检索结果-南通市图书馆

ASPETTI QUALI-QUANTITATIVI DELLE RISORSE IDRICHE SOTTERRANEE DEL BRESCIANO

Natural Disaster Reduction in China 1993年第1期 21-52页

作者： pier luigi vercesi Dipartimento

RIASSUNTO-Vengono compendiati gli aspetti idrogeologici della provincia di Brescia attraverso l’anali-si sintetica delle she principali caratteristiche geologiche e *** quadro geologico tratteggiato definisce i lineamenti della regione in studio nei suoi aspetti orografi-ci,descrivendo i vari ambiti:montani,dei conoidi,vallivi,morenici e di pianura,evidenziando i tipilitologici presenti nelle varie zone che fungono da serbatoi e da mezzi trasmissivi della risorsa *** detti corpi vengono riportate valutazioni sui principali parametri idrogeologici al finedi caratterizzare le modalità della circolazione idrica al loro interno e di definirne il grado di vulnerabilità.La caratterizzazione generale che viene fornita compendia pertanto gli elementi salienti della zonaesaminata,utilizzando peraltro valori e informazioni di carattere puntuale desunti da aree campione rap-presentative,attraverso l’acquisizione di dati locali mediante specifici e dettagliati *** complesso degli elementi conoscitivi di carattere generale the sono forniti,e che rappresentanoun preliminare momento fondamentale della ricerca,si evince la necessità di acquisire dati puntuali(infor-mazioni sui circuiti idrici,sul quadro di fratturazione e fessurazione,sulla distribuzione spaziale dellapermeabilità e porosità delle rocce,ecc.)che costituiscono i pilastri su cui basare modelli matematicidi simulazione,al fine di arrivare ad una completa ed esauriente conoscenza degli *** conseguenza le caratteristichc litologiche e tettoniche di un’area sono gli elementi che rendonopossibile la ricostruzione idrogeologica di una determinata zona e che permettono,attraverso opportuneelaborazioni quali modelli ed integrazioni(localizzazione dei punti d’acqua,dei centri di pericolo ecc.),di definire la potenzialità idrica,il quadro di vulnerabilità delle risorse,l’evoluzione dei fenomeni dieventuali *** and quantitative aspects of water resources in

关键词：工人前口日月

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

I TRAVERTINI DI CARVANNO(Brescia)

引用

Natural Disaster Reduction in China 1985年第1期 3-26页

作者： CARLO BARONI pier luigi vercesi Museo Civico di Scienze Naturali di Brescia 《frequentatore》del Dipartimento di Scienze della Terra dell'Universiàdi Pavia. Dipartimentodi Scienze della Terra dell'universitàdi pavia.

The travertine of Carvanno(Brescia)-The lithofacies of travertine of the Carvanno area aredescribed in *** deposits form the core of《Morphological Units》located at different altitudes andformed in different times during the *** deposition of the travertine is probably,from the evi-dence of morphological and morphostructural analyses,connected with the circulation of thermomineral wa-ters rising through tectonic contacts on the right of the Degagna *** subsequent levelling to terracesis due to variations in the base level of the rivers,connected with tectonic movements.

关键词： Pr La Pi I TRAVERTINI DI CARVANNO Brescia

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

IL RETICO DEL *** E DELLA PIETRA GRANDE(Madonna di Campiglio)CARATTERI STRATIGRAFICO-SEDIMENTOLOGICI E CONSIDERAZIONI PALEOGEOGRAFICHE

引用

Natural Disaster Reduction in China 1993年第1期 5-20页

作者： CECILIA PASQUINI pier luigi vercesi Dipartimento di Scienze della Terra Università

RIASSUNTO-Sono stati analizzati i depositi retici affioranti nella parte nord-occidentale delle Dolomitidi Brenta,che sono stati suddivisi in 2 formazioni di nuova istituzione:la Formazione del Graffer eil Calcare degli Orti della *** le formazioni presentano caratteristiche intermedie tra lecoeve unità lombarde,caratterizzate da potentissime alternanze calcareo-argillose,e quelle esclusivamentecarbonatiche in facies di Dolomia Principale che si svilupparono nell’area *** poi brevemen-te illustrati i principali disturbi tettonici rilevati;tra questi il più importante sembra essere costituitodalla Linea della Vedretta dei Camosci,faglia diretta impostatasi nel Lias,che ha determinato l’abbassa-mento del blocco *** considerazioni di ordine paleogeografico relative al Retico hanno porta-to a individuare una conformazione a rampa deposizionale del bacino,determinata da una serie di fagliedirette,con una zona di basso relativo a *** *** and Pietra Grande Rhaetian(Madonna di Campiglio).Stratigraphic-sedimentological characters and paleogeographic *** so-called《Rhaetian》deposits ofthe north-west area of the Dolomiti di Brenta(western Trentino region,Southern Alps)are *** are subdivided into two new formations:the《Formazione del Graffer》and the《Calcare degliOrti della Regina》.The lower unit(Formazione del Graffer),about 100 metres thick,is very rich inmarl and *** upper formation(Calcare degli Orti della Regina),about 200 metres thick,chieflyconsists of limestone and dolomite and it is characterized by peritidal shallowing-upward cyclicity,whithsubtidal fossiliferous bioturbated limestone overlain by supratidal stromatolitic *** the forma-tions exhibit intermediate characters between the coeval Lombardian sequences to the west,and the Vene-tian sequences to the *** former is characterized by a very thick succession partly basinal in nature,and consists of alternations of limestone

