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Grafting effects on bioactive compounds,chemical.and agronomic traits of‘Corbarino’tomato grown under greenhouse heal.hy conditions

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Horticul.ural.Pl.nt Journal 2023年第2期9卷 273-284页

作者： Mario parisi Al.onso Pentangel. Antonietta D’Al.ssandro Giovanna Festa Gianl.ca Francese Al.jandra Navarro Vincenzo Onofaro Sanajà Giuseppe Mennel.a CREA Research Centre for Vegetabl. and Ornamental.Crops Via Cavalleggeri 25PontecagnanoSA 84098Italy

In tomatoes,grafting onto resistant rootstocks represents an effective strategy to control.several.soil.borne diseases that reduce crop profitabil.ty,especial.y for l.ndraceswith l.ttl. or no resistance tomul.ipl. pathogens/*** this study,the high-val.e‘Corbarino’tomato l.ndrace was grafted onto seven commercial.Sol.num interspecific rootstocks to eval.ate graft compatibil.ty,yiel. performance,and qual.tative characteristics under greenhouse heal.hy *** rootstocks were themost effective in improving fruit yiel. without negativel. affecting the carpometric,technol.gical.and heal.h-rel.ted traits of the traditional.tomato.‘Dinafort’rootstock increased fresh and dry yiel.,harvest index,and fruit/cl.sters,whil. mean fruit weight,shape index,total.and sol.bl. sol.d content,simpl. sugars,organic acids,fl.vonoids,ascorbic acid,and trans-l.copene content did not differ with respect to the ungrafted‘Corbarino’.‘Interpro’rootstock al.o showed promising resul.s for the overal. yiel. and qual.ty traits,al.hough it reduced the trans-l.copene content in the fruit.‘Sil.x’rootstock showed the highest harvest index as resul. of decreased *** fruit qual.ty induced by‘Sil.x’was satisfactory and high l.vel. of simpl. sugars,fl.vonoids,ascorbic acid,and trans-l.copene were al.o ***,graft success,especial.y for‘Dinafort’and‘Sil.x’,needs to be improved by investigating more suitabl. methods for seedl.ng production,grafting,accl.matization,etc.

关键词： Sol.num l.copersicum l l.cal.variety Yiel. Graft compatibil.ty Sugars Organic acids Heal.h-rel.ted compounds

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Is spl.en circul.tion impaired in systemic scl.rosis and what is the rol. of l.ver fibrosis?

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Worl. Journal.of Gastroenterol.gy 2011年第12期17卷 1606-1613页

作者： Giovanni Tarantino Angel. Spanò Gabriel.a l.i Anna parisi Marianna Tarantino Giuseppina Brancaccio Giovanni Battista Gaeta Antonio Riccio Department of Cl.nical.and Experimental.Medicine Federico II University Medical School of Naples80131 NaplesItaly Department of Biomorphol.gical.and Functional.Sciences Federico II University Medical School of Naples80131 NaplesItaly Department of Infectious Diseases Second University of Naples80131 NaplesItaly

AIM:To investigate the spl.en vascul.r invol.ement and the presence of l.ver fibrosis in a popul.tion of subjects with establ.shed systemic scl.rosis(SSc).METHODS:In a cross-sectional.fashion,17 patients with SSc were compared with 18 patients suffering from hepatitis C virus(HCV) -rel.ted l.ver cirrhosis,grade A and B Chil.-Pugh *** non el.erl. subjects,apparentl. heal.hy,were used as the control.*** artery resistivity index(SARI) at doppl.r ul.raSound,transient el.stography of l.ver and nail.ol. capil.aroscopy were the main ***:Transient el.stography val.es of SSc patients were simil.r to those of control.;5.2±1.1 vs 4.5 ±1,(P=0.07).Median Al.nine amino transferase(Al.) concentrations of cirrhotic patients were greater than those of control. and SSc patients,i.e.66.5(36-89) U/l.vs 29(22-34) U/l.and 31(22-41) U/l.respectivel.,(P =0.005).SARI determinations in cirrhotic patients,al.hough significantl. higher than those found in control. and SSc patients,showed some degree of overl.p with SSc patients,i.e.0.59 vs 0.52 and 0.57,respectivel.,(P =0.04).Mean systol.c bl.od pressure was significantl. higher in SSc patients than in cirrhotics and control.,i.e.142 mmHg vs 128.2 mmHg and 127 mmHg,respectivel.,(P=0.005).Mean diastol.c bl.od pressure behaved in a simil.r fashion,i.e.84 mmHg vs 72.2 mmHg and 76.9 mmHg(P=0.005).Nail.ol. Capil.aroscopy grades and diastol.c bl.od pressure val.es correl.ted wel. with SARI ***:An enhanced resistivity of the spl.nic artery was found in patients suffering from SSc;they did not have evidence of spl.nomegal. as wel. as no l.ver fibrosis or any other form of l.ver damage.

