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Navigating medial patellotibial ligament reconstruction:Clinical perspectives and surgical strategies

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World Journal of Clinical Cases 2025年第1期13卷 6-10页

作者： Juan pablo Zicaro Ignacio garcia-Mansilla Division of Knee Hospital Italiano de Buenos AiresBuenos Aires 1109Argentina

The surgical approach for patellar instability usually refers to reconstruction of the medial patellofemoral ligament associated with an osteotomy of the tibial tuberosity or a trochleoplasty when *** medial patellotibial ligament and the medial patellomeniscal ligament are secondary stabilizers of the *** this,both the medial patellotibial and patellofemoral ligaments aid in patellar rotation and tilt when the knee is flexed beyond 45°.The medial patellotibial ligament plays a particularly important role in the final stages of stretching in extension and between 40 degrees to 90 degrees of *** clinical relevance and surgical indications for medial patellotibial ligament reconstruction associated with medial patellofemoral ligament reconstruction are still *** editorial explores the surgical indications and clinical results for medial patellotibial ligament reconstruction to improve readers’understanding of this technique,especially because reported clinical outcomes have remained sparse.

关键词： Medial patellotibial ligament Patellar instability Reconstruction Surgical

A simple and fast method to calculate the coil currents and the external poloidal flux and magnetic field for fixed boundary equilibria

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Plasma Science and Technology 2024年第11期26卷 65-70页

作者： Ricardo FARENGO pablo L garcÍA-MARTÍNEZ Hugo E FERRARI Centro Atómico Bariloche Comisión Nacional de Energía AtómicaBariloche 8400Argentina Instituto Balseiro Universidad Nacional de CuyoBariloche 8400Argentina CONICET CCT-Patagonia Norte Bariloche 8400Argentina

A simple and fast method to calculate the coil currents and the external poloidal flux and magnetic field consistent with a given internal magnetohydrodynamic(MHD) equilibrium and coil geometry is presented. The constrained optimization technique employed allows to fix the exact position of the X-points. The external poloidal flux and field are calculated using Green's functions expressed in terms of elliptic integrals that are calculated using a fast and accurate *** calculation can be limited to the region between the plasma and the device wall. An example for a double null configuration is presented.

关键词： MHD equilibrium Green's functions tokamak

RESIDENTIAL SOLAR ENERGY POTENTIAL FOR PUBLIC DISSEMINATION:A CASE STUDY IN CONCEPCION,CHILE

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Journal of Green Building 2016年第1期11卷 118-133页

作者： Rodrigo garcía Alvarado Lorena Troncoso pablo Campos University of Bio-Bío Department of Design and Theory of ArchitectureConcepciónChile University of Concepción Department of Mechanical EngineeringConcepciónChile

This paper presents a method for estimating the solar capture capacity of dwell-ings using the central urban area of Concepción,Chile,as a case study in order to promote self-generation of energy by *** method takes into account the growing domestic energy demand and the possibility of meeting this demand through integrated solar energy collection into buildings using different *** methodology considers a study of the potential incoming solar radiation on buildings according to their geographical location and the surrounding *** capacity for solar capture is then estimated for different dwelling types accord-ing to their ***,the energy contribution provided by differ-ent technologies(solar thermal,photovoltaic and hybrid)is identified in relation to the main average energy demands for electricity,water and space ***,systems for each dwelling are recommended in an urban map available *** development is based on climate information,cartography,aerial photo-graphs,surveys,housing models,technical standards,standardised calculations and dynamic simulations,implemented according to building layouts from an online Geographic Information System(GIS).The housing types are categorised in an urban map that relates household demands and the contribution of different solar energy *** to the estimates calculated,the residential units in the study offer sufficient solar capacity to supply between 40 and 60%of their energy consumption,especially in detached houses using roof-mounted hybrid systems.

