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In-situ study of the microstructure evolution during tension of a Mg-Y-Zn-Al alloy processed by rapidly solidified ribbon consolidation technique

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Journal of Magnesium and Alloys 2024年第5期12卷 2024-2040页

作者： Jeno Gubicza Kristián Máthis péter Nagy péter Jenei Zoltán Hegedus Andrea Farkas Jozef Vesely Shin-ichi Inoue Daria Drozdenko Yoshihito Kawamura Department of Materials physics Faculty of ScienceEotvos Loránd UniversityPázmány P.sétány 1/ABudapest H-1117Hungary Department of physics of Materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116 Praha 2Czech Republic Deutsches Elektronen-Synchrotron DESY Notkestr.85Hamburg 22603Germany Magnesium Research Center Kumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan

Mg-Y-Zn-Al alloys processed by rapidly solidified ribbon consolidation(RSRC)technique exhibit an exceptional mechanical performance indicating promising application *** material has a bimodal microstructure consisting of fine recrystallized and coarse non-recrystallized grains with solute-rich stacking faults forming cluster arranged layers(CALs)and nanoplates(CANaps),or complete long period stacking ordered(LpSo)*** order to reveal the deformation mechanisms,in-situ synchrotron X-ray diffraction line profile analysis was employed for a detailed study of the dislocation arrangement created during tension in Mg-0.9%Zn-2.05%Y-0.15%Al(at%)*** uncovering the effect of the initial microstructure on the mechanical performance,additional samples were obtained by annealing of the as-consolidated specimen at 300 and 400℃ for 2 *** heat treatment at 300℃ had no significant effect on the initial microstructure,its evolution during tension and,thus,the overall deformation behavior under tensile *** the other hand,annealing at 400℃ resulted in a significant increase of the recrystallized grains fraction and a decrease of the dislocation density,leading to only minor degradation of the mechanical *** maximum dislocation density at the failure of the samples corresponding to the plastic strain of 10-25% was estimated to be about 16-20×10^(14)m^(-2).The diffraction profile analysis indicated that most dislocations formed during tension were of non-basal and pyramidal types,what was also in agreement with the Schmid factor values revealed independently from orientation *** was also shown that the dislocation-induced Taylor hardening was much lower below the plastic strain of 3% than above this value,which was explained by a model of the interaction between prismatic dislocations and CANaps/LpSo plates.

关键词： Mg-Zn-Y-Al alloy Long period stacking ordered(LpSo)phase Cluster arranged nanoplates(CANaps) Annealing Tension Dislocation density Hardening

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A new look at the first dinosaur discovered in Antarctica: reappraisal of Antarctopelta oliveroi(Ankylosauria: parankylosauria)

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Advances in polar Science 2024年

作者： Sergio SoTo ACU?A Alexander o.VARGAS Jonatan KALUZA Consejo Nacional de Investigaciones Científicas y Técnicas (CoNICET) Red paleontológica U-Chile Departamento de Biología Facultad de Ciencias Universidad de Chile Fundación de Historia Natural Félix de Azara Universidad Maimónides Escuela de Geología Facultad de Ciencias Ingeniería y Tecnología Universidad Mayor providencia

The first dinosaur discovered in the Antarctic continent was the ankylosaur Antarctopelta oliveroi in the 1980s. Nevertheless， since then several hypotheses of phylogenetical relationships have been proposed because these have been depended on how the skeletal remains have been interpreted. The main obstacle for clarifying its phylogenetic position is that many portions of the skeleton remain unknown， in addition to the presence of unknown characters in typical ankylosaurs. Considered an ankylosaurid， nodosaurid， or even a chimaera， a recent proposal based on mostly complete material of a new ankylosaur from Chilean patagonia provided support for a novel phylogenetic hypothesis: Antarctopelta and other southern ankylosaurs are an early branching clade， the parankylosauria， whose origin probably dates to the Late Jurassic. In the light of this new view， a redescription of the available skeletal remains is provided together with a new reconstruction of the first Antarctic dinosaur known to the science community.

