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paraparesis induced by extramedullary haematopoiesis

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World Journal of Radiology 2011年第3期3卷 82-84页

作者： paolo Savini Arianna Lanzi Giorgio Marano Chiara Carli Moretti Giovanni poletti Giuseppe Musardo Francesco Giuseppe Foschi Giuseppe Francesco Stefanini Department of Internal Medicine Faenza Hospital Department of Radiology Faenza Hospitalviale Stradone 948018 FaenzaItaly Department of pathology Ravenna Hospitalviale Randi 548121 RavennaItaly

We describe a case of worsening paraparesis induced by spinal cord compression at T6-T7 levels associated with compensatory extramedullary haematopoiesis from a compound heterozygote for haemoglobin E and for β-*** e... 详细信息

关键词： Extramedullary hematopoiesis Thalassemia Anemia Spinal cord compression Laminectomy

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木偶剧团的奇遇

木偶剧团的奇遇

作者： S.·波莱蒂(S. poletti)

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木偶剧团的奇遇

木偶剧团的奇遇

急性阑尾炎:为减少对标准CT的需求预评价一种融合超声和低剂量CT的诊断方式

1985年

作者：（阿根廷）波莱蒂（poletti S.）仇新年译

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国际医学放射学杂志 2012年第1期 99-100页

作者： p.A.poletti A.platon T.De perrot F.Sarasin E.Andereggen O.Rutschmann 刘靖 Department of Radiology University Hospital of Geneva4 rue Gabrielle Perret-Gentil1211 Genève-14Switzerland

目的为了减少对常规CT的需求,应用一种融合超声和口服对比剂但未增强的低剂量CT(LDCT)的方法评价急性阑尾炎。方法步骤1:对怀疑急性阑尾炎体质量指数(BMI)在18.5到30间连续的183例成人病人(女111例,男

关键词：阑尾炎 CT 超声检查辐射剂量急诊医学

Hepatocarcinoma with metastasis to the anterior mediastinum

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Hepatoma Research 2016年第1期2卷 293-296页

作者： Rogerio Camargo pinheiro Alves Lorena Sagrilo Auer Lisa Rodrigues da Cunha Saud Raquel Coris Arrelaro Aline Carboni Casado Bruno Gustavo Ferreira Denis Szjenfeld paula Bechara poletti Department of Hepatology Instituto de Assistencia Medica ao Servidor Publico Estadual04028-000 Sao PauloBrazil Department of Gastroenterology Instituto de Assistencia Medica ao Servidor Publico Estadual04028-000 Sao PauloBrazil Department of Radiology Instituto de Assistencia Medica ao Servidor Publico Estadual04028-000 Sao PauloBrazil

Liver malignancies are the sixth leading cause of cancer worldwide,whereas hepatocellular carcinoma(HCC)is the most frequent histological type of liver *** metastasis,which rarely involves the mediastinum,is associated with poor *** 80-year-old male presenting with mild diffuse abdominal pain for 4 months,associated with hyporexia,increased abdominal volume,dry cough,and loss of 4 kg in 1 month,sought medical assistance due to hemoptysis and chest *** study revealed HCC with mediastinal metastasis,after which sorafenib therapy was *** progressed to death 4 months after the start of the treatment.

关键词： Hepatocellular carcinoma mediastinal metastasis sorafenib computed tomography

Endoscopic resection of non-ampullary duodenal adenomas: Is cold snaring the promised land?

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World Journal of Gastrointestinal Endoscopy 2023年第4期15卷 248-258页

作者： Ludovico Alfarone Marco Spadaccini Gianluca Franchellucci Kareem Khalaf Davide Massimi Alessandro De Marco Silvia Ferretti Valeria poletti Antonio Facciorusso Roberta Maselli Alessandro Fugazza Matteo Colombo Antonio Capogreco Silvia Carrara Cesare Hassan Alessandro Repici Department of Biomedical Sciences Humanitas UniversityRozzano 20089Italy Department of Gastroenterology Division of Gastroenterology and Digestive EndoscopyHumanitas Research HospitalIRCCSRozzano 20089MilanItaly Division of Gastroenterology St.Michael's HospitalUniversity of TorontoToronto M5B 1W8Canada Gastroenterology Unit Department of Medical SciencesUniversity of FoggiaFoggia 71100Italy

Due to the high risk of morbidity and mortality associated with surgical resection in this tract,endoscopic resection(ER)has taken the place of surgical resection as the first line treatment for non-ampullary duodenal ***,due to the anatomical characteristics of this area,which enhance the risk of post-ER problems,ER in the duodenum is particularly *** to a lack of data,no ER technique for superficial non-ampullary duodenal epithelial tumours(SNADETs)has yet been backed by strong,high-quality evidence;yet,traditional hot snare-based techniques are still regarded as the standard *** having a favourable efficiency profile,adverse events during duodenal hot snare polypectomy(HSp)and hot endoscopic mucosal resection,such as delayed bleeding and perforation,have been reported to be *** events are primarily caused by electrocautery-induced ***,ER techniques with a better safety profile are needed to overcome these *** snare polypectomy,which has already been shown as a safer,equally effective pro-cedure compared to HSp for treatment of small colorectal polyps,is being increasingly evaluated as a potential therapeutic option for non-ampullary duodenal *** aim of this review is to report and discuss the early outcomes of the first experiences with cold snaring for SNADETs.

