检索结果-南通市图书馆

Insulin resistance in H pylori infection and its association with oxidative stress

World Journal of Gastroenterology 2006年第42期12卷 6865-6868页

作者： Mehmet Aslan Mehmet Horoz Yasar Nazligul Cengiz Bolukbas F Fusun Bolukbas Sahbettin Selek Hakim Celik ozcan erel Department of Internal Medicine Faculty of Medicine Harran University Sanliurfa Turkey Department of Gastroenterology Faculty of Medicine Harran University Sanliurfa Turkey Department of Clinical Biochemistry Faculty of Medicine Harran University Sanliurfa Turkey

AIM: To determine the insulin resistance (IR) and oxidative status in H pylori infection and to find out if there is any relationship between these parameters and insulin resistance. METHODS: Fifty-five H pylori positive and 48 H pylori negative patients were enrolled. The homeostasis model assessment (HOMA) was used to assess insulin resistance. Serum total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined in all subjects. RESULTS: The total antioxidant capacity was significantly lower in H pylori positive group than in H pylori negative group (1.36 ± 0.33 and 1.70 ± 0.50, respectively; P < 0.001), while the total oxidant status and oxidative stress index were significantly higher in H pylori positive group than in H pylori negative group (6.79 ± 3.40 and 5.08 ± 0.95, and 5.42 ± 3.40 and 3.10 ± 0.92, respectively; P < 0.001). Insulin resistance was significantly higher in H pylori positive group than in H pylori negative group (6.92 ± 3.86 and 3.61 ± 1.67, res- pectively; P < 0.001). Insulin resistance was found to be significantly correlated with total antioxidant capacity (r = -0.251, P < 0.05), total oxidant status (r = 0.365, P < 0.05), and oxidative stress index (r = 0.267, P < 0.05). CONCLUSION: Insulin resistance seems to be associated with increased oxidative stress in H pylori infection. Further studies are needed to clarify the mechanisms underlying this association and elucidate the effectof adding antioxidant vitamins to H pylori eradication therapy on insulin resistance during H pylori infection.

关键词： Hpylori Insulin resistance Total antioxidant capacity Total oxidant status Oxidative stress index

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thiol-Disulphide Balance:Could Be a New Marker for Thyroid Cancer?

引用

Journal of Cancer Therapy 2018年第8期9卷 598-604页

作者： Ayse Ozdemir ozcan erel Department of Biochemistry Usak Training and Research HospitalUsak UniversityUsakTurkey Department of Biochemistry Ankara Atatürk Training and Research HospitalYildirim Beyazit UniversityAnkaraTurkey

Objectives. Cancer is a very widespread disorder known in world wide since long, but its biochemical features remain unclear. Thyroid carcinomas are the most common endocrine cancer and its frequency continues to escalate. There is evidence that the serum concentration of TSH is an unreliant predictor for the diagnosis of thyroid cancer. The formation of the plasma thiol pool from low and large molecular weight proteins suggests that thiol/disulfide balance is important in cancerous cases. The aim of this study was to investigate an oxidative stress marker (thiol/disulphide homeostasis) and IMA (Ischemia modified albumin), Albumin, CEA (Carcinoembryonic antigen), TSH (Thyroid stimulate hormone), thyroxine (T4), free thyroxine (FT4), triiodothyronine (T3) and free triiodothyronine (FT3) in patients with thyroid cancer and compare the results with healthy controls for the first time in literature. Materials-Methods: A total of 43 participants including 23 patients with thyroid cancer and 20 healthy individuals were included in the study. Serum levels of TSH, T4, FT4, T3 and FT3 have been measured during treatment and follow-up of patients with thyroid carcinoma. Serum levels of TSH, T4, FT4, T3 and FT3, IMA, Albumin, CEA, Native thiol (-SH), disulfide (-S-S) and total thiol (TT) as well as disulphide/native thiol and disulphide/total thiol ratios were compared between the groups. Native thiol, disulfide and total thiol concentrations were measured with a novel automated method (Roche, cobas 501, Mannheim, Germany). Results and conclusion: This paper discusses an oxidative stress marker (thiol/disulphide homeostasis) and tumor markers IMA, Albumin, CEA, TSH, T4, FT4, T3 and FT3 in patients with thyroid cancer and compare the results with healthy controls. Mean age at participant was 41.73 years for thyroid cancer patients (21 females/2 males). A control group of 20 participants was included the study (19 females/1 male, mean age 51.75).

