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Antihyperglycemic activity,antihyperlipedemic activity,haematological effects and histopathological analysis of Sapindus mukorossi Gaerten fruits in streptozotocin induced diabetic rats

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Asian pacific Journal of Tropical Medicine 2012年第7期5卷 518-522页

作者： Neeraj Verma G Amresh p K sahu Neelam Mishra Anil p Singh ch V Rao Department of pharmacology Goel Institute of Pharmacy & SciencesFaizabad Road(Near Indira Canal) Lucknow 227105Uttar PradeshIndia Department of pharmacology School of Pharmaceutical SciencesSiksha 'O' Anusandhan UniversityKalinga NagarGhatikiaBhubaneswar 751003 OrissaIndia Department of pharmacology Pharmacognosy and Ethnopharmacology DivisionNational Botanical Research Institute(Council of Scientific and Industrial Research)Rana Pratap MargP.O.Box No.436Lucknow 226001Uttar PradeshIndia

Objective:To investigate the antihyperglycemic and antihyperlipidemie properties of hydroalcoholic extract of fruits of Sapindus mukorossi Caerlen and its beneficial effect on haeniatological parameters with histopathological analysis in streptpzotocin induced diabetic ***:Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and standard drug glybenclamide(0.5 mg/kg body weight) were administered to diabetic *** of extract on hyperglycemia,hyperlipidemia and hematological parameters was studied in diabetic *** changes in diabetic rat pancreas were also observed after extract and glybenclamide ***:Daily oral administration of Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and glybenclamide for 20 days showed beneficial effects on blood glucose level(ppid *** extract has a favorable effect on the histopathological changes of the pancreas in streptozotocin induced ***: These findings reveal that the hydroalcoholic extract of Sapindus mukorossi fruits extract possesses antihyperglycemic and antihyperlipidemie *** *** extract can prevent various complications of diabetes and improve some haeniatological parameters.

关键词： Antihyperglycemic Antihyperlipidemic Streptozotocin Sapindus mukorossi

Antihyperglycemic and antihyperlipidemic activity of ethyl acetate fraction of Rhododendron arboreum Smith flowers in streptozotocin induced diabetic rats and its role in regulating carbohydrate metabolism

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Asian pacific Journal of Tropical Biomedicine 2012年第9期2卷 696-701页

作者： Neeraj Verma G Amresh pK sahu ch V Rao Anil pratap Singh Department of pharmacology Goel Institute of Pharmacy&SciencesFaizabad Road(Near Indira Canal) Department of pharmacology School of Pharmaceutical SciencesSiksha'O' Anusandhan UniversityKalinga NagarGhatikia pharmacognosy and Ethnopharmacology Division National Botanical Research Institute(Council of Scientific and Industrial Research)Rana Pratap Marg

Objective:To explore and identify the most potent antihyperglycemic fraction from the ethanol extract of Rhododendron arboreum(***)***:Normal and streptozotocin induced diabetic rats were treated with all four fractions of *** flowers for short term and with fraction 3 for long term *** completion of the treatment,a range of indicators were tested including fasting blood glucose,plasma protein,haemoglobin A1C,insulin secretion,body weight,blood lipid profile and carbohydrate metabolism regulating enzymes of ***:In short term study,the fraction 3(Active fraction)produced a significant(pptozotocin diabetic rats resulted in a significant(ppperlipidemic activity as evidenced by significant(ppcholesterol,triglycerides,low density lipoprotein cholesterol and very low density cholesterol levels coupled together with elevation of high density lipoprotein cholesterol in the diabetic ***:The active fraction of *** flowers decreases streptozotocin induced hyperglycemia by promoting insulin secretion and glycolysis and by decreasing gluconeogenesis.

关键词： Antihyperglycemic Antihyperlipidemic Ethanol Fraction Rhododendron arboreum Streptozotocin

Flower Farms Environmental performance Evaluation in Ethiopia

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Journal of Environmental & Earth Sciences 2021年第1期3卷 48-58页

作者： Tafesse Hawera Belay Tefera Omprakash sahu Department of chemical Engineering KiOT Wollo UniversityEthiopia Department of chemical and Food Engineering BiTBahir Dar UniversityEthiopia Department of chemical Engineering UIEChandigarh UniversityMohaliIndia

Cultivation of cut flowers is a new agricultural sector in Ethiopia,which currently generates a high amount of income for the country's develop*** its significant contribution to economic developments;many issues were raised from communities and environmentalists concerning its environmental *** on this issue the study assesses cradle to gate of cut flower production in the Wolmera *** main objective of the study was environmental performance evaluation of flower farms in Wolmera district,Oromia regional state,Ethiopia related to operational activities throughout entire life cycles of cut flower pro*** this study,primary and secondary data were collected using ISO 14031 standard structured with LCA tool *** were collected by inventory using an on-site data collection system from its *** on data collected GHG(CO2,N2O,ch4&NH3)emissions to the atmosphere were evaluated by using an inter-governmental panel on climatic changes(IpCC 2006)for inventory data and eutrophication&acidification estimated from data tested at laboratory ***,the study also assesses banned chemicals used in the farms through inventory data assessment,and about 156 chemicals applied in the farms were collected to screen out those banned chemicals used and the two most extremely hazardous chemicals(Impulse&Meltatix)banned by WHO identified in the *** it understood from a general assessment of all flower farms;all of them haven't EIA document established before construction in the district and production started with having less attention for EHpEA code of conducts in the flower farms which faces the environments for high impacts by emission emitted from flower farms in the district as a whole.

