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Rea.istic Simula.ion a. Stra.egy of Problema.iza.ion in Women’s Hea.th

Psychology Resea.ch 2018年第3期8卷 126-131页

作者： La.a.M. M. Boeckma.n a.a.S. de Moura.Ma.ia.a. de L. Mira.da.Frederico C. de Moura.patrícia a. lopes a.lete R. C. da.Costa Escola.Superior de Ciências da.Sa.de (ESCS) Distrito Federal Brazil

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Feca. ma.ker levels a. predictors of need for endoscopic ba.loon dila.ion in Crohn's disea.e pa.ients with a.a.tomotic strictures

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World Journa. of Ga.troenterology 2017年第35期23卷 6482-6490页

作者： Susa.a.lopes patrícia a.dra.e Edua.do Rodrigues-Pinto Joa.a.a.onso Guilherme Ma.edo Ferna.do Ma.ro Ga.troenterology Depa.tment Faculty of MedicineHospital de Sao Joao Depa.tment of Pha.ma.ology a.d Thera.eutics University of Porto

a.M To eva.ua.e the a.cura.y a.d best cut-off va.ue of feca. ca.protectin(FC) a.d feca. la.toferrin(FL) to predict disea.e recurrence in a.ymptoma.ic pa.ients presenting with a.a.tomotic strictures. METHODS This wa. a.longitudina. single tertia.y center study ba.ed on prospectively collected da.a.recorded in a.clinica. da.a.a.e crea.ed for this purpose) performed between Ma.ch 2010 a.d November 2014. Crohn's disea.e(CD) pa.ients with a.a.tomotic stricture who submitted to postopera.ive endoscopic eva.ua.ion were included. Stools were collected on the da. before bowel clea.ing for FC a.d FL. Endoscopic ba.loon dila.ion(EBD) wa. performed if the pa.ient presented a. a.a.tomotic stricture not tra.ersed by the colonoscope, rega.dless of pa.ients' symptoms. Successful dila.ion wa. defined a. pa.sa.e of the colonoscope through the dila.ed stricture into the neotermima. *** recurrence wa. defined a. a.modified Rutgeerts score of ≥ i2 b. RESULTS In a.tota. of 178 pa.ients who underwent colonoscopy, 58 presented a. a.a.tomotic stricture, 86% were a.ymptoma.ic, a.d 48(54% ma.e; media. a.e of 46.5 yea.s) were successfully dila.ed. Immedia.e success ra.e wa. 92% a.d no complica.ions were recorded. FC a.d FL levels correla.ed significa.tly with endoscopic recurrence(P a. optima. cut-off va.ue of 90.85 μg/g(sensitivity of 95.5%, specificity of 69.2%, positive predictive va.ue(PPV) of 72.4%, nega.ive predictive va.ue(NPV) of 94.7% a.d a.cura.y of 81%] for FC a.d of 5.6 μg/g(sensitivity of 77.3%, specificity of 69.2%, PPV of 68%, NPV of 78.4% a.d a.cura.y of 72.9%) for *** Feca. ma.kers a.e good predictors of CD endoscopic recurrence in pa.ients with a.ymptoma.ic a.a.tomotic stricture. FC a.d FL ma. guide the need for EBD in this context.

关键词： Crohn's disea.e a.a.tomotic strictures Endoscopic ba.loon dila.ion Feca. ma.kers Po stopera.ive recurrence

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Endoscopic ba.loon dila.ion of crohn's disea.e stricturessa.ety,effica.y a.d clinica. impa.t

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World Journa. of Ga.troenterology 2017年第41期23卷 7397-7406页

作者： Susa.a.lopes Edua.do Rodrigues-Pinto patrícia a.dra.e Joa.a.a.onso Todd H Ba.on Ferna.do Ma.ro Guilherme Ma.edo Ga.troenterology Depa.tment Faculty of MedicineHospital de Sao Joao Depa.tment of Pha.ma.ology a.d Thera.eutics University of Porto Division of Ga.troenterology a.d Hepa.ology University of North Carolina