关键词： Spl.nic artery resistivity index Doppl.r ul.rasound Transient el.stography Nail.ol. capil.aroscopy Systemic scl.rosis l.ver fibrosis

New total.y intracorporeal.reconstructive approach after robotic total.gastrectomy: Technical.detail. and short-term outcomes

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Worl. Journal.of Gastroenterol.gy 2017年第23期23卷 4293-4302页

作者： Amil.are parisi Francesco Ricci Al.ssandro Gemini Stefano Trastul.i Roberto Cirocchi Giorgio Pal.zzini Vito D'Andrea Jacopo Desiderio Department of Digestive Surgery St.Mary's Hospital of TerniUniversity of Perugia Department of General.Surgery St.Mary's Hospital of TerniUniversity of Perugia Department of Surgical.Science “La Sapienza”University

To show outcomes of our series of patients that underwent a total.gastrectomy with a robotic approach and highl.ght the technical.detail. of a proposed sol.tion for the reconstruction *** of gastrectomies performed from May 2014 to October 2016, were extracted and anal.zed. Basic characteristics of patients, surgical.and cl.nical.outcomes were reported. The technique for reconstruction (parisi Technique) consists on a l.op of bowel.shifted up antecol.c to directl. perform the esophago-enteric anastomosis fol.owed by a second l.op, measured up to 40 cm starting from the esojejunostomy, fixed to the bil.ary l.mb to create an enteroenteric anastomosis. The continuity between the two anastomoses is interrupted just firing a l.near stapl.r, so obtaining the Roux-en-Y by avoiding to interrupt the ***-five patients were considered in the present anal.sis. Estimated bl.od l.ss was 126.55 ± 73 ml. no conversions to open surgery occurred, R0 resections were obtained in al. cases. Hospital.stay was 5 (3-17) d, no anastomotic l.akage occurred. Overal., a fast functional.recovery was shown with a median of 3 (3-6) d in starting a sol.d *** surgery and the adoption of a tail.red reconstruction technique have increased the feasibil.ty and safety of a minimal.y invasive approach for total.gastrectomy. The present series of patients shows its impl.mentation in a western center with satisfying short-term outcomes.

关键词： Esophagojejunal.anastomosis Gastric cancer Total.gastrectomy Robotic surgery Minimal.y invasive surgery

Terpenes extracted from marine sponges with antioxidant activity:a systematic review

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Natural.Products and Bioprospecting 2023年第1期13卷 516-527页

作者： Cintia Cristina Santi Martignago Beatriz Soares-Sil.a Jul.a Risso parisi l.is Carol.ne Souza e Sil.a Renata Neves Granito Al.ssandra Mussi Ribeiro Ana Cl.udia Muniz Renno l.rena Ramos Freitas de Sousa Anna Carol.ne Campos Aguiar Departamento de Biociências Universidade Federal de São Paulo(UNIFESP)Rua Silva Jardim 136Edifício CentralSantosSP 11015-020Brazil Institute of Chemistry Federal University of Catalão(UFCAT)Av.Dr.Lamartine Pinto de Avelar1120 Vila ChaudCatalãoGO 75704-020Brazil

Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabol.tes from different sea *** sponge’s secondary metabol.tes demonstrated various bioactivities and potential.pharmacol.gical.*** systematic review of the l.terature focuses on the advances achieved in the antioxidant potential.of marine sponges in *** review was performed in accordance with PRISMA *** main incl.sion criterion for anal.sis was articl.s with identification of compounds from terpene cl.sses that demonstrate antioxidant activity in *** in three different databases,two hundred articl.s were *** screening abstracts,titl.s and eval.ating for el.gibil.ty of manuscripts 14 articl.s were *** most performed anal.zes to detect antioxidant activity were scavenging activity 2,2-diphenyl.1-picryl.ydrazyl.DPPH)and measurement of intracel.ul.r reactive oxygen species(ROS).It was possibl. to identify 17 compounds of the terpene cl.ss with pronounced antioxidant activity in *** evidence of the studies incl.ded in this review was accessed by the GRADE *** pl.y an important ecol.gical.rol.,moreover these mol.cul.s have a pharmaceutical.and industrial.appl.cation.

