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Static-based early-damage detection using symbolic data analysis and unsupervised learning methods

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Frontiers of Structural and Civil Engineering 2015年第1期9卷 1-16页

作者： Joao Pedro SANTOS Christian CREMONA Andre D. ORCESI paulo silveira Luis CALADO Department of Structures Av. Brasil 101 Lisbon 1700-066 Portugal Technical Center for Bridge Engineering CEREMA B.P. 214 Provins Cedex 77487 France Materials and Structures Department IFSTTAR University Paris-Est 14-20 Boulevard Newton Champs sur Marne Marne la Vallee Cedex2 F-77447 France Department of Civil Engineering Technical University Lisbon Avenida Rovisco Pais Lisbon 1096 Portugal

A large amount of researches and studies have been recently performed by applying statistical and machine learning techniques for vibration-based damage detection. However, the global character inherent to the limited number of modal properties issued from operational modal analysis may be not appropriate for early-damage, which has generally a local character. The present paper aims at detecting this type of damage by using static SHM data and by assuming that early-damage produces dead load redistribution. To achieve this objective a data driven strategy is proposed, consisting of the combination of advanced statistical and machine learning methods such as principal component analysis, symbolic data analysis and cluster analysis. From this analysis it was observed that, under the noise levels measured on site, the proposed strategy is able to automatically detect stiffness reduction in stay cables reaching at least 1%.

关键词： structural health monitoring early-damage detection principal component analysis symbolic data symbolic dissimilarity measures cluster analysis numerical model damage simulations

Leukotriene-A4-Hydrolase and Basic Aminopeptidase Activities Are Related with Collagen-Induced Arthritis in a Compartment-Dependent Manner

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Open Journal of Rheumatology and Autoimmune Diseases 2013年第4期3卷 255-262页

作者： Mariana Trivilin Mendes paulo Flavio silveira Laboratory of Pharmacology Unit of Translational Endocrine Physiology and PharmacologyInstituto ButantanSao PauloBrazil Department of Physiology Instituto de BiociênciasUniversidade de Sao PauloSao PauloBrazil

Objective: Previous study demonstrated the involvement of basic aminopeptidase (APB) activity in the development of collagen-induced arthritis (CIA). Two zinc dependent metalloenzymes (EC 3.***.11.6 and EC 3.***.2.6) are known to exhibit concomitantly APB and leukotriene-A4-hydrolase (LT-A4-H) activities. Influence of the interrelationship between both activities on arthritic processes, however, is presently uncertain. This study aimed to compare these activities in CIA. Methods: CIA was induced in rats and arthritis was assessed macroscopically. Ultracentrifugation was used to separate soluble (S) and solubilized membrane-bound (M) fractions from peripheral blood mononuclear cells (PBMCs) and synovial tissue (ST). Enzyme immunoassay was used to measure LT-A4-H activity, and Real Time Polymerase Chain Reaction was used for evaluating EC 3.***.11.6 and EC 3.***.2.6 gene expressions. Results: The existence of genes for EC 3.***.2.6 and EC 3.***.11.6 was demonstrated in the ST. Compared with control, LT-A4-H activity increased in synovial fluid (SF) and in S-PBMCs of CIA-arthritic and CIA-resistant and in M-ST of CIA-resistant, while it decreased in M-PBMCs of CIA-arthritic and CIA-resistant. In all these locations APB activity remained unchanged or inversely correlated with LT-A4-H activity. Conclusions: LT-A4-H and APB activities in joint-related samples are associated, for the first time, with EC 3.***.2.6 and EC 3.***.11.6 genes, exhibiting a compartment-dependent differential modulation of their specificity, efficiency and/or affinity or an inverse concurrent pattern. Changes in LT-A4-H activity have implications for development or resistance to arthritis in CIA model with a potential to be a diagnostic tool.

