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Signal Transduction and Targeted Therapy 2023年第1期8卷 10-12页

作者： Rayhane Nchioua Federica Diofano Sabrina Noettger pascal von maltitz Steffen Stenger Fabian Zech Jan Münch Konstantin M.J.Sparrer Steffen Just Frank Kirchhoff Institute of Molecular Virology Ulm University Medical CenterUlmGermany Molecular Cardiology Department of Internal Medicine IIUlm UniversityUlmGermany Institute of Medical Microbiology and Hygiene Ulm University Medical CenterUlmGermany

Dear Editor,Since its first description in South Africa in November 2021,the SARS-CoV-2 Omicron variant rapidly outcompeted the previously dominating Delta *** is the fifth variant of concern(VOC).It contains an unusually high number of mutations compared to previous VOCs,especially in the viral Spike protein,and shows high transmissibility and efficient escape of neutralizing antibodies.

关键词： Strong neutral Omi

Demonstrating grating-based phase-contrast imaging of laser-driven shock waves

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Matter and Radiation at Extremes 2024年第4期9卷 90-97页

作者： Leonard Wegert Stephan Schreiner Constantin Rauch Bruno Albertazzi Paulina Bleuel Eric Frojdh Michel Koenig Veronika Ludwig Artem SMartynenko pascal Meyer Aldo Mozzanica Michael Müller Paul Neumayer Markus Schneider Angelos Triantafyllidis Bernhard Zielbauer Gisela Anton Thilo Michel Stefan Funk Plasma Physics Department GSI Helmholtzzentrum fur SchwerionenforschungPlanckstraBe 164291 DarmstadtGermany Erlangen Centre for Astroparticle Physics(ECAP) Friedrich-Alexander-Universität Erlangen-NurnbergNikolaus-Fiebiger-StraBe 291058 ErlangenGermany LULI-CNRS CEASorbonne UniversitésEcole PolytechniqueInstitut Polytechnique de ParisF-91120 Palaiseau CedexFrance Paul Scherrer Institut(Psi) Forschungsstrasse 1115232VilligenSwitzerland Karlsruhe Institute of Technology Institute of Microstructure TechnologyHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany

Single-shot X-ray phase-contrast imaging is used to take high-resolution images of laser-driven strong shock *** a two-grating Talbot interferometer,we successfully acquire standard absorption,differential phase-contrast,and dark-field images of the shocked *** agreement is demonstrated between experimental data and the results of two-dimensional radiation hydrodynamics simulations of the laser-plasma *** main sources of image noise are identified through a thorough assessment of the interferometer’s *** acquired images demonstrate that grating-based phase-contrast imaging is a powerful diagnostic tool for high-energy-density *** addition,we make a novel attempt at using the dark-field image as a signal modality of Talbot interferometry to identify the microstructure of a foam target.

关键词： interaction shock phase

Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma

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World Journal of Gastroenterology 2014年第17期20卷 4994-4999页

作者： Frank Serge Lehmann Francesca Trapani Ida Fueglistaler Luigi Maria Terracciano Markus von Flüe Gieri Cathomas Andreas Zettl pascal Benkert Daniel Oertli Christoph Beglinger Division of Gastroenterology and Hepatology University Hospital4031 BaselSwitzerland Institute of Pathology University Hospital4003 BaselSwitzerland St.Clara Hospital 4016 BaselSwitzerland Institute of Pathology University Hospital4410 LiestalSwitzerland Institute of Pathology Viollier AG4002 BaselSwitzerland Clinical Trial Unit University Hospital4031 BaselSwitzerland Department of Surgery University Hospital4031 BaselSwitzerland

AIM: To determine calprotectin release before and after colorectal cancer operation and compare it to tumor and histopathological parameters.

