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Comparing K-Means and Mean Shift Algorithms Performance Using Mahout in a Private Cloud Environment

通讯和计算机（中英文版） 2014年第1期11卷 45-51页

作者： paulo muniz de avila Roan Simoes da Silva Luiz Angelo Valota Francisco Rodrigo Palucci Pantoni David Buzatto Sergio Donizetti Zorzo department oflnformatics Federal Institute of South of Minas Gerais (IFSULDEMINAS) Minas Gerais 13872-551 Brazil department of lnformatics Federal Institute of Sao Paulo (IFSP) Sao Paulo O1109-010 Brazil Computing department Federal University of Sao Carlos (UFSCar) Sao Paulo 13565-905 Brazil

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Periodontal research contributions to basic sciences:From cell communication and host-parasite interactions to inflammation and bone biology

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BIOCELL 2022年第3期46卷 633-638页

作者： RAFAEL SCAF de MOLON ERICA DORIGATTI de avila JONI AUGUSTO CIRELLI JOAO paulo STEFFENS Federal University of Rio de Janeiro-UFRJ Rio de Janeiro21941-617Brazil São paulo State University-UNESP Araraquara14801-930Brazil Federal University of Parana-UFPR Curitiba80210-170Brazil

The periodontium comprises all structures surrounding the teeth,including gingiva,root cementum,periodontal ligament and alveolar *** tissues aim to protect and support the teeth and are challenged by a residing microbiota that leads to subclinical inflammation even in physiological ***,a prevalent multicausal inflammatory and destructive disease,develops as a result from complex host-parasite *** unique physiologic and pathologic scenario enables the development of research methods which allows conclusions beyond the simple understanding of periodontal *** aim of this viewpoint was to explore potential contributions of periodontal research to a wide array of basic science specialties,such as cell and molecular biology,microbiology,immunology,endocrinology,rheumatology,among others.

关键词： Alveolar bone Bone Periodontal disease Rheumatoid arthritis

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Partitioning between primary and secondary metabolism of carbon allocated to roots in four maize genotypes under water deficit and its effects on productivity

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The Crop Journal 2015年第5期3卷 379-386页

作者： Alyne Oliveira Lavinsky paulo Cesar Magalhaes Roniel Geraldo avila Mariana Melo Diniz Thiago Correa de Souza Embrapa Milho e Sorgo Sete LagoasMGCEP:35701-970Brazil Universidade Federal de Lavras LavrasMGCEP 37200-000Brazil Universidade Federal de Sao Joao del Rey Sete LagoasMGCEP 35701-970Brazil Universidade Federal de Alfenas AlfenasMGCEP 37130-000Brazil

Plants may respond to drought by altering biomass allocation to shoots and roots or by changing the metabolic activities in these organs. To determine how drought changes the partitioning of carbon allocated to growth and secondary metabolism in maize roots and how it affects photosynthesis(A) and productivity in maize, we evaluated leaf gas exchange, yield componentes, root morphology, and primary and secondary metabolites including total soluble sugars(TSS), starch(S), phenolics(PHE), and lignin(LIG). Data were collected from pot-grown plants of four maize genotypes: BRS 1010 and 2B710(sensitive genotypes) and DKB390 and BRS1055(tolerant genotypes) under two soil water tensions: field capacity(FC,-18 kP a) and water deficit(WD,-138 kP a). WD was applied at the pre-flowering stage for 12 days and then the water supply was restored and maintained at optimum levels until the end of the cycle. For genotype BRS 1055 under FC, the greatest A did not result in greater grain biomass(DGB) because the accumulated photoassimilates had already filled the cells, and thus the excessive TSS synthesized in leaves was allocated to roots in large amounts. However, the sharp decrease in A caused by WD imposition in this genotype did not affect the influx pressure of leaf TSS, which was due largely to conversion of primary metabolites to PHE compounds to increase the length of fine roots. In leaves of DKB390 under WD, both S and TSS were reduced, whereas PHE were increased to prevent excessive water loss and xylem cavitation. Under WD, both BRS1010 and2B710 genotypes displayed reduced allocation of biomass to shoots and roots and LIG content in leaves, as well as lower A and DGB values. In BRS1010 this response was coupled to S decrease in leaves and TSS increase in roots, whereas in 2B710 there was a concomitant S increase in roots.

