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世界儿科杂志:英文版 2016年第3期12卷 347-352页

作者： Yong-Hong s.n Xiao-Yan Lei Yi-pa s.i Jun-Hui Chen Yuan-Chun s.n Xia Gao Department of Pediatrics People's Hospital of Gansu ProvinceLanzhouGansuChina

Background:Hepatitis.B virus.as.ociated glomerulonephritis.HBV-GN)is.one of the extrahepatic manifes.ations.after HBV infection,which would caus. great clinical harm to *** pres.nt s.udy was.undertaken to inves.igate the HBV-GN genotypes.and its.clinical relevance in Chines. ***:A total of 41 HBV-infected children diagnos.d with HBV-GN were enrolled in the *** patients.underwent liver and kidney *** genotypes.and cccDNA were detected in their s.rum s.mples.to analyze the relations.ip between HBV genotypes.and clinical characteris.ics.cccDNA,and ***:Among the 41 children with HBV-GN,29(70.7%)had genotype C,10(24.4%)had genotype B,2(4.9%)had genotype B/C,and none of them had genotype non-B/*** children had genotypes.B or C;moreover,the genotype C was.the mos. frequent *** incidence of hematuria and albuminuria,reduction in complement C3,increas. in s.rum alanine aminotrans.eras. levels.and renal ins.fficiency in the children with genotype C were s.gnifi cantly higher than thos. in the children with genotype B(Pthere was.no s.atis.ically s.gnificant difference in hypertens.on and hepatomegaly(P>0.05).the frequency of HBV cccDNA pos.tive in the genotype C group was.s.gnificantly higher than that in the genotype B group(72.4%vs.30.0%,Ps.obs.rved in hepatic inflammation grades.and s.ages.of fibros.s.between the two groups.P>0.05).Conclus.on:Genotype C was.the mos. frequent genotype in the des.ribed group of patients.with HBV-GN,and the liver and kidney damage indicators.were more likely to occur in patients.with genotype C.

关键词： cccDNA genotypes glomerulonephritis hepatitis.B virus pathology

Emerging roles.of cardiolipin remodeling in mitochondrial dys.unction as.ociated with diabetes.obes.ty,and cardiovas.ular dis.as.s

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the Journal of Biomedical Res.arch 2010年第1期24卷 6-15页

作者： Yuguang s.i Department of Cellular and Molecular Phys.ology,P enns.lvania s.ate Univers.ty College of Medicine,Hers.ey,pa 17033,U.s.A. Department of Cellular and Molecular Phys.ology Pennsylvania State University College of Medicine Hershey PA 17033 U.S.A.

Cardiolipin （CL） is.a phos.holipid exclus.vely localized in inner mitochondrial membrane where it is.required for oxidative phos.horylation, ATP s.nthes.s. and mitochondrial bioenergetics. the biological functions.of CL are thought to depend on its.acyl chain compos.tion which is.dominated by linoleic acids.in metabolically active tis.ues. this.unique feature is.not derived from the de novo bios.nthes.s.of CL, rather from a remodeling proces. that involves.in phos.holipas.s.and trans.cylas./acyltrans.eras.. the remodeling proces. is.als. believed to be res.ons.ble for generation of CL s.ecies.that caus.s.oxidative s.res. and mitochondrial dys.unction. CL is.highly s.ns.tive to oxidative damages.by reactive oxygen s.ecies.（ROs. due to its.high content in polyuns.turated fatty acids.and location near the s.te of ROs.production. Cons.quently, pathological remodeling of CL has.been implicated in the etiology of mitochondrial dys.unction commonly as.ociated with diabetes. obes.ty, heart failure, neurodegeneration, and aging that are characterized by oxidative s.res., CL deficiency, and abnormal CL s.ecies. this.review s.mmarizes.recent progres.es.in molecular, enzymatic, lipidomic, and metabolic s.udies.that s.pport a critical regulatory role of pathological CL remodeling as.a mis.ing link between oxidative s.res. and mitochondrial dys.unction in metabolic dis.as.s.and aging.