关键词： Calprotectin Colorectal cancer Inflammation Tumor size Granulocytes

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Molecular Plant 2012年第1期5卷 115-130页

作者： Stefanie Ranf Julia Grimmer Yvonne P6schl pascal Pecher Delphine Chinchilla Dierk Scheel Justin Lee Leibniz Institute of Plant Biochemistry Stress and Developmental Biology Weinberg 3 D-06120 Halle Germanyb Present address： Institute of Biochemistry and Biotechnology Martin Luther University Halle-Wittenberg Weinbergweg 22 D-06120 Halle Germany Institute of Computer Science Martin Luther University Halle-Wittenberg Von-Seckendorff-Platz 1 D-06120 Halle Germany Zurich-Basel Plant Science Center Botanical Institute University of Basel Hebelstrasse 1 4056 Basel Switzerland

Calcium acts as a second messenger for signaling to a variety of stimuli including MAMPs （Microbe-Associated Molecular Patterns）, such as fig22 and elf18 that are derived from bacterial flagellin and elongation factor Tu, respectively. Here, Arabidopsis thaliana mutants with changed calcium elevation （cce） in response to fig22 treatment were isolated and characterized. Besides novel mutant alleles of the fig22 receptor, FLS2 （Flagellin-Sensitive 2）, and the receptor-associated kinase, BAK1 （Brassinosteroid receptor 1-Associated Kinase 1）, the new cce mutants can be categorized into two main groups--those with a reduced or an enhanced calcium elevation. Moreover, cce mutants from both groups show differ- ential phenotypes to different sets of MAMPs. Thus, these mutants will facilitate the discovery of novel components in early MAMP signaling and bridge the gaps in current knowledge of calcium signaling during plant-microbe interactions. Last but not least, the screening method is optimized for speed （covering 384 plants in 3 or 10 h） and can be adapted to genetically dissect any other stimuli that induce a change in calcium levels.

关键词： Calcium signaling/transport defense responses plant-microbe interactions signal transduction Arabidopsis.

On the combined effect of soil fertility and topography on tree growth in subtropical forest ecosystems—a study from SE China

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Journal of Plant Ecology 2017年第1期10卷 111-127页

作者： Thomas Scholten Philipp Goebes Peter Kühn Steffen Seitz Thorsten Assmann Jürgen Bauhus Helge Bruelheide Francois Buscot Alexandra Erfmeier Markus Fischer Werner Härdtle Jin-Sheng He Keping Ma pascal A.Niklaus Michael Scherer-Lorenzen Bernhard Schmid Xuezheng Shi Zhengshan Song Goddert von Oheimb Christian Wirth Tesfaye Wubet Karsten Schmidt Department of Geosciences Soil Science and GeomorphologyUniversity of TübingenRümelinstraße 19-2372070 TübingenGermany Institute of Ecology Leuphana University LüneburgScharnhorststr.121335 LüneburgGermany Faculty of Forest and Environmental Sciences SilvicultureUniversity of FreiburgTennenbacherstraße 479085 Freiburg im BreisgauGermany Institute of Biology/Geobotany and Botanical Garden Martin Luther University Halle WittenbergAm Kirchtor 106108 HalleGermany German Centre for Integrative Biodiversity Research(iDiv)Halle-Jena-Leipzig Deutscher Platz 5e04103 LeipzigGermany Helmholtz Centre for Environmental Research UFZ Theodor-Lieser-Straße 406120 HalleGermany Department of Plant Sciences University of BernAltenbergrain 213013 BernSwitzerland Peking University No.5 Yiheyuan RoadHaidian DistrictBeijing 100871China Institute of Botany Chinese Academy of SciencesNo.20 NanxincunXiangshanBeijing 100093China Institute of Evolutionary Biology and Environmental Studies University of ZürichWinterthurerstrasse 1908057 ZürichSwitzerland Faculty of Biology Department of GeobotanyUniversity of FreiburgSchänzlestraße 179104 FreiburgGermany Institute of Soil Science Chinese Academy of SciencesNo.71 East Beijing RoadNanjingChina TU Dresden Biodiversity and Nature ConservationPienner Straße 701737 TharandtGermany Department of Systematic Botany and Functional Biodiversity University of LeipzigJohannisallee 2104103 LeipzigGermany