关键词： Starch Sugars Lignin Phenols WinRHIZO

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Implant surface features as key role on cell behavior

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BIOCELL 2022年第5期46卷 1151-1156页

作者： RAFAEL SCAF de MOLON MARTA MARIA ALVES PEREIRA ERICA DORIGATTI de avila Federal University of Rio de Janeiro Rio de Janeiro21941-617Brazil São paulo State University Araraquara14801-930Brazil

It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix(ECM)that may affect cell *** nature,ECM is a heterogeneous three-dimensional superstructure formed by three major components,glycosaminoglycan,glycoconjugate,and protein,that anchors cellular compartments in tissues and regulates the function and the behavior of *** in the biointerface alter the quality of ECM and morphology through cell surface receptors,which,in turn,enable it to trigger specific cell signaling and different cellular *** fact,a number of strategies have been used to improve the functionality of surfaces and direct cell behavior through precisely designed ***,we aimed to discuss,through a science-based viewpoint,the biomaterial surface features on cell behavior and analyze the impact of cell physical modification on dental implant development.

关键词： Biomaterial Cell adhesion Surface chemistry Surface topography

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Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice

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Neural Regeneration Research 2022年第2期17卷 450-458页

作者： Carlos Pereira Martins Rodrigo Sebben Paes Gabriela Mantovani Baldasso Eduarda Gomes Ferrarini Rahisa Scussel Rubya Pereira Zaccaron Ricardo Andrez Machado-de-avila paulo Cesar Lock Silveira Rafael Cypriano Dutra Laboratory of Autoimmunity and Immunopharmacology Department of Health SciencesCampus AraranguaUniversidade Federal de Santa CatarinaAraranguáSCBrazil Post-Graduate Program of Neuroscience Center of Biological SciencesUniversidade Federal de Santa CatarinaFlorianópolisSCBrazil Laboratory of Experimental Physiopathology Program of Postgraduate in Science of HealthUniversidade do Extremo Sul CatarinenseCriciumaSCBrazil

Fibromyalgia(FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still unknown, a significant decrease in biogenic amines is a common characteristic in its pathogenesis. Here, our main objective was to investigate the role of dopamine D3/D2 receptor during the reserpine-induced pain in mice. Our results showed that pramipexole(PPX) – a dopaminergic D3/D2 receptor agonist – inhibited mechanical allodynia and thermal sensitivity induced by reserpine. Relevantly, PPX treatment decreased immobility time and increased the number of grooming in the forced swimming test and splash test, respectively. Animals that received PPX remained longer in the open arms than the reserpine group using elevated plusmaze apparatus. The repeated PPX administration, given daily for 4 days, significantly blocked the mechanical and thermal allodynia during FM model, similarly to pregabalin, although it failed to affect the reserpine-induced thermal nociception. Reserpine administration induced significant downregulation of dopamine concentration in the central nervous system, and repeated treatment with PPX restored dopamine levels in the frontal cortex and spinal cord tissues. Moreover, PPX treatment inhibited oxidants production such as DCFH(2′,7′-dichlorodihydrofluorescein) and nitrite, also decreased oxidative damage(carbonyl), and upregulated the activity of superoxide dismutase in the spinal cord. Together, our findings demonstrated the ability of dopamine D3/D2 receptor-preferring agonist in reducing pain and mood dysfunction allied to FM in mice. All experimental protocols were approved by the Universidade Federal de Santa Catarina(UFSC) Ethics Committee(approval No. 2572210218) on May 10, 2018.

关键词： dopamine dopaminergic system fibromyalgia hyperalgesia pain pramipexole reserpine

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Clinical outcomes after implantation of a new intrastromal corneal ring with 140-degree of arc in patients with corneal ectasia

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 802-806页

作者： Jordana Sandes Larissa R.S.Stival Marcos Pereira de avila paulo Ferrara Guilherme Ferrara Leopoldo Magacho Luana P.N.Araujo Leonardo Torquetti Center of Reference in Ophthalmology (CEROF) Goiania 64605-020 Brazil paulo Ferrara Eye Clinic Belo Horizonte-MG 30110-921 Brazil Fundacao Altino Ventura Recife-PE 50070-040 Brazil Center of Excellence in Ophthalmology Para de Minas35660-017 Brazil