关键词： solar energy urban area housing solar map Concepción Chile

Elastic Smart Contracts in Blockchains

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IEEE/CAA Journal of Automatica Sinica 2021年第12期8卷 1901-1912页

作者： Schahram Dustdar pablo Fernández JoséMaría garcía Antonio Ruiz-Cortés Distributed Systems Group Vienna University of TechnologyWien 1040Austria Smart Computer Systems Research and Engineering Lab Research Institute of Computer EngineeringUniversity of SevillaSevilla 41012Spain

In this paper,we deal with questions related to blockchains in complex Internet of Things(IoT)-based *** ecosystems are typically composed of IoT devices,edge devices,cloud computing software services,as well as people,who are decision makers in scenarios such as smart *** decisions related to analytics can be based on data coming from IoT sensors,software services,and ***,they are typically based on different levels of abstraction and *** poses a number of challenges when multiple blockchains are used together with smart *** work proposes to apply our concept of elasticity to smart contracts and thereby enabling analytics in and between multiple blockchains in the context of *** propose a reference architecture for Elastic Smart Contracts and evaluate the approach in a smart city scenario,discussing the benefits in terms of performance and self-adaptability of our solution.

关键词： Blockchain elasticity Internet of Things(IoT) smart cities smart contracts virtual chains

Energy management of micro renewable energy source and electric vehicles at home level

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Journal of Modern Power Systems and Clean Energy 2017年第6期5卷 979-990页

作者： Ibán JUNQUERA MARTíNEZ Javier garcíA-VILLALOBOS Inmaculada ZAMORA pablo EGUíA Department of Electrical Engineering University of the Basque CountryLeioaSpain

As renewable energy source(RES)tend to be integrated more and more at home and electric vehicles(EVs)take a greater share in the personal automobile market,users see a chance to charge their EVs by *** this context,this paper presents a review about opportunities and challenges needed to be overcome by the EV users to implement a vehicle to home system in their homes,as well as the integration of *** practical scenarios are presented,with different demand profiles,by integrating renewable energy that could be used to charge the EV.

关键词： Plug-in electric vehicles(PEV) Vehicle to home(V2H) Micro renewable energy source(micro-RES) Challenges

Central nervous system stimulation therapies in phantom limb pain:a systematic review of clinical trials

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Neural Regeneration Research 2022年第1期17卷 59-64页

作者： M.Ángeles garcía-Pallero Diana Cardona Lola Rueda-Ruzafa Miguel Rodriguez-Arrastia pablo Roman Hospital Universitario Central de Asturias AsturiasSpain Department of Nursing Science Physiotherapy and MedicineUniversity of AlmeríaAlmeríaSpain Department of Functional Biology and Health Sciences Faculty of Biology-CINBIOUniversity of VigoVigoPontevedraSpain Faculty of Health Sciences Pre-Department of NursingJaume I UniversityCastello de la PlanaSpain Research Group CYS Faculty of Health SciencesJaume I UniversityCastello de la PlanaSpain

Phantom limb pain is a chronic pain syndrome that is difficult to cope *** neurostimulation treatment is indicated for refractory neuropathic pain,there is scant evidence from randomized controlled trials to recommend it as the treatment ***,a systematic review was performed to analyze the efficacy of central nervous system stimulation therapies as a strategy for pain management in patients with phantom limb pain.A literature search for studies conducted between 1970 and September 2020 was carried out using the MEDLINE and Embase *** of The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline were *** were a total of 10 full-text articles retrieved and included in this *** brain stimulation,repetitive transcranial magnetic stimulation,transcranial direct current stimulation,and motor cortex stimulation were the treatment strategies used in the selected clinical *** transcranial magnetic stimulation and transcranial direct current stimulation were effective therapies to reduce pain perception,as well as to relieve anxiety and depression symptoms in phantom limb pain ***,invasive approaches were considered the last treatment option as evidence in deep brain stimulation and motor cortex stimulation suggests that the value of phantom limb pain treatment remains ***,the findings on use of these treatment strategies in other forms of neuropathic pain suggest that these invasive approaches could be a potential option for phantom limb pain patients.