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Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice

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Asian pacific Journal of Tropical Biomedicine 2024年第5期14卷 199-206页

作者： Lucelina S.Araújo Bruno B.Silva Eduarda N.F.N.Santos Arnaldo S.Bezerra Samuel S.Frota Assis R.Montenegro Eridan o.p.T.Florean Maurício Fvan Tilburg Maria Izabel F.Guedes Laboratory of Biotechnology and Molecular Biology Northeast Biotechnology NetworkState University of CearáFortalezaBrazil Faculty of Veterinary Medicine State University of CearáFortalezaBrazil

objective:To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum,and a purified ***:Mice were subjected to the following treatments:(1)purified recombinant K39(rK39)protein at a 20μg dose with complete Freund’s adjuvant;(2)Inactivated Escherichia coli(BL21 DE3)carrying the K39 protein at an equivalent total protein content of 200μg;(3)Inactivated bacteria lacking the K39 protein;(4)Non-immunized control *** monitoring was *** groups were challenged by intraperitoneal injection of 10^(7) Leishmania infantum *** euthanasia,the liver and spleen were collected to analyze the levels of TNF,IFN-γ,IL-12,IL-4,and ***:Mice immunized with purified rK39 or the inactivated bacterial vector carrying the K39 antigen of Leishmania infantum showed a long-lasting immune response with high levels of polyclonal antibodies specifically recognizing the recombinant *** IgG1 subclass was the predominant immunoglobulin;however,the induction of IgG2a and the profile of cytokines produced were indicative of the induction of a mixed-type ***:The inactivated bacterial vector carrying the K39 antigen,as well as the purified antigen can induce a long-lasting immune response in immunized mice,predominantly favouring a Th2 profile response.

关键词： Visceral leishmaniasis K39 Inactivated bacterial vector Vaccine Immune response Th1 Th2 Leishmania infantum

Effects of site preparation methods on soil physical properties and outplanting success of coniferous seedlings in boreal forests

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Journal of Forestry Research 2024年第2期35卷 70-80页

作者： Aleksey S.Ilintsev Elena N.Nakvasina Alexander p.Bogdanov Northern Research Institute of Forestry 13 Nikitova Str.Arkhangelsk 163062Russian Federation Department of Silviculture and Forest Management Northern(Arctic)Federal University Named After M.V.LomonosovSevernoy Dviny Emb.17Arkhangelsk 163002Russian Federation

This study assessed the effect of patch scarification and mounding on the physical properties of the root layer and the success of tree planting in various types of *** study was conducted on 12 forest sites in taiga forests of the European part of Russia.A total of 54 plots were set up to assess seedling survival;root collar diameter,height,and heigh increment were measured for 240 seedlings to assess *** the rooting layer,240 soil samples were taken to determine physical *** study showed that soil treatment methods had no effect on bulk density and total porosity in Cladina ***,reduced soil moisture was noted,particularly in mounds,resulting in increased *** Myrtillus sites,there were increased bulk density,reduced soil moisture,and total porosity in the *** treatment in polytrichum sites resulted in reduced soil moisture and increased aeration *** the Myrtillus and polytrichum sites,patch scarification had no effects on physical *** polytrichum sites,survival rates,heights,and heigh increments of bareroot Norway spruce seedlings in mounds were higher than in patches;however,the same did not apply to *** Cladina and Myrtillus sites,there was no difference in growth for bareroot and containerised seedlings with different soil *** conditions and soil types should be considered when applying different soil treatment methods to ensure high survival rates and successful seedling growth.

关键词： Boreal forests Mechanical site preparation patch scarification Mounding Soil properties Containerised seedlings Bareroot seedlings

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Endohepatology:Arrival at the frontier of interventional endosonography

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World Journal of Gastroenterology 2024年第18期30卷 2397-2401页

作者： Shane p Selvanderan Eric Lam Neal Shahidi Department of Medicine University of British ColumbiaVancouver V6Z 1Y6BCCanada

Endohepatology describes the emerging field where diagnostic and therapeutic endoscopic ultrasound(EUS)are used for the diagnosis and management of liver disease and its *** this editorial we comment on the article by Gadour et *** spectrum of EUS-guided procedures includes liver parenchymal and lesional biopsy,abscess drainage,treatment of focal liver lesions,diagnosis of portal hypertension and management of gastric *** data suggest that the application of EUS to hepatology is technically feasible and safe,heralding the arrival at a new frontier for *** data,specifically randomised trials comparing EUS to interventional radiology techniques,and continued partnership between endoscopy and hepatology are required to see this field establish itself outside expert tertiary centres.