关键词：刀刃

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unlocking the versatile potential:Adipose-derived mesenchymal stem cells in ocular surface reconstruction and oculoplastics

引用

World Journal of Stem Cells 2024年第2期16卷 89-101页

作者： pier luigi Surico Anna Scarabosio Giovanni Miotti Martina Grando Carlo Salati pier Camillo Parodi Leopoldo Spadea Marco Zeppieri Schepens Eye Research Institute of Mass Eye and Ear Harvard Medical SchoolBostonMA 02114United States Department of Ophthalmology Campus Bio-Medico UniversityRome 00128Italy Department of Plastic Surgery University Hospital of UdineUdine 33100Italy Department of Internal Medicine Azienda Sanitaria Friuli OccidentaleSan Vito al Tagliamento 33078Italy Department of Ophthalmology University Hospital of UdineUdine 33100Italy Eye Clinic Policlinico Umberto I“Sapienza”University of RomeRome 00142Italy

This review comprehensively explores the versatile potential of mesenchymal stem cells(MSCs)with a specific focus on adipose-derived *** and oculoplastic surgery,encompassing diverse procedures for ocular and periocular enhancement,demands advanced solutions for tissue restoration,functional and aesthetic refinement,and *** immunomodulatory,regenerative,and healing capacities of MSCs,this review underscores the potential use of adipose-derived MSCs as a cost-effective alternative from bench to bedside,addressing common unmet needs in the field of reconstructive and regenerative surgery.

关键词： Stem cells Adipose stem cell Ocular therapy Oculoplastics Regenerative

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Successful treatment of acute liver failure due to Wilson’s disease: Serendipity or fortuity?

引用

World Journal of Hepatology 2024年第8期16卷 1111-1119页

作者： Valeria Delle Cave Fabiola Di Dato pier luigi Calvo Maria Immacolata Spagnuolo Raffaele Iorio Department of Translational Medical Science Section of PediatricsUniversity of Naples Federico IINaples 80131Italy Pediatric Gastroenterology Unit Regina Margherita Children's HospitalAzienda Ospedaliera-Universitaria Cittàdella Salute e della ScienzaTurin 10126Italy

BACKGROUND Acute liver failure(ALF)may be the first and most dramatic presentation of Wilson’s disease(WD).ALF due to WD(WD-ALF)is difficult to distinguish from other causes of liver disease and is a clear indication for liver *** is no firm recommendation on specific and supportive medical treatment for this *** To critically evaluate the diagnostic and therapeutic management of WD-ALF patients in order to improve their survival with native *** A retrospective analysis of patients with WD-ALF was conducted in two pediatric liver units from 2018 to *** During the study period,16 children(9 males)received a diagnosis of WD and 2 of them presented with *** first was successfully treated with an unconventional combination of low doses of D-penicillamine and zinc plus steroids,and survived without liver *** second,exclusively treated with supportive therapy,needed a hepatotransplant to overcome *** Successful treatment of 1 WD-ALF patient with low-dose D-penicillamine and zinc plus steroids may provide new perspectives for management of this condition,which is currently only treated with liver transplantation.

关键词： Fulminant liver failure Copper Chelator Zinc Steroids Liver transplantation Autoimmune hepatitis Prognostic score 24 hour-urinary copper excretion Native liver

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Whole-eye transplantation: Current challenges and future perspectives