Aims The aim of our research was to understand small-scale effects of topography and soil fertility on tree growth in a forest biodiversity and ecosystem functioning(BEF)experiment in subtropical SE *** Geomorphometric terrain analyses were carried out at a spatial resolution of 5×5 *** samples of different depth increments and data on tree height were collected from a total of 566 plots(667 m2 each).The soils were analyzed for carbon(soil organic carbon[SOC]),nitrogen,acidity,cation exchange capacity(CEC),exchangeable cations and base saturation as soil fertility *** plots were classified into geomorphological *** of variance and linear regressions were applied to all terrain,soil fertility and tree growth *** Findings In general,young and shallow soils and relatively small differences in stable soil properties suggest that soil erosion has truncated the soils to a large extent over the whole area of the *** explains the concurrently increasing CEC and SOC stocks downslope,in hollows and in ***,colluvial,carbon-rich sediments are missing widely due to the convexity of the footslopes caused by uplift and removal of eroded sediments by adjacent *** results showed that soil fertility is mainly influenced by ***-Carlo flow accumulation(MCCA),curvature,slope and aspect significantly affected soil ***,soil fertility was affected by the different geomorphological positions on the experimental sites with ridge and spur positions showing lower exchangeable base cation contents,especially potassium(K),due to *** geomorphological effect of soil fertility is most pronounced in the topsoil and decreases when considering the subsoil down to 50 cm *** soil fertility attributes affect tree height after 1-2 years of growth,among which C stocks proved to be most important while pH_(KCl)and CEC only played minor ***,soil acidity and a hig

关键词： soil fertility topography soil erosion matter transport biodiversity DSM carbon stocks tree forest BEF-China China

Factors Predicting Progression to Severe COVID-19: A Competing Risk Survival Analysis of 1753 Patients in Community Isolation in Wuhan, China

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Engineering 2022年第6期8卷 99-106页

作者： Simiao Chen Hui Sun Mei Heng Xunliang Tong pascal Geldsetzer Zhuoran Wang Peixin Wu Juntao Yang Yu Hu Chen Wang Till Bärnighausen Chinese Academy of Medical Sciences&Peking Union Medical College Beijing 100730China Heidelberg Institute of Global Health(HIGH) Faculty of Medicine and University HospitalHeidelberg UniversityHeidelberg 69120Germany Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Pulmonary and Critical Care Medicine Beijing HospitalBeijing 100730China National Center of Gerontology Institute of Geriatric MedicineBeijing 100730China Division of Primary Care and Population Health Department of MedicineStanford UniversityStanfordCA 94305USA Peking Union Medical College Hospital Beijing 100730China State Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China National Clinical Research Center for Respiratory Diseases Beijing 100029China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina–Japan Friendship HospitalBeijing 100029China

Most studies of coronavirus disease 2019(COVID-19)progression have focused on the transfer of patients within secondary or tertiary care hospitals from regular wards to intensive care *** is known about the risk factors predicting the progression to severe COVID-19 among patients in community iso-lation,who are either asymptomatic or suffer from only mild to moderate *** a multivari-able competing risk survival analysis,we identify several important predictors of progression to severe COVID-19—rather than to recovery—among patients in the largest community isolation center in Wuhan,China from 6 February 2020(when the center opened)to 9 March 2020(when it closed).All patients in community isolation in Wuhan were either asymptomatic or suffered from mild to moderate COVID-19 *** performed competing risk survival analysis on time-to-event data from a cohort study of all COVID-19 patients(n=1753)in the isolation *** potential predictors we inves-tigated were the routine patient data collected upon admission to the isolation center:age,sex,respira-tory symptoms,gastrointestinal symptoms,general symptoms,and computed tomography(CT)scan *** main outcomes were time to severe COVID-19 or *** factors predicting progression to severe COVID-19 were:male sex(hazard ratio(HR)=1.29,95%confidence interval(CI)1.04–1.58,p=0.018),young and old age,dyspnea(HR=1.58,95%CI 1.24–2.01,p<0.001),and CT signs of ground-glass opacity(HR=1.39,95%CI 1.04–1.86,p=0.024)and infiltrating shadows(HR=1.84,95%CI 1.22–2.78,p=0.004).The risk of progression was found to be lower among patients with nausea or vomiting(HR=0.53,95%CI 0.30–0.96,p=0.036)and headaches(HR=0.54,95%CI 0.29–0.99,p=0.046).Our results suggest that several factors that can be easily measured even in resource-poor set-tings(dyspnea,sex,and age)can be used to identify mild COVID-19 patients who are at increased risk of disease *** for CT signs of ground-glass opacity and i

