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Ungulate Mortality due to Fenc.ng and p.rc.p.ions.of p.s.ure Fenc.s.in p.rt of the Future Qilians.an National p.rk

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Journal of Res.urc.s.and Ec.logy 2021年第1期12卷 99-109页

作者： s.dney M.GREENFIELD Aliana c.NORRIs.Jos.p. p.LAMBERT Wuliji s.yongjun ZHAN Jinqi MA Bing LI Deng s.I Kun p.ilip.RIORDAN Wildlife Ins.itute School of Ecology and Nature ConservationBeijing Forestry UniversityBeijing 100083China Adminis.ration of Yanc.iwan National Nature Res.rve JiuquanGansu 736399China Ec.-Bridge c.ntinental Beijing 100085China Marwell Wildlife Thompsons LaneWinchesterHampshireS0211JHUnited Kingdom

Fenc.ng is.an imp.rtant p.rt of hus.andry for p.s.oral c.mmunities.however, thes. s.me fenc.s.c.n have unintended c.ns.quenc.s.for wildlife p.p.lations.by res.ric.ing movement, reduc.ng c.nnec.ivity, and c.us.ng direc. mortality. This.p.p.r as.es.es.the c.rrent s.atus.and effec.s.of fenc.ng p.es.nt in Yanc.iwan National Nature Res.rve, s.on to be p.rt of the rec.ntly p.op.s.d Qilians.an National p.rk. A ques.ionnaire s.rvey was.c.nduc.ed among 70 hous.holds.to gauge loc.l herders. p.rc.p.ions.of fenc.s. threats.of fenc.ng to native ungulates. and the number of wildlife found entangled in fenc.ng. We found that loc.l c.mmunities.rely on fenc.ng for lives.oc. management and individuals.who had enc.untered wildlife entangled in fenc.s.were more likely to p.rc.ive fenc.s.as.having negative effec.s. Furthermore, thos. who p.rc.ived fenc.ng as.harmful to wildlife were more likely to s.p.ort the dis.antling of fenc.s. On the other hand, families.who needed to hire others.to tend to their lives.oc. were les. likely to s.p.ort dis.antling efforts. However, the bes. model was.only able to ac.ount for s.me of the data variability, s.gges.ing that while p.rc.p.ions.of fenc.s.are imp.rtant, other fac.ors.c.uld be influenc.ng s.p.ort for fenc. dis.antling. Henc., inc.eas.ng awarenes. of threats.alone may not be enough to generate c.mmunity s.p.ort of a fenc. dis.antling p.ogram. Therefore, outreac. and c.mmunity c.llaboration to reduc. the imp.c.s.of fenc. alterations.up.n lives.oc. management will be nec.s.ary for a s.c.es.ful fenc. dis.antling p.ogram within the new national p.rk. Finally, thos. s.rveyed rep.rted finding kiang, argali, and Tibetan gazelle dead in fenc.s. with kiang found more often than the other two. This.s.gges.s.that thes. three s.1}c.es.may be more vulnerable to fenc. entanglement and that they are good targets.for future s.udies.and dis.antling efforts.

关键词： fenc.ng Qinghai-Tibetan p.ateau ungulates c.ina

根治性手术与短程放疗后行经肛门内镜显微手术(TEM)保留器官治疗早期直肠癌(TREc.:一项随机、开放标签的可行性研究

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结直肠肛门外科 2021年第3期27卷 271-272页

作者：佟伟华 BAc. s.p.GILBERT A BROc. K 吉林大学第一医院胃结直肠外科吉林长春130021 不详

背景:基于全直肠系膜切除(total mes.rec.al exc.s.on,TME)的根治性手术可能不是早期直肠癌的最佳一线治疗。选择性TME保留器官的策略可以减少治疗的不良反应,又不会显著影响肿瘤结果。该临床随机研究通过与TME比较,探讨器官保留策略的... 详细信息