关键词： Resources used ISO 14031 and LCA Operational performances EpE Emission

phenol in High-mass Star-forming Regions

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Research in Astronomy and Astrophysics 2022年第6期22卷 256-268页

作者： Rana Ghosh Milan Sil Suman Kumar Mondal prasanta Gorai Dipen sahu Rahul Kumar Kushwaha Bhalamurugan Sivaraman Ankan Das Indian Centre for Space physics 43 ChalantikaGaria Station RoadKolkata 700084India S.N.Bose National Centre for Basic Sciences Salt LakeKolkata 700106India Department of Space Earth&EnvironmentChalmers University of TechnologySE-41296 GothenburgSweden Institute of Astronomy and Astrophysics Academia Sinica Taipei Taipei 10617China Atomic and Molecular physics Laboratory Institute for Nuclear Research(Atomki)Debrecen H-4026Hungary physical Research Laboratory NavrangpuraAhmedabad 380009India

phenol,which belongs to the C_(6)H_(6)O isomeric group,is the simplest molecule in the family of alcohol of the aromatic *** phenol has yet to be detected in the interstellar medium,a tentative identification was reported toward the Orion KL hot core using the IRAM-30 m line *** explore some more species of this isomeric group,we consider ten species to study the fate of their astronomical *** is noticed that phenol is the most energetically favorable isomer of this *** contrast,propargyl ether is the least favorable(having relative energy~103kcal mol^(-1)compared to phenol)species of this *** far,the studies associated with the formation of phenol are heavily concentrated on combustion ***,we suggest a few key reactions(C_(6)H_(6)+OH→C_(6)H_(5)+H_(2)O,C_(6)H_(6)+O→C_(6)H_(5)OH,C_(6)H_(6)+H→C_(6)H_(5)+H_(2),and C_(6)H_(5)+OH→C_(6)H_(5)OH+hν)for the formation of *** these pathways are included in a large gas-grain chemical network to study its formation in high mass star-forming regions and dark cloud *** is noticed that the phenyl(-C_(6)H_(5))formation by the ice-phase hydrogen abstraction reaction of benzene(i.e.,C_(6)H_(6)+OH→C_(6)H_(5)+H_(2)O if allowed at~10 K)could serve as the starting point for the formation of phenol in the gas phase by radiative association reaction C_(6)H_(5)+OH→C_(6)H_(5)OH+hν.The gasphase reaction C_(6)H_(6)+O→C_(6)H_(5)OH significantly contributes to the formation of phenol,when the ice-phase reaction C_(6)H_(6)+OH→C_(6)H_(5)+H_(2)O is not considered at low *** 4 ALMA archival data of a hot molecular core,G10.47+0.03,are *** yields an upper limit on phenol abundance of 5.19×10^(-9).Our astrochemical model delivers an upper limit on phenol abundance of~2.20×10^(-9)in the hot molecular core,whereas its production in the dark cloud is not satisfactory.

关键词： astrochemistry-ISM abundances-ISM molecules-(ISM:)evolution

Hydrothermal Growth of Zinc Oxide Nanorods and Glucose-Sensor Application

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Soft Nanoscience Letters 2013年第4期3卷 23-26页

作者： Shinji Nozaki Sachindra N. Sarangi Kazuo Uchida Surendra N. sahu Center for Nanoscience and Technology National Institute of Science & Technology Palur Hills Berhampur India. Graduate School of Informatics and Engineering The University of Electro-Communications Tokyo Japan Institute of physics Sachivalaya Marg Bhubaneswar India

High-quality zinc oxide nanorods were grown on various substrates using zinc nitrate (Zn(NO3)2) and hexamethylenetetramine ((ch2)6N4). The substrates greatly affect the hydrothermal growth of ZnO nanorods. Making the best use the substrate effect, we engineered substrates to make a single nanorod in each hole of 100 nm × 100 nm in the array of the holes on the photoresist-patterned substrate. It is also interesting to note that high-quality ZnO nanorods grown on GaN substrates by the hydrothermal growth technique have demonstrated the potential application as a glucose sensor without oxidase for the first time. The photoluminescence in the UV wavelength range was quenched by immobilizing glucose on the ZnO surface. The peak intensity decreased increased with the increased glucose concentrations. A good linearity and high sensitivity were obtained for the glucose concentrations of 0.5-30 mM in the calibration curve. The calibration curve was not influenced by the presence of bovin serum albumin (BSA), ascorbic acid (AA) and uric acid (UA), which are also included in human blood and could cause interference in estimating glucose concentrations in human blood. The pL quenching was attributed to the H2O2 molecules, which were produced by the photo-oxidation of glucose during exposure to UV light. The pL-quenching glucose sensor made of ZnO nanorods has been evaluated for the first time by estimating the glucose concentrations in the human serum samples which include those of diabetes, and a good correlation was obtained between the concentrations by the pL quenching and the clinical data provided by a local hospital.

关键词： ZnO Hydrothermal Growth Glucose Sensor photoluminescence Quenching