关键词： Aminopeptidase Ether Hydrolase Bifunctional Enzyme Eicosanoids

Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice

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Neural Regeneration Research 2022年第2期17卷 450-458页

作者： Carlos Pereira Martins Rodrigo Sebben Paes Gabriela Mantovani Baldasso Eduarda Gomes Ferrarini Rahisa Scussel Rubya Pereira Zaccaron Ricardo Andrez Machado-de-Avila paulo Cesar Lock silveira Rafael Cypriano Dutra Laboratory of Autoimmunity and Immunopharmacology Department of Health SciencesCampus AraranguaUniversidade Federal de Santa CatarinaAraranguáSCBrazil Post-Graduate Program of Neuroscience Center of Biological SciencesUniversidade Federal de Santa CatarinaFlorianópolisSCBrazil Laboratory of Experimental Physiopathology Program of Postgraduate in Science of HealthUniversidade do Extremo Sul CatarinenseCriciumaSCBrazil

Fibromyalgia(FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still unknown, a significant decrease in biogenic amines is a common characteristic in its pathogenesis. Here, our main objective was to investigate the role of dopamine D3/D2 receptor during the reserpine-induced pain in mice. Our results showed that pramipexole(PPX) – a dopaminergic D3/D2 receptor agonist – inhibited mechanical allodynia and thermal sensitivity induced by reserpine. Relevantly, PPX treatment decreased immobility time and increased the number of grooming in the forced swimming test and splash test, respectively. Animals that received PPX remained longer in the open arms than the reserpine group using elevated plusmaze apparatus. The repeated PPX administration, given daily for 4 days, significantly blocked the mechanical and thermal allodynia during FM model, similarly to pregabalin, although it failed to affect the reserpine-induced thermal nociception. Reserpine administration induced significant downregulation of dopamine concentration in the central nervous system, and repeated treatment with PPX restored dopamine levels in the frontal cortex and spinal cord tissues. Moreover, PPX treatment inhibited oxidants production such as DCFH(2′,7′-dichlorodihydrofluorescein) and nitrite, also decreased oxidative damage(carbonyl), and upregulated the activity of superoxide dismutase in the spinal cord. Together, our findings demonstrated the ability of dopamine D3/D2 receptor-preferring agonist in reducing pain and mood dysfunction allied to FM in mice. All experimental protocols were approved by the Universidade Federal de Santa Catarina(UFSC) Ethics Committee(approval No. 2572210218) on May 10, 2018.

关键词： dopamine dopaminergic system fibromyalgia hyperalgesia pain pramipexole reserpine

Benchmarks for Pirá2.0,a Reading Comprehension Dataset about the Ocean,the Brazilian Coast,and Climate Change

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Data Intelligence 2024年第1期6卷 29-63页

作者： paulo Pirozelli Marcos M.José Igor silveira Flávio Nakasato Sarajane M.Peres Anarosa A.F.Brandão Anna H.R.Costa Fabio G.Cozman Universidade de São paulo Ringgold Standard Institution-Instituto de Estudos Avançados Av.370 São Paulo 05508-900Brazil Universidade de São paulo Ringgold Standard Institution-Instituto de Matemática e Estatística Av.370 São Paulo 05508-900Brazil Universidade de São paulo Rua Cayowaá876 apto 141SÃO PAULO 05018-001Brazil Universidade de São paulo Ringgold Standard Institution Escola Politécnica Av.370São Paulo 05508-900Brazil.

Piráis a reading comprehension dataset focused on the ocean,the Brazilian coast,and climate change,built from a collection of scientific abstracts and reports on these *** dataset represents a versatile language resource,particularly useful for testing the ability of current machine learning models to acquire expert scientific *** its potential,a detailed set of baselines has not yet been developed for Pirá.By creating these baselines,researchers can more easily utilize Piráas a resource for testing machine learning models across a wide range of question answering *** this paper,we define six benchmarks over the Pirádataset,covering closed generative question answering,machine reading comprehension,information retrieval,open question answering,answer triggering,and multiple choice question *** part of this effort,we have also produced a curated version of the original dataset,where we fixed a number of grammar issues,repetitions,and other ***,the dataset has been extended in several new directions,so as to face the aforementioned benchmarks:translation of supporting texts from English into Portuguese,classification labels for answerability,automatic paraphrases of questions and answers,and multiple choice *** results described in this paper provide several points of reference for researchers interested in exploring the challenges provided by the Pirádataset.

