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Failure rate,return-to-sports and magnetic resonance imaging after meniscal repair:119 patients with 7 years mean follow up

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世界骨科杂志:英文版 2023年第8期14卷 612-620页

作者： Juan pablo Zicaro Nicolas Garrido Ignacio garcia-Mansilla Carlos Yacuzzi Matias Costa-Paz Department of Knee Hospital Italiano de Buenos AiresBuenos Aires 1109Argentina

BACKGROUND One of the most important factors to consider in relation to meniscal repair is the high failure rate reported in the existing *** To evaluate failure rates,return to sports(RTS)rate,clinical outcomes and magnetic resonance image(MRI)evaluation after meniscus suture repair for longitudinal tears at a minimum *** We conducted a retrospective review of meniscal repairs between January 2004 and December *** patients treated for longitudinal tears associated or not with an anterior cruciate ligament reconstruction(ACL-R)were *** ramp lesions,radial and root tears,associated with multiligament injuries,tibial fracture and meniscal allograft transplants were *** details and failure rate,defined as symptomatic patients who underwent a revision surgery,were *** isolated bucket handle tears(BHTs)were usually associated with higher failure rates,we compared BHTs and not BHTs associated or not with an *** 2014,the inside-out technique using cannulas and suture needles with 2-0 Tycron began to *** addition,the number of stitches per repair was *** view of differences in surgical technique,we compared two different cohorts:before and after *** recorded the RTS according to the level achieved and the time to *** and IKDC scores were *** were studied with x-rays and MRI as standard postoperative *** One hundred and nineteen patients were included with a mean follow up of 7 years(SD:4.08).Overall failure rate was 20.3%at a mean 20.1 *** statistically significant differences were found when comparing failure for medial and lateral meniscal repair(22.7%and 15.3%,P=0.36),BHTs and not BHTs(26%and 17.6%,P=0.27),isolated or associated with an ACL-R(22.9%and 18%,P=0.47),or when comparing only BHTs associated with an ACL-R(23%and 27.7%,P=0.9)or *** comparing cohorts before and after 2014,we found a significant decrease in the overall f

关键词： Meniscus repair Bucket handle tears Meniscal suture Failure rate Longitudinal meniscus tears

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Has platelet-rich plasma any role in partial tears of the anterior cruciate ligament?Prospective comparative study

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World Journal of Orthopedics 2021年第6期12卷 423-432页

作者： Juan pablo Zicaro Ignacio garcia-Mansilla Andres Zuain Carlos Yacuzzi Matias Costa-Paz Knee Division Hospital Italiano de Buenos AiresBuenos Aires 1181Argentina

BACKGROUND Partial tears of the anterior cruciate ligament(ACL)are frequent,and there is still considerable controversy surrounding their diagnosis,natural history and *** To examine patient-reported outcomes,physical examination and magnetic resonance imaging(MRI)findings of partial ACL tears treated with an intraarticular injection of platelet-rich plasma(PRP)compared to a control *** From January 2015 to November 2017,consecutive patients from a single institution with partial ACL tears treated nonoperatively were prospectively *** tears were defined as a positive Lachman test with a clear endpoint,a negative pivot-shift and less than 3 mm of side-to-side difference using the KT1000 *** in group 1 were treated with one intraarticular injection of PRP and specific physical therapy *** group consisted of patients treated only with physical *** analyzed data included physical examination,Tegner activity level and Lysholm and International Knee Documentation Committee *** MRI findings and at 6 mo follow-up were *** was defined as those patients with clinical instability at follow-up that required a subsequent ACL *** A total of 40 patients where included,21 treated with PRP injection with a mean follow-up of 25 mo[standard deviation(SD):3.6]and 19 in the control group with a mean follow-up of 25 mo(SD:5.68).Overall failure rate was 32.0%(n=13).No significant differences were observed between groups regarding subjective outcomes,return to sport and failure *** findings revealed an improvement in the ACL signal in half of the patients of both ***,we did not find a significant relationship between MRI findings and clinical *** Overall,95.0%of patients returned to sports at a mean follow-up of 25 *** time to return to sports was 4 *** of these patients,almost 30.0%in each group had a new episode of instability