关键词： Cancer Cirrhosis Endoscopy Endoscopic ultrasound Liver disease

performance and combustion study of a low heat rejection engine running with biogas–diethyl ether–diesel

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Waste Disposal and Sustainable Energy 2024年第1期6卷 151-162页

作者： Sanjaya K.Mishra premananda pradhan Shakti p.Jena Department of Mechanical Engineering S‘O’A Deemed to be UniversityBhubaneswar751030India

The present research focuses on addressing the faster depletion of fossil fuels and environmental pollution in addition to the energy crisis that hinders the progress of a *** the current research,waste banana leaves were considered as substrates for biogas *** is taken as the primary fuel in dual fuel(DF)operations to maximize possible diesel *** performance and combustion assessment were executed in a low heat rejection(LHR)engine using 5%diethyl ether by volume blended with diesel(5DEE)as pilot *** combustion attributes of the engine reveal that the apex of net heat release rate(NHRR)curve retarded a bit as compared to apex of base *** peak cylinder pressure was noted to be 6.19 Mpa in the LHR engine running with 5DEE+biogas at 11.7°crank angle(CA)after top dead center(aTDC)compared to 5.23 Mpa for the diesel alone operation at the same *** apex point for NHRR was observed to be 54.51 J(°)^(−1)for 5DEE+biogas in LHR engine positioned at 3.2°*** brake thermal efficiency at full engine load operation decreased by 12.7%and 5.2%for biogas substitutions of 0.8 kg h^(−1)with diesel and 5DEE,respectively,compared to the base *** smoke opacity and nitric oxide emissions were reduced during the DF run accompanied by diethyl ether as a fuel additive.

关键词： Biogas Banana leaves Coating Diesel engine Diethyl ether Exhaust emissions

Nutritional epigenetics education improves diet and attitude of parents of children with autism or attention deficit/hyperactivity disorder

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World Journal of psychiatry 2024年第1期14卷 159-178页

作者： Renee J Dufault Katherine M Adler David o Carpenter Steven G Gilbert Raquel A Crider College of Graduate Health Studies A.T.Still UniversityKirksvilleMO 63501United States Department of Research Food Ingredient and Health Research InstituteNaalehuHI 96772United States Department of Health Sciences University of New HavenWest HavenCT 06516United States Institute for Health and the Environment School of Public HealthState University of New YorkAlbanyNY 12222United States Department of Research Institute of Neurotoxicology and Neurological DisordersSeattleWA 98105United States Department of Statistics Food Ingredient and Health Research InstituteNaalehuHI 96772United States

BACKGRoUND Unhealthy maternal diet leads to heavy metal exposures from the consumption of ultra-processed foods that may impact gene behavior across generations,creating conditions for the neurodevelopmental disorders known as autism and attention deficit/hyperactivity disorder(ADHD).Children with these disorders have difficulty metabolizing and excreting heavy metals from their bloodstream,and the severity of their symptoms correlates with the heavy metal levels measured in their *** may play a key role in helping parents reduce their ultra-processed food and dietary heavy metal intake by providing access to effective nutritional epigenetics *** To test the efficacy of nutritional epigenetics instruction in reducing parental ultra-processed food *** The study utilized a semi-randomized test and control group pretest-posttest pilot study design with participants recruited from parents having a learning-disabled child with autism or ***-two parents who met the inclusion criteria were randomly selected to serve in the test(n=11)or control(n=11)*** test group participated in the six-week online nutritional epigenetics tutorial,while the control group did *** efficacy of the nutritional epigenetics instruction was determined by measuring changes in parent diet and attitude using data derived from an online diet survey administered to the participants during the pre and post intervention *** intake scores were derived for both ultra-processed and whole/organic *** sample t-tests were conducted to determine any differences in mean diet scores within each *** There was a significant difference in the diet scores of the test group between the pre-and post-intervention *** parents in the test group significantly reduced their intake of ultra-processed foods with a preintervention diet score of 70(mean=5.385,SD=2.534)and a post-intervention diet score of 113(mean=8.692,SD=1.750)and the

