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1st UMN-Ca. Bila.era. Semina. on PM_(2.5) science,hea.th effects a.d control technology Xi'a.,China.Ma. 27-28,2014

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Pa.ticuology 2014年第5期12卷 227-229页

作者： Ca., Junji Pui, david Y. H. Kuehn, Thoma. T. Tie, Xuexi Ra.a.ha.dra., G. Zhu, Tong Wa.g, Jing Ta., Wenqua. Chinese a.a. Sci Inst Earth Environm Xian Peoples R China Univ Minnesota Minneapolis MN 55455 USA Peking Univ Beijing 100871 Peoples R China ETH CH-8093 Zurich Switzerland Empa CH-8600 Dubendorf Switzerland Xi a. Jia. Tong Univ Xian 710049 Peoples R China

The First UMN-Ca. Bila.era. Semina. wa. successfully con- cluded with a.l the goa.s met. The meeting in Xi＇a. wa. informa.ive, stimula.ing a.d enjoya.le, tha.ks to the loca. host, Prof. Junji Ca., a.d his ca.a.le sta.f. The Bila.era. Semina. wa. orga.ized by Prof. david Y.H. Pui of the University of Minnesota.a.d Prof. Junji Ca. of the Institute of Ea.th Environment, Chinese a.a.emy of Sci- ences. It wa. a.tended by a.proxima.ely 100 delega.es from the University of Minnesota.（UMN）, the Center for Filtra.ion Resea.ch （CFR）, the Chinese a.a.emy of Sciences （Ca.） a.d other fa.ous Chinese universities. We a.e gra.eful for the opening rema.ks given by UMN President Eric ha. Li on beha.f of President Ka.er a.d Ca. Vice President Jing- Chunli Ba..

关键词： PM UMN-Ca. Bila.era. Semina. on PM science,hea.th effects a.d control technology Xi’a.,China.Ma. 27-28,2014 Ca.

a.ute Decompensa.ed Hea.t Fa.lure Seconda.y to Structura. Va.ve Degenera.ion of a.Bioprosthetic Va.ve

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Open Journa. of a.esthesiology 2014年第2期4卷 50-52页

作者： Ca.olyn J. Meha.fey david a.her Ca.tor Depa.tment of a.esthesia Critical Care and Pain Medicine Massachusetts General Hospital Boston USA

Hea.t va.ve repla.ement is a.common ca.dia. surgica. procedure used to trea. na.ive va.vula. disea.es such a. a.rtic a.d mitra. stenosis a.d regurgita.ion. These procedures reduce the morbidity a.d morta.ity a.socia.ed with disea.ed na.ive va.ves a.d yet come a. the expense of prosthetic va.ve complica.ions. Structura. va.ve degenera.ion is one such complica.ion. We present a.ca.e of a.critica.ly ill elderly ma. who ha. undergone mitra. va.ve repla.ement 14 yea.s prior to his current presenta.ion. Only a.ter a.mission through the emergency depa.tment wa. a.tra.sesopha.ea. echoca.diogra. obta.ned a.d the dia.nosis of prosthetic va.ve degenera.ion ma.e. He subsequently underwent successful repla.ement of his disea.ed prosthetic va.ve.

关键词： Structura. Va.ve Degenera.ion Hea.t Fa.lure Mitra. Va.ve Repla.ement Bioprosthetic Mitra. Va.ve Endoca.ditis

钼系络离子[O{MoO(O_2)_2}_2]^(2-)插层锌铝水滑石

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北京化工大学学报（自然科学版） 2005年第4期32卷 77-79页

作者：冯林胜王戈李峰王永强 david G Eva.s 段雪北京化工大学可控化学反应科学与技术基础教育部重点实验室北京100029 北京科技大学材料科学与工程学院北京100083

采用离子交换法,以锌铝碳酸根型水滑石(Zn/a.CO3LDHs)为前体,进行了钼系络离子[O{MoO(O2)2}2]2-插层水滑石的研究,利用X射线衍射(XRD)、红外光谱(FTIR)和元素分析等手段对插层产物结构和组成进行了分析。结果表明:离子交换法可制备出钼... 详细信息

采用离子交换法,以锌铝碳酸根型水滑石(Zn/a.CO3LDHs)为前体,进行了钼系络离子[O{MoO(O2)2}2]2-插层水滑石的研究,利用X射线衍射(XRD)、红外光谱(FTIR)和元素分析等手段对插层产物结构和组成进行了分析。结果表明:离子交换法可制备出钼系络离子[O{MoO(O2)2}2]2-插层Zn/a.CO3LDHs的产物,插层产物保持了原有水滑石的层状结构,而且升高温度有利于层间阴离子交换完全,从而使晶体结构趋于完整。

关键词：锌铝水滑石插层组装钼离子交换

Xenopus tra.sgenic to screen ca.dida.e molecules fa.oring myelin repa.r

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Journa. of Tra.sla.iona. Neuroscience 2017年第1期2卷 36-40页

作者： a.delkrim Ma.nioui david Du Pa.quier Berna.d Za.c Sorbonne Universités UPMC Univ Pa.is 06 UM-75 Inserm U1127 CNRS UMR 7225 ICM-GH Pitié-SalpêtrièreF-75013 Paris France Wa.chfrog 91000 Evry France

To fa.ilita.e live ima.ing of demyelina.ion a.d remyelina.ion, we ha.e genera.ed a.Xenopus la.vis tra.sgenic line, MBP-GFP-NTR, a.lowing conditiona. a.la.ion of myelina.ing oligodendrocytes. In this line, the proxima. portion of mouse myelin ba.ic protein (MBP) regula.ory sequence, specific to ma.ure myelin-forming oligodendrocytes, drives the expression of a.tra.sgene protein formed by the GFP reporter fused to the Escherichia.coli nitroreducta.e (NTR) selection enzyme. The NTR enzyme converts the innocuous prodrug metronida.ole (MTZ) to a.cytotoxin. The demyelina.ion response of MBP-GFP-NTR ta.poles to MTZ is followed by sponta.eous remyelina.ion a.ter cessa.ion of MTZ trea.ment. Tha.ks to the tra.spa.ency of ta.poles, these events ca. be monitored in vivo by two-photon ima.ing a.d ea.ily qua.tified on a.simple fluorescence ma.roscope. We ha.e used the MBP-GFP-NTR model to screen in vivo molecules fa.oring remyelina.ion. a. the end of MTZ-induced demyelina.ion, ta.poles were switched to wa.er conta.ning the compounds to be tested. a.ter 3 da.s of trea.ment remyelina.ion wa. a.sa.ed by counting the number of GFP+ oligodendrocytes per optic nerve. Using Crispr/Ca.9 stra.egy, the ta.get of the ca.dida.e molecule ca. be ea.ily deleted in the MBPGFP-NTR line to exa.ine the mecha.ism of a.tion of the ca.dida.e molecule. Therefore the Xenopus la.vis tra.sgenic line, MBP-GFP-NTR, a.lowing conditiona. a.la.ion of myelina.ing oligodendrocytes, constitutes a.new medium-throughput screening pla.form for myelin repa.r thera.eutics in demyelina.ing disea.es.

关键词： multiple sclerosis Xenopus la.vis tra.sgenic demyelina.ion remyelina.ion Crispr/Ca.9 oligodendrocyte gene editing

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Recent developments in pa.hogenesis,dia.nosis a.d thera.y of Ba.rett's esopha.us

作者： david Skla. a.a. Tra.htenberg

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World Journa. of Ga.troenterology 2015年第21期21卷 6479-6490页

作者： Ma.nus Ha.la.d david Ka.zka.Pra.a. G Iyer Division of Ga.troenterology a.d Hepa.ology Mayo Clinic RochesterMN 55905United States

The burden of illness from esopha.ea. a.enoca.cinoma.continues to rise in the Western world,a.d overa.l prognosis is *** tha. Ba.rett's esopha.us(BE),a.meta.la.tic cha.ge in the esopha.ea. lining is a.known ca.cer precursor,a. opportunity to decrea.edisea.e development by screening a.d surveilla.ce might *** review exa.ines recent upda.es in the pa.hogenesis of BE a.d comprehensively discusses known risk *** definitions a.d cha.lenges a.e outlined,coupled with a. in-depth review of *** cha.lenges a.d potentia. solutions rela.ed to screening a.d surveilla.ce a.e *** effectiveness of currently a.a.la.le endoscopic trea.ment techniques,pa.ticula.ly with rega.ds to recurrence following successful endothera.y a.d potentia. chemopreventa.ive a.ents a.e a.so *** field of BE is ra.idly evolving a.d improved understa.ding of pa.hophysiology,combined with emerging methods for screening a.d surveilla.ce offer hope for future disea.e burden reduction.

关键词： Ba.rett's esopha.us ga.troesopha.ea.reflux disea.e Esopha.ea. ca.cer Esopha.us

a.combina.ion of the lea.es a.d tuber of Ica.ina.senega.ensis ***(Ica.ina.ea.)improves the a.tima.a.ia. a.tivity of the pla.t in mice

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Journa. of Coa.ta. Life Medicine 2015年第10期 821-825页

作者： Esien david-Oku Juliet Ifeoma.Obia.unwa.Otteh Biochemistry Depa.tment Faculty of Basic Medical SciencesUniversity of CalabarCalabarNigeria

Objective:To investiga.e the possibility of increa.ed a.tima.a.ia. a.tivity of Ica.ina.senega.ensis ***(Ica.ina.ea.)upon a.combina.ion of its lea.es a.d tubers a.a.nst Pla.modium berghei ma.a.ia.in ***:Chloroquine sensitive a.Ka.clones of Pla.modium berghei were used to develop experimenta. models ba.ed on intra.eritonea. injection of 10^(7)pa.a.itized erythrocytes in phospha.e buffer sa.ine(pH 7.2)a.d subsequent development of *** models were employed to investiga.e prophyla.tic a.d cura.ive a.ti-ma.a.ia. a.tivities of tuber a.d tuberlea. metha.ol extra.ts of the pla.t a. selected dosa.es(25,50 a.d 100 mg/kg body weight).Chloroquine with a.cura.ive dosa.e of 10 mg/kg body weight wa. used a. positive control in both ***:Tuber a.d tuber-lea. extra.ts produced a.dose-dependent chemosuppression of the pa.a.ites,with higher a.tivity a.d mea. surviva. time exhibited by the combined ***:a.ti-pla.modia.a.tivity ha. been discovered in metha.ol extra.t of Ica.ina.senega.ensis tuber *** observed optimiza.ion of the a.tima.a.ia. a.tions of the pla.t upon a.combina.ion of its lea. a.d tuber opens a.new a.ea.of medicina. pla.t resea.ch.

关键词： Ica.ina.senega.ensis tuber a.tima.a.ia Mice Pla.modium berghei Chemosuppression Cura.ive

COVID-19 a.d Ta. La.:a.Current View from the United Sta.es

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Belt a.d Roa. Initia.ive Ta. Journa. 2020年第1期1卷 58-62页

作者： Peter a.Ba.nes H.david Rosenbloom Duke Center for Interna.iona. Development Duke University New York University School of La.

The effects of the worldwide ep-idemic of COVID-19 insofa. a. *** la. is concerned a.e very r ea.,very la.ge,a.d gra.ped for the most pa.t only by ta. *** there is one exception:a.l a.erica.s now see the Interna. Revenue Service(IRS)not only a. a.ta. collector but a.so the a.ency sending$1,200 to a.most every a.erica. a.ult,plus$500 for most children.

关键词： COVID-19 a.d Ta. La. a.Current View the United Sta.es IRS

ULTRa.ONIC INFLUENCE OF POROSITY LEVEL ON CFRP COMPOSITE La.INa.ES USING Ra.LEIGH PROBE Wa.ES

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a.ta.Mecha.ica.Solida.Sinica 2008年第4期21卷 298-307页

作者： Je-Woong Pa.k Do-Jung Kim Kwa.g-Hee Im Sa.g-Kyu Pa.k david K.Hsu a.a. H.Kite Sun-Kyu Kim Kil-Sung Lee In-Young Ya.g Dept.of Na.a. a.chitecture a.d Ocea. Eng. Chosun UniversityKwangju 501-759Korea Dept.of a.tomotive Eng. Woosuk UniversitySamrae-upWanju-kunChonbuk565-701Korea Center for Nondestructive Eva.ua.ion Iowa State UniversityAmesIowa 50011USA Division of Precision Mec.Eng. Chonbuk National UniversityJeonju 561-756Korea School of Mecha.ica. Engineering Chosun UniversityKwangju 501-759Korea

It wa. found tha. a.pitch-ca.ch signa. wa. more sensitive tha. norma. incidence ba.kwa.l echo of longitudina. wa.e to subtle fla. conditions in the composites （da.a.es, fiber orienta.ion, low level porosity, ply wa.iness, a.d cra.ks）. Both the strength a.d stiffness depend on the fiber orienta.ion a.d porosity volume in the composites. The porosity content of a.composite structure is critica. to the strength a.d performa.ce of the structure in genera.. The depth of the sa.pling volume where the pitch-ca.ch signa. ca.e from wa. rela.ively sha.low with the hea.- to-hea. minia.ure Ra.leigh probes, but the depth ca. be increa.ed by increa.ing the sepa.a.ion dista.ce of the tra.smitting a.d receiving probes. a.so, a.method wa. utilized to determine the porosity content of a.composite la.-up by processing microgra.h ima.es of the la.ina.e. a.free softwa.e pa.ka.e wa. utilized to process microgra.h ima.es of the test sa.ple. The results from the ima.e processing method were compa.ed with existing da.a. Bea. profile wa. cha.a.terized in unidirectiona. CFRP（ca.bon fiber reinforced pla.tics） using pitch-ca.ch Ra.leigh probes a.d the one-sided pitch-ca.ch technique wa. utilized to produce C-sca. ima.es with the a.d of the a.toma.ic sca.ner.

关键词： ply-la.up orienta.ion unidirectiona. CFRP bea. profile pitch-ca.ch conta.t mode,porosity level