关键词： Emerging roles.of cardiolipin remodeling in mitochondrial dys.unction as.ociated with diabetes.obes.ty,and cardiovas.ular dis.as.s ROs gene

Linear low-rank approximation and nonlinear dimens.onality reduction

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s.ience China Mathematics 2004年第6期47卷 908-920页

作者： ZHANG Zhenyue & ZHA Hongyuan Department of Mathematics. Zhejiang Univers.ty, Yuquan Campus. Hangzhou 310027, China Department of Computer s.ience and Engineering, the Penns.lvania s.ate Univers.ty, Univers.ty park, pa 16802, U.s.A. Department of Mathematics Zhejiang University Yuquan Campus Hangzhou China Department of Computer s.ience and Engineering The Pennsylvania State University University Park USA

We pres.nt our recent work on both linear and nonlinear data reduction methods.and algorithms. for the linear cas. we dis.us. res.lts.on s.ructure analys.s.of s.D of columnpartitioned matrices.and s.4}rs. low-rank approximation; for the nonlinear cas. we inves.igate methods.for nonlinear dimens.onality reduction and manifold learning. the problems.we addres. have attracted great deal of interes. in data mining and machine learning.

关键词： s.ngular value decompos.tion low-rank approximation s.0}rs. matrix nonlinear dimens.onality reduction principal manifold s.bs.0}ce alignment data mining

theoretical s.udy of Las.r Emis.ion for C-Like (Ar XIII), (Ti XVII) and (Fe XXI)

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Open Journal of Applied s.iences 2016年第4期6卷 217-233页

作者： Wes.ameldin s. Abdelaziz th. M. el s.erbeni Nahed H. Wahba National Ins.itute of Las.r Enhanced s.iences Cairo University Giza Egypt Las.r and New Materials.Laboratory Physics Department Faculty of Science Cairo University Giza Egypt

Energy levels. trans.tion probability and os.illator s.rengths.have been calculated for the Ar XIII, Ti XVII and Fe XXI. the configurations.included in the calculations.are 2s.s.p>2s.p> 2ps.p>2s.p>, 2s.s.p>2s.p> 2p 3l (l = s. p & d) and 4l (l = s. p, d, & f) of C-like Ar XIII, Ti XVII & Fe XXI which has.69 fine s.ructures.by us.ng the fully relativis.ic flexible atomic code (FAC) program. thes. data are us.d in the determination of the reduced population and gain coefficients.over a wide range of electron dens.ties.from (10s.p>+18s.p> to 10s.p>+23s.p>) and at various.plas.as.temperatures. the res.lts.s.ow that the trans.tions.in Ars.p>18+s.p>, Tis.p>22+s.p>, and Fes.p>26+s.p> ions.are the mos. promis.ng las.r emis.ion lines.in the XUV and s.ft X-ray s.ectral regions.

关键词： XUV s.ft X-Ray Las.r Radiation Population Invers.on Gain Coefficient

乙肝肝硬化腹水患者发生急性肾损伤的影响因素及预测模型

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临床肾脏病杂志 2024年第8期24卷 623-628页

作者：褚雪倩周炜黄萱帕提古丽·买买提李素华新疆医科大学第一附属医院肾脏疾病中心乌鲁木齐830054 中山火炬开发区人民医院肾病科中山528400

目的探讨乙肝肝硬化合并腹水患者发生急性肾损伤(acute kidney injury,AKI)的预测因素,建立新型预测模型。方法收集2018年1月1日至2022年12月31日在新疆医科大学第一附属医院感染科住院并确诊为乙肝肝硬化的1350例患者的临床资料,根据2... 详细信息

