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Anaphylactic Shock Due to Psyllium (<i>Plantago ovate</i>Seed) Allergy: A Case Report

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Food and Nutrition Sciences 2022年第1期13卷 1-5页

作者： paula Ollo morales Marta Velasco Azagra Carlota Martel Martin Marta Gutiérrez Niso Nagore Bernedo Belar Maria Teresa Audicana Berasategui Allergy and Immunology Department Hospital Universitario Araba (HUA) Vitoria-Gasteiz Spain

The seeds of Plantago ovata, called psyllium or ispaghula, have been used in the preparation of bulk laxatives. Nowadays, it is also used as an ingredient in bakery and breakfast cereals to increase dietary fiber and to give baking products fluffiness and viscosity. Mostly, there are described cases of occupational allergy that handle Plantago ovata seeds in powder laxatives and some cases of anaphylaxis after eating products containing psyllium. This case report is about a geriatric assistant who had an anaphylactic shock after eating a multigrain gluten-free piece of bread containing psyllium, who presented a positive skin test with psyllium in the allergy study. We recommended to the patient to avoid the ingestion and the inhalation at work of Plantago ovata seeds and to carry self-injectable adrenaline. With this case, we would like to highlight the growing uses of psyllium, especially in bakery products, and that it can behave like a hidden allergen.

关键词： Plantago ovate Psyllium Ispaghula Anaphylaxis Occupational Allergy

Systemic Inflammation Response Index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 386-397页

作者： Vilma Pacheco-Barcia Sara Custodio-Cabello Fatima Carrasco-Valero Magda Palka-Kotlowska Axel Mariño-Mendez Alberto Carmona-Bayonas Javier Gallego A J Muñoz Martín paula Jimenez-Fonseca Luis Cabezon-Gutierrez Department of Medical Oncology Hospital Universitario de TorrejonMadrid 28850Spain Department of Internal Medicine Hospital Universitario de TorrejonMadrid 28850Spain Department of Medical Oncology Hospital Universitario Central de AsturiasOviedo 33011Spain Department of Medical Oncology Hospital Universitario Morales MeseguerUniversity of MurciaMurcia 30001Spain Department of Medical Oncology Hospital General Universitario de ElcheElche 03202Spain Department of Medical Oncology Hospital General Universitario Gregorio MarañónUniversidad Complutense MadridMadrid 28007Spain Universidad Francisco de Vitoria Madrid 28223Spain

BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains *** To study the prognostic significance of SIRI and weight loss in metastatic pancreatic *** The PANTHEIA-Spanish Society of Medical Oncology(SEOM)study is a multicentric(16 Spanish hospitals),observational,longitudinal,non-interventional initiative,promoted by the SEOM Real World-Evidence work *** pilot study sought to analyze the association between weight loss and inflammatory status as defined by *** cohort stems from a proof-of-concept pilot study conducted at one of the coordinating *** with pathologically confirmed metastatic pancreatic adenocarcinoma,treated from January 2020 to January 2023,were *** index was calculated using the product of neutrophil and monocyte counts,divided by lymphocyte counts,obtained within 15 days before initiation *** study evaluated associations between overall survival(OS),SIRI and weight *** A total of 50 patients were included.66%of these patients were male and the median age was 66 *** sites:36%liver,12%peritoneal carcinomatosis,10%lung,and 42%multiple *** the first line palliative chemotherapy treatments:50%received gemcitabine plus nab-paclitaxel;28%,modified fluorouracil,leucovorin,irinotecan and oxaliplatin,and 16%were administered gemcitabine.42%had a weight loss>5%in the three months(mo)preceding diagnosis.21 patients with a SIRI≥2.3×10^(3)/L exhibited a trend towards a lower median OS compared to those with a SIRI5%weight loss before diagnosis,the median OS was 6 mo,in contrast to 19 mo for those who did not experience such weight loss(P=0.003).Patients with a weight loss>5%showed higher SIRI *** difference was statistically significant(P<0.000).For pat

关键词： Pancreatic cancer Nutrition Prognostic factor Inflammation Advanced cancer Systemic inflammatory response index Weight loss

Histologic and molecular features of small well-differentiated pancreatic neuroendocrine tumors associated with the development of liver metastases

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Hepatobiliary Surgery and Nutrition 2019年第4期8卷 433-435页

作者： paula Jiménez-Fonseca Patricia morales del Burgo Felipe Alvarez-Mancenido Department of Medical Oncology Hospital Universitario Central de AsturiasOviedoSpain Department of Pathology Hospital Universitario Central de AsturiasOviedoSpain Department of Pharmacology Hospital Universitario Central de AsturiasOviedoSpain

The incidence of neuroendocrine neoplasms (NEN) has grown by a factor of 6.4 between 1973 and 2012 (1). According to the United States Surveillance, Epidemiology, and End Results (SEER), some 50% of all NEN, 3.56×10^5, are gastroenteropancreatic (GEP) in origin, including 1.05, 10.4, 0.48×10^5 of the small intestine, rectum, and pancreas, respectively. Like the Spanish group, others have reported a higher incidence of pancreatic NEN (P-NEN) (2). Given its typically indolent course, GEP-NENs are the second most prevalent tumors of the digestive system, surpassed only by colorectal cancer, underscoring the importance of understanding them, their diagnosis, and efficient treatment strategies.