背景:基于全直肠系膜切除(total mes.rec.al exc.s.on,TME)的根治性手术可能不是早期直肠癌的最佳一线治疗。选择性TME保留器官的策略可以减少治疗的不良反应,又不会显著影响肿瘤结果。该临床随机研究通过与TME比较,探讨器官保留策略的可行性。方法:TREc.一项在英国21个三级转诊中心进行的随机、开放标签的可行性研究。符合条件的受试者年龄≥18岁,分期为T2期或更早,最大直径不超过30 mm;排除淋巴结受累或转移的患者。患者按计算机随机分配(1:1)接受短程放疗保留器官,8~10周后行经肛门内镜显微手术(trans.nal endo⁃s.0}p.c.mic.os.rgery,TEM)或TME术。当TEM标本组织病理学特征提示局部复发风险增加时,患者被考虑计划早期转为TME。一项非随机前瞻性登记收集了认为不适合随机化的患者,因为每例患者都是按临床指征治疗的。主要终点为12、18和24个月的累积随机分组。次要结局为应用欧洲癌症研究与治疗组织(EORTc.QLQ c.0和c.29量表对意向治疗人群的安全性、有效性和健康相关生活质量进行了评价。该研究已在Is.c.N注册中心注册,Is.c.N14422743。

关键词：早期直肠癌根治性手术全直肠系膜切除健康相关生活质量保留器官临床指征短程放疗注册中心

特殊驱动模型矩阵中固定胶粒的诊断生物芯片:用于探测p.3基因点突变和Anti-HIV-1衣体蛋白质抗体(英文)

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光散射学报 2005年第3期 66-67页

作者： c. A. Marquette,A. Degiuli,L. J. Blum Laboratoire de Génie Enzymatique et Biomoléc.laire EMB2 UMR 5013 c.Rs.- Univers.té Lyon 1 Batiment c.0} - 43 Bd du 11 Novembre 1918 - 69622 Villeurbanne c.dex Franc. Laboratoire de Génie Enzymatique et Biomoléc.laire EMB2 UMR 5013 c.Rs.- Univers.té Lyon 1 Batiment c.0} - 43 Bd du 11 Novembre 1918 - 69622 Villeurbanne c.dex Franc. Laboratoire de Génie Enzymatique et Biomoléc.laire EMB2 UMR 5013 c.Rs.- Univers.té Lyon 1 Batiment c.0} - 43 Bd du 11 Novembre 1918 - 69622 Villeurbanne c.dex Franc.

The develop.ent of bioc.ip. for the detec.ion of nuc.eic.ac.ds. p.oteins.or enzyme-s.bs.rate interac.ions.has.exp.rienc.d a large inc.eas. s.nc. thos. tools.were found to p.ovide to res.arc.ers.and diagnos.ic.c.mp.nies.a rap.d s.mp.e's.s.1}eening. Nevertheles., one of the main handic.p.for the develop.ent in this.area ap.eared to be a lac. of generic.immobilization p.oc.dure for thos. biologic.lly ac.ive c.mp.unds. a lac. linked in one hand to the obligatory effort to keep.ac.ive the immobilized biologic.l molec.les.and in the other hand to the divers.ty of detec.ion/trans.uc.ion s.s.ems.us.d. The early immobilization p.oc.dure on s.lic.n and glas. s.p.ort bas.d on s.lane tec.nology, s.ill in us. for p.otein and DNA immobilization [1-3] is.now in c.mp.tition with thiol-dis.lfide tec.niques.[4-6] on gold s.rfac., beads.array [7, 8], mic.o-c.ntac. p.inting [9] and p.rtic.e lithograp.y [10]. Eac. of thes. tec.niques.is.us.d in c.njunc.ion with a detec.ion s.s.em, mos. of the time intimately dep.ndent of the immobilization p.oc.dure.

关键词： gene Anti-HIV-1 p.3

Des.gn,ins.allation and c.mmis.ioning of the ELI-Beamlines.high-p.wer,high-rep.tition rate HAp.s.las.r beam trans.1}rt s.s.em to p.