引用

World Journal of Transplantation 2024年第2期14卷 28-39页

作者： Anna Scarabosio pier luigi Surico Vlad Tereshenko Rohan Bir Singh Carlo Salati Leopoldo Spadea Glenda Caputo pier Camillo Parodi Caterina Gagliano Jonathan M Winograd Marco Zeppieri Department of Plastic Surgery University Hospital of UdineUdine 33100Italy Department of Plastic Surgery Massachusetts General HospitalHarvard Medical SchoolBostonMA 02114United States Schepens Eye Research Institute of Mass Eye and Ear Harvard Medical SchoolBostonMA 02114United States Department of Ophthalmology University Hospital of UdineUdine 33100Italy Eye Clinic Policlinico Umberto I"Sapienza"University of RomeRome 00142Italy Department of Medicine and Surgery University of Enna"Kore"Enna 94100Italy Eye Clinic Catania University San Marco Hospital Viale Carlo Azeglio Ciampi 95121 CataniaItaly

Whole-eye transplantation emerges as a frontier in ophthalmology,promising a transformative approach to irreversible *** advancements,formidable challenges *** of donor eye viability post-enucleation necessitates meticulous surgical techniques to optimize retinal integrity and ganglion cell *** the inhibitory milieu of the central nervous system for successful optic nerve regeneration remains elusive,prompting the exploration of neurotrophic support and immunomodulatory *** tolerance,paramount for graft acceptance,confronts the distinc-tive immunogenicity of ocular tissues,driving research into targeted immunosup-pression *** and legal considerations underscore the necessity for stringent standards and ethical *** collaboration and ongoing research endeavors are imperative to navigate these ***,stem cell therapies,and precision immunomodulation represent promising avenues in this ***,the aim of this review is to critically assess the current landscape of whole-eye transplantation,elucidating the challenges and advancements while delineating future directions for research and clinical *** concerted efforts,whole-eye transplantation stands to revolu-tionize ophthalmic care,offering hope for restored vision and enhanced quality of life for those afflicted with blindness.

关键词： Eye Transplantation Optic nerve Nerve regeneration Immunological tolerance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fat or fillers:The dilemma in eyelid surgery

引用

World Journal of Clinical Cases 2024年第17期12卷 2951-2965页

作者： Giovanni Miotti Luca De Marco Davide Quaglia Martina Grando Carlo Salati Leopoldo Spadea Caterina Gagliano Mutali Musa pier luigi Surico pier Camillo Parodi Marco Zeppieri Department of Plastic Surgery University Hospital of UdineUdine 33100Italy Department of Internal Medicine Azienda Sanitaria Friuli OccidentaleSan Vito al Tagliamento 33078Italy Department of Ophthalmology University Hospital of UdineUdine 33100Italy Eye Clinic Policlinico Umberto I“Sapienza”University of RomeRome 00142Italy Department of Medicine and Surgery University of Enna“Kore”Enna 94100Italy Eye Clinic Catania University San Marco Hospital Viale Carlo Azeglio CiampiCatania 95121Italy Department of Optometry University of BeninBenin 300283Nigeria Department of Ophthalmology Africa Eye Laser CentreKm 7Benin 300105Nigeria Schepens Eye Research Institute of Mass Eye and Ear Harvard Medical SchoolBostonMA 02114United States

The aging of the periocular region has always aroused great interest.A fresh,young,and attractive sight determined an ever-greater attention to surgical and non-surgical techniques to obtain this *** particular,the change in the concept of a young look,considered then“full”,led to the increasing use of surgical(fat grafting)or medical(hyaluronic acid)filling *** rejuvenation became increasingly popular in the field of cosmetic treatments,with a focus on achieving a youthful and refreshed *** the various techniques available,the choice between using fat grafting or fillers presented a clinical *** particular,what surgery considered of fundamental importance was a long-lasting result over *** the other hand,aesthetic medicine considered it fundamental not to have to resort to invasive *** what was the reality?Was there one path better than the other,and above all,was there a better path for patients?The minireview aims to explore the physiopathology,diagnosis,treatment options,prognosis,and future studies regarding this *** analyzed the literature produced in the last 20 years comparing the two *** literature reveals advancements in biomaterials,stem cell research and tissue engineering held promise for further enhancing the field of eyelid *** choice between fat grafting and fillers in eyelid cosmetic treatments presented a clinical *** physiopathology,accurately diagnosing eyelid aging,exploring treatment options,assessing prognosis,and conducting future studies were essential for providing optimal care to patients seeking eyelid rejuvenation.

