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多频移动手机的无线性能最佳化方法

电子产品世界 2004年第1A期11卷 57-58,69页

作者： patrick n.morgan Silicon Laboratories Inc.

移动电话正演变成为一种面向数据的设备,彩色屏幕、数字相机和板上内存等功能也逐渐成为主流,用来支持各种面向数据的应用,包括多媒体消息、移动游戏、上网、收发邮件和移动商务.为推动此发展趋势,移动电话业者开始为现有的GSM网络增加... 详细信息

移动电话正演变成为一种面向数据的设备,彩色屏幕、数字相机和板上内存等功能也逐渐成为主流,用来支持各种面向数据的应用,包括多媒体消息、移动游戏、上网、收发邮件和移动商务.为推动此发展趋势,移动电话业者开始为现有的GSM网络增加高速E-GPRS(EDGE)以及WCDMA(UMTS)数据功能,并向后兼容于既有的服务.

关键词：手机无线频移移动游戏 UMTS 多频多媒体消息收发邮件内存数据

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada patrick Heimel Markus Kerbl LászlóGál Sylvia nürnberger Barbara Schaedl James Ferguson nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal nógrádi Andreas H.Teuschl-Woller David Hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tnGCs). However, the use of tnGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tnGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tnGCs and compared the various features of these improved silk^(+) tnGCs with the tubes without holes(silk^(–) tnGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tnGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tnGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tnGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tnGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

The expanding Asgard archaea and their elusive relationships with Eukarya

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mLife 2022年第1期1卷 3-12页

作者： Violette Da Cunha morgan Gaïa patrick Forterre CEA CNRSInstitute for Integrative Biology of the Cell(I2BC)UniversitéParis-SaclayGif-sur-YvetteFrance Génomique Métabolique GénoscopeInstitut François JacobCEACNRSUniv.EvryUniversitéParis-SaclayEvryFrance Département de Microbiologie Institut PasteurParisFrance

The discovery of Asgard archaea and the exploration of their diversity over the last 6 years have deeply impacted the scientific community working on eukaryogenesis,rejuvenating an intense debate on the topology of the universal tree of life(uTol).Here,we discuss how this debate is impacted by two recent publications that expand the number of Asgard lineages and eukaryotic signature proteins(ESPs).We discuss some of the main difficulties that can impair the phylogenetic reconstructions of the uTol and suggest that the debate about its topology is not *** notably hypothesize the existence of horizontal gene transfers between ancestral Asgards and proto-eukaryotes that could result in the observed abnormal behaviors of some Asgard ESPs and universal marker *** hypothesis is relevant regardless of the scenario considered regarding *** implies that the Asgards were already diversified before the last eukaryotic common ancestor and shared the same biotopes with *** suggest that some Asgards might be still living in symbiosis today with modern Eukarya.

关键词： Asgard horizontal gene transfer molecular phylogeny tree of life

Association between high deductible health plan coverage and age at pediatric umbilical hernia repair

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World Journal of Pediatric Surgery 2023年第2期6卷 70-76页

作者： morgan E Doty Lindsay A Gil Jennifer n Cooper The Ohio State University College of Medicine ColumbusOhioUSA Department of Surgery Nationwide Children's HospitalThe Ohio State UniversityColumbusOhioUSA Department of Pediatrics Nationwide Children's HospitalThe Ohio State UniversityColumbusOhioUSA

Background High deductible health plans(HDHPs)are associated with the avoidance of both necessary and unnecessary *** hernia repair(UHR)is a procedure that is frequently unnecessarily performed in young children,contrary to best practice *** hypothesized that children with HDHPs,as compared with other types of commercial health plans,are less likely to undergo UHR before 4 years of age but are also more likely to have UHR delayed beyond 5 years of *** Children aged 0-18 years old residing in metropolitan statistical areas(MSAs)who underwent UHR in 2012-2019 were identified in the IBM Marketscan Commercial Claims and Encounters Database.A quasi-experimental study design using MSA/year-level HDHP prevalence among children as an instrumental variable was employed to account for selection bias in HDHP ***-stage least squares regression modeling was used to evaluate the association between HDHP coverage and age at *** A total of 8601 children were included(median age 5 years,IQR 3-7).Univariable analysis revealed no differences between the HDHP and non-HDHP groups in the likelihood of UHR being performed before 4 years of age(27.7%vs 28.7%,p=0.37)or after 5 years of age(39.8%vs 38.9%,p=0.52).Geographical region,metropolitan area size,and year were associated with HDHP *** variable analysis demonstrated no association between HDHP coverage and undergoing UHR at5 years of age(p=0.87).Conclusions HDHP coverage is not associated with age at pediatric *** studies should investigate other means by which UHRs in young children can be avoided.