关键词： Epigenomics parenteral nutrition Autism Attention deficit/hyperactivity disorder Ultra-processed foods Heavy metals

Hypothalamic circuits and aging:keeping the circadian clock updated

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Neural Regeneration Research 2024年第9期19卷 1919-1928页

作者： Rosa Vázquez-Lizarraga Lucia Mendoza-Viveros Carolina Cid-Castro Sareni Ruiz-Montoya Erick Carreño-Vázquez Ricardo orozco-Solis Instituto Nacional de Medicina Genómica(INMEGEN) México CityMéxico Centro de Investigacíon sobre el Envejecimiento Centro de Investigacíon y de Estudios Avanzados(CIE-CINVESTAV)México CityMéxico Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de México UNAMMéxico CityMéxico

over the past century,age-related diseases,such as cancer,type-2 diabetes,obesity,and mental illness,have shown a significant increase,negatively impacting overall quality of *** on aged animal models have unveiled a progressive discoordination at multiple regulatory levels,including transcriptional,translational,and post-translational processes,resulting from cellular stress and circadian *** circadian clock emerges as a key regulator,sustaining physiological homeostasis and promoting healthy aging through timely molecular coordination of pivotal cellular processes,such as stem-cell function,cellular stress responses,and inter-tissue communication,which become disrupted during *** the crucial role of hypothalamic circuits in regulating organismal physiology,metabolic control,sleep homeostasis,and circadian rhythms,and their dependence on these processes,strategies aimed at enhancing hypothalamic and circadian function,including pharmacological and non-pharmacological approaches,offer systemic benefits for healthy *** brain-directed drug administration represents a promising avenue for effectively targeting specific brain regions,like the hypothalamus,while reducing side effects associated with systemic drug delivery,thereby presenting new therapeutic possibilities for diverse age-related conditions.

关键词： aging astrocytes cellular stress responses circadian clock hypothalamus intranasal drug administration metabolic control nutrient sensor SIRT1 sleep homeostasis

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Temperature Trends and Accumulation of Chill Hours, Chill Units, and Chill portions in South Carolina

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Atmospheric and Climate Sciences 2024年第2期14卷 173-190页

作者： José o. payero Edisto Research and Education Center Clemson University Blackville SC USA Department of Agricultural Sciences Clemson University Clemson SC USA

There is considerable concern about the potential impact of climate change on agriculture, such as the accumulation of chilling hours needed to break the dormancy of many perennial plants, like fruit trees. Therefore, this study aimed to determine if there had been a significant change in air temperatures and chill hours, chill units, and chill portion accumulation in South Carolina over the last two decades. Two decades of daily maximum (Tmax) and minimum (Tmin) air temperature records were obtained from weather stations in thirty-one counties in South Carolina. Hourly temperature data, reconstructed from the daily data, were used to calculate the daily and annual chill hours, chill units, and chill portions accumulation using four different chill models for each location and year. The chill models included the T(t) °C model, the 0°C °C model, the Utah model, and the Dynamic model. For each county, regression analyses were conducted to evaluate the historical trends. Despite year-to-year variability, the tendency was a statistically significant (α = 0.05) increase in air temperature, averaging 0.089°C per year for 20 out of 31 counties in South Carolina. The other 11 counties had no significant change in temperature. The average temperature increase in the 31 counties was 0.072°C per year. The temperature increase resulted in a decrease in annual chill accumulation during the fall to spring, averaging 17.7 chill hours, 8.6 chill hours, 17.0 chill units, and 0.40 chill portions per year calculated with the T(t) °C, 0°C °C, Utah, and Dynamic models, respectively. However, whether this decrease in chill values was statistically significant or not depended on the chill model used. This study did not investigate the cause of the observed historical trends in temperature and chill accumulation. Still, if the trends continue, they could significantly impact the future of the temperate fruit tree industry in the state.

关键词： Chill Hours Chill Units Chill portions Temperature Fruit Trees Climate Change Dormancy