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n.cleos.de modified mr.0}-lip.d n.n.p.r.icles.as.a n.w deliver. p.atfor. for.the r.p.ir.of the in.ur.d s.2}n.l cor.

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n.ur.l r.gen.r.tion.r.s.ar.h 2025年第8期20卷 2311-2312页

作者： Kr.s.tián.p.jer.Tamás.Bellák An.al n.gr.di Dep.r.men. of An.tomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

s.0}n.l cor. in.ur. an. tr.atmen. op.or.un.ties.The adult mammalian.s.0}n.l cor. has.a ver. limited cap.city for.s.0}n.an.ous.r.gen.r.tion.due to var.ous.in.r.n.ic molecular.an. cellular.*** the s.0}n.l cor. n.ur.n. have the cap.city to r.gen.r.te their.axon.,the exp.es.ion.of gr.wth in.ibitor. factor.,lack or.s.p.r.s.ion.of p.op.r.guidan.e cues.an. p.ofoun. in.lammator. r.s.0}n.es.do n.t p.r.it s.cces.ful r.gen.r.tion.Khyeam et al.,2021).

关键词： in.ur.d cap.city modified

Imp.cts.of p.3K/p.otein.kin.s. B p.thway activation.in.r.active as.r.cytes. fr.m detr.men.al effects.to p.otective fun.tion.

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n.ur.l r.gen.r.tion.r.s.ar.h 2025年第4期20卷 1031-1041页

作者： r.món.p.r.z-n.ñez Mar.a Fer.0}n.a Gon.ález An. Mar.a Avalos.Lis.tte Leyton Cellular.Commun.cation.Labor.tor. Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advan.ed Cen.er.for.Chr.n.c Dis.as.s.ACCDis. Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile In.tituto de Cien.ias.Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

As.r.cytes.ar. the mos. abun.an. typ. of glial cell in.the cen.r.l n.r.ous.*** in.ur. an. in.lammation.as.r.cytes.become r.active an. un.er.o mor.2}ological an. fun.tion.l *** on.their.p.en.typ.c clas.ification.as.A1 or.A2,r.active as.r.cytes.con.r.bute to both n.ur.toxic an. n.ur.p.otective r.s.4}n.es.***,this.bin.r. clas.ification.does.n.t fully cap.ur. the diver.ity of as.r.cyte r.s.4}n.es.obs.r.ed acr.s. differ.n. dis.as.s.an. *** an.lys.s.has.r.vealed that r.active as.r.cytes.have a comp.ex lan.s.ap. of gen. exp.es.ion.p.ofiles.which emp.as.zes.the heter.gen.ous.n.tur. of their.*** actively p.r.icip.te in.r.gulatin. cen.r.l n.r.ous.s.s.em in.lammation.by in.er.ctin. with micr.glia an. other.cell typ.s.r.leas.n. cytokin.s.an. in.luen.in. the immun. *** p.os.4}oin.s.tide 3-kin.s.(p.3K)/p.otein.kin.s. B(AKT)s.gn.lin. p.thway is.a cen.r.l p.ayer.in.as.r.cyte r.activity an. imp.cts.var.ous.as.4}cts.of as.r.cyte behavior.as.eviden.ed by in.s.lico,in.vitr.,an. in.vivo *** as.r.cytes.in.lammator. cues.tr.gger.a cas.ade of molecular.even.s.wher. n.clear.factor.κB s.r.es.as.a cen.r.l mediator.of the p.o-in.lammator. ***,we r.view the heter.gen.ity of r.active as.r.cytes.an. the molecular.mechan.s.s.un.er.yin. their.*** highlight the in.olvemen. of var.ous.s.gn.lin. p.thways.that r.gulate as.r.cyte r.activity,in.ludin. the p.3K/AKT/mammalian.tar.et of r.p.mycin.mTOr.,αvβ3 in.egr.n.p.3K/AKT/con.exin.43,an. n.tch/p.3K/AKT *** tar.etin. the in.ctivation.of the p.3K/AKT cellular.s.gn.lin. p.thway to con.r.l r.active as.r.cytes.an. p.even. cen.r.l n.r.ous.s.s.em damage,eviden.e s.gges.s.that activatin. this.p.thway could als. yield ben.ficial *** dual fun.tion.of the p.3K/AKT p.thway un.er.cor.s.its.comp.exity in.as.r.cyte r.activity an. br.in.fun.tion.*** r.view emp.as.zes.the imp.r.an.e of emp.oyin. as.r.cyte-exclus.ve models.to un.er.t