AIM：To evaluate the clinical and tomographic outcomes after implantation of a new intrastromal corneal ring segment（ICRS） with 140-degrees of arc in eyes with corneal ***：We evaluated patients with corneal ectasia implanted with Ferrara 140° ICRS from April 2010 to February *** measures included preoperative and postoperative corrected distance visual acuity（CDVA）,keratometry simulated（K） reading,tomographic astigmatism and *** patients were evaluated using the Pentacam Scheimpflug ***：The study evaluated 58 *** mean followup was 16.81±10.8 *** CDVA（logM AR） improved from 0.5±0.20（20/60） to 0.3±0.21（20/40）（P〈0.01）.The average K reduced from 49.87±7.01 to 47.34±4.90 D（P〈0.01）.The asphericity changed from-0.60±0.86 to-0.23±0.67 D（P〈0.01）.The mean preoperative tomographic astigmatism decreased from-8.0±3.45 to-4.53±2.52 D（P〈0.01）.CONCLUSION：The new ICRS model with 140-degrees of arc effectively improve the visual acuity and reduce the high astigmatism usually found in patients with corneal ectasia.

关键词： keratoconus intrastromal corneal ring segment corneal ectasia

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Dynamical Outlines of the Rainfall Variability and the ITCZ Role over the West Sahel

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Atmospheric and Climate Sciences 2012年第3期2卷 337-350页

作者： paulo Sergio Lucio Luiz Carlos Baldicero Molion Cati Elisa de avila Valadao Fabio Cunha Conde Andrea Malheiro Ramos Maria Luciene Dias de Melo Centro de Geofisica de Evora(CGE) EvoraPortugal Universidade Federal do Rio Grande do Norte(UFRN) Centro de Ciencias Exatas e da Terra(CCET)NatalBrazil Universidade Federal de Alagoas(UFAL) AlagoasBrazil Instituto Nacional de Meteorologia(INMET) BrasíliaBrazil

This article evaluated the plausible causes of floods and droughts, the relative roles of large-scale climate variability in regional environmental trends, and the prospects for the future of the semiarid Sahel region in the context of periodic climate change. It is pointed out that the most significant rainfall climatological changes in the Sahel probably occurred between 1950 and 1980 with the decrease of the annual rainfall, a very high deficit (about 70%) over the whole region. The last three decades considered in this research (1981-2010) showed some improvement. The more humid conditions were from the last decade 2001 to 2010. One of the most significant climatic variations has been the persistent rainfall decline in the Sahel since late 1960s. Remarkable latitudinal shift of ITF mean position towards the South generated an overall reduction of annual rainfall. Basically, in this manuscript one analyzes the dynamical features on rainfall time series and the association of the cyclic periods with teleconnections under the hypothesis that no alteration has occurred. The results supply a reliable base to develop a methodology for medium to long-term seasonal forecast.

关键词： Climate Variability Trend Analysis Empirical SPI BEST Index PDO Index

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A comparative assessment of empirical and lattice Boltzmann method-based drag models for simulation of gas-solid flow hydrodynamics in a bubbling fluidized bed

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Particuology 2017年第4期15卷 129-137页

作者： Carlos M. Romero Luna Luis R. Carrocci Gretta L.A.F. Arce Ivonete avila UNESP - Sflo paulo State University School of Engineering Department of Energy Laboratory of Combustion and Carbon Capture (LC3) CEP 12.516-410 Guaratinguetd SP Brazil INPE - Brazilian Space Research Institute Combustion and Propulsion Associated I.aboratory CEP 12.630-000 Cachoeira Paulista SP Brazil UNJFSC -Jose Faustino Sanchez Carrion National University Faculty of Chemical and Metallurgical Engineering Advanced Materials and Nanotechnology Research Group Huacho Lima Peru

In simulations of fluidized beds using computational fluid dynamics （CFD）, the description of gas-solid flow hydrodynamics relies on a drag model to account for the momentum transfer between gas and solid phases. Although several studies of drag models have been published, there have been few investigations of the application of lattice Boltzmann method （LBM）-based drag models to bubbling fluidized bed simu- lations. In the present study, a comprehensive comparison of empirical and LBM-based drag models was carried out to assess the performance of these models during simulations of gas-solid flow hydrodynam- ics in a bubbling fluidized bed. A CFD model using the MFIX code based on the Eulerian-Eulerian approach and the kinetic theory of granular flow was used to simulate a 2D bubbling fluidized bed with Geldart B particles. The simulation results were validated by comparison with experimental data. Statistical anal- ysis of the results shows that LBM-based drag models can reliably model gas-solid flow hydrodynamics in a bubbling fluidized bed.