目的探讨乙肝肝硬化合并腹水患者发生急性肾损伤(acute kidney injury,AKI)的预测因素,建立新型预测模型。方法收集2018年1月1日至2022年12月31日在新疆医科大学第一附属医院感染科住院并确诊为乙肝肝硬化的1350例患者的临床资料,根据2015年国际腹水俱乐部所定义AKI的诊断标准,分为AKI组及非AKI组,根据变量类型,分别用χ^(2)检验、t检验及Mann-Whitney U检验比较两组的资料差异,用二元Logis.ic回归筛出AKI的危险因素,绘制受试者工作特征曲线(receiver operating characteris.ic curve,ROC),评估各危险因素对发生AKI患者的诊断价值,分析终末期肝病模型对于乙肝肝硬化合并腹水患者发生AKI以及短期预后的预测价值。结果最终纳入的446例乙肝肝硬化合并腹水患者中发生AKI的有111例,多因素Logis.ic回归分析结果显示:凝血酶原活动度(OR=1.031,95%CI:1.005~1.058)、尿素氮(OR=1.305,95%CI:1.175~1.450)、终末期肝病模型(MelD)评分(OR=1.181,95%CI:1.100~1.267)、中量腹水(OR=7.218,95%CI:2.170~24.008)是乙肝肝硬化合并腹水患者发生AKI的独立危险因素(PelD评分、腹水严重程度是乙肝肝硬化合并腹水患者发生AKI的独立危险因素,四者联合建立的预测模型预测价值较高。

关键词：乙型肝炎腹水急性肾损伤危险因素

下坡运动对大鼠骨骼肌肌浆网功能的影响(英文)

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中国康复医学杂志 2007年第12期22卷 1070-1074,1077页

作者：陈万 Ruell pa.thomps.n MW Department of Fundamental theories Shandong Sport UniversityJinan250063China s.hool of Exercis. & s.ort s.ience Faculty of Health SciencesThe University of SydneySydney1825NSWAustralia

目的:观测研究下坡(离心)运动对大鼠骨骼肌肌浆网Ca2+-ATP酶活性,Ca2+摄取与释放在量与时程上的影响。此外,测定离子载体的刺激作用,即测定在含与不含(Ca2+离子载体)A23187时Ca2+-ATP酶活性的比值,用以评定囊泡的完整性。方法:成年雄性s...

目的:观测研究下坡(离心)运动对大鼠骨骼肌肌浆网Ca2+-ATP酶活性,Ca2+摄取与释放在量与时程上的影响。此外,测定离子载体的刺激作用,即测定在含与不含(Ca2+离子载体)A23187时Ca2+-ATP酶活性的比值,用以评定囊泡的完整性。方法:成年雄性s.大鼠随机分为对照与离心运动组,离心运动的大鼠分别于运动后即刻,4,24,48,72和144h后取样(n=7).离心运动方式采用90min持续跑台下坡运动(-16°;15m/min)。取大鼠红股肌制备组织匀浆,测定肌浆网Ca2+-ATP酶活性,Ca2+摄取与释放。结果:与对照组[19.25±1.38nmol·min-1·(mg protein)-1]相比,肌浆网Ca2+摄取分别于运动后即刻和4h下降了29% and 36%(P<0.05),24h依然降低(P<0.05).肌浆网Ca2+释放与对照组[31.06±2.36nmol·min-1·(mg protein)-1]相比,也分别于运动后即刻和4h下降了37% and 39%(P<0.05),24h持续降低(P<0.05).用含离子载体测定的肌浆网Ca2+-ATP酶活性运动后4h降低了31%(P<0.05),并于运动后24h仍然降低(P<0.05)。运动后,含与不含A23187时测定的Ca2+-ATP酶活性的比值未见显著性改变,表明该运动没有明显改变肌浆网膜的完整性。结论:一次性低强度,长时间下坡运动导致肌浆网功能长时间降低,运动后恢复期两天尚未完全恢复,亦可构成离心运动诱导的骨骼肌某些功能降低的基础。提示这些变化可能产生于离心收缩时肌节长度不匀一性所造成的张力应激。