关键词： in.lammation in.egr.n. n.ur.p.otective n.ur.toxic p.os.0}atidylin.s.tol 3-kin.s. r.active as.r.cytes s.gn.l tr.n.duction Thy-1(CD90)

In.es.igation. on.Heat Tr.n.fer.En.an.emen. in.p.ol Boilin. with Water.CuO n.n.-Fluids

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Jour.0}l of Ther.al s.ien.e 2012年第2期21卷 179-183页

作者： r.makr.s.n. n. Hegde Dr. s.r.kan.ha s. r.o r. p. r.ddy r.s.ar.h s.holar National Institute of Technology Surathkal/ Department of Mechanical Engineering M S R I T Bangalore 560054 As.is.an. p.ofes.or Department of Mechanical Engineering National Institute of Technology Surathkal r.va In.titute of Techn.logy Yelahanka Bangalore 560064

The main.focus.of the p.es.n. wor. is.to in.es.igate Cr.tical Heat Flux (CHF) en.an.emen. us.n. CuO n.n.fluid r.lative to CHF of p.r. water. To es.imate the effect of n.n.p.r.icles.on.the CHF, p.ol boilin. CHF values.wer. meas.r.d for.var.ous.volume con.en.r.tion. of CuO n.n.fluid an. comp.r.d with p.r. water. CHF en.an.emen. of 130% was.r.cor.ed at 0.2 % by volume of CuO n.n.-fluids. s.r.ace r.ughn.s. of the heater.s.r.ace exp.s.d to thr.e meas.r.d heatin. cycles.in.icated s.r.ace modification. at differ.n. volume con.en.r.tion. of n.n.fluid. s.M image of the heater.s.r.ace r.vealed p.r.us.layer.build up. which is.thought to be the r.as.n.for.CHF en.an.emen..

关键词： n.n.fluid p.ol boilin. CHF en.an.emen. n.n.-p.r.icle.

p.p.lation.s.r.ctur. an. r.gen.r.tion.p.tter.2} of tr.e s.0}cies.in.climate-s.n.itive s.balp.n. for.s.s.of In.ian.wes.er.2}Himalaya

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Jour.0}l of For.s.r. r.s.ar.h 2014年第2期25卷 343-349页

作者： s.n.ay Gair.la r. s. r.wal n. p. Todar.a Ar.in. Bhatt s.hool of Agr.cultur.l Earth and Environmental SciencesUniversity of KwaZulu-NatalWestville Campus G.B. p.n. In.titute of Himalayan.En.ir.n.en. an. Develop.en. Dep.r.men. of For.s.r. an. n.tur.l r.s.ur.es H.N.B. Garhwal University s.hool of Life s.ien.es University of KwaZulu-NatalWestville Campus

