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Federated Network Intelligence Orchestration for Scalable and Automated FL-Based Anomaly Detection in B5G Networks

Computers, Materials & Continua 2024年第7期80卷 163-193页

作者： pablo Fernández Saura José M.Bernabé Murcia Emilio García de la Calera Molina Alejandro Molina Zarca Jorge Bernal Bernabé Antonio F.Skarmeta Gómez Department of Information and Communications Engineering University of MurciaMurcia30100Spain University Center of Defense Spanish Air Force AcademySan Javier30720Spain

The management of network intelligence in Beyond 5G(B5G)networks encompasses the complex challenges of scalability,dynamicity,interoperability,privacy,and *** are essential steps towards achieving the realization of truly ubiquitous Artificial Intelligence(AI)-based analytics,empowering seamless integration across the entire Continuum(Edge,Fog,Core,Cloud).This paper introduces a Federated Network Intelligence Orchestration approach aimed at scalable and automated Federated Learning(FL)-based anomaly detection in *** leveraging a horizontal Federated learning approach based on the FedAvg aggregation algorithm,which employs a deep autoencoder model trained on non-anomalous traffic samples to recognize normal behavior,the systemorchestrates network intelligence to detect and prevent *** into a B5G Zero-touch Service Management(ZSM)aligned Security Framework,the proposal utilizes multi-domain and multi-tenant orchestration to automate and scale the deployment of FL-agents and AI-based anomaly detectors,enhancing reaction capabilities against *** proposed FL architecture can be dynamically deployed across the B5G Continuum,utilizing a hierarchy of Network Intelligence orchestrators for real-time anomaly and security threat *** includes FL enforcement operations for interoperability and extensibility,enabling dynamic deployment,configuration,and reconfiguration on *** validation of the proposed solution was conducted through dynamic orchestration,FL,and real-time anomaly detection processes using a practical test *** of key performance metrics,leveraging the 5G-NIDD dataset,demonstrates the system’s capability for automatic and near real-time handling of anomalies and attacks,including real-time network monitoring and countermeasure implementation for mitigation.

关键词： Federated learning 6G orchestration anomaly detection security policy

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Vinyl sulfonyl chemistry-driven unidirectional transport of a macrocycle through a[2]rotaxane

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Organic Chemistry Frontiers 2022年第3期9卷 633-642页

作者： Arthur H.G.David pablo García-Cerezo Araceli G.Campaña Francisco Santoyo-gonzález Victor Blanco Departamento de Química Orgánica Facultad de CienciasUnidad de Excelencia de Química Aplicada a Biomedicina y Medioambiente(UEQ)Universidad de Granada(UGR)Avda.Fuente Nueva S/N18071 GranadaSpain

By applying a combination of the coupling-and-decoupling(CAD)chemistry of the vinyl sulfonate group with the click thia-Michael addition to the vinyl sulfone group(MAVS)we performed the irreversible unidirectional transportation of the ring through the linear component in a[2]rotaxane by a chemically and pHdriven flashing energy ratchet mechanism.

关键词： mechanism unidirectional chemistry

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Physical activity and amyloid beta in middle-aged and older adults:A systematic review and meta-analysis

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Journal of Sport and Health Science 2024年第2期13卷 133-144页

作者： María Rodriguez-Ayllon Patricio Solis-Urra Cristina Arroyo-ávila Miriam álvarez-Ortega pablo Molina-García Cristina Molina-Hidalgo Manuel Gómez-Río Belinda Brown Kirk I.Erickson Irene Esteban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and Social Sciences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Physical Medicine and Rehabilitation Service Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Psychology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia School of Medical and Health Sciences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health Research Institute Neuroscience Institute OrlandoOrlandoFL 32803USA Physiopathology of Obesity and Nutrition Research Center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels *** aimed to explore the relationship between physical activity and Aβin middle-aged and older ***:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,*** were eligible if they included physical activity and Aβdata in adults aged 45 years or ***-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβ***:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and *** physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older ***,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included *** observational studies,higher levels of physical activity were positively associated with Aβonly in ***,further research is needed t

关键词： Aging Cognitive impairment Dementia Exercise PET

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Phylogenetic alpha and beta diversity in tropical tree assemblages along regionalscale environmental gradients in northwest South America

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Journal of Plant Ecology 2014年第2期7卷 145-153页

作者： Sebastián gonzález-Caro María Natalia Umaña Esteban Álvarez pablo R.Stevenson Nathan G.Swenson Ecosystem Services&Climate Change Lab Botanical Garden of MedellínMedellínAntioquia 050001Colombia Department of Plant Biology Michigan State UniversityEast LansingMI 48824USA Department of Ecology Universidad de AlcaláAlcaláMadrid 28801Spain Department of Biological Sciences Universidad de Los AndesBogotá7495Colombia

