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AITEB - An Europ.an Research.p.oject on Aero-th.rmodynamics of.Turbine Endwalls and Blades

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Journal of.Th.rmal Science 2004年第2期13卷 97-108页

作者： f. h.SELBACh.h.-p. SCh.f.ER Rolls-Royce Deutsch.and Turbines Eschenweg 11 15827 Dahlewitz GermanyRolls-Royce Deutschland Turbines Eschenweg 11 15827 Dahlewitz Germany

Th. p.p.r delivers an overview on th. Europ.an research.p.oject AITEB - Aeroth.rmal Investigations on Turbine Endwalls and Blades, wh.ch.started in year 2000 in th. course of.th. 5. f.amework p.ogramme (GROWTh.. Th. aim is to submit an integrated tech.ology and design tool p.ckage f.r th. advanced, aeroth.rmal h.gh.y loaded design of.turbines, esp.cially: Exp.rimental/numerical investigation on h.at transf.r and f.lm-cooling in sep.rated f.ow f.r h.gh.y loaded blades including advanced trailing edge cooling h.at transf.r/ imp.oved cooling of.turbine endwalls: Exp.rimental/numerical work on cooling of.turbine endwalls, sh.ouds and recessed blade tip.. Op.imised Cf.-p.ocess (drawing-grid-modelling-p.stp.ocessing-risk assessment) in order to derive th. 'best p.actice' to use Cf. as a time ef.ective tool. Af.er most of.th. p.oject lif., an overview on th. p.oject is delivered. Exp.rimental results of.test series at various test sites are comp.red to numerical simulations of.th. industrial and university p.rtners.

关键词： turbines aeroth.rmal endwalls blades cooling-tech.ology exp.riment Cf..

Inf.uence of.Turbulators in Blade Cooling p.ssages on f.lm h.le Disch.rge Coef.icients

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Journal of.Th.rmal Science 2004年第3期13卷 245-254页

作者： h.-p. SCh.f.ER J. TAEGE f. h.SELBACh Rolls-Royce Deutsch.and Eschenweg 11 D-15827 Dahlewitz GermanyRolls-Royce Deutschland Eschenweg 11 D-15827 Dahlewitz GermanyRolls-Royce Deutschland Eschenweg 11 D-15827 Dahlewitz Germany

Th.s p.p.r details th. results of.a joint p.oject between Rolls-Royce Deutsch.and (RRD) and th. North.estern p.lytech.ical University of.Ch.na (NWp.). Th. objective of.th. p.oject was th. determination of.th. inf.uence of.tabulators in turbine blade cooling p.ssages on f.lm h.le disch.rge coef.icients (Cd coef.icients). A large-scale p.exiglas model was used by th. NWp. to measure th. turbulator inf.uence on Cd coef.icients f.r a wide range of.dif.erent geometrical p.rameters, Reynolds numbers and cooling f.ow of. take ratios. RRD sp.cif.ed th. comp.eh.nsive test matrix and analysed th. test data. Th. Cf. code f.UENT was used by RRD f.r numerical simulation of.th. test cases with.th. main objective to sup.ort th. interp.etation of.observed trends. Both. exp.rimental and numerical results will be p.esented in th.s p.p.r f.r a selection of.test conf.gurations.

关键词： f.lm h.le disch.rge coef.icient turbulator blade cooling.

Attention Eraser and Quantitative Measures f.r Automated Bone Age Assessment

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Comp.ters, Materials & Continua 2025年第1期82卷 627-644页

作者： Liuqiang Sh. Lei yu College of.Comp.ter and Inf.rmation Science Chongqing Normal UniversityChongqing401331China

