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Science China Chemistry 2025年第1期 297-307页

作者： Bin Fang limin Wang Haoqin li Jiaxin Zhang Yang Ding pan pan li Bo Peng Hua Bai lin li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

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Difference and similarity between type A interrupted aortic arch and aortic coarctation in adults:Two case reports

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World Journal of Clinical Cases 2022年第11期10卷 3472-3477页

作者： Si-Xie Ren Qian Zhang pan-pan li Xiao-Dong Wang Department of Radiology Chengdu Second People’s HospitalChengdu 610000Sichuan ProvinceChina Department of Radiology First Hospital of Shanxi Medical UniversityTaiyuan 030000Shanxi ProvinceChina Department of Radiology Sichuan Cancer HospitalChengdu 610000Sichuan ProvinceChina

BACKGROUND Aortic coarctation(CoA)is usually confused with interrupted aortic arch(IAA),especially adult type A interrupted aortic arch,due to their similar anatomical *** the main difference between them is whether arterial lumen exhibits continuity or not,the clinical manifestations are similar and connection exists between *** type A IAA is considered as an extreme form of CoA,which is complete discontinuity of aortic function and lumen caused by degenerative arterial *** paper reports two cases(interrupted aortic arch and severe aortic coarctation)to analyze the difference and similarity between *** SUMMARY The two cases of patients presented with hypertension for many *** tomography angiography showed that the aortic arch and descending aorta were discontinuous or significantly narrowed with extensive collateral *** IAA patient refused surgical treatment and blood pressure could be controlled with *** the CoA patient underwent stent implantation because of uncontrollable hypertension,the blood flow recovered smoothly and the blood pressures at both ends of the stenosis returned to normal after *** Adult type A IAA and CoA have difference and similarity,and type A IAA is associated with CoA to a certain *** treatment method should be chosen based on the patient's clinical symptoms rather than the severity of the lesion.

关键词： Interrupted aortic arch Aortic coarctation Computed tomography Angiogram Case report

Effects of steep-axis incision on corneal curvature in onehanded phacoemulsification

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International Journal of Ophthalmology(English edition) 2019年第8期12卷 1277-1282页

作者： pan-pan li Ye-Meng Huang Qi Cai li-li Huang Yu Song Huai-Jin Guan Department of Ophthalmology Nantong City No.1People’sHospital and Second Affiliated Hospital of Nantong UniversityNantong226000Jiangsu ProvinceChina Department of Ophthalmology Affiliated Hospital of NantongUniversityNantong226000Jiangsu ProvinceChina

AIM: To examine the effects of one-handed phacoemulsification with steep-axis incision on corneal curvature and analyze surgically induced astigmatism(SIA) on the true net power, anterior and posterior corneal surfaces. METHODS: Patients with cataracts underwent onehanded phacoemulsification with a 2.4-mm steep-axis of clear corneal incision(CCI) based on true net power. CCI was created under the guidance of Verion. Central corneal thickness(CCT), keratometry readings of the true net power and anterior and posterior corneal surface were obtained using Pentacam. Biometry, such as axial length, anterior chamber depth(ACD) and white-to-white(WTW) were performed using Lenstar pre-and 3 mo postoperatively. RESULTS: The study evaluated 68 eyes of 65 patients. The mean age was 65.93±9.40 y;CCT was 529.21±37.40 μm;WTW was 11.59±0.35 mm. Regarding true net power, keratometric value at the flattest corneal meridian for the 3-mm central zone(Ks) was significantly decreased postoperatively(P=0.031). Keratometric value at the steepest corneal meridian for the 3-mm central zone(Kf) was increased postoperatively(P>0.05). Astigmatism of true net power was 1.21±0.56 D preoperatively and significantly decreased to 1.02±0.58 D postoperatively(P=0.021). On the anterior corneal surface, no significant difference in Ks and Kf was noted pre-versus postoperatively. Anterior corneal astigmatism was 1.08±0.51 D preoperativelyand significantly decreased to 0.87±0.46 D postoperatively(P=0.002). On the posterior corneal surface, Ks and Kf were significantly increased postoperatively(all P<0.05), and posterior corneal astigmatism also increased(P=0.008). The SIA values of true net power and the anterior and posterior corneal surfaces at 3 mo postoperatively were 1.26±0.63 D(range: 0.11 to 2.80 D), 1.05±0.54 D(range: 0.23 to 2.40 D), and 0.21±0.17 D(range: 0.01 to 0.07 D), respectively. CONCLUSION: One-handed phacoemulsification with steep-axis incision can effectively decrease astigmatism of tru

关键词： steep-axis one-handed phacoemulsification true net power surgically induced astigmatism

Five-year analysis of isolated pathogens and antibiotic resistance of ocular infections from two large tertiary comprehensive hospitals in east China