关键词： Non-ampullary duodenal adenomas Endoscopic resection Cold snare polypectomy Hot snare polypectomy Safety Efficacy

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秘鲁人面部形态特征的全基因组关联分析

基因组学与应用生物学 2021年第7期40卷 2810-2818页

作者：宋春波 Macarena Fuentes-Guajardo Kaustubh Adhikari 孙畅张曼菲李晴杨光睿 Rolando Gonzalez-José Lavinia Schüler-Faccini Maria-Cátira Bortolini Victor Acuña-Alonzo Samuel Canizales-Quinteros Carla Gallo Giovanni poletti Gabriel Bedoya Francisco Rothhammer Andrés Ruiz-Linares 复旦大学生命科学学院现代人类学教育部重点实验室上海200438

人类面部形态由神经外胚层发育而来,是区别个体的最显著特征之一。研究人面部特征的遗传机制可为生物医学、司法鉴定等应用领域提供依据。虽然目前已经在正常人群和患病人群中发现了一些与面部特征相关的基因,但是还有许多面部特征的基... 详细信息

人类面部形态由神经外胚层发育而来,是区别个体的最显著特征之一。研究人面部特征的遗传机制可为生物医学、司法鉴定等应用领域提供依据。虽然目前已经在正常人群和患病人群中发现了一些与面部特征相关的基因,但是还有许多面部特征的基因有待发现。本研究基于拉美人群进化和多样性研究联合会(consortium for the analysis of the diversity and evolution of Latin America,CANDELA)队列中的1140个秘鲁健康人群,通过标定其面部的47个特征点来计算中部和下部脸部面积,并计算47个特征点之间的欧式距离,以其结果作为表型;与约七十万个单核苷酸多态性(single nucleotide polymorphisms,SNps)的全基因组分型数据进行全基因组关联分析(genome-wide association study,GWAS),并在CANDELA队列中的384个巴西和智利的独立健康人群中进行结果验证。本研究用一个加性遗传模型来进行线性回归关联检验,其中因变量为表型的数量性状,协变量为年龄、性别、身体质量指数(body mass index,BMI)及基因组群体分层分析中的前5个主成分(principal components,pCs)。研究结果表明,位于LD基因区(EDAR,LIMS1,RANBp2,SULT1C4,CCDC138,GCC2)的17个单核苷酸多态性与7个数量表型有很强的相关性;其中EDAR作为影响头面发育的一因多效性基因,在本研究中影响中部颅面形态。

关键词：面部形态特征全基因组关联分析加性遗传模型 EDAR LIMS1

Electromagnetic Stimulation Combined with Aloe vera Increases Collagen Reorganization in Burn Repair

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Journal of pharmacy and pharmacology 2018年第7期6卷 633-646页

作者： Sofia poletti Leticia D. Lucke Fernanda O Bortolazzo Renata M. Acunha Marcos G. Mattos Femanda OG. Gaspi Thiago A. M. Andrade Maria Esmeria C. Amaral Andrea A .Aro Edson R pimentel Marcelo AM. Esquisatto Fernanda A. S. Mendonga Glaucia M. T. Santos Graduate program in Biomedical Sciences of the Herminio Ometto University Center UIVIARARAS Araras Sao Paulo13607-339 Brazil Department of Structural and Functional Biology Institute of Biology University of Campinas-UNICAMP Campinas Sao Paulo13083-970 Brazil

Objectives： Burns are shown as a clinical problem for their severity and multiple complications due to the time required to heal. Therapies that improve their healing are of great importance, especially for being minimally invasive, of low cost and best performance, all related to the speed and quality of healing. This study investigated the effects of the magnetic electro stimulator Haihuá CD9 isolated or in association with Aloe vera in rats skin burns. Methods： Experimental groups （n = 30/group） were：（C） Carbopol gel; （F） A. vera/Carbopol gel; （H） Haihuá＋Carbopol gel; （H＋F） Haihuá＋A. vera/Carbopol gel. Samples were collected on the 7th, 14th, and 21st experimental days for structural and morphometric analysis, hydroxyproline and glycosaminoglycans quantification, zymography for MMp-2 and MMp-9 and Western Blotting for TGF-β1, VEGF, Collagen I and III. Key findings： The expression of TGF-β1 in H＋F was increased on the 7th day and of MMp-9 on the 7th and 14th days. The expression of VEGF increased in the first experimental periods and decreased in the last for the treated groups. There was an increase in the fibroblasts and birefringent collagen fibers in groups treated with Haihuá isolated or in association with A. vera in all periods. The quantification of collagen I increased, while collagen III decreased in H＋F. The higher amount of GAGs and MMp-2 active isoform was detected in H and H＋F during all periods. Conclusions： Considering the results of the present study, electromagnetic stimulation in association with the A. vera extract promoted an increase in the number of fibroblasts, GAGs content, MMp-2 activity, the deposition and organization of collagen fibers, favoring the repair of injuries to second degree burns, and may also present therapeutic potential in this injury type.

关键词： Burns repair herbal medicine electromagnetic stimulation rats