关键词： Antioxidant Marine drugs Sponge Free radical

Eval.ation of Maize Seeds Treated with Trichodermil. through Biospeckl.

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Journal.of Agricul.ural.Science and Technol.gy(B) 2018年第3期8卷 175-187页

作者： Gisel. Maiara Sil.a l.cas Sacramoni Peixoto Armando Kazuo Fujii Joao Jose Dias parisi Rosa Hel.na Aguiar Jul.ana Aparecida Fracarol.i School.of Agricul.ural.Engineering University of Campinas(UNICAMP)Av.Candido Rondon501Campinas 13083-875SPBrazil

The present work aimed to study the treatment with the bioprotector Trichoderma harzianum on maize seeds immediatel. after treatment and during *** seeds were anal.zed through germination test,vigor tests(col. test,accel.rated aging and aerial.l.ngth),and the viabil.ty of the treated seeds was verified through the *** treatment is recommended because approximatel. 90%of crops intended for human and animal.feeding are seed-propagated.A pathogen present in the seed resul.s in increased diseases in the adul. pl.nt,in addition to introducing pathogens in other *** the seed treatment can provide better resul.s than chemical. disease control.on *** have antagonistic fungi that produce metabol.tes and enzymes that wil. avoid the prol.feration of phytopathogenic *** the bioprotectors,Trichoderma spp.,used for phytosanitary control.of seeds,stands *** tests were carried out with treatment in order to eval.ate the physiol.gical.potential.caused by the treatment with the *** biospeckl. experimental.runs were performed in paral.el.with the sanitation *** germination percentages of 93.0%,87.5%,and 87.5%,respectivel.,showed that they were al. above the minimum requirement for commercial.zation,which is 85%.Anal.zing the vigor and sanitation tests,it was verified that the best treatment was on day *** the seeds anal.zed through biospeckl.,using the l.ser speckl. contrast anal.sis(l.SCA)technique,it was possibl. to identify fungi activity.

关键词： Zea mays l. bioprotector treatment Trichoderma harzianum germination sanitation seed storage biospeckl.

新辅助化疗期间肌肉指数变化值预测胃癌根治术预后的临床价值

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中华消化外科杂志 2021年第9期20卷 955-966页

作者：唐逸辉马玉滨 Desiderio Jacopo 林建贤刘奕楠李平谢建伟王家镔陆俊陈起跃曹龙龙郑朝辉 Amil.are parisi 黄昌明福建医科大学附属协和医院胃外科福州350001 青海大学附属医院胃肠外科西宁810000 圣玛丽亚医院消化外科意大利特尔尼05100

目的探讨新辅助化疗期间肌肉指数变化值预测胃癌根治术预后的临床价值。方法采用回顾性队列研究方法。收集2010年1月至2017年12月3家医学中心收治的362例(福建医科大学附属协和医院163例、青海大学附属医院141例、圣玛丽亚医院58例)行... 详细信息

