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Passive seismic experiment and ScS wave splitting in the southwestern subbasin of South China Sea

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Chinese Science Bulletin 2012年第25期57卷 3381-3390页

作者： RUAN AiGuo LI JiaBiao LEE ChaoShing QIU XueLin pan shaojun The Second Institute of Oceanography State Oceanic AdministrationHangzhou 310012China Institute of Applied Geosciences Taiwan Ocean UniversityKeelung 20224China South China Sea Institute of Oceanology Chinese Academy of SciencesGuangzhou 510301China

The seismic experiment of 3D array of OBS in the southwestern sub-basin of the South China Sea(SCS) is briefly introduced in this *** data analysis of broadband OBS shows that totally 93 earthquakes with magnitude of Ms 6.0-6.9 and 10 earthquakes with magnitude above Ms 7.0 were recorded in high quality during this experiment,especially the catastrophic earthquake Ms 9.0 occurred in the east sea area of Japan on March 11,*** anisotropy parameters inversion of ScS wave of four events above Ms 7.0 indicates that the fast direction of shear wave is N58°E parallel to the ceased spreading ridge of the southwestern sub-basin of SCS(the slow direction is S35°E perpendicular to the spreading ridge),which means the spreading ridge is under compressing stress at present and the cessation of seafloor spreading is related to such stress field as well.

关键词：地震实验中国南海西南海盆分裂三维数组数据分析参数反演各向异性

GSH-triggered sequential catalysis for tumor imaging and eradication based on star-like Au/Pt enzyme carrier system

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Nano Research 2020年第1期13卷 160-172页

作者： Amin Zhang Qian Zhang Gabriel Alfranca shaojun pan Zhicheng Huang Jin Cheng Qiang Ma Jie Song Yunxiang pan Jian Ni Lijun Ma Daxiang Cui Institute of Nano Biomedicine and Engineering Shanghai Engineering Research Center for Intelligent Diagnosis and Treatment InstrumentDepartment of Instrument Science and EngineeringSchool of Electronic Information and Electrical EngineeringShanghai Jiao Tong University800 Dongchuan RDShanghai200240China National Center for Translational Medicine Collaborative Innovational Center for System BiologyShanghai Jiao Tong University800 Dongchuan RoadShanghai200240China School of Biomedical Engineering Shanghai Jiao Tong UniversityShanghai200240China Instituto de Ciencia de Materiales de Aragón(ICMA) CSIC/Universidad de ZaragozaC/Pedro Cerbuna 1250009ZaragozaSpain Department of Tumor Xintai People’s HospitalXintai271200China Department of Tumor in Tongren Hospital Shanghai Jiao Tong University School of Medicine1111 XianXia RoadShanghai200336China

Distinctively different metabolism between tumor cells and normal cells endows tumor tissues unique *** this regard,we have successfully prepared a sequential catalytic platform based on Au/Pt star for tumor *** multifunctional probes consisted of a gold/platinum star-shaped core(Au/Pt star)conjugated with a GSH-sensitive disulfide bond(S–S),a targeting ligand(rHSA-FA),a near-infrared fluorophore(IR780)and glucose oxidase(GOx).When systemically administered in a xenografted murine model,the probes specifically targeted the tumor *** the disulfide linker was cleaved by intracellular GSH,the IR780 molecules could be released for photo-thermal therapy&photodynamic therapy(PTT&PDT)and ***,the Pt nanolayer of the Au/Pt star and the GOx formed a sequential catalytic system:GOx effectively catalyzed intracellular glucose by consuming oxygen to generate H2O2 and enhance the local acidity,and the Pt layer exhibited peroxidase-like property to catalyze H2O2 producing toxic·OH for tumor oxidative *** we demonstrated that our probes simultaneously possessed a GSH-sensitive release,real-time imaging ability,and synergetic cancer starving-like therapy/enzyme oxidative therapy/PTT/PDT features,which provides a potential strategy for effective tumor theragnostic.

