检索结果-南通市图书馆

Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

pOlYMER NETWORK-pOlY(ETHYlENE GlYcOl)cOMplEXES WITH SHApE MEMORY EFFEcT

在线全文

学校读者我要写书评

暂无评论

chinese Journal of polymer Science 2003年第1期21卷 29-33页

作者： Yi-ping cao c.W.yip 等 InstituteofOrganicchemistry ChineseAcademyofSciencesChengdu610041China DepartmentofAppliedBiologyandchemicalTechnology hongKongPolytechnicUniversityHungHomkowloonHongKongChina

The complexes of poly(methacrylic acid-co-methyl methacrylate) network with poly(ethylene glycol) stabilized byhydrogen bonds were prepared. By introducing the poly(ethylene glycol), a large difference in storage modulus below andabove the glass transition temperature occurred and the complexes exhibited shape memory behaviors. The morphology ofcomplexes was studied by using DSc, WAXD, and DMA. The results indicate that the fixed phase of this kind of novelshape memory materials is the network, and the reversible phase is the amorphous state of pEG:pMAA complex phase. Theshape recoverability almost reaches 100%. This type of complexes can be regarded as a novel shape memory network.

关键词： Hydrogen bonded complex Shape memory effect Storage modulus ratio

Status and prospects for symmetric organic redox flow batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： carina Hromada patrick Heimel Markus Kerbl lászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes c.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian cluster for Tissue Regeneration ViennaAustria ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University clinic of Dentistry Medical University of ViennaViennaAustria Department of plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGcs). However, the use of tNGcs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGc would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGcs and compared the various features of these improved silk^(+) tNGcs with the tubes without holes(silk^(–) tNGcs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGcs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGcs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGcs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGcs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

Better Use of Data to Define Nutrition priority and Action

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2001年第1期14卷 61-65页

作者： RAY yip Senior Adviser Health Nutrition UNICEF Area Office for China and Mongolia

Nutrition and dietary survey data has been useful in defining the magnitude of malnutrition and dietary deficit. Such information has been helpful in gaining attention to support or to do more to improve nutrition advocacy. However, there are also greater opportunities to use the common data to guide the program action. In summary, we have plenty of good nutrition and dietary information available to us in the planning and operation of nutrition intervention program. If we go beyond the use of data to justify area or subject of engagement, we can also use the same data for more efficient and more effective program without additional cost to us.

关键词： Nutrition policy Nutrition Surveys policy Making public policy Data collection Humans Nutrition Disorders public Health

RepDNet:A re-parameterization despeckling network for autonomous underwater side-scan sonar imaging with prior-knowledge customized convolution

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第5期35卷 259-274页

作者： Zhuoyi li Zhisen Wang Deshan chen Tsz leung yip Angelo p.Teixeira Department of logistics and Maritime Studies The Hong Kong Polytechnic UniversityChina State Key laboratory of Maritime Technology and Safety Wuhan University of TechnologyChina School of Transportation and logistics Engineering Wuhan University of TechnologyChina National Engineering Research center for Water Transport Safety Wuhan University of TechnologyChina centre for Marine Technology and Ocean Engineering(cENTEc) Instituto Superior TecnicoUniversidade de LisboaPortugal

Side-scan sonar(SSS)is now a prevalent instrument for large-scale seafloor topography measurements,deployable on an autonomous underwater vehicle(AUV)to execute fully automated underwater acoustic scanning imaging along a predetermined ***,SSS images often suffer from speckle noise caused by mutual interference between echoes,and limited AUV computational resources further hinder noise *** approaches for SSS image processing and speckle noise reduction rely heavily on complex network structures and fail to combine the benefits of deep learning and domain *** address the problem,Rep DNet,a novel and effective despeckling convolutional neural network is *** DNet introduces two re-parameterized blocks:the pixel Smoothing Block(pSB)and Edge Enhancement Block(EEB),preserving edge information while attenuating speckle *** training,pSB and EEB manifest as double-layered multi-branch structures,integrating first-order and secondorder derivatives and smoothing *** inference,the branches are re-parameterized into a 3×3 convolution,enabling efficient inference without sacrificing *** DNet comprises three computational operations:3×3 convolution,element-wise summation and Rectified linear Unit *** on benchmark datasets,a real SSS dataset and Data collected at lake Mulan aestablish Rep DNet as a well-balanced network,meeting the AUV computational constraints in terms of performance and latency.