关键词： Natural language processing Question answering Benchmarks Language resource DomainOriented dataset Scientific knowledge text dataset

Urban forest loss using a GIS-based approach and instruments for integrated urban planning:A case study of Jo?o Pessoa,Brazil

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Journal of Geographical Sciences 2021年第10期31卷 1529-1552页

作者： Leandro Ismael de Azevedo LACERDA JoséAugusto Ribeiro da silveira Celso Augusto Guimarães SANTOS Richarde Marques da SILVA Alexandro Medeiros SILVA Thiago Victor Medeiros do NASCIMENTO Edson Leite RIBEIRO paulo Vitor Nascimento de FREITAS Federal University of Paraíba Laboratory of Urban and Built Environment-LAURBE58051-900 João PessoaParaíbaBrazil Federal University of Paraíba Department of Architecture and Urbanism58051-900 João PessoaPBBrazil Federal University of Paraíba Department of Civil and Environmental Engineering58051-900 João PessoaPBBrazil Federal University of Paraíba Department of Geosciences58051-900 João PessoaPBBrazil Ministry of Cities Setor de Autarquias SulQuadra 01Lote 01/06Bloco HEd.Telemundi II70070-010 BrasíliaDFBrazil

Urban forests play an important role in the thermal comfort and overall life of local populations in large-and medium-sized *** study analyzes urban forest loss and maps land use and land cover(LULC)changes between 1991 and 2018 by evaluating the use of urban planning instruments for the mitigation of urban forest loss in Jo?o Pessoa,*** this purpose,satellite-derived LULC images from 1991,2006,2010 and 2018 and data on urban forest loss areas obtained using the Google Earth Engine were *** addition,this paper also discusses the instruments used for integrated urban planning,which are(a)the legal sector,responsibility and nature;(b)the urban expansion process;and(c)the elements of urban *** results show a clear shift in land use in the study *** major changes in LULC classes occurred in urban areas and herbaceous vegetation,while the greatest loss was in arboreal/shrub ***,an increase in the pressure to occupy zones intended for environmental preservation could be *** results showed similar accuracies with other studies and more spatial *** characteristics of the patterns,traces,and hotspots of urban expansion and forest cover loss were *** highlighted the potential use of this proposed framework to be applied and validated in other parts of the world to help better understand and quantify various aspects of urban-related problems such as urban forest loss mapping using instruments for integrated urban planning and low-cost approaches.

关键词： integrated planning mapping thematic synthesis urban afforestation urban planning

Antimicrobial peptides as a feed additive alternative to animal production, food safety and public health implications: An overview

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Animal Nutrition 2021年第3期7卷 896-904页

作者： Raiza F.silveira Cesar A.Roque-Borda Eduardo F.Vicente Sao paulo State University School of Agricultural and Veterinarian SciencesJaboticabalSao PauloBrazil Sao paulo State University School of Sciences and EngineeringTupaSao PauloBrazil

In the last few years,feed additives have been used in animal nutrition to improve nutrient utilization,health parameters and animal ***,the use of antibiotics as feed additives has allowed the occurrence of antimicrobial resistance(AMR),which can bring as a consequence,an increase in the morbidity and mortality of diseases that were previously treatable with *** this context,antimicrobial peptides(AMP)have appeared as a promising strategy because they have multiple bio-logical activities and represent a powerful strategy to prevent the development of resistant *** the small number of studies applied in vivo,AMP appear as a potent alternative to the use of antibiotics in animal nutrition,due to an increase in feed efficiency and the prevention/treatment of some animal *** review discusses the problems associated with antimicrobial resistance and the use of AMP as a strong candidate to replace conventional antibiotics,mainly in the animal industry.

关键词： Additive Antimicrobial peptide Broiler Cattle Laying hen Pig

Starch Digestibility and Functional Properties of Rice Starch Subjected to Gamma Radiation

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Rice science 2018年第1期25卷 42-51页

作者： Luís Fernando POLESI Silene Bruder silveira SARMENTO Solange Guidolin CANNIATTI-BRAZACA Center for Nuclear Energy in Agriculture University of Sao Paulo Department of Food Engineering Federal University of Rondonia Department of Agri-Food Industry Food and NutritionLuiz de Queiroz College of AgricultureUniversity of Sao Paulo

This study investigated the effect of gamma radiation on the digestibility and functional properties of rice *** cultivars IRGA417 and IAC202 were used for isolation of starch by the alkaline *** samples were irradiated with 1,2 and 5 k Gy doses of ^(60)Co at a rate of 0.4 k Gy/h.A control sample,which was not irradiated,was used for *** and control starches were characterized by in vitro starch digestibility,total dietary fiber,color,water absorption index,water solubility index,syneresis,swelling factor,amylose leaching,pasting properties and gel *** changed starch digestibility differently in either *** radiation doses promoted increase in the color parameter b*(yellow),elevation in the capacity to absorb water,and solubility in water as well as the amylose leached from granules for both *** properties showed a decrease that was proportional to the dose applied,caused by the depolymerization of starch *** firmness of the starch from IAC202 was inversely proportional to the radiation dose applied,whereas for IRGA417,there was a reduction at 5 k Gy *** starches can be modified by irradiation to exhibit different functional characteristics and they can be used by the food industries in products such as soups,desserts,flans,puddings and others.