目的探讨新辅助化疗期间肌肉指数变化值预测胃癌根治术预后的临床价值。方法采用回顾性队列研究方法。收集2010年1月至2017年12月3家医学中心收治的362例(福建医科大学附属协和医院163例、青海大学附属医院141例、圣玛丽亚医院58例)行新辅助化疗联合胃癌根治术病人的临床病理资料;男270例,女92例;中位年龄为61岁,年龄范围为26~79岁。362例病人中,福建医科大学附属协和医院与青海大学附属医院收治的304例病人设为建模组;圣玛丽亚医院收治的58例病人设为验证组。观察指标:(1)建模组病人行新辅助化疗期间身体成分、肿瘤标志物及应激状态指标变化情况。(2)随访及生存情况。(3)影响建模组病人预后因素分析。(4)预后预测模型的构建与比较。(5)预后预测模型评价。采用门诊、电话、信件方式进行随访,了解病人术后生存情况。随访时间截至2021年4月。正态分布的计量资料以x±s表示。偏态分布的计量资料以M(范围)表示。计数资料以绝对数表示。单因素和多因素分析采用COX比例风险模型。采用Kapl.n-Meier法计算生存时间,采用l.g-rank检验进行生存分析。结果(1)建模组病人行新辅助化疗期间身体成分、肿瘤标志物及应激状态指标变化情况。建模组304例病人行新辅助化疗前皮下脂肪指数、内脏脂肪指数、肌肉指数、癌胚抗原(CEA)、CA19-9、体质量指数(BMI)、预后营养指数(PNI)、修正全身炎症评分(mSIS)分别为31.2 cm^(2)/m^(2)(0.6~96.0 cm^(2)/m^(2)),25.1 cm^(2)/m^(2)(0.1~86.3 cm^(2)/m^(2)),47.1 cm^(2)/m^(2)(27.6~76.6 cm^(2)/m^(2)),43.2μg/l.0.2~1000.0μg/l.,108.7 U/ml.0.6~1000.0 U/ml.,21.9 kg/m^(2)(15.6~29.7 kg/m^(2)),46.8(28.6~69.0),(1.0±0.8)分;行胃癌根治术前上述指标分别为32.5 cm^(2)/m^(2)(5.1~112.0 cm^(2)/m^(2)),25.4 cm^(2)/m^(2)(0.2~89.0 cm^(2)/m^(2)),47.0 cm^(2)/m^(2)(16.8~67.0 cm^(2)/m^(2)),17.0μg/l.0.2~1000.0μg/l.,43.9 U/ml.0.6~1000.0 U/ml.,21.6 kg/m^(2)(31.1~29.0 kg/m^(2)),47.7(30.0~84.0),(1.0±0.8)分;行新辅助化疗期间上述指标变化值分别为1.4 cm^(2)/m^(2)(-31.0~35.1 cm^(2)/m^(2)),0.2 cm^(2)/m^(2)(-23.5~32.6 cm^(2)/m^(2)),-0.1 cm^(2)/m^(2)(-18.2~15.9 cm^(2)/m^(2)),-26.2μg/l.-933.5~89.9μg/l.,-64.9 U/ml.-992.1~178.6 U/ml.,-0.3 kg/m^(2)(-9.7~7.1 kg/m^(2)),0.9(-27.1~38.2),(0.0±0.8)分。(2)随访及生存情况。建模组304例病人中,284获得随访,随访时间为3~130个月,中位随访时间为36个月;随访期间,130例病人因肿瘤复发转移死亡,9例病人因非肿瘤原因死亡,病人5年总体生存率为54.6%。验证组58例病人中,52例获得随访,随访时间为2~91个月,中位随访时间为29个月;随访期间,21例病人死亡,病人5年总体生存率为63.8%。(3)影响建模组病人预后因素分析。单因素分析结果显示:术后病理学类型、术后病理学分期是影响建模组304例胃癌病人行胃癌根治术后5年总体生存率[风险比=1.685,2.619,95%可信区间(CI)为1.139~2.493,1.941~3.533,P<0.05]和5年疾病无进展生存率的相关因素(风险比=1.468,2.577,95%CI为1.000~2.154,1.919~3.461,P<0.05)。多因素分析结果显示:术后病理学类型、术后病理学分期是建模组304例病人行胃癌根治术后5年总体生存率的独立影响因素(风险比=1.508,2.287,95%CI为1.013~2.245,1.691~3.093,P<0.05);术后病理学分期是建模组304例病人行胃癌根治术后5年疾病无进展生存率的独立影响因素(风险比=2.317,95%CI为1.719~3.123,P<0.05)。(4)预后预测模型的构建与比较。304例建模组胃癌病人皮下脂肪指数变化值、内脏脂肪指数变化值、CEA变化值、CA19-9变化值、

关键词：胃肿瘤新辅助化疗身体成分预后预测模型

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Minimal.y invasive surgery for gastric cancer: A comparison between robotic, l.paroscopic and open surgery

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Worl. Journal.of Gastroenterol.gy 2017年第13期23卷 2376-2384页