关键词： Au/Pt star GSH-responsive GOx peroxidase sequential nanocatalyst cancer starving-like therapy enzyme oxidative therapy photo-thermal therapy&photodynamic therapy(PTT&PDT)

Human natural killer cells for targeting delivery of gold nanostars and bimodal imaging directed photothermal/photodynamic therapy and immunotherapy

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Cancer Biology & Medicine 2019年第4期16卷 756-770页

作者： Bin Liu Wen Cao Jin Cheng Sisi Fan shaojun pan Lirui Wang Jiaqi Niu Yunxiang pan Yanlei Liu Xiyang Sun Lijun Ma Jie Song Jian Ni Daxiang Cui Institute of Nano Biomedicine and Engineering Shanghai Engineering Research Centre for Intelligent Diagnosis and Treatment InstrumentDepartment of Instrument Science and EngineeringSchool of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240China National Center for Translational Medicine Collaborative Innovational Center for System BiologyShanghai Jiao Tong UniversityShanghai 200240China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200030China School of Biomedical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Oncology Tongren HospitalShanghai Jiao Tong University School of MedicineShanghai 200336China

Objective:To construct a novel nanoplatform GNS@CaCO3/Ce6-NK by loading the CaCO3-coated gold nanostars(GNSs)with Chlorin e6 molecules(Ce6)into human peripheral blood mononuclear cells(PBMCs)-derived NK cells for tumor targeted ***:GNS@CaCO3/Ce6 nanoparticles were prepared and characterized by TEM and *** cell surface markers and cytokines secretion of NK cells before and after loading the GNS@CaCO3/Ce6 nanoparticles were detected by Flow Cytometry(FCM)and *** of the GNS@CaCO3/Ce6-NK cells on A549 cancer cells was determined by FCM and *** fluorescent signals of GNS@CaCO3/Ce6-NK cells were detected via Confocal laser scanning microscopic(CLSM)and FCM at different time *** ROS generation of GNS@CaCO3/Ce6-NK cells under laser irradiation were examined by *** distribution of GNS@CaCO3/Ce6-NK in A549 tumor-bearing mice were observed by fluorescence imaging and PA *** combination therapy of GNS@CaCO3/Ce6-NK under laser irradiation were investigated on tumor-bearing ***:The coated CaC03 shell on the surface of GNSs exhibited prominent delivery and protection effect of Ce6 during the cellular uptake *** as-prepared multifunctional GNS@CaCO3/Ce6-NK cells possessed bimodal functions of fluorescence imaging and photoacoustic *** as-prepared multifunctional GNS@CaCO3/Ce6-NK cells could actively target tumor tissues with the enhanced photothermal/photodynamic therapy and ***:The GNS@CaCO3/Ce6-NK shows effective tumor-targeting ability and prominent therapeutic efficacy toward lung cancer A549 tumor-bearing *** fully utilizing the features of GNSs and NK cells,this new nanoplatform provides a new synergistic strategy for enhanced photothermal/photodynamic therapy and immunotherapy in the field of anticancer development in the near future.

关键词： Gold nanostars natural killer cells photothermal therapy photodynamic therapy immunotherapy

装配式建筑工程钢结构施工技术和施工管理的措施

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智能城市应用 2024年第8期7卷 43-45页

作者：潘少军浙江航兴建设集团有限公司浙江湖州313000

装配式建筑工程是一种新型的建筑方式,它通过工厂化生产、装配式施工,实现了建筑的标准化、模块化和工业化。在装配式建筑工程中,钢结构施工是关键环节。钢结构施工的质量好坏直接影响到整个建筑工程的质量。文中主要探讨了装配式建筑... 详细信息

装配式建筑工程是一种新型的建筑方式,它通过工厂化生产、装配式施工,实现了建筑的标准化、模块化和工业化。在装配式建筑工程中,钢结构施工是关键环节。钢结构施工的质量好坏直接影响到整个建筑工程的质量。文中主要探讨了装配式建筑工程中钢结构施工技术和施工管理的措施,以提高施工质量和效率。因此,研究装配式建筑工程中钢结构施工技术和施工管理的措施具有重要的意义。