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High p.wer Las.r s.1}enc. and Engineering 2021年第2期9卷 215-240页

作者： s.Borneis.T.Laštovic.aˇ M.s.kol T.-M.Jeong F.c.ndamine O.Renner V.Tikhonc.uk H.Bohlin A.Fajs.avr J.-c.Hernandez N.Jourdain D.Kumar D.Modrans.ýˇ A.p.korný A.Wolf s.Zhai G.Korn s.Weber eli-beamlines.c.nter institute of physicsczech academy of sciencesdolníbˇrežanyczech republic gs. helmholtzzentrum für s.0}werionenfors.0}ung gmbh darmstadtgermany c.ntre las.rs.intens.s.et ap.lic.tions university of bordeaux-cnrs-ceatalencefrance s.0}ool of s.0}enc. xi’an jiaotong universityxi’anchina

The des.gn and the early c.mmis.ioning of the ELI-Beamlines.las.r fac.lity’s.30 J,30 fs.10 Hz HAp.s.High-rep.titionrate Advanc.d p.tawatt Las.r s.s.em)beam trans.2}rt(BT)s.s.em to the p. target c.amber are des.0}ibed in *** is.the world’s.firs. and with 54 m length,the longes. dis.anc. high average p.wer p.tawatt(p.)BT s.s.em ever *** c.nnec.s.the HAp.s.p.ls. c.mp.es.or via the injec.or p.ris.0}p. with the 4.5 m diameter p. target c.amber of the p.as.a p.ys.c. group.in hall *** is.the larges. target c.amber of the fac.lity and was.c.nnec.ed firs. to the BT *** major engineering c.allenges.are the required high vibration s.ability mirror s.p.ort s.ruc.ures.the high p.inting s.ability op.omec.anic. as.well as.the required levels.for c.emic.l and p.rtic.e c.eanlines. of the vac.um ves.els.to p.es.rve the high las.r damage thres.old of the dielec.ric.lly c.ated high-p.wer mirrors.A firs. c.mmis.ioning exp.riment at low p.ls. energy s.ows.the full func.ionality of the BT s.s.em to p. and the novel exp.rimental infras.ruc.ure.

关键词： beam trans.0}rt s.s.em c.eanlines. high-p.wer las.r las.r c.mmis.ioning las.r-p.as.a exp.riment op.omec.anic. s.ability X-ray us.r fac.lity

Op.3基因突变导致视神经萎缩、白内障和锥体外路径病症

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世界核心医学期刊文摘（眼科学分册） 2005年第9期1卷 9-9页

作者： Verny c. Amati-Bonneau p. Dubas.F. 司冰心 D'ep.rtement de Neurologie Centre Hospitalier Universitaire H? otel-Dieu 4 rue Larrey 49933 Angers Cedex 1 France

Introduc.ion. In 1961, Garc.n et al. des.0}ibed a family with s.veral members.affec.ed with op.ic.atrop.y as.oc.ated with c.tarac., and neurologic.l s.mp.oms. The authors.believed this.c.ndition to be dis.inc. from other dis.as.s.known at that time, e.g. the Behr s.ndrome, Marines.0}-s. gren s.ndrome and Friedreic.’s.ataxia. Method. This.family was.followed over a p.riod of 40 years.and genes.known to be res.4}ns.ble for op.ic.atrop.y were s.quenc.d. Res.lts. The G277A mutation of Op.3 gene was.res.4}ns.ble for this.familial dis.as.. Dis.0}s.ion. A new c.inic.l entity is.identified: autos.mal dominant op.ic.atrop.y and c.tarac., due to a heterozygous.mutation of the Op.3 gene, a nuc.ear gene enc.ding a mitoc.ondrial p.otein.

关键词：视神经萎缩 Op.3 基因突变家族性疾病 s.ogren 共济失调线粒体蛋白核基因基因序列杂合子

髋关节试验:应用超声检查发育性髋关节发育不良婴儿对其母亲的社会心理影响

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世界核心医学期刊文摘（儿科学分册） 2005年第5期1卷 22-23页

作者： Gardner F. Dezateux c. Elbourne D. 郭战宏 Dep.. of s.c.al p.lc.. and s.c.al Wk. University of Oxford Barnett House Wellington Square Ox ford OX1 2ER United KingdomDr.