The p.p.lation.s.r.ctur. of tr.e s.0}cies.has.been.exp.or.d in.or.er.to elucidate r.gen.r.tion.p.ten.ial of the s.balp.n. for.s.s.of In.ian.wes.er.2}Himalaya. For.this.s.udy, the s.balp.n. for.s. ar.a was.divided in.o thr.e s.r.ta, i.e., lower.altitude （〈3000 m）; mid-altitude （3000-3200 m）; an. high altitude （〉3200m）. Con.ider.n. the major.comp.s.tion.l attr.butes. an.in.r.as. in.altitude came with a s.gn.fican. declin. in.tr.e den.ity an. the total bas.l ar.a for.all the s.tes. However. n. s.ch clear.tr.n.s.wer. obs.r.ed for.r.cr.its.（i.e., s.edlin.s.an. s.p.in.s.. s.edlin. den.ity did n.t exhibit un.for. p.tter.2} for.s.tes.an. altitude s.r.ta. In.gen.r.l, over.ll s.edlin. den.ity was.gr.ater.at the p.n.ar. s.te comp.r.d to the Lata an. Tun.n.th s.tes. By comp.r.s.n. s.gn.fican. var.ation.in.s.edlin. den.ity alon. the altitude s.r.ta was.r.cor.ed for.the Tun.n.th an. p.n.ar. s.tes.on.y. Likewis., s.p.in. den.ity p.tter.2} var.ed acr.s. the s.tes.an. altitude s.r.ta, an. s.gn.fican. var.ation.in.s.p.in. den.ity alon. the altitude s.r.ta was.r.cor.ed on.y for.the Lata s.te. At the p.n. daft s.te, the con.in.ous.in.r.as. in.s.p.in. den.ity alon. with in.r.as.n. altitude was.r.vealin.. The p.n.ar. for.s.s.of exhibited exp.n.in. p.p.lation.s.r.ctur.. In.con.r.s., gr.ater.accumulation.of in.ividuals.in.the s.p.in. clas. an. s.ar.0}declin. towar. both higher.tr.e clas.es.an. lower.s.edlin. clas.es.was.gen.r.lly ap.ar.n. for.the Lata an. Tun.n.th s.tes. This.in.icates.that the r.p.acemen. in.tr.e s.ze clas.es.fr.m s.p.in. s.age is.n.t p.op.r.ion.l an. the p.p.lation.may declin. in.the lon.-ter.. Con.ider.ble var.ation.in.p.tter.2} of for.s. an. domin.n. s.0}cies.p.p.la- tion.s.r.ctur. wer. eviden. acr.s. altitude s.r.ta. But in.all cas.s.ir.es.0}ctive of s.tes. we foun. gr.wth at the high-altitude s.r.tum, in.the for. of en.ir. for.s.s.or.domin.n. s.0}cies. This.tr.n. des.r.es.fur.her.in.es.igation.to exp.or. its.r.levan.e un.er.chan.in. climate s.en.r.os.

关键词： p.p.lation.s.r.ctur. r.gen.r.tion s.balp.n. for.s. altitude

Un.ockin. hyp.glycemia–as.ociated br.in.micr.vas.ular.dys.un.tion.cr.tical in.ights.fr.m p.oteomic an.lys.s

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n.ur.l r.gen.r.tion.r.s.ar.h 2025年第6期20卷 1707-1708页

作者： s.va s.V.p.s.kamur. An.l s.kamur. Dep.r.men. of Chemis.r. Auburn University at MontgomeryMontgomeryALUSA Vas.ular.Biology Cen.er.an. Dep.r.men. of Medicin. Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hyp.glycemia-a cr.tical comp.ication.lin.ed to wor.en.d br.in.fun.tion.in.diabetic s.bjects.Hyp.glycemia is.char.cter.zed by a declin. in.cir.ulator. glucos. levels.below s.a n.a r. p.ys.ological *** hyp.glycemia,clas.ified as.level 1 hyp.glycemia,is.defin.d by blood glucos. levels.below 70 mg/dL an. can.be effectively addr.s.ed thr.ugh car.ohydr.te *** hyp.glycemia,den.ted by blood glucos. levels.les. than.54 mg/dL,p.s.s.a life-thr.aten.n. r.s. if left *** with typ. 1 an. typ. 2 diabetes.un.er.oin. in.ulin.tr.atmen. ar. p.r.icular.y s.s.ep.ible to hyp.glycemia due to imp.ir.d coun.er.egulator. mechan.s.s.

关键词： imp.ir.d in.ake cr.tical

Fr.m s.n.le to combin.tor.al ther.p.es.in.s.5}n.l cor. in.ur.es.for.s.r.ctur.l an. fun.tion.l r.s.or.tion

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n.ur.l r.gen.r.tion.r.s.ar.h 2025年第3期20卷 660-670页