Aims Environmental gradients are drivers of species diversity;however,we know relatively little about the evolutionary processes underlying these relationships.A potentially powerful approach to studying diversity gradients is to quantify the phylogenetic structure within and between assemblages arrayed along broad spatial and environmental ***,we evaluate the phylogenetic structure of plant assemblages along an environmental gradient with the expectation that the habitat specialization of entire lineages is an important evolutionary pattern influencing the structure of tree communities along environmental *** We evaluated the effect of several environmental variables on the phylogenetic structure of plant assemblages in 145 plots distributed in northwestern South America that cover a broad environmental *** phylogenetic alpha diversity was quantified for each plot and the phylogenetic beta diversity between each pair of plots was also *** the alpha and beta diversity measures were then related to spatial and environmental gradients in the study *** Findings We found that gradients in temperature and potential evapotranspiration have a strong relationship with the phylogenetic alpha diversity in our study system,with phylogenetic overdispersion in low temperatures and phylogenetic clustering at higher ***,the phylogenetic beta diversity between two plots increases with an increasing difference in temperature,whereas annual precipitation was not a significant predictor of community phylogenetic *** also found that the phylogenetic structure of the plots in our study system was related to the degree of seasonal flooding and seasonality in *** particular,more stressful environments such as dry forests and flooded forests showed phylogenetic ***,in contrast with previous studies,we find that phylogenetic beta diversity was not strongly related to the spatial d

关键词： phylogenetic conservatism habitat filtering immigration environmental gradient

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Quantification of the Vertical Load Applied to the Pavement during Cornering Maneuver of a Battery Electric Commercial Vehicle

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Journal of Traffic and Transportation Engineering 2024年第5期12卷 207-213页

作者： pablo Kubo Ney Siqueira Gilberto Grossl Luis Welin Mairon Dobicz Marcio Andrade Department of Complete Vehicle Volvo Group North AmericaGreensboro 27409USA Department of Complete Vehicle Volvo Trucks BrazilCuritiba 81260-900Brazil

The wheel loads of heavy trucks are the major source of pavement damage,given the repeated loadings imposed by them due to transient events and surface *** related studies focus on steady-state context regarding simplified vehicle’s parameters and ideal pavement conditions,this paper aims to analyze the vertical load applied to the pavement by considering cornering maneuver as a transient event,on a battery electric vehicle *** this concern,measurements were performed on a rigid truck,with two steering front axles,in a closed course proving *** relationship has been presented between vehicle’s speed,lateral acceleration and transferred vertical load for a given curve radius of 85.6 m and 3.7°of transversal *** measurements results indicated that for every 10 km/h increasing on the vehicle’s speed,additional 110 kgf will be transferred to the pavement on the outer side of the cornering *** value itself could not be considered high,but it will be also added to the static load,or overload in some truck applications.

关键词： Load transfer durability vehicle dynamics

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Predefined-Time Backstepping Stabilization of Autonomous Nonlinear Systems

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IEEE/CAA Journal of Automatica Sinica 2022年第11期9卷 2020-2022页

作者： Alison Garza-alonso Michael Basin pablo Cesar Rodriguez-Ramirez the School of Physical and Mathematical Sciences Autonomous University of Nuevo LeonSan Nicolas de los GarzaNuevo Leon 66455Mexico Ningbo Institute of Intelligent Equipment Technology Zhejiang 315032China

Dear Editor,In this letter,the backstepping technique is applied to solve the predefined-time stabilization problem for autonomous nonlinear systems,where nonlinear terms are unknown but satisfy a linear growth condition.A linear time-varying control law is designed to drive all states of an autonomous nonlinear system to the origin for an a priori preassigned time.

关键词： nonlinear autonomous satisfy

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Deposition of carbon nanotubes onto glass fibers using ultrasound standing waves

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Frontiers of Materials Science 2021年第3期15卷 471-475页

作者： Julio Alejandro RODRÍGUEZ-gonzÁlez Carlos RUBIO-gonzÁlez Alfonso PÉREZ-SÁNCHEZ Centro de Ingeniería y Desarrollo Industrial Departamento de EnergíaAv.Pie de la Cuesta#702Col.Desarrollo San PabloC.P.76125QuerétaroQroMexico

Carbon nanotubes(CNTs)are special types of carbon nanostructures with exceptional physical and mechanical properties such as high elastic modulus,high electrical and thermal conductivities,as well as high surface area and large aspect ratios[1].Given their tubular structure and size,CNTs are conceptualized as one-dimensional nanostructures with a crystalline structure of carbon sp2 hybridization formed by carbon–carbon covalent bonds[1].

