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An Outbreak of Serogroup y Meningococcal Meningitis in a private Secondary Vocational School-Guangzhou City,Guangdong province,China,2023

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China CDC weekly 2024年第12期6卷 242-246,I0005页

作者： Xiang zeng Qing He yilan Li yong zhou Xiaoping Shao pei Hu Jian Liang yudan Song Chao Ma Lijie zhang Limei Sun Lei Luo Chinese Field Epidemiology Training program Chinese Center for Disease Control and PreventionBeijingChina zhuhai Center for Disease Control and prevention Zhuhai CityGuangdong ProvinceChina Guangdong Center for Disease Control and prevention Guangzhou CityGuangdong ProvinceChina Guangzhou Center for Disease Control and prevention Guangzhou CityGuangdong ProvinceChina Institute of public Health Guangzhou Medical University&Guangzhou Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina Department of the National Immunization programme Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?The inclusion of meningococcal vaccines in the National Immunization program(NIp)over several years has significantly reduced the incidence of meningococcal meningitis in China to historic ***,there has been a diversification of meningococcal serogroups,leading to a shift in dominant serogroups in China from serogroup A to serogroups C and B,accompanied by a rise in reports of serogroups y and *** is added by this report?An outbreak of serogroup y Neisseria meningitidis(Nm)in a secondary vocational school involved a single confirmed severe case and 24 individuals with laboratory-confirmed Nm *** investigation revealed that the outbreak was localized to the classroom of the confirmed *** close contact within a confined space was identified as a significant risk factor for Nm *** genotype sequence identified was type 1655(ST-1655),which is categorized under clonal complex 23(CC-23)and bears resemblance to 8 previously confirmed cases of serogroup y meningococcal meningitis within Guangdong *** suggests that serogroup y infections continue to sporadically emerge and have become prevalent *** are the implications for public health practice?This outbreak underscores the critical need to enhance surveillance of meningococcal serogroups and population carrier,and advocate for vaccination with Meny-containing vaccines.

关键词： break Secondary Guangdong

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Endoscopic features and treatments of gastric cystica profunda

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World Journal of Gastroenterology 2024年第7期30卷 673-684页

作者： zi-Han Geng yan zhu pei-yao Fu yi-Fan Qu Wei-Feng Chen Xia yang ping-Hong zhou Quan-Lin Li Endoscopy Center and Endoscopy Research Institute Zhongshan HospitalFudan UniversityShanghai 200032China

BACKGROUND Gastric cystica profunda(GCp)represents a rare condition characterized by cystic dilation of gastric glands within the mucosal and/or submucosal *** is often linked to,or may progress into,early gastric cancer(EGC).AIM To provide a comprehensive evaluation of the endoscopic features of GCp while assessing the efficacy of endoscopic treatment,thereby offering guidance for diagnosis and *** This retrospective study involved 104 patients with GCp who underwent endoscopic *** demographic and clinical data,regular patient followups were conducted to assess local *** Among the 104 patients diagnosed with GCp who underwent endoscopic resection,12.5%had a history of previous gastric *** primary site predominantly affected was the cardia(38.5%,n=40).GCp commonly exhibited intraluminal growth(99%),regular presentation(74.0%),and ulcerative mucosa(61.5%).The leading endoscopic feature was the mucosal lesion type(59.6%,n=62).The average maximum diameter was 20.9±15.3 mm,with mucosal involvement in 60.6%(n=63).procedures lasted 73.9±57.5 min,achieving complete resection in 91.3%(n=95).Recurrence(4.8%)was managed via either surgical intervention(n=1)or through endoscopic resection(n=4).Final pathology confirmed that 59.6%of GCp cases were associated with *** analysis indicated that elderly males were more susceptible to GCp associated with ***,multivariate analysis identified lesion morphology and endoscopic features as significant risk *** analysis demonstrated no statistically significant difference in recurrence between GCp with and without EGC(p=0.72).CONCLUSION The findings suggested that endoscopic resection might serve as an effective and minimally invasive treatment for GCp with or without EGC.

