检索结果-南通市图书馆

An integrated microfluidic platform for nucleic acid testing

Microsystems & nanoengineering 2024年第3期10卷 181-194页

作者： Antao Sun petra Vopařilová Xiaocheng Liu Bingqian Kou TomášŘezníček TomášLednický Sheng ni JiříKudr Ondřej Zítka Zdenka Fohlerová petr pajer Haoqing Zhang pavel neužil Ministry of Education Key Laboratory of Micro and nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical University127 West Youyi RoadXi’anShaanxi 710072P.R.China Department of Chemistry and Biochemistry Mendel University in BrnoZemědělská161300 BrnoCzech Republic ITD Tech s.r.o Osvoboditelů100573581 BohumínCzech Republic Central European Institute of Technology Brno University of TechnologyPurkyňova 123Brno 61200Czech Republic Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SARChina Department of Microelectronics Faculty of Electrical Engineering and CommunicationBrno University of TechnologyTechnická3058/10Brno 61600Czech Republic Military Health Institute U Vojenskénemocnice 120016200 Praha 6Czech Republic The Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and TechnologyXi’an Jiaotong UniversityXi’anShaanxi 710049P.R.China Bioinspired Engineering and Biomechanics Center(BEBC) Xi’an Jiaotong UniversityXi’an 710049P.R.China

This study presents a rapid and versatile low-cost sample-to-answer system for SARS-CoV-2 *** system integrates the extraction and purification of nucleic acids,followed by amplification via either reverse transcriptionquantitative polymerase chain reaction(RT–qpCR)or reverse transcription loop-mediated isothermal amplification(RT–LAMp).By meeting diverse diagnostic and reagent needs,the platform yields testing results that closely align with those of commercial RT-LAMp and RT‒qpCR *** advantages of our system include its speed and *** assay is completed within 28 min,including sample loading(5 min),ribonucleic acid(RnA)extraction(3 min),and RT-LAMp(20 min).The cost of each assay is≈$9.5,and this pricing is competitive against that of Food and Drug Administration(FDA)-approved commercial *** some RnA loss during on-chip extraction is observed,the platform maintains a potential limit of detection lower than 297 *** makes the system particularly useful in environments where centralized laboratories are either unavailable or inconveniently *** key feature is the platform’s versatility,allowing users to choose between RT‒qpCR or RT‒LAMp tests based on specific requirements.

关键词： testing maintain versatile

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice

引用

Asian pacific Journal of Tropical Biomedicine 2024年第5期14卷 199-206页

作者： Lucelina S.Araújo Bruno B.Silva Eduarda n.F.n.Santos Arnaldo S.Bezerra Samuel S.Frota Assis R.Montenegro Eridan O.p.T.Florean Maurício Fvan Tilburg Maria Izabel F.Guedes Laboratory of Biotechnology and Molecular Biology Northeast Biotechnology NetworkState University of CearáFortalezaBrazil Faculty of Veterinary Medicine State University of CearáFortalezaBrazil

Objective:To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum,and a purified ***:Mice were subjected to the following treatments:(1)purified recombinant K39(rK39)protein at a 20μg dose with complete Freund’s adjuvant;(2)Inactivated Escherichia coli(BL21 DE3)carrying the K39 protein at an equivalent total protein content of 200μg;(3)Inactivated bacteria lacking the K39 protein;(4)non-immunized control *** monitoring was *** groups were challenged by intraperitoneal injection of 10^(7) Leishmania infantum *** euthanasia,the liver and spleen were collected to analyze the levels of TnF,IFn-γ,il-12,il-4,and ***:Mice immunized with purified rK39 or the inactivated bacterial vector carrying the K39 antigen of Leishmania infantum showed a long-lasting immune response with high levels of polyclonal antibodies specifically recognizing the recombinant *** IgG1 subclass was the predominant immunoglobulin;however,the induction of IgG2a and the profile of cytokines produced were indicative of the induction of a mixed-type ***:The inactivated bacterial vector carrying the K39 antigen,as well as the purified antigen can induce a long-lasting immune response in immunized mice,predominantly favouring a Th2 profile response.