关键词：装配式建筑钢结构施工施工管理

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浙西北建德市溶洞资源价值评价

中国地质调查 2024年第2期11卷 72-80页

作者：潘少军张建芳陈小友浙江省地质院浙江杭州311200

溶洞作为一种地质遗迹资源,对其开展定量评价可以更好地实施保护和利用。在对建德市溶洞资源开展调查研究的基础上,分析建德市溶洞形成的地质背景,对区域内溶洞特征进行分类统计,运用层次分析法构建符合当地溶洞特征的价值评价体系。通... 详细信息

溶洞作为一种地质遗迹资源,对其开展定量评价可以更好地实施保护和利用。在对建德市溶洞资源开展调查研究的基础上,分析建德市溶洞形成的地质背景,对区域内溶洞特征进行分类统计,运用层次分析法构建符合当地溶洞特征的价值评价体系。通过结合定量分析与溶洞旅游的实际情况,对建德市溶洞开展了全面评价,根据评价指标要素对每个溶洞进行分值量化。以浙江省已开发溶洞为背景,对溶洞的开发价值进行了简要分析,推荐黑洞作为优先开发备选点,神仙洞、金洲仙姑洞、九仙洞、马头山洞、前山洞、戴家仙姑洞等作为次级开发备选点,并选取黑洞作为典型溶洞,从形态、岩溶景观等方面对其进行了深入介绍。评价分析结果可为溶洞的规划与开发利用提供基础资料,为建德市的旅游业发展提供新的备选地。根据溶洞资源特征及评价结果,将溶洞划分了不同的保护级别,可为当地开展溶洞分类保护工作起到支撑作用。

关键词：溶洞地质特征开发价值价值评价分级保护建德市

浙江建德市耕地表层土壤硒分布、来源及生态效应

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现代地质 2022年第3期36卷 953-962页

作者：刘健汪一凡林钟扬潘少军浙江省地质调查院浙江杭州311203

硒是重要的生命元素之一,对动物及人体健康具有重要意义。系统总结了建德市耕地表层土壤硒地球化学特征,分析了土壤硒的分布规律及其与黑色岩系之间的成因联系,探讨了黑色岩系富硒机制,研究了水稻植株中硒富集规律。结果表明,建德市耕... 详细信息

硒是重要的生命元素之一,对动物及人体健康具有重要意义。系统总结了建德市耕地表层土壤硒地球化学特征,分析了土壤硒的分布规律及其与黑色岩系之间的成因联系,探讨了黑色岩系富硒机制,研究了水稻植株中硒富集规律。结果表明,建德市耕地表层土壤硒含量介于0.06~11.5 mg/kg之间,均值为0.35 mg/kg,不同地质背景、成土母质、土壤类型中土壤硒含量差异显著。根据土壤硒和重金属含量,圈出清洁富硒土壤2647 hm^(2),主要分布于寒武系灰岩、碳质页岩、钙质泥岩等岩石出露区,指示土壤富硒与这套寒武系“黑色岩系”有密切关系。古沉积学研究认为,黑色岩系形成于缺氧滞水的沉积环境,富含有机质的海底沉积物大量吸附来自地幔的硒,成岩后形成富含硒等元素的黑色岩系。水稻根系土中硒形态组成分析表明,醋酸溶解态硒占比较小,残渣态占比较大,说明水稻根系土中硒可利用性较低。稻米、莲子、草莓及其根系土采样分析表明,稻米对土壤硒的富集系数最高,水稻植株中硒含量具有根>叶>茎≈籽实的特征。

关键词：硒元素黑色岩系生态效应建德市

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聚合物/铝界面的粘附作用

高分子学报 1989年第1期 103-108页

作者：黄绍钧潘慧铭刘杰华南工学院材料科学研究所

本文测算了经表面处理的铝合金的表面能,通过FT-IR表面分析及EDXA成份分析等研究了表面能变化的因素,以TEM观察了表面形貌。另外,测定了环氧及EVA胶粘剂对铝合金的剪切粘度,讨论了它与表面性质的关系。