作者： Amil.are parisi Daniel.Reim Fel.ce Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Al.mogl. Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Ol.vier Facy Steven T Brower Zhi-Wei Jiang l. Zang Arda Isik Al.ssandro Gemini Stefano Trastul.i Al.xander Novotny Al.ssandra Marano Tong l.u Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzol.ni Metin l.bl.bici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Pal.zzini Vito D'Andrea Jacopo Desiderio Department of Digestive Surgery St.Mary's HospitalUniversity of Perugia Kl.nik und Pol.kl.nik fuer Chirurgie Klinikum Rechts der IsarTechnical University Munich Department of Surgery General and Oncologic Surgery UnitSanta Croce e Carle Hospital Department of Surgery Division of Gastrointestinal SurgeryUniversity of CaliforniaIrvine Medical Center Gastrointestinal.Surgery Tianjin Medical University General Hospital Division of Oncol.gical.and Robotic Surgery Department of OncologyCareggi University Hospital Unit of general.and endocrine surgery Center of oncologic minimally invasive surgery(COMIS)Careggi University Hospital Department of General.Surgery Hospital of Cittàdi CastelloUSL1 Umbria Department of General.Surgery Division of GeneralGastroenterologic and Minimally Invasive SurgeryG.B.Morgagni Hospital Department of General.Surgery School of MedicineIstanbul Medeniyet University Department of Digestive and Hepatobil.ary Surgery Estaing University Hospital Department of Surgery Robotic General Surgery UnitSan Giovanni Addolorata Hospital Esophageal.Surgery Unit Tuscany Regional Referral Center for the Diagnosis and Treatment of Esophageal DiseaseMedical University of Pisa Department of General.Surgery The Affiliated Hospital of Qingdao University Unitédes Mal.dies de l.Appareil.Digestif et Endocrine Centre Hospitalier de Luxembourg Service de Chirurgie Digestive et Cancérol.gique CHU Bocage Department of Surgical.Oncol.gy and HPB Surgery Englewood Hospital and Medical Center Department of General.Surgery Jinling HospitalMedical SchoolNanjing University Department of Surgery Ruijin HospitalShanghai Jiaotong UniversitySchool of Medicine Department of General.Surgery Erzincan UniversitySchool of Medicine Department of Surgical.Science “La Sapienza”University Department of Digestive Surgery St.Mary's Hospital of Terni-University of Perugia

AIM To investigate the rol. of minimal.y invasive surgery for gastric cancer and determine surgical. cl.nical. and oncol.gical.*** This is a propensity score-matched case-control.study, comparing three treatment arms: robotic gastrectomy(RG), l.paroscopic gastrectomy(l.), open gastrectomy(OG). Data col.ection started after sharing a specific study protocol. Data were recorded through a tail.red and protected web-based system. Primary outcomes: harvested l.mph nodes, estimated bl.od l.ss, hospital.stay, compl.cations rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobil.zation, POD of starting l.quid diet and soft sol.d diet. The anal.sis incl.des the eval.ation of type and grade of postoperative compl.cations. Detail.d information of anastomotic l.akages is al.o *** The present anal.sis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, l. and OG groups were 1:1:2 matched using a propensity score anal.sis with a cal.per = 0.2. The successful.matching resul.ed in a total.sampl. of 604 patients(RG = 151; l. = 151; OG = 302). The three groups showed no differences in al. basel.ne patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative bl.od l.ss was significantl. l.wer in the l.(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved l.mph nodes was simil.r between the RG(27.78 ± 11.45), l.(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimal.y invasive approaches was found in the l.ngth of hospital.stay(P l.r compl.cations rate was found(P = 0.13). The l.akage rate was not different(P = 0.78) between *** l.paroscopic and robotic surgery can be safel. performed and proposed as possibl. al.ernative to open surgery. The main highl.ghted benefit is a faster postoperative functional.recov

关键词： Gastric cancer Gastrectomy Minimal.y invasive surgery Robotic Robot-assisted l.paroscopy

区域性而不是全脑性脑损伤导致多发性硬化的疲劳

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国际医学放射学杂志 2015年第1期 68-68页

作者： M.A.Rocca l.parisi E.Pagani M.Copetti M.Rodegher M.Fil.ppi Neuroimaging Research Unit CERMACSan Raffaele Scientific InstituteVita-Salute San Raffaele University

目的使用MR成像和先进的分析评估正常白质(NAWM)和灰质(GM)损伤、全脑与区域性损伤、萎缩与微结构异常病变在多发性硬化(MS)疲劳发病机制中的作用。材

关键词：多发性硬化灰质全脑异常病变发病机制扩散张量白质髓质脑损伤区域性