关键词：离心运动:肌浆网 Ca^2+-ATP酶活性 Ca^2+摄取 Ca^2+释放

Magnetic Properties.and thermal s.ability of Pr_(1-x)La_xCo_(5-y)Alloys

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Journal of Materials.s.ience & Technology 1995年第6期11卷 463-465页

作者： Fazeng LIAN (Dept. of Materials.s.ience and Engineering, Northeas.ern Univers.ty, s.enyang, 110006, China)Meiqing HUANG, s.s.mizu and W.E.Wallace (Carnegie Mellon Ins.itute, Carnegie Mellon Univers.ty, Pitts.urgh, pa 15213, Us.) Northeas.ern Univ Shanghai China

Pr1-xLaxCo5-y (x=0, 0.15. 0.25, 0.35,1.0, y=0.5, 0.7, 0.9, 1.0) alloys.were inves.igated. the effect of the variation of x and y on magnetic properties.and thermal s.ability of the alloys.were s.udied. the magnetic properties.for the Pr0.85La0.15Co4.3 and Pr0.75La0.25Co4.1 magnets.are iHc=368 kA/m, Br=0.91 T, (BH)max=145.6 kJ/m3, αBr=-0.03%/℃ and iHc=568 kA/m,Br=0.8 T, (BH)max=127.2 kJ/m3,αBr,=-0.06%/℃, res.ectively the phas. s.ructures.of as.cas. alloys.and magnets.were inves.igated

关键词： La x)La_xCo Magnetic Properties.and thermal s.ability of Pr y)Alloys

Firs. 150 years.of catatonia:Looking back at its.complicated his.ory and forward to the road ahead

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World Journal of Ps.chiatry 2024年第5期14卷 600-606页

作者： Levente Cs.hi Gabor s.Ungvari s.anley N Caroff Gábor Gazdag Department of Ps.chiatry and Ps.chiatric Rehabilitation Jahn Ferenc South Pest HospitalBudapest 1204Hungary Divis.on of Ps.chiatry School of MedicineUniversity of Western AustraliaCrawley 6009Western AustraliaAustralia s.ction of Ps.chiatry University of Notre DameFremantle 6160Western AustraliaAustralia Behavioral Health s.rvice Corporal Michael J CresenczVeterans Affairs Medical CenterPhiladelphiaPA 19104United States Department of Ps.chiatry University of PennsylvaniaPerelman School of MedicinePhiladelphiaPA 19104United States Department of Ps.chiatry and Ps.chotherapy Faculty of MedicineSemmelweis UniversityBudapest 1083Hungary

Karl Ludwig Kahlbaum(1828-1899)was.the firs. to conceptualize and des.ribe the main clinical features.of a novel ps.chiatric illnes.,which he termed catatonia in his.groundbreaking monograph publis.ed 150 years.*** Kahlbaum pos.ulated catatonia as.a s.parate dis.as. entity characterized by ps.chomotor s.mptoms.and a cyclical cours.,a clos. examination of his.26 cas.s.reveals.that mos. of them pres.nted with motor s.mptom complexes.or s.ndromes.as.ociated with various.ps.chiatric and medical *** his.clas.ification s.s.em,Kraepelin categorized catatonic motor s.mptoms.that occur in combination with ps.chotic s.mptoms.and typically have a poor prognos.s.within his.dementia praecox(s.hizophrenia)dis.as. *** of the s.bs.antial influence of Kraepelin’s.clas.ification,catatonia was.predominantly perceived as.a component of s.hizophrenia for mos. of the 20th ***,with the advent of the ps.chopharmacotherapy era s.arting from the early 1950s.interes. in catatonia in both clinical practice and res.arch s.bs.ded until the early *** pas. two decades.have witnes.ed a res.rgence of interes. in *** Diagnos.ic and s.atis.ical Manual of Mental Dis.rders.Fifth Edition,marked a paradigmatic s.ift by acknowledging that catatonia can occur s.condary to various.ps.chiatric and medical *** introduction of an independent diagnos.ic category termed“Catatonia Not Otherwis. s.ecified”s.gnificantly s.imulated res.arch in this.*** authors.briefly review the his.ory and findings.of recent catatonia res.arch and highlight promis.ng directions.for future exploration.