关键词： pediatric hernia likely

Synthesis and characterization of Ce_(0.6)Sr_(0.4)Fe_(0.8)Co_(0.2)O_(3–δ) perovskite material:Potential cathode material for low temperature SOFCs

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Journal of Rare Earths 2017年第4期35卷 389-397页

作者： Mlungisi n.Sithole Bernard Omondi patrick G.ndungu School of Chemistry and Physics University of KwaZulu-NatalWestville CampusPrivate Bag X54001Durban4000South Afrzca Department of Applied Chemistry Doornfontein Campus University of JohannesburgP.O.Box 1701 lDoornfontein 2028JohannesburgSouth.Africa

A sol-gel method and a modified chemical vapour deposition technique were used to produce nanostructured Ce0.6Sr0.4Fe0.8Co0.2O3-δ materials at temperatures as low as 400 ℃. Powders were characterized using Fourier transform infrared spectroscopy （FTIR）, Raman spectroscopy, thermo gravimetric analysis, powder X-ray diffraction （XRD）, scanning electron microscopy （SEM） with energy dispersive X-ray spectroscopy, high resolution transmission electron microscopy （HRTEM）, and nitrogen sorption at 77 K. FTIR spectra showed that the sol-gel method resulted in residual carbon groups on the materials after calcination, while the Raman and XRD analysis confirmed that both synthesis methods resulted in cubic perovskite structure. However, the chemical va- pour deposition （CVD） method resulted in materials with a smaller crystallite size when compared to those prepared via the sol-gel route. The overall morphology of the powders was irregularly shaped aggregated particles as observed by SEM and HRTEM. In addition, HRTEM analysis showed that the materials were highly crystalline. Textural analysis revealed the powders had some mesoporosity, and the surface areas were 76.69 and 65.90 m2/g for materials synthesized using the CVD and sol-gel methods, respectively. The synthesized perovskite powders were used to fabricate button cells employing samarium doped ceria （SDC） as the electrolyte and niO/SDC as the anode materials. As cathode materials, the maximum power density observed was 308.4 mW/cm2 at 500℃.

关键词： nanostructured materials low temperature SOFCs perovskites ceria rare earths

Use of a plane jet for flow-induced noise reduction of tandem rods

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Chinese Physics B 2016年第6期25卷 270-278页

作者：赵鲲杨希祥 patrick n Okolo 张为华 College of Aerospace Science and Engineering National University of Defence Technology Changsha 410073 China Department of Mechanical and Manufacturing Engineering Trinity College Dublin University of Dublin Dublin 2 Dublin Ireland Energy and Power Technology Division Department of Mechanical Engineering University of Nigeria Nsukka Nigeria

Unsteady wake from upstream components of landing gear impinging on downstream components could be a strong noise *** use of a plane jet is proposed to reduce this flow-induced *** rods with different gap widths were utilized as the test *** acoustic and aerodynamic tests were conducted in order to validate this *** test results proved that overall noise emission from tandem rods could be lowered and tonal noise could be removed with use of the plane ***,when the plane jet was turned on,in some frequency range it could be the subsequent main contributor instead of tandem rods to total noise emission whilst in some frequency range rods could still be the main ***,aerodynamic tests fundamentally studied explanations for the noise ***,not only impinging speed to rods but speed and turbulence level to the top edge of the rear rod could be diminished by the upstream plane ***,the vortex shedding induced by the rear rod was reduced,which was confirmed by the speed,Reynolds stress as well as the velocity fluctuation spectral measured in its *** study confirmed the potential use of a plane jet towards landing gear noise reduction.