关键词： Side-scan sonar Sonar image despeckling Domain knowledge Re-parameterization

3D FINITE ElEMENT ANAlYSIS OF THE DAMAGE EFFEcTS ON THE DENTAl cOMpOSITE SUBJEcT TO WATER SORpTION

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2006年第3期19卷 212-222页

作者： Tsui c.p. chow c.l. Department of Industrial and Systems Engineering The Hong Kong polytechnic University Hong Kong ChinaDepartment of Mechanical EngineeringThe University of Michigan-DearbornDearbornMichiganUSA

The damage effects of water sorption on the mechanical properties of the hydroxyapatite particle reinforced Bis-GMA/TEGDMA copolymer （HA/Bis-GMA/TEGDMA） h-ave been predicted using 3D finite cell models. The plasticizer effect on the polymer matrix was considered as a variation of its Young＇s modulus. Three different cell models were used to determine the influence of varying particle contents, interphase strength and moisture concentration on the debonding damage. The stress distribution pattern has been examined and the stress transfer mode clarified. The Young＇s modulus and fracture strength of the Bis-GMA/TEGDMA composite were also predicted using the model with and without consideration of the damage. ine Iormer results with consideration of the debonding damage are in good agreement with existing literature experimental data. The shielding effect of our proposed model and an alternative approach were discussed. The Fcc cell model has also been extended to predict the critical load for the damaged and the undamaged composite subject to the 3-point flexural test.

关键词： water sorption dental composite interphase debonding finite element method (FEM) unit cell model

pathological mechanisms and therapeutic strategies for Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第3期17卷 543-549页

作者： Yaojun Ju Kin yip Tam Faculty of Health Sciences University of MacaoAvenida de UniversidadeTaipaMacao Special Adiministrative RegionChina

Alzheimer's disease is a rather complex neurodegenerative disease,which is attributed to a combination of multiple *** the many pathological pathways,synaptic dysfunctions,such as synapses loss and deficits in synaptic plasticity,were thought to be strongly associated with cognitive *** deficiencies in various sorts of neurotransmissions are responsible for the multifarious neurodegenerative symptoms in Alzheimer's disease,for example,the cholinergic and glutamatergic deficits for cognitive decline,the excitatory and inhibitory neurotransmission dyshomeostasis for synaptic plasticity deficits and epileptiform symptoms,and the monoamine neurotransmission for neuropsychiatric *** cascade hypothesis is the most popular pathological theory to explain Alzheimer's disease pathogenesis and attracts considerable *** lines of genetic and pathological evidence support the predominant role of amyloid beta in Alzheimer's disease *** tangles assembled by microtubule-associated protein tau are other important histopathological characteristics in Alzheimer's disease *** of tau toxicity was proved to lead to neuron damage,neuroinflammation and oxidative stress in *** is the main risk factor of neurodegenerative diseases,and is associated with inflammation,oxidative stress,reduced metabolism,endocrine insufficiencies and organ *** aging related risk factors were also proved to be some of the risk factors contributing to Alzheimer's *** Alzheimer's disease drug development,many good therapeutic strategies have been investigated in clinical ***,complex mechanism of Alzheimer's disease and the interplay among different pathological factors call for the come out of allpowerful therapies with multiple curing *** review seeks to summarize some of the representative treatments targeting different pathological pathways currently under clinical ***

关键词： Alzheimer's disease pathological pathways drug development multiple pathologies

characterization of Fe_3O_4/p(St-MpEO) Amphiphilic Magnetic polymer Microspheres

在线全文

学校读者我要写书评

暂无评论

chemical Research in chinese Universities 2002年第4期18卷 458-461页

作者： cHAN AlBERT S. c. yip c. W. Open laboratory of chirotechnology and Department of Applied Biology and chemical Technology Open Laboratory of Chirotechnology and Department of Applied Biology and Chemical Technology Hong Kong Polytechnic University Hong Kong P. R. ChinaHong Kong Polytechnic University Hong Kong P. R. China

Amphiphilic magnetic microspheres consisting of styrene and poly(ethylene oxide) macromonomer(MpEO) were prepared by dispersion copolymerization in the presence of Fe_3O_4 magnetic fluid in an ethanol/water medium. The sizes of the magnetic microspheres and their distribution were characterized by means of scanning electron microscopy(SEM). The surface morphology and the average surface roughness of the microspheres were investigated by virtue of atomic force microscopy(AFM). It was found that the microspheres exhibit microscopic phase-separate and the mean square surface roughness of the microspheres increases with increasing MpEO used in the copolymerization. The amphiphilic magnetic microspheres containing 0 4-3 5 mg/g hydroxyl groups could be prepared from MpEO with different concentrations and styrene.

关键词： Amphiphilic magnetic polymer Microsphere copolymerization