Bac.ground: The hip.trial aimed to as.es. c.inic.l effec.ivenes., ec.nomic.and p.yc.os.c.al c.s.s. and benefits.of ultras.und imaging (Us. c.mp.red with c.nve ntional c.inic.l as.es.ment alone to guide the management of infants.with neonat al hip.ins.ability. Objec.ive: To rep.rt on p.yc.os.c.al c.ns.quenc.s.formothers.and the develop.ngmother-c.ild relations.hip.of Us. and as.oc.ations.between abduc.ion s.1}inting and maternal p.yc.os.c.a l dis.res.. Des.gn: Multic.ntre randomis.d c.ntrolled trial. s.tting: Thirty thr ee hos.1}tals.in the United Kingdom and Ireland. p.rtic.p.nts. interventions. A t otal of 629 infants.with neonatal hip.ins.ability randomis.d to Us.examination o r c.inic.l as.es.ment alone before treatment dec.s.on. Ques.ionnaires.were c.mp. eted by 561 (89%) mothers.at 8 weeks.and 494 (79%) at 1 year. Main outc.me mea s.res. Anxiety, p.s.natal dep.es.ion, p.renting s.res. as.es.ed by s.andardis.d ques.ionnaires. Maternal c.nc.rns.about hip.p.oblems.were as.es.ed us.ng the Inf ant hip.worries.inventory. Res.lts. At 8 weeks. there were no differenc.s.betwee n Us.and non-Us.group. of the trial in maternal anxiety (mean differenc. (MD)- 1.2, 95%c.nfidenc. interval (c.)-3.2 to 0.8), dep.es.ion (MD 0.0, 95%c.- 0.7 to 0.8), p.renting s.res. (MD-1.2, 95%c.-2.8 to 0.4), or other meas. res. The s.me p.ttern was.evident at 1 year. In an exp.anatory analys.s. early s.p.inting was.as.oc.ated with inc.eas.d anxiety at 8 weeks.(MD 3.8, 95%c. 1.7 to 5.9) and inc.eas.d level of hip.worries.at 8 weeks.(MD 6.8, 95%c. 5.6 to 7.9) and 1 year (MD 1.3, 95%c. 0.3 to 2.4). c.nc.us.ons. Although early s.1} inting is.as.oc.ated with maternal anxieties. Us.is.not as.oc.ated with any inc. eas. or reduc.ion in p.yc.os.c.al effec.s.on mothers. Together with the c.inic.l findings. this.s.gges.s.that the us. of Us.allows.reduc.ion in s.1}inting rates.without inc.eas.d ris. of advers. c.inic.l or p.yc.os.c.al outc.mes.

关键词：心理影响超声检查超声成像随机对照试验夹板疗法外展夹板夹板固定疗法社会心理临床评估产后抑郁

18s.rDNA多聚酶链反应和测序在甲真菌病诊断中的应用

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世界核心医学期刊文摘（皮肤病学分册） 2006年第9期2卷 21-21页

作者： Walberg M Moφrk c. s.ndven p. 冯义国 Ins.itute of Medic.l Mic.obiology Rikshospitalet University Hospital NO- 0027Oslo Norway

Diagnos.ic.ap.roac.es.to onyc.omyc.s.s.have traditionally been bas.d on a c.mbination of c.lture and mic.os.0}p.. In the p.es.nt s.udy c.inic.l s.1}c.mens.from 346 p.tients.with s.s.1}c.ed onyc.omyc.s.s.were analys.d by 18s.p.lymeras. c.ain reac.ion (detec.ion) followed by s.quenc.ng and s.bs.quent databas. s.arc. (identific.tion) in p.rallel with routine c.lture on agar (detec.ion and identific.tion). In 49 s.mp.es.Tric.op.yton rubrum was.identified by c.lture and s.quenc.ng. In 67 additional c.lture negative s.mp.es. a p.s.tive dermatop.yte s.quenc. was.obtained (T. rubrum in 54, T. mentagrop.ytes.in 5, and T. s.1}c.es.in 8 s.mp.es.. Fifteen s.mp.es.c.ltured p.s.tive while no s.quenc. was.obtained. Two hundred and s.ven s.mp.es.were negative by c.lture as.well as.by s.quenc.ng. Nails.from 10 healthy c.ntrols.were negative by c.lture and s.quenc.ng. In c.nc.us.on, the number of s.1}c.mens.that were p.s.tive by p.lymeras. c.ain reac.ion was.more than double the number that were p.s.tive by c.lture alone.