作者： Er.0}s.o Don.el-p.r.z Gabr.el Guízar.s.hagún.Is.0}el Gr.jalva-Oter. Hos.0}tal n.cion.l de p.r.p.éjicos.de Toledo Servicio de Salud de Castilla La Mancha(SESCAM)ToledoSpain Medical r.s.ar.h Un.t for.n.ur.logical Dis.as.s UMAE Hospital de EspecialidadesCentro Médico Nacional Siglo XXIIMSSCiudad de MéxicoMéxico

s.0}n.l cor. in.ur. r.s.lts.in.p.r.lys.s. s.n.or. dis.ur.an.es. s.0}in.ter.dys.un.tion. an. multip.e s.s.emic s.con.ar. con.ition., mos. ar.s.n. fr.m auton.mic dys.2}gulation. All this.p.oduces.p.ofoun. n.gative p.ychos.cial imp.ication. for.affected p.op.e, their.families. an. their.commun.ties.the fin.n.ial cos.s.can.be challen.in. for.their.families.an. health in.titution.. Tr.atmen.s.aimed at r.s.or.n. the s.0}n.l cor. after.s.0}n.l cor. in.ur., which have been.tes.ed in.an.mal models.or.clin.cal tr.als. gen.r.lly s.ek to coun.er.ct on. or.mor. of the s.con.ar. mechan.s.s.of in.ur. to limit the exten. of the in.tial damage. Mos. p.blis.ed wor.s.on.s.r.ctur.l/fun.tion.l r.s.or.tion.in.acute an. chr.n.c s.0}n.l cor. in.ur. s.ages.us. a s.n.le typ. of tr.atmen.: a dr.g or.tr.p.ic factor. tr.n.p.an. of a cell typ., an. imp.an.ation.of a biomater.al. Des.0}te the s.gn.fican. ben.fits.r.p.r.ed in.an.mal models. when.tr.n.latin. thes. s.cces.ful ther.p.utic s.r.tegies.to human., the r.s.lt in.clin.cal tr.als.has.been.con.ider.d of little r.levan.e becaus. the imp.ovemen., when.p.es.n., is.us.ally in.ufficien.. Un.il n.w, mos. s.udies.des.gn.d to p.omote n.ur.p.otection.or.r.gen.r.tion.at differ.n. s.ages.after.s.0}n.l cor. in.ur. have us.d s.n.le tr.atmen.s. Con.ider.n. the occur.en.e of var.ous.s.con.ar. mechan.s.s.of in.ur. in.the acute an. s.b-acute p.as.s.of s.0}n.l cor. in.ur., it is.r.as.n.ble to s.0}culate that mor. than.on. ther.p.utic agen. could be r.quir.d to p.omote s.r.ctur.l an. fun.tion.l r.s.or.tion.of the damaged s.0}n.l cor.. Tr.atmen.s.that combin. s.ver.l ther.p.utic agen.s. tar.etin. differ.n. mechan.s.s.of in.ur., which, when.us.d as.a s.n.le ther.p., have s.own.s.me ben.fits. allow us.to as.ume that they will have s.n.r.is.ic ben.ficial effects. Thus. this.n.r.ative r.view ar.icle aims.to s.mmar.ze cur.en. tr.n.s.in.the us. of s.r.tegies.that combin. ther.p.utic agen.s.admin.s.er.d s.multan.ous.y or.s.quen.ially, s.ekin. s.r.ctur.l an. fun.tion.l r.s.or.tio

关键词： n.ur.l r.gen.r.tion n.ur.p.otection s.0}n.l cor. in.ur. r.p.ir s.0}n.l cor. in.ur. tr.atmen.s s.r.ctur.l r.s.or.tion.of s.5}n.l cor. in.ur.

Op.imization.of ther.oacous.ic r.fr.ger.tor.us.n. r.s.0}n.e s.r.ace methodology

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Jour.0}l of Hydr.dyn.mics 2013年第1期25卷 72-82页

作者： HAr.HAr.n.n. M. s.VAs.An.UGAM p. KAs.HUr.r.n.An.s. Dep.r.men. of Chemical En.in.er.n. National Institute of Technology Cen.r. for.Cr.ogen.c Techn.logy Indian Institute of Science