关键词：聚合物铝合金表面能粘附

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低功耗微型电源管理IC的基准源设计

微电子学 2014年第4期44卷 451-455页

作者：汪倩邓婉玲黄君凯潘少俊饶远暨南大学信息科学技术学院电子工程系广州510632

针对智能手机功能集成度与功耗的矛盾,提出了一种适用于射频和基带的微型电源管理IC新架构,并基于MOS器件的亚阈值特性,详细地给出其中具有低功耗零温漂的电流基准及电压基准电路的设计。基于TSMC 0.25μm CMOS混合信号工艺,通过Cadenc... 详细信息

针对智能手机功能集成度与功耗的矛盾,提出了一种适用于射频和基带的微型电源管理IC新架构,并基于MOS器件的亚阈值特性,详细地给出其中具有低功耗零温漂的电流基准及电压基准电路的设计。基于TSMC 0.25μm CMOS混合信号工艺,通过Cadence公司的Spectre软件进行仿真验证。结果表明,在-20℃-110℃范围温度内,基准源在工作电压为3.6 V时,可输出50 nA±0.25 nA的基准电流;当电源电压在0.8-4 V变化时,可提供稳定的0.671 V基准电压,其中在0℃-50℃的常温内,具有1.49×10^-5／℃的温度系数；在0～100kHz频率范围内，基准源的PSRR可达到-74dB。

关键词：微型电源管理IC 亚阈值低功耗基准源

长江三角洲平原南部上新世以来古环境演变及多重地层划分

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地球与环境 2019年第4期47卷 464-476页

作者：林钟扬金翔龙管敏琳潘少军赵旭东中国地质大学资源学院武汉430074 自然资源部第二海洋研究所国家海洋局海底科学重点实验室杭州310012 中国煤炭科工集团煤科集团杭州研究院杭州311201 浙江省地质调查院杭州311203

对长江三角洲平原BZK01钻孔进行沉积物14C测年、粒度、磁学、孢粉和微体古生物分析,结合伽玛测井、岩性地层讨论了上新世以来钻孔揭示的孢粉组合、沉积环境演化、沉积相和古气候特征,建立了钻孔的第四纪多重地层划分对比框架.结果表明,... 详细信息

对长江三角洲平原BZK01钻孔进行沉积物14C测年、粒度、磁学、孢粉和微体古生物分析,结合伽玛测井、岩性地层讨论了上新世以来钻孔揭示的孢粉组合、沉积环境演化、沉积相和古气候特征,建立了钻孔的第四纪多重地层划分对比框架.结果表明,受原始地形地貌、海平面变化、海陆变迁、古气候冷暖更替及新构造运动的影响,研究区上新世以来经历了多次环境变化.钻孔自下而上揭示岩性地层依次为基岩长河组、新近纪-第四纪沉积的嘉兴组、前港组、东浦组、宁波组、镇海组,孢粉组合可划分出16个孢粉带,按暖期温暖潮湿-冷期寒冷干燥古气候旋回变化的周期律,BZK01钻孔反映该区域共存在7个古气候旋回.建立的钻孔多重地层划分对比揭示151.9~278.0 m为河流相和河湖相交替沉积的上新世-早更新世时期,存在两个气候旋回过程;83.5~151.9 m为河流相-河湖相-浅湖相沉积环境的中更新世,包含两个气候旋回过程;15.4~83.5 m为晚更新世,沉积环境自下而上为河口相-河湖相-潮坪相-滨海相-河湖相,与王店海侵-杭州海侵时期对应,包括两个气候旋回;0~15.4 m为河口相-河湖相-泻湖相沉积环境的全新世,对应富阳海侵,包括一个气候旋回.

关键词：长江三角洲平原第四纪沉积相古环境多重地层划分