinema fabulation irony resistance

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Mechanobiology of the cell surface:Probing its remodeling dynamics using membrane tether pulling assays with optical tweezers

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BIOCELL 2022年第9期46卷 2009-2013页

作者： JULIANA SOARES DOUGLAS G.FREITAS pedro S.LOURENÇO JEFTE FARIAS BRUNO PONTES Centro Nacional de Biologia Estrutural e Bioimagem-CENABIO Universidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação em Ciências Biológicas Biofísica Instituto de Biofísica Carlos Chagas FilhoUniversidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação Multidisciplinar em Física Aplicada Instituto de FísicaUniversidade Federal do Rio de JaneiroRio de Janeiro21941-972Brazil Instituto de Ciências Biomédicas Universidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação em Biotecnologia Instituto de Ciências BiológicasUniversidade Federal do AmazonasManaus69067-005Brazil

Mammalian cell surfaces consist of the plasma membrane supported by an underneath cortical ***,these structures can control not only the shape of cells but also a series of cellular functions ranging from migration and division to exocytosis,endocytosis and ***,the cell surface is capable of exerting and reacting to mechanical *** viscoelastic properties,especially membrane tension and bending modulus,are fundamental parameters involved in these *** viewpoint summarizes our current knowledge on how to measure the viscoelastic properties of cell surfaces employing optical tweezers-based tether assays,paving the way for a better understanding of how cells react to external mechanical forces,with a glance on their remodeling dynamics and possible consequences on downstream cellular processes.

关键词： Cell surface architecture Actin cortex Membrane-cytoskeleton complex Optical tweezers Tether extraction

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Does landscape context affect pollinationrelated functional diversity and richness of understory flowers in forest fragments of Atlantic Rainforest in southeastern Brazil?

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Ecological Processes 2020年第1期9卷 737-748页

作者： Karoline Baptista de Lima Patrícia Alves Ferreira Milton Groppo Renato Goldenberg Emerson Ricardo Pansarin Roxana Cardoso Barreto Guilherme Peres Coelho Yago barros-Souza Danilo Boscolo Biology Department Faculty of PhilosophySciences and LettersUniversity of São PauloRibeirão PretoSP 14040-901Brazil National Institute of Science and Technology in Interdisciplinary and Transdisciplinary Studies in Ecology and Evolution(IN-TREE) SalvadorBrazil Botany Department Biological Science SectorParanáFederal UniversityCuritibaPR 81531-970Brazil Botany Department Biological Science CenterPernambuco Federal UniversityRecifePE 50670-420Brazil Institute of Bioscience Rio Grande do Sul Federal UniversityPorto AlegreRS 90040-060Brazil Botany Department Federal University of São CarlosSão CarlosSP 13565-905Brazil.

Background:How landscape modifications affect functional diversity of floral characteristics pertinent to pollinators is poorly *** possess functional traits that sometimes coevolved with pollinators,crucial for the maintenance of both pollinator and plant *** evaluated how richness and functional diversity of available understory flowers respond to forest cover and landscape heterogeneity in a multiscale *** in bloom were sampled from 25 landscapes in the understory of Atlantic Forest fragments in *** were classified into functional groups regarding flower characteristics relevant to *** heterogeneity and forest cover were measured in buffers ranging from 200 to 2000 m from sampling units and their correlation with plant richness and functional diversity was assessed using generalized linear models and further model selection through Akaike’s second-order information ***:Plants’richness and functional diversity were affected negatively by forest *** former responded to forest cover at a regional scale while the latter responded at a local *** landscape heterogeneity increased richness and functional ***:Our results showed that forest cover and landscape heterogeneity are important to support biodiversity related to pollination,mostly due to the availability of diversified resources and nesting sites associated to different land-uses for pollinators and flowering plant *** findings should highlight,along with forest cover,landscape heterogeneity as an environmental management priority in rural tropical areas for mitigating the loss of plant biodiversity and enhancing ecosystem functioning.

关键词： Functional diversity Pollination Landscape heterogeneity Forest cover Understory plant community

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What a few hairs can tell us about the resource use of giant armadillos

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Integrative Zoology 2023年第1期18卷 129-142页

作者： Marcelo MAGIOLI Nina ATTIAS Gabriel MASSOCATO Danilo KLUYBER Marcelo Zacharias MOREIRA Katia Maria Paschoaletto Micchi de barros FERRAZ Adriano Garcia CHIARELLO Arnaud L.J.DESBIEZ Instituto Pró-Carnívoros AtibaiaSão PauloBrazil Centro Nacional de Pesquisa e Conservação de Mamíferos Carnívoros(CENAP) Instituto Chico Mendes de Conservação da Biodiversidade(ICMBio)AtibaiaSão PauloBrazil Instituto de Conservação de Animais Silvestres(ICAS) Campo GrandeMato Grosso do SulBrazil Instituto de Pesquisas Ecológicas Organização Não GovernamentalNazaréPaulistaSão PauloBrazil Houston Zoo HoustonTexasUSA Naples Zoo at Caribbean Gardens NaplesFloridaUSA Laboratório de Ecologia Isotópica Centro de Energia Nuclear na AgriculturaUniversidade de São PauloPiracicabaSão PauloBrazil Laboratório de Ecologia Manejo e Conservação de Fauna Silvestre(LEMaC)Departamento de Ciências FlorestaisEscola Superior de Agricultura“Luiz de Queiroz”(ESALQ)Universidade de São Paulo(USP)PiracicabaSão PauloBrazil Departamento de Biologia Faculdade de FilosofiaCiências e LetrasUniversidade de São Paulo(USP)Ribeirão PretoSão PauloBrazil RZSS-Royal Zoological Society of Scotland(RZSS) MurrayfieldEdinburghUK

Understanding of resource requirements of vulnerable species is key for conservation ***,we used sta-ble carbon(δ13C)and nitrogen isotopes(δ15N)of hair from giant armadillos(Priodontes maximus)to understand individual resource *** collected hair from 19 giant armadillos analyzing 34 samples from the Brazilian Pan-tanal and compared the resource use between sexes and age *** also assessed the relationship of isotopic values with individuals’body mass and the habitat type *** observed a wide variation in resource use by giant armadillos,showing that individuals consume prey that feeds on distinct resources and occupies different habitat types,indicating that there is individual variation in foraging *** giant armadillos presented a mixed diet(C3/C4 resources,forests/open areas),but a quarter of individuals had strictly C4 diets(open areas).Males are more prone to forage on C4 resources,presenting an isotopic niche 2.6-times larger than that of *** presented diets more associated with habitats with high arboreal cover(C3 resources,forests),while adults foraged more in open areas(C4 resources).This result is mirrored by the positive relationship betweenδ13C values and body mass,suggesting that larger giant armadillos tend to feed more in open *** observed thatδ13C values decreased as individuals increased the use of habitats with high arboreal *** stress the importance of con-serving the natural mosaic in the Pantanal landscape for the species persistence,given that giant armadillos require all habitat types to fulﬁll their dietary,spatial,and developmental needs.

关键词： diet ontogenetic changes resource partitioning stable isotopes telemetry

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