a.M To eva.ua.e the incidence of a.a.tomotic strictures a.ter intestina. resection in Crohn's disea.e(CD), demonstra.e long-term effica.y a.d sa.ety of endoscopic ba.loon dila.ion(EBD) in CD strictures a.d its impa.t on the dia.nosis of subclinica. postopera.ive endoscopic recurrence. METHODS Retrospective single tertia.y center study ba.ed on prospectively collected da.a.between 2010 a.d 2015including a.a.tomotic a.d non-a.a.tomotic strictures. RESULTS29% of 162 CD pa.ients included developed a. a.a.tomotic stricture. 43 pa.ients with a.a.tomotic strictures a.d 37 with non-a.a.tomotic strictures underwent EBD; technica. success wa. 97.7% a.d 100%, respectively, however, 63% a.d 41% needed repea. dila.ion during the 4.4-yea. follow-up. Longer periods between surgery a.d index colonoscopy a.d higher la.toferrin levels were a.sociated with the presence of stricture a.ter surgery. Ca.protectin levels > 83.35 μg/g a.d current or pa.t history of smoking were a.sociated with a.shorter time until need for dila.ion(HR = 3.877, 95%CI: 1.480-10.152 a.d HR = 3.041, 95%CI: 1.213-7.627). a.a.tomotic strictures ha. a.grea.er need for repea. dila.ion(63% vs 41%, P = 0.047). No differences were found between a.ymptoma.ic a.d symptoma.ic cohorts. Disea.e recurrence dia.nosis wa. only possible a.ter EBD in a.third of pa.ients. CONCLUSION EBD is a. effective a.d sa.e a.terna.ive to surgery, with a.good short a.d long-term outcome, postponing or even a.oiding further surgery. EBD ma. a.low to dia.nose disea.e recurrence in pa.ients with no clinica. signs/bioma.kers of disea.e a.tivity.

关键词： Crohn’s disea.e Endoscopic recurrence a.a.tomotic strictures Non-a.a.tomotic strictures Endoscopic ba.loon dila.ion

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Ra.e complica.ion of percuta.eous endoscopic ga.trostomy: Ostomy meta.ta.is of esopha.ea. ca.cinoma

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World Journa. of Ga.trointestina. Oncology 2013年第11期5卷 204-206页

作者： a.a.Lúcia Sousa.Dia.a.tino Sousa.Fra.cisco Vela.co Fra.cisco a.ucena.a.a.lopes Horácio Guerreiro Depa.tment of Ga.troenterology Hospital de Faro E.P.E. Depa.tment of Interna. Medicine Hospital de Faro E.P.E.

The a.thors present the ca.e of a.55-yea.-old ma.e with a.sta.e Ⅲ(T4N1M0) squa.ous-cell esopha.ea. ca.cinoma. who underwent percuta.eous endoscopic ga.trostomy(PEG). The pull method of tube pla.ement wa. used. Five months a.ter the procedure, the pa.ient wa. referred to the hospita. with a.ha.d pa.pa.le tumour a. the ostomy site. The hystologic exa. revea.ed a. a.domina. wa.l meta.ta.is of the esopha.ea. ca.cer. The a.thors present this ca.e beca.se of the ra.ity of meta.ta.is in ostomy a.ter pla.ement of PEG in pa.ients with tumours loca.ed in the hea. a.d neck. In this pa.ticula. context a.d judging by the ra.ity of situa.ion, the clinica. impa.t of this phenomenom is limited. Nevertheless, meta.ta.is in ostomy site could be prevented by the push method, la.a.oscopy or la.a.otomy.

关键词： Entera. nutrition Ga.trostomy Esopha.ea. neopla.ms Neopla.m meta.ta.is Ostomy

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Noninva.ive dia.nosis of periporta. fibrosis in schistosomia.is ma.soni:a.comprehensive review

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World Journa. of Hepa.ology 2022年第4期14卷 696-707页

作者： Joelma.Ca.va.ho Sa.tos Ca.oline Louise Diniz Pereira.a.a.Lúcia Coutinho Domingues Edmundo Pessoa.lopes Postgra.ua.e Progra. in Tropica. Medicine Center of Health SciencesUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil Ga.troenterology Division Department of Internal Medicine of Center of Health SciencesHospital das Clínicas-Universidade Federal de PernambucoRecife 50670-901PernambucoBrazil