关键词： carbon fibers exceptional

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Insects as alternative feed for ruminants:comparison of protein evaluation methods

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Journal of Animal Science and Biotechnology 2022年第4期13卷 1143-1150页

作者： pablo G.Toral gonzalo Hervás Mariana Gabriela gonzález-Rosales Alejandro G.Mendoza Lizbeth E.Robles-Jiménez Pilar Frutos Instituto de Ganadería de Montaña(CSIC-University of León) Finca Marzanas s/n24346 GrullerosLeónSpain Facultad de Medicina Veterinaria y Zootecnia Universidad Autónoma del Estado de MéxicoNo.100 Instituto Literario 100Col.Centro50000 TolucaEstado de MéxicoMexico.

Background:The high dependence of intensive ruminant production on soybean meal and the environmental impact of this crop encourage the search for alternative protein-rich *** use of insects seems promising,but the extent of their ruminal protein degradation is largely *** parameter has major influence not only on N utilization efficiency but also on the environmental burden of ruminant *** addition,although assessing ruminal N degradation represents a key first step to examine the potential of new feeds,it is a challenging task due to the lack of a reference *** study was conducted to investigate the potential of 4 insects(Tenebrio molitor,Zophobas morio,Alphitobius diaperinus and Acheta domesticus)as alternative protein sources for ruminants,using 3 methodologies:1)a regression technique based on the in vitro relationship between gas production and ammonia-N concentration;2)a conventional in vitro technique of batch cultures of ruminal microorganisms,based on filtering the incubation residue through sintered glass crucibles;and 3)the in situ nylon bag *** in vitro intestinal digestibility of the non-degraded protein in the rumen was also *** meal was used as a reference ***:Comparison of evaluation methods(regression,in vitro and in situ)did not allow to reliably select a single value of ruminal N degradation for the studied substrates,but all techniques seem to establish a similar ranking,with good correlations between methods,particularly between regression and in situ *** of the methodology,nitrogen from the 4 insects(with contents ranging from 81 to 112 g/kg of dry matter)did not show high ruminal degradation(41–76%),this value being always lower than that of soybean ***,the in vitro intestinal digestibility of non-degraded N was relatively high in all feeds(≥64%).Conclusion:Overall,these results support the potential of the 4 studied insects as alternative feedstu

关键词： In situ In vitro Livestock Nitrogen degradation Sheep

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mRNA levels of TLR4 and TLR5 are independent of H pylori

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World Journal of Gastroenterology 2008年第34期14卷 5306-5310页

作者： Elvira Garza-gonzález Virgilio Bocanegra-García Francisco Javier Bosques-Padilla Juan pablo Flores-Gutiérrez Francisco Moreno Guillermo Ignacio Perez-Perez Departmento de Microbiología Facultad de MedicinaUniversidad Autónoma de Nuevo León Departmento de Biología Molecular y Bioingeniería UAM Reynosa Aztlán Universidad Autónoma de Tamaulipas Hospital Universitario "Dr. José Eleuterio gonzález" Universidad Autónoma de Nuevo León Department of Medicine and Microbiology New York University School of Medicine

AIM:To determine if the presence H pylori or its viru- lence affect toll-like receptor 4 (TLR4) and TLR5 mRNA expression levels. METHODS:For the in vivo assays, gastric biopsies were obtained from 40 patients and H pylori status was determined. For the in vitro assays, human gastric adenocarcinoma mucosal cells (AGS) were cultured in the presence or absence of twelve selected H pylori strains. H pylori strains isolated from culture-positive patients and selected strains were genotyped for cagA and vacA. The cDNA was obtained from mRNA extracted from biopsies and from infected AGS cells. TLR4 and TLR5 mRNA levels were examined by real-time PCR. RESULTS: The presence of H pylori did not affect the mRNA levels of TLR4 or TLR5 in gastric biopsies. The mRNA levels of both receptors were not influenced by the vacA status (P > 0.05 for both receptors) andthere were no differences in TLR4 or TLR5 mRNA levels among the different clinical presentations/histological fi ndings (P > 0.05). In the in vitro assay, the mRNA levels of TLR4 or TLR5 in AGS cells were not influenced by the vacAs1 status or the clinical condition as-sociated with the strains (P > 0.05 for both TLR4 and TLR5). CONCLUSION: The results of this study show that the mRNA levels of TLR4 and TLR5 in gastric cells, both in vivo and in vitro, are independent of H pylori colonization and suggest that vacA may not be a significant player in the first step of innate immune recognition mediated by TLR4 or TLR5.

关键词： H pylori Toll-like receptor 4 Toll-likereceptor 5 AGS cells mRNA

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Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

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Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobato Mariam Masmudi-Martín Manuel F.López-Aranda Juan F.López-Téllez Gloria Delgado pablo Granados-Durán Celia Gaona-Romero Marta Carretero-Rey Sinforiano Posadas María E.Quiros-Ortega Zafar U.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of *** this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM *** findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dysfunction episodic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory loss regulator of G protein signaling

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