关键词： neoplasms intestine diagnosis

Selecting the best:Interspecific and age-related diet differences among sympatric steppe passerines

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Avian Research 2023年第4期14卷 611-622页

作者： Julia Zurdo paula Gomez-Lopez Adrian Barrero Daniel Bustillo-de la Rosa Julia Gomez-Catasús Margarita Reverter Cristian Perez-Granados Manuel B.morales Juan Traba Terrestrial Ecology Group Department of EcologyUniversidad Autonoma de Madrid(TEG-UAM)MadridSpain Centro de Investigacion en Biodiversidady Cambio Global Universidad Autonoma de Madrid(CIBC-UAM)MadridSpain Ecology Department/IMEM“Ramon Margalef” Universidad de AlicanteAlicanteSpain

Parental food provisioning is crucial for the growth and survival of *** rate depends on food quality and food supplied to offspring may differ from what adults use for their *** the case of steppe passerine birds,detailed characterization on nestling dietary composition,as well as prey choice and resource partitioning among species,is a pending *** differences between nestlings and adults remain also largely *** using faecal DNA metabarcoding,we described the diet of nestlings and adults of five shrub-steppe passerine species over the 2017–2019 breeding seasons in central *** also monitored arthropod availability in the field to assess dietary *** expected interspecific dietary differences to limit competition for food resources among sympatric species,as well as parental selection of high quality prey for *** also predicted age-related differences,with nestlings being fed nutrient-rich prey more frequently than *** main arthropod orders provisioned to nestlings were Orthoptera,Julida,Araneae and *** of the different species showed high interspecific diet overlap,indicating both a coincidence in growth needs among bird species and no or little limitation of the most profitable resources during the breeding *** of all species showed higher diet richness than nestlings,and age-related differences in prey composition were mainly driven by the selection of the most easily digestible,larger protein-and calcium-rich prey for nestlings,which may favour their rapid growth,and avoiding highly sclerotized and less nutritional prey such as *** study sheds light on the basic ecology and conservation of these declining steppe birds,indicating that interspecific competition may not be a major factor during the breeding *** the current global decline of arthropods,further long-term research would be necessary,along with the implementation of effective conservation measure

关键词： 18S Faecal material Nestling diet Prey choice Resource partitioning

Factors That Motivate Undergraduate Students： An Analysis at a University in Mexico

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Journal of Modern Accounting and Auditing 2016年第1期12卷 52-59页

作者： Selene Viridiana Perez Ramirez paula Ponce Lazaro Silvia Cartujano Escobar Crisoforo Alvarez Violante Roque Lopez Tarango Enrique Pineda Figueroa Ma. Isabel morales Rangel Autonomous University of Morelos State Morelos Mexico Mexican Distance Education University Mexico

The objective of this research was to analyze （or characterize） what motivational factors are involved in the continuity of the academic development of students in the Graduate School of Jojutla. The study is quantitative, descriptive, and transversal. The population is composed of 346 students who entered college in 2014. A sample of 52 students out of this population was selected, from the majors of Business Management, Accounting, Law, Environmental Sciences, Psychology, and Computer Science. The data collection instrument was developed by Esquivel and Arjona （2003）, which measured the dimensions of security, affiliation or affection, self-fulfillment, achievement, power, recognition, and knowledge. The results showed that 72.7% of new students place a very high value on the knowledge dimension： learning new things, improve study skills, do research, better overall job training, and interest in learning. However, in other dimensions, such as affiliation or affection, the percentage given by students is 9. 1%. While the study consists of a small sample, the results provide important information on motivation as a factor that must be considered and evaluated throughout the academic record of the student in order to prevent dropouts and increase terminal efficiency.

关键词： motivation students upper level

Role of Chemotherapy in Advanced Gastric Cancer: Review from a Latin American Perspective

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Journal of Cancer Therapy 2016年第1期7卷 1-12页

作者： Marcelo Garrido paula Jimenez-Fonseca Maria Pilar Solis Alberto Carmona-Bayonas Sebastian Mondaca Bruno Nervi Jorge Madrid Cancer Center Hematology-Oncology Department Pontifical Catholic University Santiago Chile Medical Oncology Digestive Tumors University Central Asturias Hospital Oviedo Spain Medical Oncology Digestive Tumors Morales Meseguer Hospital Murcia Spain

Gastric cancer (GC) is the fourth most common neoplasm and the second leading cause of cancer-related death worldwide. In Latin America (LA), the burden of this disease is higher and is the leading cause of cancer death in some countries. Chemotherapy is the standard treatment for advanced-stage GC. However, the best regimen for specific populations, such as LA, is as yet unknown. Cisplatin and fluoropyrimidine continue to be the standard of care in light of the findings of phase III studies, while docetaxel, cisplatin, and 5-fluorouracil (5-FU) are alternatives for patients with suitable overall health. Oxaliplatin or irinotecan with fluoropyrimidine can also be used in elderly patients who are not candidates for cisplatin, or have a limited performance status. This review examines studies conducted in LA. Patients from LA are under-represented in multicenter trials of chemotherapy and targeted therapies. The major challenges currently lie in implementing strategies in which patients are selected on the basis of regional, racial or molecular characteristics, to consider the molecular subtype of GC for enrolment, and in selecting patients according to prognostic factors to optimize the benefits of chemotherapy.

关键词： Advanced Gastric Cancer Chemotherapy Targeted Therapy Molecular Classification Latin America