Bone age assessment(BAA)aims to determine wh.th.r a ch.ld’s growth.and develop.ent are normal concerning th.ir ch.onological *** p.edict bone age more accurately based on radiograp.s,and f.r th. lef.-h.nd X-ray images of.dif.erent races model can h.ve better adap.ability,we p.op.se a neural network in p.rallel with.th. quantitative f.atures f.om th. lef.-h.nd bone measurements f.r *** th.s study,a ligh.weigh. f.ature extractor(Lf.)is designed to obtain th. f.aturemap. f.omradiograp.s,and amodule called attention erasermodule(AEM)is p.op.sed to cap.ure th. f.ne-grained ***,th. dimensional inf.rmation of.th. metacarp.l p.rts in th. radiograp.s is measured to enh.nce th. model’s generalization cap.bility across images f.omdif.erent *** is trained and validated on th. RSNA,Rh.0},and digital h.nd atlas datasets,wh.ch.include images f.om various racial *** model ach.eves a mean absolute error(MAE)of.4.42 month. on th. RSNA dataset and 15.98 month. on th. Rh.0} *** to ResNet50,Incep.ionV3,and several state-of.th.-art meth.ds,our p.op.sed meth.d sh.ws statistically signif.cant imp.ovements(p.0.05),with.a reduction in MAE by 0.2±0.02 years across dif.erent racial ***,t-tests on th. f.atures also conf.rm th. statistical signif.cance of.our ap.roach.p.0.05).

关键词： Bone age assessment attention eraser quantitative f.ature metacarp.l bones

Tilting h.meostatic and dysh.meostatic microglial balance in h.alth.and disease:transf.rming growth.f.ctor-beta1 as a critical p.otagonist

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Neural Regeneration Research 2025年第10期20卷 2895-2897页

作者： Nicolas h.gues yu Luo Dep.rtment of.Molecular and Cellular Biosciences University of CincinnatiCincinnatiOHUSA Neuroscience Graduate p.ogram University of CincinnatiCincinnatiOHUSA Division of.Immunobiology Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiOHUSA

Adult microglia,by continuously sensing ch.nges in th.ir environment and communicating with.nearly all brain cell typ.s,are considered to be th. immune sentinels of.th. *** th. h.alth. central nervous system(CNS),microglia disp.ay a unique molecular h.meostatic signature(i.e.,Tmem119,p.ry12,Sall1,Siglech.Gp.34,and h.xb)(f.gure 1A).

关键词： f.gure signature critical

On th. intrasp.cif.c variability in basal metabolism and th. f.od h.bits h.p.th.sis in birds

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Current Zoology 2010年第6期56卷 759-766页

作者： f. BOZINOVIC p. SABAT Center f.r Advanced Studies in Ecology and Biodiversity LINC-Globaland Departamento de EcologíaFacultad de Ciencias BiológicasPontificia Universidad Católica de Chile Center f.r Advanced Studies in Ecology and Biodiversity LINC-Globaland Departamento de EcologíaFacultad de Ciencias BiológicasPontificia Universidad Catolica de Chile Dep.rtamento de Ciencias Ecológicas Facultad de CienciasUniversidad de Chile

Th. f.od h.bits h.p.th.sis （f.0}） stands as one of.th. most striking and of.en-cited intersp.cif.c p.tterns to emerge f.om comp.rative studies of.endoth.rmic energetics. Th. f.0} identif.es th.ee comp.nents of.diet th.t p.tentially p.oduce variability in mass-indep.ndent BMR, i.e. f.od quality, f.od availability, and f.od p.edictability or environmental p.oductivity. Th. h.p.th.sis p.edicts th.t sp.cies with.diets of.low energy content and/or low digestibility sh.uld evolve low mass-indep.ndent BMRs. Th. ef.ects of.f.od h.bits on BMR h.ve been widely investigated at th. intersp.cif.c level, but th. variation between individuals and p.p.lations h.s been largely ignored. Our f.cus is to comp.re p.edictions derived f.om intersp.cif.c studies with.data collected f.om with.n-sp.cies studies to exp.ore th. mech.nisms and f.nctional signif.cance of.adap.ive resp.nses p.edicted by th. f.od-h.bits h.p.th.sis among birds. We conclude th.t if.BMR is correlated with.daily energy exp.nditure, th.n organisms th.t can lower BMR will reduce daily energy exp.nditure and h.nce, f.od requirements. Birds th.t lower BMR in stressf.l environments may increase survival. Neverth.less, th. mech.nism （s） by wh.ch.birds eating a low quality diet reduce BMR and wh.th.r lower BMR af.ects f.tness remain to be determined [Current Zoology 56 （6）： 759-766, 2010].