关键词： COVID-19 Asymptomatic and mild Community isolation Fangcang shelter hospital Competing risk survival analysis

当前围手术期处理模式:北欧五国结直肠外科医生调查

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英国医学杂志中文版 2005年第6期8卷 339-341页

作者： Kristoffer Lassen pascal Hannemann Olle Ljungqvist Ken Fearon Cornelis H C Dejong Maarten F von Meyenfeldt Jonatan Hausel Jonas Nygren Jens Andersen Arthur Revhaug 王东 Department of Gastrointestinal Surgery University Hospital of Northern Norway9038TromsφNorway Department of Surgery University Hospital MaastrichtMaastricht6202AZNetherlands Centre for Surgical Sciences Division of SurgeryKarolinska University HospitalStockholmSweden Clinical and Surgical Sciences(Surgery) School of Clinical Sciences and Community HealthUniversity of EdinburghEdinburgh EH16 4SAprofessor of surgery Department of Surgical Gastroenterology 435 Hvidovre University HospitalHvidovre 2650Denmark

有关结直肠外科围手术期最佳治疗的证据是很充足的.通过术后进食、静脉适量输液以及减少神经内分泌系统的应激反应,可以抑制术后分解代谢,同时促进患者的康复.术前肠道准备和术后胃肠减压这些特别措施已不作为常规,而改为术后持续硬膜... 详细信息

有关结直肠外科围手术期最佳治疗的证据是很充足的.通过术后进食、静脉适量输液以及减少神经内分泌系统的应激反应,可以抑制术后分解代谢,同时促进患者的康复.术前肠道准备和术后胃肠减压这些特别措施已不作为常规,而改为术后持续硬膜外麻醉、限制静脉输液和补钠、术后第1天开始即允许经口自由进食1-5等.本项调查的目的是了解北欧五国(苏格兰、荷兰、丹麦、瑞典和挪威)在结直肠癌手术围手术期治疗方面的特点.

关键词：围手术期处理结直肠外科医生北欧神经内分泌系统持续硬膜外麻醉术后进食外科围手术期术后胃肠减压术前肠道准备

3D-printed facet-attached microlenses for advanced photonic system assembly

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Light(Advanced Manufacturing) 2023年第2期4卷 1-17页

作者： Yilin Xu pascal Maier Mareike Trappen Philipp-Immanuel Dietrich Matthias Blaicher Rokas Jutas Achim Weber Torben Kind Colin Dankwart Jens Stephan Andreas Steffan Amin Abbasi Padraic Morrissey Kamil Gradkowski Brian Kelly Peter O’Brien Wolfgang Freude Christian Koos Institute of Photonics and Quantum Electronics(IPQ) Karlsruhe Institute of Technology(KIT)Engesserstr.576131 KarlsruheGermany Institute of Microstructure Technology(IMT) KITHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany Vanguard Automation GmbH Gablonzer Strasse.1076185 KarlsruheGermany ficon TEC Service GmbH Im Finigen 328832 AchimGermany II-VI Inc. Reuchlinstraße 10/1110553 BerlinGermany Photonics Research Group Ghent University-imecTechnologiepark-Zwijnaarde 126B-9052 GentBelgium Tyndall National Institute T12 R5CP CorkIreland Eblana Photonics Ltd. West Pier Business Campus3 Old Dunleary RdDún LaoghaireDublinA96 A621Ireland

Wafer-level mass production of photonic integrated circuits(PIC)has become a technological mainstay in the field of optics and photonics,enabling many novel and disrupting a wide range of existing ***,scalable photonic packaging and system assembly still represents a major challenge that often hinders commercial adoption of PIC-based ***,chip-to-chip and fiber-to-chip connections often rely on so-called active alignment techniques,where the coupling efficiency is continuously measured and optimized during the assembly *** unavoidably leads to technically complex assembly processes and high cost,thereby eliminating most of the inherent scalability advantages of PIC-based *** this paper,we demonstrate that 3D-printed facet-attached microlenses(FaML)can overcome this problem by opening an attractive path towards highly scalable photonic system assembly,relying entirely on passive assembly techniques based on industry-standard machine vision and/or simple mechanical *** can be printed with high precision to the facets of optical components using multi-photon lithography,thereby offering the possibility to shape the emitted beams by freely designed refractive or reflective ***,the emitted beams can be collimated to a comparatively large diameter that is independent of the device-specific mode fields,thereby relaxing both axial and lateral alignment ***,the FaML concept allows to insert discrete optical elements such as optical isolators into the free-space beam paths between PIC *** show the viability and the versatility of the scheme in a series of selected experiments of high technical relevance,comprising pluggable fiber-chip interfaces,the combination of PIC with discrete micro-optical elements such as polarization beam splitters,as well as coupling with ultra-low back-reflection based on non-planar beam paths that only comprise tilted optical *** on our re