关键词： plane jet tandem rods flow-induced noise reduction vortex shedding

采用金属镓层氮化技术在石英衬底上生长多晶Gan

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真空科学与技术 2003年第2期23卷 120-122页

作者：邵庆辉叶志镇 nasser n.morgan 顾星黄靖云赵炳辉浙江大学硅材料国家重点实验室杭州310027

随着多晶Gan材料发光研究的不断深入 ,大面积、价格低廉的多晶Gan基光电器件的研制已成为工业生产中一个重要的研究领域。石英玻璃以其自身特有的优势 ,成为生长多晶Gan材料的较为理想的衬底。本文采用一种新的金属镓层氮化技术 ,使用... 详细信息

随着多晶Gan材料发光研究的不断深入 ,大面积、价格低廉的多晶Gan基光电器件的研制已成为工业生产中一个重要的研究领域。石英玻璃以其自身特有的优势 ,成为生长多晶Gan材料的较为理想的衬底。本文采用一种新的金属镓层氮化技术 ,使用无定形石英作衬底 ,在常压下制备出多晶Gan。经分析测试表明 ,生长出的多晶Gan为六方结构且质量较好。

关键词：石英衬底镓层氮化技术金属 Gan 氮化镓半导体多晶材料

HOXB13 and other high penetrant genes for prostate cancer

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Asian Journal of Andrology 2016年第4期18卷 530-532页

作者： patrick G Pilie Veda n Giri Kathleen A Cooney Division of Cancer Medicine The University of Texas MD Anderson Cancer Center Houston TX USA Department of Medical Oncology Sidney Kimmel Cancer Center Thomas Jefferson University Philadelphia PA USA Division of Hematology/ Oncology Department of Internal Medicine University of Michigan Medical School and The University of Michigan Comprehensive Cancer Center Ann Arbor MI USA

Cancer initiation and progression is the result of an accumulation of mutations inkey tumor suppressor genes, mismatch repair genes, or oncogenes, which impact cancer cell growth, death, and differentiation. Mutations occurring in cancer tissue are termed somatic; whereas, heritable mutatons that may be passed onto subsequent generations occur in germline DnA. It is these germline mutations that can lead to cancer family syndromeswhereby family members carrying a deleterious germline mutation have an increased susceptibility to certain cancer phenotypes. Common features of hereditary cancer syndromes include early age-of-onset, multiple affected generations, rare tumor types, and/or multiple primary malignancies.

关键词： @@

DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor

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Journal of Molecular Cell Biology 2019年第9期11卷 725-735页

作者： n.Max Schabla Koushik Mondal patrick C.Swanson Department of Medical Microbiology and Immunology Creighton University2500 California PlazaOmahaNE 68178USA Present address:Institute of Cellular and Molecular Immunology Georg-August-University of GottingenMedical FacultyHumboldtallee 3437073 GottingenGermany Present address:Department of Ophthalmology Hamilton Eye InstituteUniversity of Tennessee Health Sciences Center930 Madison AvenueMemphisTN 38163USA

Cullin-RInG ligases(CRLs)comprise a large group of modular eukaryotic E3 ubiquitin *** this family,the CRL4 ligase(consisting of the Cullin4[CUL4]scaffold protein,the Rbxl RInG finger domain protein,the DnA damage-binding protein 1[DDB1],and one of many DDBl-associated substrate receptor proteins)has been intensively studied in recent years due to its involvement in regulating various cellular processes,its role in cancer development and progression,and its subversion by viral accessory *** discovered as a target for hijacking by the human immunodeficiency virus accessory protein r,the normal targets and function of the CRL4 substrate receptor protein DDBl-Cul4-associated factor 1(DCAF1;also known as VprBP)had remained elusive,but newer studies have begun to shed light on these ***,we review recent progress in understanding the diverse physiological roles of this DCAF1 in supporting various general and cell type-specific cellular processes in its context with the CRL4 E3 ligase,as well as another HECT-type E3 ligase with which DCAF1 also associates,called EDD/*** also discuss emerging questions and areas of future study to uncover the dynamic roles of DCAF1 in normal physiology.

关键词： V(D)J recombination Merlin Dicer p53 EDD/DYRK2 TET Hippo