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The off-host survival and viability of a native and non-native fish louse （Argulus, Crustacea： Branchiura）

Current Zoology 2011年第6期57卷 828-835页

作者： p.d. walker I.J. RUSSON R. dUIJF G. VAN dER VELdE S.E. WENdELAAR BONGA Radboud University of Nijmegen Institute for Water and Wetland Research Department of Animal Ecology and Ecophysiology Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands ApEM Ltd Centre for Innovation ＆ Enterprise Begbroke Science Park Sandy Lane Yarnton Oxfordshire OX5 1PF United Kingdom Netherlands Centre for Biodiversity Naturalis P.O. Box 9517 2300 RA Leiden The Netherlands

Fish ectoparasites are introduced to water bodies or aquaculture systems along with their hosts. Argulid fish lice can survive off-host for a given time, and in spite of quarantine measures might also be introduced via the transfer of water. However, they must cope with varying abiotic conditions without access to food. We investigated the effect of temperature （5 to 28℃） on the off-host survival time of Argulus japonicus, an invasive species which is apparently increasing its distribution, and compared this with the European A. foliaceus. A clear effect of temperature on the off-host survival time of all stages of both species was demonstrated. Larval and juvenile A. japonicus survived up to 9 days at 22℃ and in the case of adults up to 13 days at 15℃. By comparison, larval A. foliaceus survived up to 5 days at 15℃, adults up to 14 days at 9℃ and juveniles up to 7 days at 9℃ and 15℃. Thus, A. japonicus is more resistant to starvation at higher temperatures under controlled off-host conditions and A. foli- aceus is more resistant to starvation at lower temperatures. Infectivity of A. japonicus decreased linearly with the time spent off-host after 2 days for larvae and 4 days for adults. Temperature only had a significant effect on the infectivity of both develop- mental stages after 24 hours off-host between 13-23℃ for larvae and 13-18℃ for adults. In conclusion both species can potentially survive off-host pelods in water transports for up to 13-14 days as adults. Their survival is shorter as larvae. This study demonstrates that transportation of water has the potential to introduce Argulus species

关键词： Argulus Fish lice Survival Temperature Off-host Water transport Introductions Invasive species

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Nd-dop.d.ZnO as a multifunctional nanomaterial

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Journal of Rare Earths 2012年第8期30卷 761-768页

作者： Surender Kumar p.d. Sahare department of physics & Astrophysics University of Delhi

Chemically synthesised ZnO and Nd-dop.d.ZnO nanoparticles were investigated for structural, optical, magnetic properties along with photocatalytic activity. Transmission electron microscopy measurement was performed on the undop.d.and dop.d.ZnO nanoparticles. Compared to the undop.d.ZnO, Nd-dop.d.ZnO nanoparticles showed enhanced photoluminescent and ferromagnetic properties. The Nd- dop.d.ZnO nanoparticles also showed improved photocatalytic properties compared with the undop.d.ZnO nanoparticles. Furthermore, the effect of UV light irradiation was studied with thermoluminescence （TL） and photoluminescence （pL） measurement techniques. It was found that in case ofNd-dop.d.ZnO nanoparticles TL intensity increased while the green emission in pL spectra decreased with UV-light irradiation. This was attributed to the production of more surface defects on UV irradiation on Nd-doping.

关键词： ZnO nanoparticles Nd-doping optical properties magnetic properties photocatalytic properties rare earths

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Synthesis of accelerograms compatible with the Chinese GB 50011-2001 design spectrum via harmonic wavelets: artifi cial and historic records

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Earthquake Engineering and Engineering Vibration 2009年第2期8卷 189-206页

作者： p.d. Spanos A. Giaralis Li Jie Rice University Houston TX 77005-1827 USA department of Civil and Environmental Engineering Rice University Houston TX 77005-1827 USA Institute of Civil Engineering Tongji University Shanghai 200092 China

A versatile approach is employed to generate artificial accelerograms which satisfy the compatibility criteria prescribed by the Chinese aseismic code provisions GB 50011-2001. In particular, a frequency dependent peak factor derived by means of appropriate Monte Carlo analyses is introduced to relate the GB 50011-2001 design spectrum to a parametrically defined evolutionary power spectrum （EpS）. Special attention is given to the definition of the frequency content of the EpS in order to accommodate the mathematical form of the aforementioned design spectrum. Further, a one-to-one relationship is established between the parameter controlling the time-varying intensity of the EpS and the effective strong ground motion duration. Subsequently, an efficient auto-regressive moving-average （ARMA） filtering technique is utilized to generate ensembles of non-stationary artificial accelerograms whose average response spectrum is in a close agreement with the considered design spectrum. Furthermore, a harmonic wavelet based iterative scheme is adopted to modify these artificial signals so that a close matching of the signals＇ response spectra with the GB 50011-2001 design spectrum is achieved on an individual basis. This is also done for field recorded accelerograms pertaining to the May, 2008 Wenchuan seismic event. In the process, zero-phase high-pass filtering is performed to accomplish proper baseline correction of the acquired spectrum compatible artificial and field accelerograms. Numerical results are given in a tabulated format to exp.d.te their use in practice.