关键词： Oryza sativa irradiation viscosity swelling amylose starch digestibility

Intraguild niche partitioning in granivorous birds from the late past

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Avian Research 2023年第1期14卷 70-77页

作者： Ana B.Navarro Juliano A.Bogoni Marcelo Z.Moreira Luís F.silveira Museu de Zoologia da Universidade de Sāo paulo Secāo de AvesAvNazaré48104263-000São PauloSPBrazil Universidade de Sāo paulo Escola Superior de Agricultura"Luiz de Queiroz"Departamento de Ciências FlorestaisLaboratório de EcologiaManejo e Conservacāo de Fauna Silvestre(LEMaC)Av.Pádua Dias 1113418-900PiracicabaSPBrazil Universidade de Sāo paulo Centro de Energia Nuclear na AgriculturaLaboratório de Ecologia IsotópicaAv.Centenário 30313416-903PiracicabaSPBrazil

Niche partitioning is a widespread ecological strategy within trophic guilds,ensuring the coexistence of sympatric species by reducing interspecific *** isotope analysis of carbon and nitrogen and isotopic niche metrics(width and overlap)are used as a proxy to investigate niche partitioning among species of a *** our study,we investigated if niche partitioning was an ecological mechanism contributing to the coexistence of granivorous birds from the same geographic region along time,employing an isotopic *** sampled and isotopically analyzed(δ^(13)C andδ^(15)N values)wing feathers from 58 specimens of granivorous birds collected between 1900 and 1966 in southeastern *** grouped birds according to the main habitat type used by them(forest:Cyanoloxia brissonii,Leptotila and Leptotila verreauxi;and grassland:Columbina squammata and Sicalis flaveola).We used the Isotopic Richness(IRic)metric to measure the isotopic niche width and the Isotopic Similarity(ISim)and Isotopic Nestedness(INes)metrics to measure the niche overlap between groups and *** results of low isotopic niche overlap suggest that common granivorous birds had a clear niche partitioning in southeastern Brazil in the late past,especially through foraging in distinct habitat types(forest and grassland;ISim=0.1,INes=0.2).Niche overlaps in almost all species-by-species comparisons were low(ISim≤0.3,INes≤0.4),except between *** and ***(ISim=0.6,INes=1.0).These results suggest that these birds,belonging to the same trophic guild,coexisted through niche and resource *** being considered a plastic trophic guild,the isotopic niche partitioning among granivorous birds indicates that each of these species uses a set of specific resources and *** raises an ecological concern about the homogenization of landscapes across the Neotropics,oversimplifying food resources and habitats to granivorous birds.

关键词： Atlantic forest Avian ecology Cerrado Community ecology Diet Foraging ecology Habitat use Trophic relations

Starch Digestibility and Physicochemical and Cooking Properties of Irradiated Rice Grains

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Rice science 2017年第1期24卷 48-55页

作者： Luís Fernando POLESI Manoel Divino da MATTA JUNIOR Silene Bruder silveira SARMENTO Solange Guidolin CANNIATTI-BRAZACA Department of Food Engineering Federal University of RondoniaAriquemes 76872-848RondoniaBrazil Department of Agroindustry Food and NutritionCollege of Agriculture Luiz de QueirozUniversity of Sao PauloPiracicaba 13418-900Sao PauloBrazil

This study evaluated the starch digestibility, physicochemical properties and cooking characteristics of polished rice（varieties IRGA417 and IAC202） subjected to the doses of 0（as the control）, 1, 2 and 5 k Gy of gamma radiation. The highest dose decreased the apparent amylose content, peak viscosity, water absorption and volume expansion. Irradiation increased the solid loss by 119% and 187% for IAC202 and IRGA417, respectively, when comparing the higher dose with the control. For IAC202, irradiation decreased the rapidly digestible starch and increased the slowly digestible starch（SDS） and resistant starch（RS）. IRGA417 showed an elevation of SDS and a reduction in RS. And 1 k Gy dose of gamma radiation generated the highest level of RS for both the two varieties and presented the smallest changes in other physicochemical and cooking properties.

关键词： starch cooking viscosity gamma irradiation grains Starch granules chains physiological