关键词： Photonic integration Photonic assembly Photonic packaging Additive laser manufacturing Multi-photon lithography Facet-attached microlenses Optical alignment tolerances Fiber-chip coupling Hybrid multi-chip modules

Fluctuating temperature modifies heat-mortality association around the globe

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The Innovation 2022年第2期3卷 65-72页

作者： Yao Wu Bo Wen Shanshan Li Antonio Gasparrini Shilu Tong Ala Overcenco Ales Urban Alexandra Schneider Alireza Entezari Ana Maria Vicedo-Cabrera Antonella Zanobetti Antonis Analitis Ariana Zeka Aurelio Tobias Barrak Alahmad Ben Armstrong Bertil Forsberg CarmenÍñiguez Caroline Ameling César De la Cruz Valencia ChristoferÅström Danny Houthuijs Do Van Dung Dominic Royé Ene Indermitte Eric Lavigne Fatemeh Mayvaneh Fiorella Acquaotta Francesca de’Donato Francesco Sera Gabriel Carrasco-Escobar Haidong Kan Hans Orru Ho Kim Iulian-Horia Holobaca Jan Kyselý Joana Madureira Joel Schwartz Klea Katsouyanni Magali Hurtado-Diaz Martina SRagettli Masahiro Hashizume Mathilde pascal Micheline de Sousa Zanotti Stagliorio Coélho Noah Scovronick Paola Michelozzi Patrick Goodman Paulo Hilario Nascimento Saldiva Rosana Abrutzky Samuel Osorio Tran Ngoc Dang Valentina Colistro Veronika Huber Whanhee Lee Xerxes Seposo Yasushi Honda Michelle L.Bell Yuming Guo Department of Epidemiology and Preventive Medicine School of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Climate Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Department of Public Health Environments and SocietyLondon School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre for Statistical Methodology London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre on Climate Change&Planetary Health London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Shanghai Children’s Medical Centre Shanghai Jiao Tong UniversityShanghai 200025China School of Public Health Institute of Environment and Human HealthAnhui Medical UniversityHefei 230032China Center for Global Health Nanjing Medical UniversityNanjing 211166China School of Public Health and Social Work Queensland University of TechnologyBrisbane 4000Australia National Agency for Public Health of the Ministry of Health Labour and Social Protection of the Republic of MoldovaChisinau MD-2009Republic of Moldova Institute of Atmospheric Physics Czech Academy of SciencesPrague 14100Czech Republic Faculty of Environmental Sciences Czech University of Life SciencesPrague 16500Czech Republic Institute of Epidemiology Helmholtz Zentrum M€unchen-German Research Center for Environmental HealthNeuherberg 85747Germany Faculty of Geography and Environmental Sciences Hakim Sabzevari UniversitySabzevar ***Iran Institute of Social and Preventive Medicine University of BernBern 3012Switzerland Oeschger Center for Climate Change Research University of BernBern 3012Switzerland Department of Environmental Health Harvard T.H.Chan School of Public HealthHarvard UniversityBostonMA 02115USA Department of Hygiene Epidemiology and Medical StatisticsNational and Kapodistrian University of AthensAthens 11527Greece Institute for Environment Healthand SocietiesBrunel University LondonLondon UB83PNUK Institute of Environmental Assessment and

Studies have investigated the effects of heat and temperature variability(TV)on ***,few assessed whether TV modifies the heat-mortality *** on daily temperature and mortality in the warm season were collected from 717 locations across 36 *** was calculated as the standard deviation of the average of the same and previous days’minimum and maximum temperatures.

关键词： deviation modif heat

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO