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Journal of Geriatric Cardiology 2011年第4期8卷 201-206页

作者： Ernst R Schwarz Robert D Willix jr Cenegenics Education and Research Foundation Las Vegas and Heart Institute of Southern CaliforniaBeverly Hills348 S Oakhurst DrBeverly HillsCA 90212USA

Background partial androgen deficiency syndrome in the aging male is associated with signs of aging such as a development of abdominal obesity,sexual dysfunction,increase body fat,weight gain and the development of cardiac *** We assessed the outcome of a commercially available physician supervised nutrition and exercise program with concomitant testosterone replacement therapy in middle age obese men with partial androgen deficiency in order to reduce cardiac risks *** Fifty-six self referred men without diabetes mellitus,hypertension,or cardiovascular disease(ages 52.3±7.8 years)were randomly selected from a large *** weight,body fat composition,fasting glucose,hemoglobin A1c and fasting lipid levels,as well as free and total testosterone levels were *** patients were assessed and followed 6–18 months after initiation of the *** program consisted of a low glycemic load balanced nutrition diet,a recommended structured daily exercise program of 30–60 minutes,as well as once to twice weekly intramuscular testosterone injections(113.0±27.8 mg).Results At follow up,weight was reduced from 233.9±30.0 pounds(lbs)to 221.3±25.1 lbs(pppppplacement therapy in middle aged obese men with partial androgen deficiency appeared safe and might have promoted the effects of a weight reduction diet and daily exercise program as long as an adequate physician supervision and follow up was *** combination therapy significantly reduced coronary risk factors such as glucose intolerance and hyperlipidemia.

关键词： aging heart disease androgen deficiency testosterone

polymer-virus core-shell structures prepared via co-assembly and template synthesis methods

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Science China Chemistry 2010年第1期53卷 71-77页

作者： SUTHIWANGCHAROEN Nisaraporn pREVELIGE peter E.jr Department of Chemistry and Biochemistry and Nanocenter University of South CarolinaColumbiaSouth Carolina 29208USA Department of Microbiology University of Alabama at BirminghamBirminghamAL 35294USA

Bionanoparticles(BNps),consisting of virus and virus-like assemblies,have attracted much attention in the biomedical field for their applications such as imaging and targeted drug delivery,owing to their well-defined structures and well-controlled ***-based core-shell structures provide a unique system for the investigation of biological interactions such as protein-protein and protein-carbohydrate ***,it is still a challenge to prepare the BNps-based core-shell ***,we describe(i) co-assembly method and(ii) template synthesis method in the development of polymer-BNps core-shell *** two methods can be divided into three different *** system A,different polymers including poly(2-vinylpyridine)(p2Vp),poly(4-vinylpyridine)(p4Vp) and poly(ε-caprolactone)-block-poly(2-vinylpyridine)(pCL-b-p2Vp) can form a raspberry-like structure with *** system B,polystyrene(pS) spheres end capped with free amine and BNps can form a core-shell *** System C,layer-by-layer(LBL) method is used to prepare positive charged pS particles,which can be used as a template to form the core-shell structures with *** two methods may open a new way for preparing novel protein-based functional materials for potential applications in the biomedical field.

关键词： core-shell structures bionanoparticles virus polymers co-assembly template synthesis layer-by-layer

Ethanol inhibits the motility of rabbit sphincter of Oddi in vitro

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World Journal of Gastroenterology 2004年第23期10卷 3470-3474页

作者： Réka Sári Attila pálv lgyi Zoltán Rakonczay jr.Tamás Takács János Lonovics László Czakó péter Hegyi Zoltán Szilvássy First Department of Medicine Faculty of MedicineUniversity of Szeged H-6720Koranyi fasor 10Hungary Department of pharmacology Medical University of Debrecen H-4032Nagyerdei krt98Hungary

AIM:The rote of the sphincter of Oddi(SO)in ethanol (ETOH)-induced pancreatitis is *** aim was to characterise the effect of E-I-OH on basal and stimulated SO motility. METHODS:SOs removed from white rabbits were placed in an organ bath(Krebs solution,pH7.4,37℃).The effects of 2 mL/L,4 mL/L,6 mL/L and 8 mL/L of ETOH on the contractile responses of the sphincter were determined. SOs were stimulated with either 0.1 μmol/L carbachol,1 μmol/L erythromycin or 0.1 μmol/L cholecystokinin(CCK). RESULTS:ETOH at a dose of 4 mL/L significantly decreased the baseline contractile amplitude from 11.98±0.05 mN to 11.19±0.07 ***,no significant changes in the contractile frequency were ***(0.6%) significantly decreased both the baseline amplitude and the frequency compared to the control group(10.50±0.01 mN, 12.13±0.10 mN and 3.53±0.13 c/min,5.5±0.13 cycles(c)/min, respectively).Moreover,0.8% of ETOH resulted in complete relaxation of the ***(0.1 μmol/L)or erythromycin (1 μmol/L)stimulated the baseline amplitudes(by 82% and 75%,respectively)and the contractile frequencies (by 150% and 106%,respectively).In the carbachol or erythromydn-stimulated groups 2-6 mL/L of E-IOH significantly inhibited both the amplitude and the ***, a 4-5 min administration of 6 mL/L ETOH suddenly and completely relaxed the ***(0.1 μmol/L)stimulated the baseline amplitude from 12.37±0.05 mN to 27.40±1.82 mN within 1.60±0.24 *** this peak,the amplitude decreased to 17.17±0.22 mN and remained constant during the *** frequency peaked at 12.8±0.2 c/min, after which the constant frequency was 9.43±0.24 c/min throughout the rest of the *** at a dose of 4 mL/L significantly decreased the amplitude from 16.13±0.23 mN to 14.93±0.19 ***,no significant changes in the contractile frequency were *** at a dose of 6 mL/L inhibited both the amplitudes and the frequencies in the CCK-stimulated group,while 8 mL/L of E

关键词： Animals Carbachol Central Nervous System Depressants Cholecystokinin Cholinergic Agonists Erythromycin Ethanol Gastrointestinal Agents Gastrointestinal Motility In Vitro Male Rabbits Research Support, Non-U.S. Gov't Sphincter of Oddi

A pROSpECTIVE RANDOMIZED COMpAR-ATIVE STUDY BETWEEN ENDOSCOpIC CYCLOpHOTOCOAGULATION AND THE AHMED DRAINAGE IMpLANT IN RE-FRACTORY GLAUCOMA

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国际眼科杂志 2003年第1期3卷 85-86页

作者： F.E.Lima L.Magacho D.M.Carvalho M.p.Avila R.Susanna jr. Federal Uni-versity of Goias University of Sao PauloFederal Uni-versity of Goias University of Campinas BrazilFederal Uni- versity of GoiasFederal Uni- versity of GoiasUniversity of Sao Paulo

purpose: To compare endoscopic cyclophotocoagulation (ECp) and Ahmed drainage implant in the treatment of refractory glaucoma. Methods: 68 eyes with refractory glaucoma were randomized prospectively to either ECp or Ahmed tube shunt implantation, always performed by a single surgeon. Eyes that were included were pseudophakic with a history of at least one tra-beculectomy with an antimetabolite, and a visual acuity

关键词：难治性青光眼内镜睫状体光凝固艾哈默德引流植入物随机比较研究

Levels of Chemical Toxicants in Waterpipe Tobacco and Waterpipe Charcoal Solid Waste

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Journal of Environmental protection 2021年第11期12卷 913-938页

作者： Jason R. Hsieh Megan L. Mekoli Ronald L. Edwards jr. Office of Science Center for Tobacco Products U.S. Food and Drug Administration Calverton MD USA

This work provides insights on waterpipe tobacco and waterpipe charcoal as potential sources of environmental toxicants. Selected harmful and potentially harmful constituents (HpHCs) from ten U.S. commercial waterpipe tobacco filler products (before and after electric heating) and five waterpipe charcoal products (before and after burning) were investigated. The differences in quantities of HpHCs between the evaluated products appear to be affected by raw material properties and/or the manufacturing processes involved in product production. Trace metal quantities in waterpipe tobacco and charcoal products were observed after heating or burning conditions compared to unheated or unburned conditions, which could impact the environment through the generation of toxic tobacco product waste. This study demonstrates that waterpipe tobacco and waterpipe charcoal contain substantial quantities of benzo[a]pyrene (B[a]p) and trace metals (i.e., selenium, arsenic, cadmium, chromium, cobalt, lead, nickel) before use and that extensive and varied changes in trace metal quantities take place as a result of heating, and more studies are needed to estimate the magnitude of the environmental impact of waterpipe tobacco use.

关键词： Harmful and potentially Harmful Constituents Charcoal Waterpipe Metals Tobacco product Waste

The New Brazilian power Quality Standard and a Low Cost Device Meter

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Energy and power Engineering 2012年第3期4卷 144-152页

作者： Guilherme p. Colnago Jose L. F. Vieira Gilberto C. D. Sousa Jose R. Macedo jr. Electrotechnical Department Federal Institute of Espirito Santo Vitoria Brazil Department of Electrical Engineering Federal University of Espirito Santo Vitoria Brazil Department Electrical Engineering Federal University of Uberlandia Uberlandia Brazil

This paper presents an overview about the new Brazilian power Quality Standard and provides a low cost device pQ meter, developed and implemented to assist the national campaign to assess the Brazilian power quality indices, unknown until now. This work contributes with the search of a low cost devices pQ meter for a cost sensitive market, and introduces the new Brazilian power Quality Standard to the international community.

关键词： power Quality Standard power System Monitoring Brazilian Electrical System

高取向热解石墨纳米孔的制备、控制及纳米结构的模板合成

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世界科技研究与发展 2002年第6期24卷 42-49页

作者：朱英杰 Thomas p.Beebe jr. 中国科学院上海硅酸盐研究所高性能陶瓷和超微结构国家重点实验室美国Delaware大学化学与生物化学美国Delaware大学化学与生物化学系

高取向热解石墨 (HOpG)单层及多层纳米孔可作为结构模板合成金属或半导体纳米结构。本文介绍了作者最近有关用高聚焦离子束轰击和热氧化法在HOpG上制备大小、深度 (单层、多层 )、密度可控的纳米孔 ,以及控制纳米孔的形成位置制备周期... 详细信息

高取向热解石墨 (HOpG)单层及多层纳米孔可作为结构模板合成金属或半导体纳米结构。本文介绍了作者最近有关用高聚焦离子束轰击和热氧化法在HOpG上制备大小、深度 (单层、多层 )、密度可控的纳米孔 ,以及控制纳米孔的形成位置制备周期性的纳米孔有序阵列等工作。并对用HOpG纳米孔作为结构模板合成金属或半导体纳米结构及其有序阵列体系也作了介绍。

关键词：高取向热解石墨纳米孔制备纳米结构模板合成

The Science and Design of Engineering Materials (Second Edition) 2nd ed.

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Antral exfoliative cytology for the detection of Helicobacter pylori in the stomach

1999年

作者： Ashok Saxena, Stephen D. Antolovich, Thomas H. Sanders, jr., Steven B. Warner James p. Schaffer

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastroenterology 2005年第18期11卷 2784-2788页

作者： Claudio A.R. Gomes jr.Wilson R. Catapani Ana M.A.A. Mader Angelo Locatelli Claudilene B.p. Silva Jaques Waisberg Department of Gastroenterology Surgery and pathology ABC Faculty of Medicine Avenida Príncipe de Gales 821 Santo André S■o Paulo Brazil

AIM: To evaluate the efficacy of antral exfoliative cytology method in the diagnosis of Helicobacter pylori (H pylori)infection in the ***: Fifty patients were submitted to upper digestivetract endoscopy due to complaints of dyspepsia. Thematerial for exfoliative cytology was obtained by extensive brushing of the gastric antral mucosa and papanicolaou stain was used to identify the bacteria. The authors also performed gastric biopsies to collect material for urease tests and histologic studies, with hematoxylin-eosin and fucsin stains in order to identify the microorganism. The gold standard used to detect the presence of H pylori was an analysis of the combined results from the gastric biopsies by urease test and histological method. RESULTS: Antral exfoliative cytology method exhibited 90.3% sensitivity, 66.6% specificity, accuracy of 81.6%, positive predictive value of 82.3% and negative predictive value of 80.0%, in this population with a prevalence of 63.3%.CONCLUSION: Antral exfoliative cytology was demonstrated to be a sensitive, accurate and easy to perform method for investigating H pylori infection in the stomach.

关键词： H pylori Exfoliative cytology Stomach

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