关键词： Gastric cystica profunda Early gastric cancer Endoscopic features Endoscopic resection Endoscopy

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由超拍电子伏特加速器产生的超高能伽马射线气泡

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Science Bulletin 2024年第4期69卷 449-457页

作者： LHAASO Collaboration zhen Cao Chuandong Gao Cong Li Ruo-yu Liu Ruizhi yang 不详 Key Laboratory of particle Astrophyics&Experimental physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China University of Science and Technology of China Hefei 230026China

We report the detection of aγ-ray bubble spanning at least 100deg2 in ultra-high energy(UHE)up to a few peV in the direction of the star-forming region Cygnus X,implying the presence super peVatron(s)accelerating protons to at least 10 peV.A log-parabola form with the photon indexΓ(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is found fitting the gamma-ray energy spectrum of the bubble *** sources,“hot spots”correlated with very massive molecular clouds,and a quasi-spherical amorphousγ-ray emitter with a sharp central brightening are observed in the *** the core of~0.5°,spatially associating with a region containing massive OB association(Cygnus OB2)and a microquasar(Cygnus X-3),as well as previously reported multi-TeV sources,an enhanced concentration of UHEγ-rays is observed with 2 photons at energies above 1 *** general feature of the bubble,the morphology,and the energy spectrum,are reasonably reproduced by the assumption of a particle accelerator in the core,continuously injecting protons into the ambient medium.

关键词： Cosmic rays γ-rays Interstellar medium Star cluster

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Distributed fixed-time observers for linear time-invariant systems

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Kongzhi yu Juece/Control and Decision 2024年第11期39卷 3664-3672页

作者： zhang T. Wu H.-y. zhu z.-H. zheng X.-J. Guan z.-H. Engineering Research Center for Metallurgical Automation and Measurement Technology of Ministry of Education Wuhan University of Science and Technology Wuhan 430081 China Institute of Robotics and Intelligent Systems Wuhan University of Science and Technology Wuhan 430081 China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan 430074 China

A class of distributed fixed-time convergent observers is designed based on the bi-limit weighted homogeneous approximation theory and observability decomposition for the distributed state estimation of linear time-invariant systems. Firstly, for a single-input-single-output integrating chain system, a centralized fixed-time observer is designed for the system using bi-limit weighted homogeneous estimation. Then, the linear time-invariant system is decomposed into observable and unobservable subsystems based on the observability decomposition. Each agent in the sensor network reconstructs local observable sub-states in a fixed time based on the centralized observer by using only the system output measurements, and then state information between the agents is used to construct a consistent algorithm to estimate the local unobservable sub-states in a fixed time, thus realizing state omniscience in a fixed time. Unlike previous works, this paper does not need to construct a specific Lyapunov function to give an expression for the convergence time. Finally, the effectiveness of the designed observer is verified by simulations. © 2024 Northeast University. All rights reserved.

关键词： distributed estimation fixed-time observer linear systems observability decomposition sensor networks weighted homogeneity

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Structural design of mid-infrared waveguide detectors based on InAs/GaAsSb superlattice

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红外与毫米波学报 2024年第4期43卷 457-463页

作者： pei Jin-Di CHAI Xu-Liang WANG yu-peng zHOU yi School of physics and Optoelectronic Engineering Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Key Laboratory of Infrared Imaging Materials and Detectors Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083China

In the realm of near-infrared spectroscopy,the detection of molecules has been achieved using on-chip waveguides and *** the mid-infrared band,the integration and sensitivity of chemical sensing chips are often constrained by the reliance on off-chip light sources and *** this study,we demonstrate an InAs/GaAsSb superlattice mid-infrared waveguide integrated *** GaAsSb waveguide layer and the InAs/GaAsSb superlattice absorbing layer are connected through evanescent coupling,facilitating efficient and highquality detection of mid-infrared light with minimal *** conducted a simulation to analyze the photoelectric characteristics of the ***,we investigated the factors that affect the integration of the InAs/GaAs⁃Sb superlattice photodetector and the GaAsSb *** thicknesses and lengths for the absorption lay⁃er are *** the absorption layer has a thickness of 0.3μm and a length of 50μm,the noise equiva⁃lent power reaches its minimum value,and the quantum efficiency can achieve a value of 68.9%.The utilization of waveguide detectors constructed with Ⅲ-Ⅴ materials offers a more convenient means of integrating mid-infra⁃red light sources and achieving photoelectric detection chips.