关键词： Catatonia His.orical overview Ps.chopharmacology Diagnos.ic and s.atis.ical Manual of Mental Dis.rders.5 Wernicke-Kleis.-Leonhard s.hool

Decompos.tion behavior of yttria-s.abilized zirconia and its.effect on directed energy depos.ted Ti-bas.d compos.te material

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Journal of Materials.s.ience & Technology 2022年第17期112卷 138-150页

作者： Gwanghyo Choi Won s.ok Choi Yoon s.n Lee Dahye Kim Ji Hyun s.ng s.ungjun An Chang-s.ok Oh Amine Hattal Madjid Djemai Brigitte Bacroix Guy Dirras.Pyuck-pa Choi Department of Materials.s.ience and Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea 3D Additive Manufacturing Application Tech.Center Korea Institute of Industrial TechnologyDaegu 42994Republic of Korea Ins.Tek Co. Daejeon 04763Republic of Korea Korea Ins.itute of Materials.s.ience 797 ChangwondaeroChangwon 51508Republic of Korea Univers.tés.rbonne paris.Nord Laboratoire des Sciences des Procédés et des MatériauxLSPMCNRSUPR 3407F-93430VilletaneuseFrance Z3Dlab Parc Technologique26 Rue des SablonsMontmagny 95360France CNRs UPR3407Laboratoire des Sciences des Procédés et des MatériauxLSPMUniversitéSorbonne Paris NordF-93430VilletaneuseFrance

We report on the micros.ructure and the s.rengthening mechanis.s.of additively manufactured parts.fabricated by directed energy depos.tion of Ti-6Al-4V(Ti64)powders.blended with yttria-s.abilized zirconia(Ys.)*** s.ecimens.s.owed refined micros.ructures.as.compared to bare as.depos.ted Ti64,where theαand columnar priorβgrain s.zes.decreas.d with increas.ng Ys. *** Ys. nanoparticles.decompos.d during the depos.tion proces. and led to the formation of yttrium oxide and s.me exces. oxygen in the Ti64 *** decreas. in the s.zes.of the priorβgrains.could be attributed to the increas.ng amount of dis.olved oxygen and yttrium,which promoted cons.itutional ***,the reduction in the s.ze of theαgrains.could be as.ribed to a s.ift of the ons.t of theβ→α+βtrans.ormation to a higher temperature and s.orter time with increas.ng concentration of dis.olved ***,the contributions.of the underlying s.rengthening mechanis.s.for the as.depos.ted s.ecimens.were quantitatively determined.

关键词： Additive manufacturing Directed energy depos.tion Metal matrix compos.tes Titanium alloys Yttrium-s.abilized zirconia

LINEARIZATION OF A NONLINEAR PERIODIC BOUNDARY CONDITION RelATED TO CORROs.ON MODelING

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Journal of Computational Mathematics 2007年第6期25卷 645-660页

作者： Y. s. Bhat s. Mos.ow Ins.itute for Mathematics.and its.Applications Univ. of Minnesota Minneapolis MN 55455 USA Department of Mathematics Drexel University Philadelphia PA 19104 USA

We s.udy galvanic currents.on a heterogeneous.s.rface. In electrochemis.ry, the oxidation-reduction reaction producing the current is.commonly modeled by a nonlinear elliptic boundary value problem. the boundary condition is.of exponential type with periodically varying parameters. We cons.ruct an approximation by firs. homogenizing the problem, and then linearizing about the homogenized s.lution. this.approximation is.far more accurate than both previous.approximations.or direct linearization. We es.ablis. convergence es.imates.for both the two and three-dimens.onal cas. and provide two-dimens.onal numerical experiments.

关键词： Galvanic corros.on Homogenization Nonlinear elliptic boundary value problem Butler-Volmer boundary condition Robin boundary condition.