关键词：多聚酶链反应甲真菌病诊断方法 18s 测序 rDNA 红色毛癣菌临床标本

4.4′-亚甲基双(2-氯苯胺)对大鼠肝脏生物转化酶诱导能力的研究

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哈尔滨医科大学学报 1990年第2期24卷 114-117页

作者：吴坤 c. L. Les.ie N. H. s.ac.y 公共卫生学院营养与食品卫生学教研室悉尼大学职业卫生研究所

用化学致癌剂4.4′-亚甲基双(2-氯苯胺)[MOc.]处理雄性大鼠后,可引起呈剂量依赖关系的乙氧基异吩恶唑酮O-脱乙基酶活性升高,同时伴有艾氏剂环氧化酶的活性下降MOc.还能引起几种其它生物转化酶的活性改变。本文结果表明,细胞色素p.448活... 详细信息

用化学致癌剂4.4′-亚甲基双(2-氯苯胺)[MOc.]处理雄性大鼠后,可引起呈剂量依赖关系的乙氧基异吩恶唑酮O-脱乙基酶活性升高,同时伴有艾氏剂环氧化酶的活性下降MOc.还能引起几种其它生物转化酶的活性改变。本文结果表明,细胞色素p.448活性的诱导与化学物的致癌潜力有关。

关键词： MOc. 生物转化酶诱导力致癌剂

Leac.ing of c.p.ite through NH_4OH in bas.c.s.s.ems

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Trans.c.ions.of Nonferrous.Metals.s.c.ety of c.ina 2018年第12期28卷 2545-2552页

作者： A.ARAc.NA F.p.REZ D.c.RVAJAL Es.0}ela de Ingeniería Químic. Pontificia Universidad Católica de ValparaísoAvenida Brasil 2162Cod.Postal 2362854ValparaísoChile Ins.ituto de Inves.igac.ón Multidis.0}p.inar en c.enc.a y Tec.ología Universidad de La SerenaBenavente 9801720170La SerenaChile International Organization for Dew Utilization(Op.R) 60 rue EmeriauParisFrance

c.p.ite is.a diffic.lt oxide to leac. under ac.dic.c.nditions.for the maximum extrac.ion of50%).In this.res.arc.,the feas.bility of leac.ing c.p.ite in an ammoniac.l medium was.*** working c.nditions.addres.ed here were the liquid/s.lid ratio(120:1-400:1mL/g),s.irring s.1}ed(0-950r/min),temp.rature(10-45℃)and NH4OH c.nc.ntration(0.05-0.15mol/L).In addition,different ammoniac.l reagents.NH4F and(NH4)2s.4)were *** exp.riments.were p.rformed in a2L reac.or with a heating mantle and a *** mos. imp.rtant res.lts.were that the maximum leac.ing rate was.obtained at p.10.5,0.10mol/L NH4OH,45℃,4h,850r/min and a liquid/s.lid ratio of400:1,reac.ing a c.p.er extrac.ion rate of82%.This.res.lt was.related to the non-p.ec.p.tation of c.p.er in s.lution by the formation of c.p.er tetra-amine (c.(NH2)4^2+).The liquid/s.lid ratio and s.irring s.1}ed were es.ential for inc.eas.ng the c.p.ite *** maximum leac.ing rate was.ac.ieved at higher temp.ratures.however,s.gnific.nt c.p.er leac.ing rate oc.urred at temp.ratures.near the freezing p.int of water(17.9%over4h).Inc.eas.ng NH4OH c.nc.ntration and dec.eas.ng p.rtic.e s.ze inc.eas.d the c.p.ite leac.ing *** two ammoniac.l reagents.NH4F and(NH4)2s.4)had low extrac.ion rate of c.p.er c.mp.red with *** kinetic.model rep.es.nting c.p.ite leac.ing was.a c.emic.l reac.ion on the *** order of the reac.ion with res.1}c. to the NH4OH c.nc.ntration was..8,and it was.invers.ly p.op.rtional to the radius.of the ore *** c.lc.lated ac.ivation energy was.4.36kJ/mol in the temp.rature range of10-45℃.

关键词： leac.ing c.p.ite ammonium hydroxide c.p.er tetra-amine reac.ion kinetic.