关键词： InAs/GaAsSb superlattice waveguide detector evanescent coupling GaAsSb waveguide

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Overexpression of TRpV1 activates autophagy in human lens epithelial cells under hyperosmotic stress through Ca^(2+)-dependent AMpK/mTOR pathway

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 420-434页

作者： Liu-Hui Huang Jiao Lyu Sheng Chen Ting-yi Liang yu-Qing Rao ping Fei Jing Li Hai-ying Jin pei-Quan zhao Department of Ophthalmology Shanghai Xinhua Hospital Affiliated with Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Ophthalmology Shanghai Tenth People’s Hospital Affiliated with Shanghai Tongji University School of MedicineShanghai 200072China Centre for Eye Research Australia Royal Victorian Eye and Ear HospitalEast MelbourneVictoria 3002Australia Ophthalmology Department of SurgeryUniversity of MelbourneEast MelbourneVictoria 3002Australia Shenzhen Eye Hospital Shenzhen Key Laboratory of OphthalmologyAffiliated Shenzhen Eye Hospital of Jinan UniversityShenzhen 518040Guangdong ProvinceChina Department of Ophthalmology Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

●AIM:To explore whether autophagy functions as a cellular adaptation mechanism in lens epithelial cells(LECs)under hyperosmotic stress.●METHODS:LECs were treated with hyperosmotic stress at the concentration of 270,300,400,500,or 600 mOsm for 6,12,18,24h in *** chain reaction(pCR)was employed for the mRNA expression of autophagyrelated genes,while Western blotting detected the targeted protein *** transfection of stub-RFp-sens-GFpLC3 autophagy-related double fluorescence lentivirus was conducted to detect the level of autophagy *** electron microscopy was used to detect the existence of *** interfering RNA of autophagy-related gene(ATG)7,transient receptor potential vanilloid(TRpV)1 overexpression plasmid,related agonists and inhibitors were employed to their influence on autophagy related *** cytometry was employed to test the apoptosis and intracellular Ca^(2+)*** membrane potential was measured by JC-1 *** cell counting kit-8 assay was used to calculate the cellular *** wound healing assay was used to evaluate the wound closure *** 6.0 software was utilized to evaluate the data.●RESULTS:The hyperosmotic stress activated autophagy in a pressure-and time-dependent manner in *** 1 protein expression and conversion of LC3B II to LC3B I increased,whereas sequestosome-1(SQSTM1)protein expression *** Ca^(2+)influx was stimulated caused by hyperosmotic stress,levels of mammalian target of rapamycin(mTOR)phosphorylation decreased,and the level of AMp-activated protein kinase(AMpK)phosphorylation increased in the early *** on this evidence,autophagy activation through the Ca^(2+)-dependent AMpK/mTOR pathway might represent an adaptation process in LECs under hyperosmotic *** stress decreased cellular viability and accelerated apoptosis in LECs and cellular migration *** of autophagy by ATG7 knockdown had sim

关键词： cataract posterior capsular opacification lens epithelial cell hyperosmotic stress autophagy apoptosis transient receptor potential vanilloid 1

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Ground-state mass of ^(22)Al and test of state-of-the-art ab initio calculations

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Chinese physics C 2024年第3期48卷 72-78页

作者：孙铭泽于越王新鹏王猛李健国张玉虎 K.Blaum 陈祖毅陈瑞九邓涵宇付超义葛文文黄文嘉焦红扬李红蕙李宏福罗胤芳廖挺 yuALitvinov 司敏帅鹏史金阳王茜邢元明徐星徐瑚珊许甫荣袁琪 T.yamaguchi 颜鑫亮杨建成原有进周小红周旭张敏曾奇 CAS Key Laboratory of High precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Max-planck-Institut für Kernphysik Saupfercheckweg 169117 HeidelbergGermany GSI Helmholtzzentrum für Schwerionenforschung Planckstraße 164291 DarmstadtGermany Advanced Energy Science and Technology Guangdong Laboratory Huizhou516007China State Key Laboratory of Nuclear physics and Technology School of PhysicsPeking UniversityBeijing 100871China Department of physics Saitama UniversitySaitama 338-8570Japan School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China