关键词： central nervous system stimulation neuromodulation neuropathic pain phantom limb pain systematic review

Effect of the filling season on aquatic plants in Mediterranean temporary ponds

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Journal of Plant Ecology 2018年第3期11卷 502-510页

作者： Rocío Fernández-Zamudio pablo garcía-Murillo Carmen Díaz-Paniagua Doñana Biological Station-CSIC Avda.Américo Vespucio s/n41092 SevilleSpain Department of Plant Biology and Ecology Faculty of PharmacyUniversity of SevilleSevilleSpain

Aims Pond environmental conditions may differ among years with regards to the season in which ponds begin to *** experimen-tally evaluated how seedling emergence,plant growth and phe-nology differed among years in which filling occurred in winter,autumn or *** We collected sediments from a natural temporary pond and located them in *** were placed in a climatic chamber that simulated annual variation in field environmental temperatures and light *** were assigned to one of three treat-ments,which differed in the date on which they were filled with water(autumn,winter and spring).We counted the number of seed-lings of different species emerged and recorded data about the pres-ence of flowers,seeds or spores every *** experiment was finished in June,when we harvested the plants and estimated their *** Findings In most species,seedling emergences were primarily related to time after filling,and thus synchronized their life cycles with the unpre-dictably timed wet phase of the *** filling resulted in the highest numbers of seeds/***,winter filling pro-moted plant growth the *** the spring filling treatment,more terrestrial plant seedlings emerged and fewer seeds/spores were *** ponds are flooded earlier,plants may produce a higher number of ***,in years when inundation is delayed to spring and hydroperiods are short,seedling emergence deplete the seed bank and there is little to no seed production,while terrestrial monocots are able to colonize pond basin.

关键词： Aquatic plants temporary ponds seed bank seedlings germination

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan pablo de Rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy Department of Surgery Morehouse School of MedicineAtlantaGAUSA Department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Department of Neurological Surgery and the Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric Critical Care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Pediatrics Emory UniversityAtlantaGAUSA Department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Department of Chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury

Uncertainties in the Mercury Mass Balance in a Coal-Based IGCC Power Plant (Puertollano, Spain)

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Energy Engineering 2021年第4期118卷 1223-1235页

作者： José María Esbrí Alba Martinez-Coronado Sofía Rivera Jurado Eva garcía-Noguero pablo Higueras Instituto de Geología Aplicada(UCLM) Pl.Manuel Meca1Ciudad Real13400Spain

Mercury(Hg)is a global pollutant that is subject to strict regulations to reduce anthropogenic *** production of energy represents an important activity that leads to Hg emissions into the *** all the systems used,IGCC plants are the most promising for reducing Hg emissions,since it is possible to remove Hg from syngas prior to *** aim of the present work was to evaluate the presence of Hg in the main streams of an experimental IGCC plant(ELCOGAS,Puertollano)in order to quantify Hg emissions and investigate the possibility of reducing *** main streams of the system were sampled for three consecutive days and both the solids,i.e.,raw material(coal and petroleum coke),fine and coarse slags,fly ash,sulphur,and the liquids,i.e.,slag system,Venturi scrubber and saturator,were *** results show that an average of 12.9%of the Hg that enters the IGCC power plant is eliminated with solid waste and only 0.08%with liquid *** is still an average of 87.12%of Hg that is not accounted for in the mass balance and that could remain in the system and/or be eliminated in the streams that were not *** it is impossible to offer an explanation for the final fate of the Hg lost in the system based on the obtained results,the data suggest that sulphur byproducts could be primarily responsible for the elimination of Hg from the syngas,and that a major proportion of Hg should be emitted via the chimney after the syngas combustion process.

关键词： Mercury IGCC power plant mass-balance hypercinnabar