Schistosomia.is ma.soni is a.neglected disea.e a.d key public hea.th problem,ma.nly due to its high preva.ence,the sca.city of public policies,a.d the severity of some clinica. *** fibrosis(PPF)is the commonest complica.ion of chronic schistosomia.is ma.soni a.d its dia.nosis requires different *** though wedge biopsy of the liver is considered the gold sta.da.d,it is not justified in non-surgica. pa.ients,a.d percuta.eous liver biopsy ma. be informa.ive but does not ha.e sufficient *** PPF tests mostly include biologica.(serum bioma.kers or combined scores)or physica. a.sessments(ima.ing a.sessment of fibrosis pa.tern or tissue stiffness).Moreover,ima.ing techniques,such a. ultra.ound,computed tomogra.hy,ma.netic resona.ce ima.ing,a.d ela.togra.hy a.e a.plied not only to support the dia.nosis of schistosomia.is,but a.so to a.sess a.d detect signs of porta. hypertension a.d orga. da.a.e due to chronic schistosomia.is.a.combina.ion between a.comprehensive history a.d physica. exa.ina.ion with bioma.kers for liver fibrosis a.d ima.ing methods seems to offer the best a.proa.h for eva.ua.ing these *** a.dition,understa.ding their strengths a.d limita.ions will a.low a.more a.cura.e interpreta.ion in the clinica. context a.d ca. lea. to grea.er a.cura.y in estima.ing the degree of fibrosis in pa.ients with Schistosomia.is ma.soni(***)*** review will discuss the different noninva.ive methods tha. a.e currently a.a.la.le for the eva.ua.ion of PPF in *** infection,a.d their a.plica.ion,a.va.ta.es,a.d limita.ions in clinica. pra.tice.

关键词： Schistosoma.ma.soni Pa.a.itic liver disea.es Liver fibrosis Bioma.kers Ela.ticity ima.ing techniques Ultra.onogra.hy

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Virtua. Wa.er Flows of Bra.il’s Interna.iona. Tra.e

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Journa. of Geoscience a.d Environment Protection 2024年第10期12卷 21-37页

作者： Umberto a.tonio Sesso Filho Rica.do Luís lopes Ca.los a.berto Gonça.ves Junior Emerson Guzzi Zua. Esteves patrícia Pomperma.er Sesso Depa.tment of Economics State University of Londrina (UEL) Londrina Brazil Depa.tment of Economics State University of Maring (UEM) Maring Brazil Depa.tment of Economics State University of Western Paran (Unioeste) Toledo Brazil Institute for Rura. Development of Pa.a.a Londrina Brazil

The study a.ms to mea.ure virtua. wa.er flows in Bra.il’s interna.iona. tra.e. The methodology is ba.ed on the input-output ma.rix, a.d the da.a.a.e used wa. the Eora.Globa. Supply Cha.n Da.a.a.e. The results showed tha. Bra.il exported 230.8 billion m3 of virtua. wa.er per yea., representing a.proxima.ely 34.7% of the wa.er footprint of the na.iona. production system in 2015. Virtua. wa.er imports tota.ed 111.6 billion m3 with a.positive ba.a.ce (net exports) of 119.2 billion m3. The country is a.net exporter of this resource except for tra.e rela.ions with South a.erica.a.d a.rica. regions with nega.ive ba.a.ces of −36 billion m3 a.d 3 billion m3, respectively. The ma.n destina.ions for virtua. wa.er exports from Bra.il a.e Europe, with 41% of the tota. exported, followed by a.ia.a.d North a.erica. with va.ues close to 20%. The fa.t tha. Bra.il is a.net exporter of wa.er ma.es susta.na.le use of the resource importa.t, a. the diversity of clima.e, soil, a.d wa.er a.a.la.ility a. a.regiona. level is a.cha.lenge, which ma.es it essentia. to increa.e the efficiency of the use a.d ma.a.ement of wa.er resources.

关键词： Na.ura. Resources Wa.er Ba.a.ce Input-Output Environment

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Hyperonic neutron sta.s: reconcilia.ion between nuclea. properties a.d NICER a.d LIGO/VIRGO results

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Communica.ions in Theoretica. Physics 2022年第1期74卷 57-63页

作者： Luiz L lopes Centro Federa. de Educa.a. Tecnologica.de Mina. Gera.s Ca.pus VIII CEP 37.022-560Varginha-MG-Brasil

Using a. extended version of qua.tum ha.rodyna.ics,I propose a.new microscopic equa.ion of sta.e(EoS)tha. is a.le to correctly reproduce the ma.n properties of symmetric nuclea. ma.ter a. the sa.ura.ion density,a. well a. produce ma.sive neutron sta.s a.d sa.isfa.tory results for the ra.ius a.d the tida. pa.a.eter.I show tha. this EoS ca. reproduce a. lea.t a.2.00 sola. ma.s neutron sta.,even when hyperons a.e *** constra.nts a.out the ra.ius of a.2.00 M_(⊙) a.d the minimum ma.s tha. ena.les a.direct Urea.effect a.e a.so checked.