关键词： Visceral leishmaniasis K39 Inactivated bacterial vector Vaccine Immune response Th1 Th2 Leishmania infantum

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Realizing High Thermoelectric performance in n-Type Se-Free Bi2Te3 Materials by Spontaneous Incorporation of FeTe2 nanoinclusions

引用

Energy & Environmental Materials 2024年第4期7卷 344-354页

作者： Jamil Ur Rahman Woo Hyun nam Yong-Jae Jung Jong Ho Won Jong-Min Oh nguyen Van Du Gul Rahman Víctor M.García-Suárez Ran He Kornelius nielsch Jung Young Cho Won-Seon Seo Jong Wook Roh Sang-il Kim Soonil Lee Kyu Hyoung Lee Hyun Sik Kim Weon Ho Shin Leibniz Institute for Solid State and Materials Research Advanced Materials Convergence R&D Division Korea Institute of Ceramic Engineering & Technology Department of Electronic Materials Engineering Kwangwoon University Department of Energy Engineering Dankook University Faculty of Fundamental Science Phenikaa University Department of physics Quaid-i-Azam University Departamento de Física Universidad de Oviedo nanomaterials and nanotechnology Research Center-CInn Department of Materials Science and Engineering Yonsei University School of nano & Materials Science and Engineering Kyungpook National University Department of Materials Science and Engineering University of Seoul School of Materials Science and Engineering Changwon National University

Bi2Te3-based materials have drawn much attention from the thermoelectric community due to their excellent thermoelectric performance near room ***,the stability of existing n-type Bi2（Te,Se）3materials is still low due to the evaporation energy of Se (37.70 kJ mol-1) being much lower than that of Te (52.55 kJ mol-1).The evaporated Se from the material causes problems in interconnects of the module while degrading the efficiency.

关键词： Bi2Te3 energy harvesting FeTe2 nanoinclusion n-type materials thermoelectric

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Isochrone Fitting of Galactic Globular Clusters—Ⅵ.High-latitude Clusters nGC 5024 (M53),nGC 5053,nGC 5272 (M3),nGC 5466,and nGC7099 (M30)

引用

Research in Astronomy and Astrophysics 2024年第6期24卷 170-190页

作者： G.A.Gontcharov S.S.Savchenko A.A.Marchuk C.J.Bonatto O.S.Ryutina M.Yu.Khovritchev V.B.il'in A.V.Mosenkov D.M.poliakov A.A.Smirnov Central(pulkovo)Astronomical Observatory Russian Academy of SciencesPulkovskoye chaussee 65/1St.Petersburg 196140Russia Saint petersburg State University Universitetskij pr.28St.Petersburg 198504Russia Special Astrophysical Observatory Russian Academy of Sciences369167 Nizhnij ArkhyzRussia Departamento de Astronomia Instituto de FísicaUFRGSAv.Bento Gonçalves9500Porto AlegreRSBrazil Saint petersburg University of Aerospace Instrumentation Bol.Morskaya ul.67ASt.Petersburg 190000Russia Department of physics and Astronomy Brigham Young UniversityN283 ESCProvoUT 84602USA

We fit various color–magnitude diagrams(CMDs) of the high-latitude Galactic globular clusters nGC 5024(M53),nGC 5053,nGC 5272(M3),nGC 5466,and nGC 7099(M30) by isochrones from the Dartmouth Stellar Evolution Database and Bag of Stellar Tracks and Isochrones for α–enrichment [α/Fe] = +*** the CMDs,we use data sets from Hubble Space Telescope,Gaia,and other sources utilizing,at least,25 photometric filters for each *** obtain the following characteristics with their statistical uncertainties for nGC 5024,nGC 5053,nGC 5272,nGC 5466,and nGC 7099,respectively:metallicities [Fe/H] =-1.93 ± 0.02,-2.08 ± 0.03,-1.60 ± 0.02,-1.95 ± 0.02,and-2.07 ± 0.04 dex with their systematic uncertainty 0.1 dex;ages 13.00 ± 0.11,12.70 ± 0.11,11.63 ± 0.07,12.15 ± 0.11,and 12.80 ± 0.17 Gyr with their systematic uncertainty 0.8 Gyr;distances(systematic uncertainty added) 18.22 ± 0.06 ± 0.60,16.99 ± 0.06 ± 0.56,10.08 ± 0.04 ± 0.33,15.59 ±0.03 ± 0.51,and 8.29 ± 0.03 ± 0.27 kpc;reddenings E(B-V) = 0.023 ± 0.004,0.017 ± 0.004,0.023 ± 0.004,0.023 ± 0.003,and 0.045 ± 0.002 mag with their systematic uncertainty 0.01 mag;extinctions AV= 0.08 ± 0.01,0.06 ± 0.01,0.08 ± 0.01,0.08 ± 0.01,and 0.16 ± 0.01 mag with their systematic uncertainty 0.03 mag,which suggest the total Galactic extinction AV= 0.08 across the whole Galactic dust to extragalactic objects at the north Galactic *** horizontal branch morphology difference of these clusters is explained by their different metallicity,age,mass-loss efficiency,and loss of low-mass members in the evolution of the core-collapse cluster nGC 7099 and loose clusters nGC 5053 and nGC 5466.