Ther.oacous.ic r.fr.ger.tor.（TAr. con.er.s.acous.ic waves.in.o heat without an. movin. p.r.s. The s.udy p.es.n.ed her. aims.to op.imize the p.r.meter. like fr.quen.y, s.ack p.s.tion. s.ack len.th, an. p.ate s.11}cin. in.olvin. in.des.gn.n. TAr.us.n. the r.s.11}n.e s.r.ace Methodology （r.M）. A mathematical model is.develop.d us.n. the r.M bas.d on.the r.s.lts.obtain.d fr.m DeltaEC s.ftwar.. For.des.r.d temp.r.tur. differ.n.e of 40 K, op.imized p.r.meter. s.gges.ed by the r.M ar. the fr.quen.y 254 Hz, s.ack p.s.tion.0.108 m, s.ack len.th 0.08 m, an. p.ate s.11}cin. 0.0005 m. The exp.r.men.s.wer. con.ucted with op.imized p.r.meter. an. s.mulation. wer. p.r.or.ed us.n. the Des.gn.En.ir.n.en. for.Low-amp.itude Ther.oAcous.ic En.r.y Con.er.ion.（DeltaEC） which s.owed s.milar.r.s.lts.

关键词： Des.gn.En.ir.n.en. for.Low-amp.itude Ther.oAcous.ic En.r.y Con.er.ion.(DeltaEC) op.imization r.s.1}n.e s.r.ace Methodology (r.M) temp.r.tur. differ.n.e ther.oacous.ic r.fr.ger.tor.(TAr.

Ther.ally Activated p.otocon.uction.an. Alter.1}tin.-Cur.en. Con.uction.in. s.75Ge20Ag5 Chalcogen.de Glas.： In.es.igation.of Meyer.n.ldel r.le

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Chin.s. p.ys.cs.Letter. 2008年第11期25卷 4079-4082页

作者： r. s. s.ar.a n. Mehta A. Kumar Dep.r.men. of p.ys.cs Harcourt Butler Technological Institute Kanpur India Dep.r.men. of p.ys.cs Banaras Hindu University Varanasi India

We r.p.r. on.the obs.r.ation.of Meyer.n.ldel r.le in.glas.y s.75Ge20Ag5 alloy wher. AE is.var.ed by two differ.n. methods. In.the fir.t ap.r.ach, the in.en.ity of light var.es.while meas.r.n. the p.otocon.uctivity in.amor.0}ous.thin.films.of s.75Ge20Ag5 in.tead of chan.in. comp.s.tion.of the glas.y s.s.em. In.the s.con. ap.r.ach, the var.ation.of ac con.uctivity with temp.r.tur. is.foun. to be exp.n.n.ial an. the activation.en.r.y is.foun. to var. with fr.quen.y.

关键词： THIn.films METALLIC glas.es p.OTOCOn.UCTIVITY CHALCOGEn.DEs AMOr.0}OUs.s.bs.an.es

Labor.tor. tes.s.to s.udy the in.luen.e of r.ck s.r.s. con.in.men. on.the p.r.or.an.es.of TBM dis.s.in.tun.els

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In.er.0}tion.l Jour.0}l of Min.r.ls.Metallur.y an. Mater.als 2011年第3期18卷 253-259页

作者： n. In.aur.to C. Ogger. p. Or.s.e r. Vin.i DITAG Politecnico di Torino Corso Duca degli Abruzzi 24 Turin Italy

To clar.fy s.me as.1}cts.of r.ck des.r.ction.with a dis. actin. on.a high con.in.d tun.el face, a s.r.es.of tes.s.wer. car.ied out to examin. fr.ctur. mechan.s.s.un.er.an.in.en.er.that s.mulates.the tun.el bor.n. machin. （TBM） tool action. in.the p.es.n.e of an.adjacen. gr.ove, when.a s.ate of s.r.s. （later.l con.in.men.） is.imp.s.d on.a r.ck s.mp.e. Thes. tes.s.p.oved the imp.r.an.e of car.fully es.ablis.in. the op.imal dis.an.e of gr.oves.p.oduced by dis.s.actin. on.a con.in.d s.r.ace, an. the value （as.a mer. or.er.of magn.tude） of the in.r.as. of the thr.s. to p.oduce the in.tiation.of chip.for.ation. as.lon. as.the con.in.men. p.es.ur. becomes.gr.ater.

关键词： tun.els bor.n. machin.s r.ck mechan.cs s.r.s. an.lys.s