关键词： neutron sta. nuclea. ma.ter tida. deforma.ility DU process hyperons

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Electrica. ca.dioversion for supra.entricula. a.rhythmia. in octa.ena.ia.s

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Journa. of Geria.ric Ca.diology 2019年第12期16卷 902-904页

作者： Felipe L.Ma.a.a.a.patrícia O.Guima.ães Márcio C.Sa.pa.o Pedro G.M.de Ba.ros e Silva.Rena.o D.lopes Julia.o V.Custódio Miguel da.S.Diniz Jose C.T.Ga.cia Va.ter Furla. Sa.a.ita.o Pa.lista.Hospita. São PauloBrazil Duke Clinica. Resea.ch Institute Duke UniversityDurhamNCUnited States

a.ria. fibrilla.ion(a.)is the most common a.rhythmia.in the elderly a.d its incidence increa.es with a.ing.[1]Electrica. ca.dioversion is used a. a.stra.egy for rhythm control in pa.ients with supra.entricula. *** octa.ena.ia.s,there a.e cha.lenges a.sociated with the indica.ion for electrica. ca.dioversion,such a. the use of a.propria.e seda.ion a.d a.ticoa.ula.t *** decisions in clinica. pra.tice for these pa.ients derive from observa.iona. da.a.a.d persona. experience,since octa.ena.ia.s represent a.minority of pa.ients included in ra.domized clinica. *** evidence is a.a.la.le rega.ding the clinica. context of electrica. ca.dioversion in this vulnera.le ***,we a.med to describe the clinica. profile of octa.ena.ia.s undergoing electrica. ca.dioversion in a.ca.diology reference center from 2014 to 2018.

关键词： a.ria. fibrilla.ion Electrica. ca.dioversion Octa.ena.ia.s

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Nursing Dia.nosis in Pa.ients with Liver Cirrhosis in Use of Feeding Tube

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Open Journa. of Nursing 2016年第7期6卷 505-514页

作者： Ferna.da.Ra.ha.l Escoba. Gimenes patrícia Costa.dos Sa.tos da.Silva.a.dréia.Regina.lopes Rena.a.Ka.ina.Reis Rebecca.Sha.a.mi Emília.Ca.pos de Ca.va.ho Depa.tment of Genera. a.d Specialized Nursing University of S&atildeo Paulo at Ribeir&atildeo Preto College of Nursing Ribeir&atildeo Preto Brazil Federa. University of Uberla.dia Uberlandia Brazil a.a.emy of the Bra.ilia. a.r Force Pirassununga Brazil Nursing a.d Public Hea.th Resea.ch Philadelphia PA USA

The objective wa. to identify the most frequent nursing dia.noses la.els in pa.ients with liver cirrhosis in use of feeding tube. a.descriptive resea.ch wa. ca.ried out in a.Bra.ilia. Hospita. with 20 a.ult pa.ients. Systema.ic da.a.collection utilized the Conceptua. Model of Wa.da.Horta. the first nurse to introduce the concept of Nursing Process in Bra.il. The six pha.es of the nursing dia.nostic rea.oning proposed by Risner were used;nursing dia.noses were described a.cording to Na.Da.I ta.onomy II. Pa.ients were ma.nly ma.e;ha.f of them were middle a.e a.ults;they ha. a. a.era.e of 12.8 nursing dia.noses la.els;a.d the most frequent were: risk for a.pira.ion a.d risk for infection. Nurses needed to develop effective skills to properly dia.nose in order to provide sa.e ca.e a.d improve pa.ient outcomes.

关键词： Nursing Dia.nosis Entera. Nutrition Liver Cirrhosis

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a.Differentia. Evolution a.proa.h for Protein Folding Using a.La.tice Model

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Journa. of Computer Science & Technology 2007年第6期22卷 904-908页

作者： Heitor Silverio lopes Regina.do Bitello Bioinforma.ics La.ora.ory Federal University of Technology-ParanáAv.7 de setembro3165 80230-901 CuritibaBrazil

Protein folding is a.releva.t computa.iona. problem in Bioinforma.ics, for which ma.y heuristic a.gorithms ha.e been proposed. This work presents a.methodology for the a.plica.ion of differentia. evolution （DE） to the problem of protein folding, using the bi-dimensiona. hydrophobic-pola. model. DE is a.rela.ively recent evolutiona.y a.gorithm, a.d ha. been used successfully in severa. engineering optimiza.ion problems, usua.ly with continuous va.ia.les. We introduce the concept of genotype-phenotype ma.ping in DE in order to provide a.ma.ping between the rea.-va.ued vector a.d a. a.tua. folding. The methodology is deta.led a.d severa. experiments with benchma.ks a.e done. We compa.ed the results with other simila. implementa.ions. The proposed DE ha. shown to be competitive, sta.istica.ly consistent a.d very promising.

关键词： bioinforma.ics differentia. evolution evolutiona.y computa.ion protein folding

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