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1707-1716页

作者： pan-pan li li li Jun-Fang Zhang Bai Qin li-Hua Kang Min Ji Huai-Jin Guan Suzhou Medical College of Soochow University Suzhou 215123Jiangsu ProvinceChina Department of Ophthalmology Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Clinical Laboratory Nantong City No.1 People’s Hospital and Second Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina

AIM:To analyze the spectrum of isolated pathogens and antibiotic resistance for ocular infections within 5y at two tertiary hospitals in east ***:Ocular specimen data were collected from January 2019 to October *** pathogen spectrum and positive culture rate for different infection location,such as keratitis,endophthalmitis,and periocular infections,along with antibiotic resistance were ***:We included 2727 specimens,including 827(30.33%)positive cultures.A total of 871 strains were isolated,530(60.85%)bacterial and 341(39.15%)fungal strains were ***-positive cocci(GPC)were the most common ocular *** most common bacterial isolates were Staphylococcus epidermidis(25.03%),Staphylococcus aureus(7.46%),Streptococcus pneumoniae(4.59%),Corynebacterium macginleyi(3.44%),and Pseudomonas aeruginosa(3.33%).The most common fungal genera were Fusarium spp.(12.74%),Aspergillus spp.(6.54%),and Scedosporium spp.(5.74%).Staphylococcus epidermidis strains showed more than 50%resistance to *** pneumoniae and Corynebacterium macginleyi showed more than 90%resistance to *** percentage of bacteria showing multidrug resistance(MDR)significantly decreased(χ^(2)=17.44,P=0.002).CONCLUSION:GPC are the most common ocular *** macginleyi,as the fourth common bacterium,may currently be the local microbiological feature of east *** *** the most common *** than 50%of the GPC are resistant to fluoroquinolones,penicillins,and ***,the proportion of MDR strains has been reduced over time.

关键词： ocular infections bacteria fungus antibiotic resistance multidrug resistance

Imaging presentation and postoperative recurrence of peliosis hepatis: A case report

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World Journal of Clinical Cases 2021年第19期9卷 5197-5202页

作者： Si-Xie Ren pan-pan li Hai-Peng Shi Jun-Hui Chen Zhen-Ping Deng Xi-E Zhang Department of Radiology Chengdu Second People’s HospitalChengdu 610000Sichuan ProvinceChina Pathology Center Chengdu Second People’s HospitalChengdu 610000Sichuan ProvinceChina

BACKGROUND Peliosis hepatis(PH)is a rare benign lesion of vascular origin with a pathological characteristic of multiple blood-filled cavities in the liver *** is commonly misdiagnosed due to its lack of specificity in clinical presentation and laboratory test ***,a case of a patient with PH who was misdiagnosed with hepatic echinococcosis before operation to remove the lesions was analyzed,with an emphasis on the computed tomography and magnetic resonance imaging characteristics of *** SUMMARY We outline the case of a 40-year-old Chinese female who was admitted with aggravated abdominal pain with fever for 1 *** examination at the local hospital indicated hepatic ***,discordance between imaging diagnosis,clinical history and laboratory examinations in our ***,the patient was pathologically confirmed as having PH-like changes,which recurred 1 year after operation removal of the *** Our objective is to highlight the imaging diagnostic value of PH.

关键词： Peliosis hepatis Computer tomography Magnetic resonance imaging Recurrence Misdiagnosis Case report

Engineering atomic Rb-N configurations to tune radical pathways for highly selective photocatalytic H2O2 synthesis coupled with biomass valorization

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Journal of Energy Chemistry 2025年第1期100卷 215-225页

作者： Jiaye li Shuang pan Yihuang Chen Qiong liu College of Chemistry and Materials Engineering Wenzhou University Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology (China) Institute of Analysis Guangdong Academy of Sciences (China National Analytical CenterGuangzhou)

Photocatalytic oxygen reduction for hydrogen peroxide （H2O2） synthesis presents a green and costeffective production ***,achieving highly selective H2O2synthesis remains challenging,necessitating precise control over free radical reaction pathways and minimizing undesirable oxidative ***,we report for the visible light-driven simultaneous co-photocatalytic reduction of O2to H2O2and oxidation of biomass using the atomic rubidium-nitride modified carbon nitride（CNRb）.The optimized CNRb catalyst demonstrates a record photoreduction rate of 8.01 mM h-1for H2O2generation and photooxidation rate of 3.75 mM h-1for furfuryl alcohol to furoic acid,achieving a remarkable solar-to-chemical conversion （SCC） efficiency of up to 2.27%.Experimental characterizations and DFT calculation disclosed that the introducing atomic Rb–N configurations allows for the high-selective generation of superoxide radicals while suppressing hydroxyl free radical *** is because the Rb–N serves as the new alternative site to perceive a stronger connection position for O2adsorption and reinforce the capability to extract protons,thereby triggering a high selective redox product *** study holds great potential in precisely regulating reactive radical processes at the atomic level,thereby paving the way for efficient synthesis of H2O2coupled with biomass valorization.