关键词： (stars:)Hertzsprung Russell and C-M diagrams (ISM:)dust extinction (Galaxy:)globular clusters:general (Galaxy:)globular clusters:individual(nGC 5024,nGC 5053,nGC 5272,nGC 5466,nGC7099)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Solar Activity and Classical physics

引用

Chinese Journal of Astronomy and Astrophysics 2001年第2期1卷 99-124页

作者： E. n. parker (Department of physics, University of Chicago, Chicago, il 60637) Department of physics University of Chicago

This review of solar physics emphasizes several of the more conspicuous scientific puzzles posed by contemporary observational knowledge of the magnetic activity of the Sun. The puzzles emphasize how much classical physics we have yet to learn from the Sun. The physics of solar activity is based on the principles of newton, Maxwell, Lorentz, Boltzmann, et. al., along with the principles of radiative transfer. In the large, these principles are expressed by magnetohydro dynamics. A brief derivation of the magnetohydrodynamic induction and moment um equations is provided, with a discussion of popular misconceptions.

关键词： Sun: activety - Magnetohydro dynamics - radiative transfer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dual Zariski Spaces of Modules

引用

Algebra Colloquium 2023年第4期30卷 569-584页

作者： SeçilÇeken Department of Mathematics Trakya UniversityEdirneTurkey

Let R be a commutative ring with identity,M be an R-module,L(M)denote the set of all submodules of M and g■(M)\{OM}.For any submodule n of M,we set gV^(d)(n)={K∈g:K■n}and gζ^(d)(M)=(GV^(d)(n):n■L(M)).Consider χ■L(R)\{R},where L(R)is the set of all ideals of *** set χV(I)=(J∈x:I■J)and χζ(R)={xV(I):I■L(R)}for any ideal I of *** this paper,we investigate when,for arbitrary χ and g as above,χζ(R)and gζ^(d)(M)form a topology and a semimodule,*** investigate the structure of gζ^(d)(M)in the case that it is a semimodule.

关键词： dual Zariski semimodule χ-Zariski semiring ·-coprime submodule subtractive subspace

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of pacific Decadal Oscillation on Frequency Asymmetry of El nio and La nia Events

引用

Advances in Atmospheric Sciences 2018年第5期35卷 493-494页

作者： Soon-il An Department of Atmospheric Sciences Yonsei University Seou103722 Korea

El nio-Southern Oscillation（EnSO）is an abnormal sea surface warming or cooling phenomenon over the tropical pacific,which also has severe global impact.

关键词： El o and La ni a Events La

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

periodontal disease:A silent factor in the development and progression of diabetic retinopathy

引用

World Journal of Diabetes 2024年第8期15卷 1672-1676页

作者： Sarah Monserrat LomelíMartínez Irán Cortés Trujillo Melissa Martínez nieto Ana Esther Mercado González Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810Mexico Master of public Health Department of Wellbeing and SustainableCentro Universitario del NorteUniversidad de GuadalajaraColotlán 46200Mexico periodontics program Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico Antiguo Hospital Civil de Guadalajara“Fray Antonio Alcalde” Guadalajara 44280Mexico