关键词： CFD Drag model Gas-solid flow hydrodynamics Bubbling fluidized bed

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Mean and Interannual Variability of Maize and Soybean in Brazil under Global Warming Conditions

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American Journal of Climate Change 2013年第4期2卷 237-253页

作者： Flávio Justino Evandro Chaves Oliveira Rafael de avila Rodrigues paulo Henrique Lopes Goncalves paulo Jorge Oliveira Ponte Souza Frode Stordal José Marengo Thieres G.da Silva Rafael Coll delgado Douglas da Silva Lindemann Luiz Claudio Costa departamento de Engenharia Agrícola Universidade Federal de ViçosaVicosaBrazil Universidade Federal Rural da Amazônia Instituto Sócio-Ambiental e dos Recursos HídricosBelémBrazil department of Geosciences University of OsloOsloNorway Instituto Nacional de Pesquisas Espaciais Cachoeira PaulistaBrazil Universidade Federal Rural de Pernambuco Unidade Academica de Serra TalhadaSerra TalhadaBrazil Universidade Federal Rural do Rio de Janeiro Instituto de Florestas/Departamento de Ciencias AmbientaisSeropédicaBrazil

Brazil is responsible for 27% of the world production of soybeans and 7% of maize. Mato Grosso and Para states in Brazil are among the largest producer. The viability to the cultivation of maize (Zea mays) and soybeans (Glycine max), for future climate scenarios (2070-2100, GHG) is evaluated based on crop modeling (DSSAT) forced by observational data and regional climate simulations (HadRM3). The results demonstrated that a substantial reduction in the yield in particular for maize may be expected for the end of the 21st century. Distinct results are found for soybeans. By applying the A2 climate changes scenario, soybean yield rises by up top 60% assuming optimum soil treatment and no water stress. However, by analyzing the inter-annual variability of crop yields for both maize and soybean, could be demonstrated larger year-to-year fluctuations under greenhouse warming conditions as compared to current conditions, leading to very low productivity by the end of the 21st century. Therefore, these Brazilian states do not appear to be economically suitable for a future cultivation of maize and soybeans. Improved adaptation measures and soil management may however partially alleviate the negative climate change effect.

关键词： Climate Changes Soybeans Maize

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Artificial reproduction of neotropical fish:Extrusion or natural spawning?

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Natural Science 2013年第7期5卷 1-6页

作者： David Augusto Reynalte-Tataje Sunshine de avila-Simas Juan Ramon Esquivel Garcia Evoy Zaniboni-Filho departamento de Aquicultura Laboratório de Biologia e Cultivo de Peixes de Agua DoceUniversidade Federal de Santa CatarinaCentro de Ciencias AgráriasFlorianópolisBrazil Estacao de Piscicultura Panamá Paulo LopesBrazil Programa de Pós-Graduacao em Aquicultura Departamento de AquiculturaUniversidade Federal de Santa CatarinaCentro de Ciencias AgráriasFlorianópolisBrazil

In captive conditions, most neotropical migratory species do not have the necessary incentive to complete gonadal maturation and spawning, which require induction techniques, usually with the use of hormones. Numerous studies have therefore focused on finding an effective hormonal treatment to induce reproduction for each species. A standard treatment was successfully developed for most of these species, which consists of two doses of Carp Pituitary Extract (CPE), totaling 5.5 mgCPE/kg of fish. However, the best strategy for the subsequent fertilization of gametes is still unclear. This study was conducted with five species of commercial interest that do not reproduce naturally in captivity: pacu Piaractus mesopotamicus, piracanjuba Brycon orbignyanus, curimbatá Prochilodus lineatus, dourado Salminus brasiliensis and piau?u Leporinus macrocephalus. Ninety-nine broodstocks were used, consisting of males and females of the five species to compare two techniques for spawning and fertilization: extrusion followed by the dry method and natural spawning. All fish were induced with two hormone doses, i.e., 0.5 and 5.0 mgCPE/kg, and were subjected to one of the two types of fertilization. The results were compared using the fertilization rate, number of oocytes produced, relative fecundity and the broodstocks' survival rate on days following spawning. All species responded positively to spawning for extrusion, and only S. brasiliensis did not spawn through the natural spawning method. The natural spawning technique provided a higher fertilization rate of eggs and a greater broodstock survival rate (P S. brasiliensis. It was concluded that the natural spawning technique can increase the production of viable eggs and reduce the mortality of species during breeding, except for S. brasiliensis.

关键词： Induced Breeding Spawning Fish Farming Broodstocks Induction Techniques

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