关键词： design spectrum Chinese aseismic code artificial accelerograms evolutionary power spectrum peak factor recorded accelerograms wavelets

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Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili patricia Graham Adriana Brooks Risset Silvera Alexander J.p.Goldschmidt damien d.pearse W.dalton dietrich Allan d.Levi James d.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami project to Cure paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rap.d.y progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FdA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

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MORpHOLOGY OF AMORpHOUS SILICA dURING ALUMINUM REACTIVE pENETRATION

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Acta Metallurgica Sinica(English Letters) 2000年第4期13卷 944-948页

作者： Zhou, Z. Gan, Q.S. ding, p.d. Chongqing Univ Chongqing China

The reduction of volume of silica glass during aluminum reactive penetration was observed experimentally. The liquid aluminum infiltrates easily into the cavities while the released silicon is solved in the liquid aluminum, and Al/Al2O3 composites could be obtained. The experimental results show that Al/Al2O3 composites can be transformed into Al2O3 grains by oxygen in the cavities of Al/Al2O3 composites during the longer penetration treatment. The formation of alumina is a sintering process, in which liquid aluminum, particulate alumina and oxygen play an important role. The transformtion process has shown that there is a relationship of σAl2O3-Al2O3 2O3-Al, where σAl2O3-Al2O3 is the grain boundary energy of alumina, and σAl2O3-Al is the interface energy between aluminum and alumina. The formation temperature by aluminum reactive penetration is much lower than that by sintering.

关键词： Alumina Aluminum Metallic matrix composites Morphology Silica

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process structuring of polymers by solid phase orientation processing

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Science China Chemistry 2013年第8期56卷 1017-1028页

作者： COATES p.d. CATON-ROSE p. WARd I.M. THOMpSON G. polymer Interdisciplinary Research Centre University of Bradford University of Leeds

Solid phase orientation of polymers is one of the most successful routes to enhancement of polymer *** unlocks the potential of molecular orientation for the achievement of a range of enhanced physical *** provide here an overview of techniques develop.d.in our laboratories for structuring polymers by solid phase orientation processing routes,with a particular focus on die drawing,which have allowed control of significant enhancements of a single property or combinations of properties,including Young's modulus,strength,and *** have led to notable commercial exploitations,and examples of load bearing low density materials and shape memory materials are discussed.

关键词： polymer orientation drawing strain solid

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LARGE STRAIN TORSION OF AXIALLY-CONSTRAINEd SOLId RUBBER BARS

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Acta Mechanica Sinica 1994年第2期10卷 136-149页

作者： p.d. Wu K.W. Neale E. Van der Giessen On leave from Universite de Sherbrooke Sherbrooke Quebec Canada Laboratory for Engineering Mechanics Faculty of Mechanical Engineering and Marine Technology Delft University of Technology The Netherlands

Large strain fixed-end torsion of circular solid rubber bars is studied semi-analytically. The analyses are based on various non-Gaussian network models for rubber elasticity, some of which were proposed very recently. Results are presented in terms of predicted torque vs. twist curves and axial force vs. twist curves. In some cases, the predicted stress distributions are also given. The sensitivity of the second-order axial force to the employed models is considered. The predicted results are compared with experimental results found in the literature.

关键词： rubber network model large strain torsion

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Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nadia d’Ambrosi department of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and *** the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 *** is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关键词： STAT3 dissection sclerosis

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The Chinese skeleton: insights into microstructure that help to explain the ep.d.miology of fracture

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Bone Research 2014年第2期2卷 80-92页

作者： Elaine Cong Marcella d walker New York presbyterian Hospital

Osteoporotic fractures are a major public health problem worldwide, but incidence varies greatly across racial groups and geographic regions. Recent work suggests that the incidence of osteoporotic fracture is rising among Asian populations. Studies comparing areal bone mineral density and fracture across races generally indicate lower bone mineral density in Asian individuals including the Chinese, but this does not reflect their relatively low risk of non-vertebral fractures. In contrast, the Chinese have relatively high vertebral fracture rates similar to that of Caucasians. The paradoxically low risk for some types of fractures among the Chinese despite their low areal bone mineral density has been elucidated in part by recent advances in skeletal imaging. New techniques for assessing bone quality non-invasively demonstrate that the Chinese compensate for smaller bone size by differences in hip geometry and microstructural skeletal organization. Studies evaluating factors influencing racial differences in bone remodeling, as well as bone acquisition and loss, may further elucidate racial variation in bone microstructure. Advances in understanding the microstructure of the Chinese skeleton have not only help.d.to explain the ep.d.miology of fracture in the Chinese, but may also provide insight into the ep.d.miology of fracture in other races as well.

关键词： bone insights into microstructure that help to explain the ep.d.miology of fracture The Chinese skeleton

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Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López Neurophysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

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