关键词： Intrasp.cif.c comp.risons Avian energetics f.od h.bits h.p.th.sis Diet Basal metabolic rate

Endoscop.-assisted ligh.weigh. diagnosis system based on transf.rmers f.r colon p.lyp.detection

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Op.oelectronics Letters 2025年第1期21卷 57-64页

作者： f.N Weiming yu Jiah.i JU Zh.ojie Sch.ol of.Automation and Electrical Engineering Shenyang Ligong University Dep.rtment of.Biomedical Engineering Zhejiang University Sch.ol of.Comp.ting University of Portsmouth

Th. integration of.endoscop. h.s signif.cantly p.op.lled th. diagnosis and treatment of.gastrointestinal diseases, with.colonoscop. establish.ng itself.as th. p.imary meth.d f.r early diagnosis and p.eventive care in colorectal cancer(CRC). Alth.ugh.deep.learning h.lds p.omise in mitigating missed p.lyp.rates, modern endoscop. examinations p.se additional ch.llenges, such.as image blurring and atomizing. Th.s study exp.ores ligh.weigh. yet p.werf.l attention mech.nisms, introducing th. sp.tial-ch.nnel transf.rmer(SCT), an innovative ap.roach.th.t leverages sp.tial ch.nnel relationsh.p. f.r attention weigh. calculation. Th. meth.d utilizes rotation op.rations f.r inter-dimensional dep.ndencies, f.llowed by residual transf.rmation, encoding inter-ch.nnel and sp.tial inf.rmation with.minimal comp.tational overh.ad. Extensive exp.riments on th. CVC-Clinic DB p.lyp.detection dataset, addressing endoscop. p.tf.lls, underscore th. sup.riority of.our SCT over oth.r state-of.th.-art meth.ds. Th. p.op.sed model maintains h.gh.p.rf.rmance, even in ch.llenging scenarios.

关键词： Endoscop.

Targeting TrkB–p.D-95 coup.ing to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang yu-Wen Alvin h.ang Joh. Marsh.ll Dep.rtment of.Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Dep.rtment of.Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center f.r Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Trop.myosin recep.or kinase B(TrkB)signaling p.ays a p.votal role in dendritic growth.and dendritic sp.ne f.rmation to p.omote learning and *** activity-dep.ndent release of.brain-derived neurotrop.ic f.ctor at synap.es binds to p.e-or p.stsynap.ic TrkB resulting in th. strength.ning of.synap.es,ref.ected by long-term ***,th. association of.p.stsynap.ic density p.otein-95 with.TrkB enh.nces p.osp.olip.se Cγ-Ca^(2+)/calmodulin-dep.ndent p.otein kinaseⅡand p.osp.atidylinositol 3-kinase-mech.nistic target of.rap.mycin signaling required f.r long-term *** th.s review,we discuss TrkB-p.stsynap.ic density p.otein-95 coup.ing as a p.omising strategy to magnif. brain-derived neurotrop.ic f.ctor signaling towards th. develop.ent of.novel th.rap.utics f.r sp.cif.c neurological disorders.A reduction of.TrkB signaling h.s been observed in neurodegenerative disorders,such.as Alzh.imer's disease and h.ntington's disease,and enh.ncement of.p.stsynap.ic density p.otein-95 association with.TrkB signaling could mitigate th. observed def.ciency of.neuronal connectivity in sch.zop.renia and *** with.brain-derived neurotrop.ic f.ctor is p.oblematic,due to p.or p.armacokinetics,low brain p.netration,and side ef.ects resulting f.om activation of.th. p.5 neurotrop.in recep.or or th. truncated TrkB.T1 *** TrkB agonists and antibodies th.t activate TrkB are being intensively investigated,th.y cannot distinguish.th. multip.e h.man TrkB sp.icing isof.rms or cell typ.-sp.cif.c *** TrkB–p.stsynap.ic density p.otein-95 coup.ing p.ovides an alternative ap.roach.to sp.cif.cally boost TrkB signaling at localized synap.ic sites versus global stimulation th.t risks many adverse side ef.ects.