关键词： Stem cells Adipose stem cell Ocular therapy Oculoplastics Regenerative

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

β_(2) and α_(2) adrenergic receptors mediate the proneurogenic in vitro effects of norquetiapine

引用

Neural Regeneration Research 2021年第10期16卷 2041-2047页

作者： Valeria Bortolotto pier luigi Canonico Mariagrazia Grilli Laboratory of Neuroplasticity University of Piemonte OrientaleNovaraItaly Department of Pharmaceutical Sciences University of Piemonte OrientaleNovaraItaly

Positive modulation of adult hippocampal neurogenesis may contribute to the therapeutic effects of clinically relevant antidepressant drugs,including atypical ***,an antipsychotic which represents a therapeutic option in patients who are resistant to classical antidepressants,promotes adult hippocampal neurogenesis in preclinical ***,the key active metabolite of quetiapine in humans,has a distinctive receptor profile than the parent *** drug is indeed a high affinity norepinephrine transporter inhibitor and such activity has been proposed to contribute to its antidepressant *** present,no information is available on the effects of norquetiapine on adult *** extensively investigated the activity of quetiapine and norquetiapine on adult murine neural stem/progenitor cells and their ***,selective antagonists for β_(2)/α_(2) adrenergic receptors allowed us to evaluate if these receptors could mediate quetiapine and norquetiapine *** demonstrated that both drugs elicit in vitro proneurogenic effects but also that norquetiapine had distinctive properties which may depend on its ability to inhibit norepinephrine transporter and involve β_(2)/α_(2) adrenergic *** care and experimental procedures were approved by the Institutional Animal Care and Use Committees(IACUC)at University of Piemonte Orientale,Italy(approval No.1033/2015PR)on September 29,2015.

关键词： adrenergic receptors adult neurogenesis antidepressants antipsychotics depression neural progenitor cells norquetiapine quetiapine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Follicular lymphoma:the diminishing role of chemotherapy

引用

Journal of Cancer Metastasis and Treatment 2022年第1期8卷 393-411页

作者： Beatrice Casadei Laura Nanni Ginevra Lolli pier luigi Zinzani IRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia“Seràgnoli”Bologna 40138Italy Dipartimento di Medicina Specialistica Diagnostica e SperimentaleUniversitàdi BolognaBologna 40138Italy

Follicular lymphoma(FL)is the most common indolent non-Hodgkin lymphoma,accounting for 70%of cases in Western *** this unique name,FL is an extremely heterogeneous disease,both clinically and *** basis of FL heterogeneity lies in the different biological pathways which can be activated,because of the variety of gene mutations that can ***,there is a growing interest in the knowledge of these activated pathways,which is also testified by the presence of a new model that incorporates FL mutations to define patient’s prognosis(m7-FLIPI).These evaluations are also appealing because of the recent possibility of using“targeted therapies”.Targeted therapies are new tools,currently applicable in the setting of relapse/refractory(R/R)disease,where we can find a great variety of“chemo-free”*** in other hematologic malignancies,“cellular therapy”enriches FL drug scenario,including T-cell dependent bispecific antibodies and chimeric antigen receptor(CAR)*** FL heterogeneity is the basis of the difference in therapeutic efficacy and disease course among patients,the hope for the future is to understand FL biology more deeply,to better comprehend how to obtain more representative samples and pre-treatment prognostic information in order to individualize the treatment strategy as early as frontline therapy.

关键词： Follicular lymphoma POD24 target therapies chemo-immunotherapy biological heterogeneity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Externalized conductors and insulation failure in Biotronik defibrillator leads: History repeating or a false alarm?

引用

World Journal of Clinical Cases 2017年第2期5卷 27-34页

作者： Elia De Maria Ambra Borghi Lorenzo Bonetti pier luigi Fontana Stefano Cappelli Cardiology Unit Ramazzini Hospital

Conductor externalization and insulation failure are frequent complications with the recalled St. Jude Medical Riata implantable cardioverter-defibrillator(ICD) leads. Conductor externalization is a "unique" failure mechanism: Cables externalize through the insulation("inside-out" abrasion) and appear outside the lead body. Recently, single reports described a similar failure also for Biotronik leads. Moreover, some studies reported a high rate of electrical dysfunction(not only insulation failure) with Biotronik Linox leads and a reduced survival rate in comparison with the competitors. In this paper we describe the case of a patient with a Biotronik Kentrox ICD lead presenting with signs of insulation failure and conductor externalization at fluoroscopy. Due to the high risk of extraction we decided to implant a new lead, abandoning the damaged one; lead reimplant was uneventful. Subsequently, we review currently available literature about Biotronik Kentrox and Linox ICD lead failure and in particular externalized conductors. Some single-center studies and a nonprospective registry reported a survival rate between 88% and 91% at 5 years for Linox leads, significantly worse than that of other manufacturers. However, the preliminary results of two ongoing multicenter, prospective registries(GALAXY and CELESTIAL) showed 96% survival rate at 5 years after implant, well within industry standards. Ongoing data collection is needed to confirm longer-term performance of this family of ICD leads.

关键词： Implantable cardioverter defibrillator Biotronik implantable cardioverter defibrillator lead Externalized conductors Insulation failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：