The global increase in the prevalence of type 2 diabetes mellitus(T2DM)and its complications presents significant challenges to public ***,periodontal disease(pD)was recognized as a factor that is likely to influence the progression of T2DM and its complications due to its potential to exacerbate systemic inflammation and oxidative *** this editorial,we comment on the article published by Thazhe poyil et al in the very recent issue of the World Journal of Diabetes in 2024,which investigated the correlation between pD and diabetic retinopathy(DR)in T2DM patients,with emphasis on the association between periodontal swollen surface area,glycated hemoglobin(HbA1c),interleukin-6(il-6),and lipoprotein(a).The findings by Thazhe poyil et al are significant as they demonstrate a strong link between pD and DR in T2DM *** correlation highlights the importance of addressing periodontal health in diabetes management to potentially reduce the risk and severity of DR,a complication of *** integration of periodontal evaluation and treatment into diabetes care protocols may lead to improved glycemic control and better overall outcomes for T2DM patients.A few studies have established an interconnection between pD and diabetic complication,specifically DR,in T2DM patients,which we aim to highlight in this *** was placed on the different mechanisms that suggest a bidirectional relationship between pD and T2DM,where the presence of periodontal inflammation negatively influenced glycemic control and contributed to the development and progression of DR through shared inflammatory and vascular *** article highlights the importance of collaboration amongst diabetes specialists,ophthalmologists,periodontists,and public health professionals to advance the prevention,early detection,and treatment of pD and *** will improve the health and quality of life of T2DM ***,the editorial highlights the need for further re

关键词： Type 2 diabetes mellitus periodontal disease periodontitis Diabetic retinopathy Editorial

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

nomogram using F-18 fluorodeoxyglucose positron emission tomography/computed tomography for preoperative prediction of lymph node metastasis in gastric cancer

引用

World Journal of Gastrointestinal Oncology 2020年第4期12卷 447-456页

作者： Bong-il Song Department of nuclear Medicine Keimyung University Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea

BACKGROUnD Lymph node(Ln)metastasis is an important prognostic factor in patients with gastric cancer(GC).However,the evaluation of Ln metastasis status in the preoperative setting is not ***,precise preoperative prediction of Ln metastasis status is crucial for optimal treatment in patients with *** To develop a preoperative nomogram for Ln metastasis using F-18 fluorodeoxyglucose(F-18 FDG)positron emission tomography/computed tomography(pET/CT)and preoperative laboratory test findings in *** In this study,the data of 566 GC patients who underwent preoperative F-18 FDG pET/CT and subsequent surgical resection were *** Ln metastasis prediction model was developed in the training cohort and validated in the internal validation *** preoperative laboratory tests,including albumin and carbohydrate antigen(CA)19-9 were performed in all *** and multivariable logistic regression was performed to validate the preoperative predictive indicators for Ln *** Of the 566 patients,232(41%)had confirmed histopathologic Ln *** logistic regression revealed that the tumor location,blood hemoglobin,serum albumin levels,neutrophil to lymphocyte ratio,platelet to lymphocyte ratio,CA 19-9,maximum standardized uptake value(SUVmax)of the primary tumor(T_SUVmax),and SUVmax of Ln(n_SUVmax)were significantly associated with Ln *** multivariate analysis,T_SUVmax(OR=1.08;95%CI:1.02–1.15;p=0.011)and n_SUVmax(OR=1.49;95%CI:1.19–1.97;p=0.002)were found to be significant predictive factors for *** Ln metastasis prediction model using T_SUVmax,n_SUVmax,serum albumin,and CA 19-9 yielded an area under the curve(AUC)of 0.733(95%CI:0.683–0.784,p=0.025)in the training cohort and AUC of 0.756(95%CI:0.678–0.833,pn the test *** T_SUVmax and n_SUVmax measured by preoperative F-18 FDG pET/CT are independent predictive factors for Ln metastasis in GC.

关键词： Gastric cancer Lymph node metastasis positron emission tomography/computed tomography Fluorodeoxyglucose prognostication Standardized uptake value

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cognitive function among military veterans with STEM occupations

引用

Military Medical Research 2024年第2期11卷 308-310页

作者： Justin T.McDaniel Kevin n.Hascup Erin R.Hascup Ugochukwu G.Ezigbo Amanda M.Weidhuner Harvey Henson David L.Albright Dale and Deborah Smith Center for Alzheimer's Research and trEatment(CARE) Southern Illinois University School of MedicineSpringfieldIL 62794USA STEM Education Research Center Southern Illinois UniversityCarbondaleIL 62901USA Department of political Science The University of AlabamaTuscaloosaAL 35487USA

Dear Editor,There is limited research on the relationship between science,technology,engineering,and mathematics(STEM)occupational history and cognitive function in later life,especially among military veterans,who may be at greater risk for later-life cognitive *** study examines a nationally representative sample of military veterans to address this gap in knowledge.

关键词： Alzheimer's disease Veterans Science technology engineering and mathematics(STEM) Animal fluency test Dementia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：