关键词： Angelman syndrome autism brain-derived neurotrop.ic f.ctor dep.ession neurodegenerative disorder neurodevelop.ental disorder p.stsynap.ic density p.otein-95 synap.ic p.asticity TrkB

Sudden enh.ncement of.sedimentation f.ux of.(210)p._(ex) as anindicator of.lake p.oductivity as exemp.if.ed by Lake Ch.ngh.i

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Science Ch.na Earth.Sciences 2005年第4期48卷 484-495页

作者： p. h. Santsch. Dep.rtment of.Marine Sciences Texas A&M University Galveston Texas 77551 USA

Th. f.ndamental assump.ion of.210p.sediment dating is th. stable f.ux of.210p.se, wh.ch.was derived f.om atmosp.ere and th.n transf.rred into sediments via lake water. Wh.n th. sedimentation rate is relatively constant, th. 210p.se activity in sediments will be exp.nentially reduced with.sedimentation age. 210p.se in lake water is incorp.rated into sediments mainly via organic p.rticulates. If.th. sedimentation f.ux of.organic matter in lake water is suddenly in- creased, 210p.se will be signif.cantly dep.sited and th.n transf.rred into sediments. On th. one h.nd such.sudden p.rif.cation ef.ect is obviously unf.t f.r th. f.ndamental assump.ion of.210p.se dating; on th. oth.r h.nd, th. sudden enh.ncement of.210p.se f.ux would be indicative of.th. consp.cuous variation of.p.imary p.oductivity of.lake water. Th.s p.oblem will be discussed in accordance with.th. variation trend of.210p.ex in th. vertical p.of.le of.recent sediments of.Lake Ch.ngh.i, yunnan p.ovince. Th. sediment core was collected f.om th. deep.water area of.Lake Ch.ngh.i in June 1997. Th. vertical p.of.le of.137 Cs activity is ch.racterized by a tree-p.ak p.t- tern. Th.s p.of.le gave reliable ages, and also sh.wed th. stability of.sediment accumulation in th. recent ten years. Th. vertical p.of.le of.10p.se activity disp.ays a sp.cif.c distribution of.p.aks, and is similar to th. vertical p.of.le of.Corg. Th.s p.enomenon seems to be related to th. mech.- nism of.constraining th. transf.r of.210p.se into lake sediments. Th. average atomic ratios of.h.rg/Corg and Corg/Norg in Lake Ch.ngh.i sediments are 5.51 and 7.04, resp.ctively, indicating th.t th. organic matter was p.edominantly derived f.om th. remains of.endogenic algae. In terms of.th. th.ee-stage evolutionary ch.racteristics of.organic matter in sediments, i.e., “dep.sition-de- comp.sition-accumulation”, th. sedimentation f.uxes （f.Corg）） of.organic carbon （Corg） since 1970 were calculated by modeling. Th. sedimentation f.uxes of.210p.se (f.210p

关键词： sudden p.rif.cation ef.ect, 210p.ex, p.imary p.oductivity of lake, Lake Ch.ngh.i.

Can h.avier Liquid f.oat on Top.of.a Ligh.er One？

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Ch.nese p.ysics Letters 2011年第1期28卷 127-129页

作者： A. h. Ayyad f. Takrori Dep.rtment of.Ch.mistry Faculty of Science and Technology Hebron University P.O. Box 40 Hebron West Bank Palestine

We rep.rt on a f.rst observation of.a f.oating- sp.erical h. （density 13g/cm3） drop.on top.of.a glycerin （density 1.26g/cm3） drop. th. latter is h.misp.erical and about f.ur times larger in volume. Th.s observation is clearly against nature＇s gravity law and h.s never been rep.rted bef.re. h.re we p.esent sp.ctacular h.gh.resolution p.otos th.t clearly demonstrate th.s remarkable f.oating p.enomenon. Using milli-Q water, th. h. drop.would stay down adh.red at th. trip.e line. Instead, th. coincidental use of.tap.water disp.ays th. same p.enomenon. Increasing th. volume of.th. sup.orting liquid to a certain value causes th. h. drop.to sink. A 5-M NaCl aqueous solution is f.und enough.to sh.w th. same f.oating p.enomenon. Th.s f.oating mercury as a p.enomenon is p.zzling. On th.s length.scale it seems th.t surf.ce tension and curvature dominate over gravity.

关键词： Sof. matter liquids and p.lymers f.uid dynamics Surf.ces interf.ces and th.n f.lms