关键词： Anterior cruciate ligament Partial tears Platelet-rich plasma Non-operative treatment

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Revision anterior cruciate ligament reconstruction:Return to sports at a minimum 5-year follow-up

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World Journal of Orthopedics 2022年第9期13卷 812-824页

作者： Ezequiel Ortiz Juan pablo Zicaro Ignacio garcia Mansilla Carlos Yacuzzi Matias Costa-Paz Knee Division Hospital Italiano de Buenos AiresCiudad Autónoma 1181Buenos AiresArgentina

BACKGROUND Between 43%and 75%of patients who undergo primary anterior cruciate ligament(ACL)surgery return to sport ***,after a revision ACL reconstruction(ACLR)the rate of return to sports is variable.A few publications have reported returns to sports incidence between 56%to 100%after revision *** To determine return to sports and functional outcomes after a single-stage revision ACLR with a 5-year minimum follow-up at a single *** All patients operated between 2010 and 2016 with a minimum 5 years of followup were *** of sport,intensity,frequency,expectation,time to return to sport and failure rate were ***,Tegner and International Knee Documentation Committee forms were evaluated prior to the first ACLR surgery,at 6 mo after primary surgery and after revision ACLR at 5 years minimum of *** stability was tested with the knee arthrometer test(KT-1000 knee arthrometer,Medmetric Corp).RESULTS A total of 41 patients who underwent revision ACLR during that period of time were contacted and available for *** patient age at time of revision was 29 years old[interquartile range(IQR):24.0-36.0],and 39(95.0%)were *** median time from revision procedure to follow-up was 70 mo(IQR:58.0-81.0).Regarding return to sports,16(39.0%)were at the same level compared to preinjury period,and 25 patients(61.0%)returned at a lower ***-three percent categorized the sport as very important and 37.0%as *** patient(2.4%)failed with a recurrent ACL *** preoperative Lysholm and(SD)16]and 50(SD 11),*** follow-up,mean Lysholm and subjective International Knee Documentation Committee scores were 89(SD 8)and 82(SD 9)(P=0.0001).Mean Tegner score prior to primary ACLR was 6.7(SD 1.3),5.1(1.5 SD)prior to revision ACLR and 5.6(1.6 SD)at follow-up(P=0.0002).Overall,knee arthrometer test measurement showed an average of 6 mm(IQR:4.0-6.0)side-to-side difference of displacement pri

关键词： Return to sport Revision anterior cruciate ligament Arthroscopy Knee Functional outcome

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Fertirrigation with Low-Pressure Multi-Gate Irrigation Systems in Sugarcane Agroecosystems:A Review

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Pedosphere 2019年第1期29卷 1-11页

作者： Arturo garcia-SALDANA Cesareo LANDEROS-SANCHEZ Maria del Refugio CASTANEDA-CHAVEZ Juan pablo MARTINEZ-DAVILA Arturo PEREZ-VAZQUEZ Eugenio CARRILLO-AVILA Postgraduate College Campus Veracruz Tepetates C.P.91674(Mexico) Technological Institute of Boca del Rio(ITBOCA) Boca del Rio C.P.94290(Mexico) Postgraduate College Campus Campeche Campeche C.P.24450(Mexico)

There are very few studies on the application of fertilizers through irrigation water(fertirrigation) using a multi-gate irrigation system in sugarcane AES. Through fertirrigation, the application of fertilizers can be simplified, and their distribution uniformity in sugarcane fields improved. This paper provides an overview of the state of the art regarding fertirrigation with multi-gate irrigation in sugarcane agroecosystems(AES). In order to systematize, organize, and discuss the scientific data on fertirrigation with low-pressure multi-gate irrigation systems in sugarcane AES, bibliographic material from the following full-text scientific journal databases was screened: the Elsevier Science Direct Freedom Collection, Springer Link, and the International Society for Horticultural Science. Next,a matrix of keywords was used to analyze the interrelationships among the available literature, current issues, and the recent *** conclude that development of fertirrigation technologies with low-pressure multi-gate irrigation is much needed.