The ground-state mass excess of the T_(z)=−2 drip-line nucleus ^(22)Al is measured for the first time as 18103(10)keV using the newly-developed Bρ-defined isochronous mass spectrometry method at the cooler storage ring in *** new mass excess value allowed us to determine the excitation energies of the two low-lying 1+states in ^(22)Al with significantly reduced uncertainties of 51 *** compared to the analogue states in its mirror nucleus ^(22)F,the mirror energy differences of the two 1^(+)states in the ^(22)Al-^(22)F mirror pair are determined to be−625(51)keV and−330(51)*** excitation energies and mirror energy differences are used to test the state-of-the-art ab initio valence-space in-medium similarity renormalization group calculations with four sets of interactions derived from the chiral effective field *** mechanism leading to the large mirror energy differences is investigated and attributed to the occupation of theπs_(1/2) orbital.

关键词： nuclear mass Bρ-defined IMS mirror energy difference ab initio VS-IMSRG calculations chiral interactions

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Evidence for particle acceleration approaching peV energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration zhen Cao F.Aharonian Axikegu y.X.Bai y.W.Bao D.Bastieri X.J.Bi y.J.Bi W.Bian A.V.Bukevich Q.Cao W.y.Cao zhe Cao J.Chang J.F.Chang A.M.Chen E.S.Chen H.X.Chen Liang Chen Lin Chen Long Chen M.J.Chen M.L.Chen Q.H.Chen S.Chen S.H.Chen S.z.Chen T.L.Chen y.Chen N.Cheng y.D.Cheng M.y.Cui S.W.Cui X.H.Cui y.D.Cui B.z.Dai H.L.Dai z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.Fan y.z.Fan J.Fang J.H.Fang K.Fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng y.Feng y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.L.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.Han M.Hasan H.H.He H.N.He J.y.He y.He y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.y.Huang y.Huang X.L.Ji H.y.Jia K.Jia K.Jiang X.W.Jiang z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.Li C.M.Li Cheng Li Cong Li D.Li F.Li H.B.Li H.C.Li Jian Li Jie Li K.Li S.D.Li W.L.Li W.L.Li X.R.Li Xin Li y.z.Li zhe Li zhuo Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu D.Liu D.B.Liu H.Liu H.D.Liu J.Liu J.L.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.Liu y.N.Liu Q.Luo y.Luo H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao z.Min W.Mitthumsiri H.J.Mu y.C.Nan A.Neronov L.J.Ou p.pattarakijw.nich.z.y.pei J.C.Qi M.y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song yu.V.Stenkin V.Stepanov y.Su D.X.Sun Q.N.Sun X.N.Sun z.B.Sun J.Takata p.H.T.Tam Q.W.Tang R.Tang z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.p.Wang L.y.Wang p.H.Wang R.Wang W.Wang X.G.Wang X.y.Wang y.Wang y.D.Wang y.J.Wang z.H.Wang z.X.Wang zhen Wang zheng Wang D.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu y.S.Wu S.Q.Xi J.Xia G.M.Xiang D.X.Xiao G.Xiao y.L.Xin y.Xing D.R.Xiong z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.yan J.z.yan T.yan C.W.yang C.y.yang F.yang F.F.yang L.L.yang M.J.yang R.z.yang W.X.yang y.H.yao z.G.yao L.Q.yin N.yin X.H.you z.y.you y.H.yu Q.yuan H.yue H.D.zeng T.X.zeng W.zeng M.zha B.B.zhang F.zhang H.zhang 不详 Key Laboratory of particle Astrophysics&Experimental physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-planck-Institut for Nuclear physics P.O.Box 103980Heidelberg 69029Germany School of physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&School of physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312Russia Hebei Normal University Shijiazhuang 050024China University of Science and Technology of China Hefei 230026China State Key Laboratory of particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of physics and Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of physics and Astronomy(zhuhai)&School of physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China ApC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SNR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** LHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-LAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SNRs serving as CR accelerators approaching the peV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosmic rays SNR W51C Star clusters