关键词： Atomic economy Radical pathway regulation Rubidium atom coordination Biomass valorization

Cytotoxic Acylphloroglucinol Derivatives from Callistemon salignus

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Natural Products and Bioprospecting 2017年第4期7卷 315-321页

作者： Xu-Jie Qin Tong Shu Qian Yu Huan Yan Wei Ni lin-Kun An pan-pan li Yin-E Zhi Afsar Khan Hai-Yang liu State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China Yunnan Key Laboratory of Medicinal Chemistry Kunming 650201People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China Institute of Medicinal Chemistry and Chemical Biology School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhou 510006People’s Republic of China Department of Chemistry COMSATS Institute of Information TechnologyAbbottabad 22060Pakistan

Callisalignenes G–I(1–3),three new meroterpenoids of b-triketone and monoterpene,along with two known analogues(4 and 5),were isolated from Callistemon *** structures and absolute configurations were unambiguously established by a combination of NMR and MS analysis and electronic circular dichroism(ECD)*** H(2)and I(3)have a rare sec-butyl moiety at *** 1–3 exhibited cytotoxicity against HCT116 cells with IC50 values of 8.51±1.8,9.12±0.3,and 16.33±3.3 lM,respectively.

关键词： Callistemon salignus Myrtaceae Meroterpenoids Cytotoxicity

HL-2A Tokamak Experiment Data System

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Southwestern Institute of Physics Annual Report

Southwestern Institute of Physics Annual Report 2005年第1期 77-78页

作者： CHEN liaoyuan LUO Cuiwen liYongge pan li pan Wei ZHAO li li Guohui

HL-2A tokamak experiment data system （ HL-2A EDS ） consists of an experiment network, various of dada acquiring sub-systems, a great deal of realtime data processing applications, a display system, a lot of interacting data analyzing workstations, a data storage system, a management platform, and a high performance computer. The system was built start in 2002, and has been modified greatly since then.

关键词： Data system Dada acquiring Data processing

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钢筋混凝土筒仓漏斗加固设计研究

建筑结构 2018年第6期48卷 26-30,4页

作者：潘立潘从建中国建筑科学研究院建筑结构研究所

基于滑模施工成型的钢筋混凝土筒仓分为单仓与群仓,多年来作为大型壳体仓储构筑物,已成为国内外众多水泥厂、粮库等企业的标志性建筑,其中仓底混凝土锥面漏斗主要承受截面拉力,径向与环向配筋通常由抗裂性能要求控制,一般单独支模现浇... 详细信息

基于滑模施工成型的钢筋混凝土筒仓分为单仓与群仓,多年来作为大型壳体仓储构筑物,已成为国内外众多水泥厂、粮库等企业的标志性建筑,其中仓底混凝土锥面漏斗主要承受截面拉力,径向与环向配筋通常由抗裂性能要求控制,一般单独支模现浇成型。通过某工程混凝土群仓漏斗裂损与安全度缺陷的加固设计,对比研究了所提出的两个可行加固方案,分别为：顶面与底面粘贴碳纤维片材和顶面新增配筋混凝土覆壳。详述了选定方案的加固验算条件、过程与结果,并给出了相应设计说明与技术建议,可供同类筒仓结构设计和施工参考。

关键词：钢筋混凝土筒仓混凝土漏斗锥面壳体最大裂缝宽度碳纤维片材(CFS) 混凝土覆壳隔离层

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Defect Engineering:Can it Mitigate Strong Coulomb Effect of Mg^(2+)in Cathode Materials for Rechargeable Magnesium Batteries?

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Nano-Micro Letters 2025年第1期17卷 135-159页

作者： Zhengqing Fan Ruimin li Xin Zhang Wanyu Zhao Zhenghui pan Xiaowei Yang School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Chemistry and Chemical Engineering Taiyuan University of TechnologyTaiyuan 030024People’s Republic of China School of Materials Science and Engineering Tongji UniversityShanghai 201804People’s Republic of China

Rechargeable magnesium batteries(RMBs)have been considered a promising“post lithium-ion battery”system to meet the rapidly increasing demand of the emerging electric vehicle and grid energy storage ***,the sluggish diffusion kinetics of bivalent Mg^(2+)in the host material,related to the strong Coulomb effect between Mg^(2+)and host anion lattices,hinders their further development toward practical *** engineering,regarded as an effective strategy to break through the slow migration puzzle,has been validated in various cathode materials for *** this review,we first thoroughly understand the intrinsic mechanism of Mg^(2+)diffusion in cathode materials,from which the key factors affecting ion diffusion are further ***,the positive effects of purposely introduced defects,including vacancy and doping,and the corresponding strategies for introducing various defects are *** applications of defect engineering in cathode materials for RMBs with advanced electrochemical properties are also ***,the existing challenges and future perspectives of defect engineering in cathode materials for the overall high-performance RMBs are described.

关键词： Rechargeable magnesium battery Sluggish diffusion kinetic Defect engineering Cathode materials Ion migration

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