关键词： climate change crop water requirement fertilizer application fertilizer distribution uniformity sugarcane industry water use efficiency

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Human-Exoskeleton Joint Coordination Assessment:A Case Study on the Shoulder and Elbow Joints

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Journal of Bionic Engineering 2022年第6期19卷 1712-1721页

作者： pablo Delgado Clarissa Rincon Yimesker Yihun Mechanical Engineering Wichita State University1845 FairmountWichitaKS67260USA Biomedical Engineering Wichita State University1845 FairmountWichitaKS67260USA

This study is aimed at developing a methodology to assess and quantify the human limb motions and interactions with the exoskeleton in relation to *** different basic and common upper arm joint movements and their interaction with a joint-based exoskeleton are considered:shoulder vertical and horizontal abduction-adduction,and elbow *** exoskeleton and the human model are aligned to the respective joints inside a Musculoskeletal Modeling *** the range of motion,the linear and angular displacement errors were analyzed,and the effect of those errors on the length of the associated tendons was *** have shown a noticeable variation of the muscle-tendon lengths up to 65.7 mm and a change in the pattern on different muscle groups of the ***,about 4 mm muscle-tendon length changes observed particularly at the elbow anconeus *** changes of length could cause unwanted stresses at the joints,specially for people with disabilities due to stroke that might not have the flexibility to accommodate those extra pose variations imposed by the exoskeleton.

关键词： Exoskeleton Upper limb Rehabilitation Misalignment OpenSim Computational modeling Bioinspiration

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The VILMA intelligent vehicle:an architectural design for cooperative control between driver and automated system

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Journal of Modern Transportation 2018年第3期26卷 220-229页

作者： Olmer garcia Giovani Bernardes Vitor Janito Vaqueiro Ferreira pablo Siqueira Meirelles Arthurde Miranda Neto Universidad de Bogota Jorge Tadeo Lozano BogotaColombia Robotics Intelligent and Complex Systems(RobSIC)LabUniversidade Federal de Itajuba′(UNIFEI)ItabiraMGBrazil Autonomous Mobility Lab at the Universidade Estadual de Campinas(UNICAMP)CampinasSP 13083-860Brazil Terrestrial Mobility Lab at the Universidade Federal de Lavras (UFLA)LavrasMG 37200-000Brazil

Intelligent autonomous vehicles have received a great degree of attention in recent years. Although the technology required for these vehicles is relatively advanced, the challenge is firstly to ensure that drivers can understand the capabilities and limitations of such systems and secondly to design a system that can handle the interaction between the driver and the automated intelligent system. In this study, we describe an approach using different strategies for an autonomous system and a driver to drive a vehicle cooperatively. The proposed strategies are referred to as cooperative planning and control and determine when and how the path projected by the autonomous system can be changed safely by the driver to a path that he wishes to follow. The first phase of the project is described, covering the design and implementation of an autonomous test vehicle. Experiments are carried out with a driver to test the cooperative planning and control concepts proposed here.

关键词： Autonomous vehicles Embedded systems Cooperative systems Visual servoing

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Folate Metabolism Interferes with Plant Immunity through 1C Methionine Synthase-Directed Genome-wide DNA Methylation Enhancement

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Molecular Plant 2019年第9期12卷 1227-1242页

作者： Beatriz Gonzalez pablo Vera Instituto de Biologia Molecular y Celular de Plantas Universidad Politecnica de Valencia-C.S.I.CCiudad Politecnica de la InnovacionEdificio 8EIngeniero Fausto Elios/n.46022 ValenciaSpain

Plants rely on primary metabolism for flexible adaptation to environmental ***,through a combination of chemical genetics and forward genetic studies in Arabidopsis plants,we identified that the essential folate metabolic pathway exerts a salicylic acid-independent negative control on plant *** of the folate pathway promotes enhanced resistance to Pseudom onas syringae DC3000 via activation of a primed immune state in plants,whereas its implementation results in enhanced *** proteomics analysis using immune-defective mutants identified a methionine synthase(METS1),in charge of the synthesis of Met through the folate-dependent 1C metabolism,acting as a nexus between the folate pathway and plant *** of METS1 represses plant immunity and is accompanied by genome-wide global increase in DNA methylation,revealing that imposing a methylation pressure at the genomic level compromises plant *** together,these results indicate that the folate pathway represents a new layer of complexity in the regulation of plant defense responses.