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Efficacy and Safety of Bufei Jiedu Granules in Treating Multidrug-Resistant pulmonary Tuberculosis:A Multi-center,Double-Blinded and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第7期30卷 579-587页

作者： zHANG Shao-yan QIU Lei zHANG Shun-xian XIAO He-ping CHU Nai-hui zHANG Xia zHANG Hui-qiang zHENG pei-yong zHANG Hui-yong LU zhen-hui Institute of Respiratory Diseases Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China Clinical Research Center Shanghai University of Traditional Chinese MedicineShanghai200032China Department of Tuberculosis Shanghai Pulmonary HospitalTongji UniversityShanghai200433China Department of Tuberculosis Beijing Chest HospitalCapital Medical UniversityBeijing101100China Department of Tuberculosis the Second Hospital of NanjingNanjing210003China Department of Tuberculosis the First Hospital Affiliated to Xinxiang Medical CollegeXinxiangHenan Province453100China

Objective: To assess the efficacy and safety of Bufei Jiedu(BFJD) Granules as adjuvant therapy for patients with multidrug-resistant pulmonary tuberculosis(MDR-pTB). Methods: A large-scale, multi-center, double-blinded, and randomized controlled trial was conducted in 18 sentinel hospitals in China from December 2012 to December 2016. A total of 312 MDR-pTB patients were randomly assigned to BFJD Granules or placebo groups(1:1) using a stratified randomization method, which both received the long-course chemotherapy regimen for 18 months(6 Am-Lfx-p-z-pto, 12 Lfx-p-z-pto). Meanwhile, patients in both groups also received BFJD Granules or placebo twice a day for a total of 18 months, respectively. The primary outcome was cure rate. The secondary outcomes included time to sputum-culture conversion, changes in lung cavities and quality of life(QoL) of patients. Adverse reactions were monitored during and after the trial. Results: A total of 216 cases completed the trial, 111 in the BFJD Granules group and 105 in the placebo group. BFJD Granules, as adjuvant treatment, increased the cure rate by 13.6% at the end of treatment, compared with the placebo(58.4% vs. 44.8%, p=0.02), and accelerated the median time to sputum-culture conversion(5 months vs. 11 months). The cavity closure rate of the BFJD Granules group(50.6%, 43/85) was higher than that of the placebo group(32.1%, 26/81;p=0.02) in patients who completed the treatment. At the end of the intensive treatment, according to the 36-item Short Form, the BFJD Granules significantly improved physical functioning, general health, and vitality of patients relative to the placebo group(all pps were not significantly different;5.1%(8/156) in the BFJD Granules group and 2.6%(4/156) in the placebo group. Conclusions: Supplementing BFJD Granules with the long-course chemotherapy regimen significantly increased the cure rate and cavity closure rate, and rapidly improved QoL of pati

关键词： alternative medicine Chinese herbal formula Bufei Jiedu Granules multidrug-resistant tuberculosis long-course chemotherapy regimen randomized controlled trial

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Simultaneously detecting transversal and longitudinal displacement with the dielectric metasurface

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Chinese Optics Letters 2024年第2期22卷 109-113页

作者：张植宇匡程辉臧昊峰鲁拥华王沛 Department of Optics and Optical Engineering University of Science and Technology of ChinaHefei 230026China Advanced Laser Technology Laboratory of Anhui province Hefei 230026China

The compact,sensitive,and multidimensional displacement measurement device plays a crucial role in semiconductor manufacture and high-resolution optical *** metasurface offers a promising solution to develop high-precision displacement *** this work,we proposed and experimentally demonstrated a two-dimensional displacement(Xz)measurement device by a dielectric *** transversal and longitudinal displacements of the metasurface can be obtained by the analysis of the interference optical intensity that is generated by the deflected light beams while the metasurface is under linearly polarized *** experimentally demonstrated that displacements down to 5.4 nm along the x-axis and 0.12μm along the z-axis can be resolved with a 900μm×900μm *** work opens up new possibilities to develop a compact high-precision multidimensional displacement sensor.

关键词： metasurface transversal and longitudinal displacement measurement

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