关键词： folate pathway plant immunity methionine DNA methylation

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THE BLOCH SPACE ON THE UNIT BALL OF A HILBERT SPACE: MAXIMALITY AND MULTIPLIERS

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Acta Mathematica Scientia 2021年第3期41卷 899-906页

作者： pablo GALINDO Mikael LINDSTRÖM Departamento de Análisis Matemático Universidad de Valencia.C/Dr.Moliner 50.46.100BurjasotValenciaSpain Department of Mathematics Abo Akademi University.FI-20500ÅboFinland

We prove that, as in the finite dimensional case, the space of Bloch functions on the unit ball of a Hilbert space contains, under very mild conditions, any semi-Banach space of analytic functions invariant under automorphisms. The multipliers for such Bloch space are characterized and some of their spectral properties are described.

关键词： Analytic functions on Hilbert space invariance under automorphisms multiplier

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Weak Gravity Conjecture and extremal black holes

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Science China(Physics,Mechanics & Astronomy) 2019年第11期62卷 69-86页

作者： William Cottrell Gary Shiu pablo Soler Department of Physics University of WisconsinMadison WI53706USA Institut fur Theoretische Physik Universitat HeidelbergPhilosophenweg19Heidelberg D-69120Germany

Motivated by the desire to improve our understanding of the Weak Gravity Conjecture, we compute the one-loop correction of charged particles to the geometry and entropy of extremal black holes in 4D. We use the entropy function formalism to extend previous analysis that dealt with neutral particles, and obtain the corrections to the horizon entropy for different regimes of black hole masses. These corrections are small in general. They are furthermore reduced when supersymmetry is present, and disappear in N = 4 supergravity. We provide some speculative arguments that in a theory with only sub-extremal particles, classical Reissner-Nordstrom black holes actually possess an infinite microcanonical entropy, though only a finite amount is visible to an external observer, as shown by the horizon entropy computation.

关键词： black holes string theory entropy

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Reconstruction of lateral root formation through single-cell RNA sequencing reveals order of tissue in itiation

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Molecular Plant 2021年第8期14卷 1362-1378页

作者： Laura Serrano-Ron pablo Perez-garcia Alvaro Sanchez-Corrionero Inmaculada Gude Javier Cabrera Pui-Leng Ip Kenneth D.Birnbaum Miguel A.Moreno-Risueno Centro de Biotecnologia y Genomica de Plantas Universidad Politecnica de Madrid(UPM)-lnstituto Naci on al de Investigacion y Tec no logia Agraria y Alimentaria(INIA)Pozuelo de Alarcon28223 MadridSpain Departamento de Biotecnologia-Biologia Vegetal Escuela Tecnica Superior de Ingenieria AgronomicaAlimentaria y de BiosistemasUniversidad Politecnica de Madrid(UPM)28040 MadridSpain Center for Genomics and Systems Biology Department of BiologyNew York UniversityNew YorkNYUSA

Postembryonic organogenesis is critical for plant ***,lateral roots(LRs)form the bulk of mature root systems,yet the ontogeny of the LR primordium(LRP)is not *** this study,we performed the single-cell RNA sequencing through the first four stages of LR formation in *** analysis led to a model in which a single group of precursor cells,with a cell identity different from their pericycle origins,rapidly reprograms and splits into a mixed ground tissue/stem cell niche fate and a vascular precursor *** ground tissue and stem cell niche fates soon separate and a subset of more specialized vascular cells form sucrose transporting phloem cells that appear to connect to the primary *** did not detect cells resembling epidermis or root cap,suggesting that outer tissues may form later,preceding LR *** this stage,some remaining initial precursor cells form the primordium flanks,while the rest create a reservoir of pluripotent cells that are able to replace the LR if *** ablation of the central and lateral LRP regions showed that remaining cells restart the sequence of tissue initiation to form a ***,our study reveals an ontological hierarchy for LR formation with an early and sequential split of main root tissues and stem cells.

关键词： organogenesis patterning stem cells single-cell RNA-seq cell fate regeneration

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