关键词： Disulphide Thiol Tumor Marker Thyroid Cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dynamic Thiol-Disulphide Homeostasis in Patients with Multiple Sclerosis

引用

World Journal of Neuroscience 2016年第3期6卷 214-219页

作者： Gonul Vural Sadiye Gumusyayla Hesna Bektas Orhan Deniz Merve Ergin ozcan erel Department of Neurology School of Medicine Yildirim Beyaz?t University Ankara Turkey Department of Neurology Atatürk Training and Research Hospital Ankara Turkey Department of Clinical Biochemistry Atatürk Training and Research Hospital Ankara Turkey Department of Clinical Biochemistry School of Medicine Yildirim Beyaz?t University Ankara Turkey

Objective: The aim of this study was to evaluate thiol-disulphide homeostasis in patients with Multiple Sclerosis (MS) during attack and remission. Design and Methods: A total of 82 patients admitted to our clinic were divided into 2 groups according to whether they are having an attack or not. Peripheral blood samples were taken from all patients and their native thiol, disulphide and total thiol concentrations were measured by a newly developed automated method. In addition, their disulphide/native thiol, disulphide/total thiol and native thiol/total thiol ratios were calculated. Results: The average disulphide values, disulphide/native thiol and disulphide/total thiol ratios of the patients with MS who were having an attack were found to be significantly higher compared to those in remission (p = 0.001, p = 0.001, p = 0.001, respectively). Conclusion: Our results have shown that thiol-disulphide balance was shifted to the oxidative area during the relapse. These homeostasis parameters, which can be easily measured by this newly developed method at low costs, may be important in terms of showing the disease activity and presenting the underlying mechanisms of the disease.

关键词： Multiple Sclerosis Relapse Oxidative Stress Thiol-Disulphide Homeostasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thiol/disulphide homeostasis in celiac disease

引用

World Journal of Gastrointestinal Pharmacology and Therapeutics 2017年第2期8卷 120-126页

作者： Mustafa Kaplan Ihsan Ates Mahmut Yuksel Yasemin Ozderin Ozin Murat Alisik ozcan erel Ertugrul Kayacetin Department of Gastroenterology Turkey Yuksek Ihtisas Training and Research Hospital Department of Internal Medicine Ankara Numune Training and Research Hospital Department of Biochemistry Yildirim Beyazit University Medical Faculty

AIM To determine dynamic thiol/disulphide homeostasis in celiac disease and to examine the associate with celiac autoantibodies and gluten-free *** Seventy three patients with celiac disease and 73 healthy volunteers were enrolled in the study. In both groups, thiol/disulphide homeostasis was examined with a new colorimetric method recently developed by erel and Neselioglu. RESULTS In patients with celiac disease, native thiol(P = 0.027) and total thiol(P = 0.031) levels were lower, while disulphide(P < 0.001) level, disulphide/native thiol(P < 0.001) and disulphide/total thiol(P < 0.001) ratios were higher compared to the control group. In patients who do not comply with a gluten-free diet, disulphide/native thiol ratio was found higher compared to the patients who comply with the diet(P < 0.001). In patients withany autoantibody-positive, disulphide/native thiol ratio was observed higher compared to the patients with autoantibody-negative(P < 0.05). It is found that there is a negative correlation between celiac autoantibodies, and native thiol, total thiol levels and native thiol/total thiol ratio, while a positive correlation is observed between disulphide, disulphide/native thiol and disulphide/total thiol *** This study is first in the literature which found that the patients with celiac disease the dynamic thiol/disulphide balance shifts through disulphide form compared to the control group.

关键词： Anti-gliadin antibodies Anti-tissue transglutaminase antibody Gluten-free diet Oxidative stress Thiol oxidation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sesame response to nitrogen management under contrasting water availabilities

引用

Oil Crop Science 2022年第4期7卷 166-173页

作者： Elnatan Golan Zvi Peleg Zipora Tietel Ran erel Gilat Research Center Agricultural Research OrganizationIsrael The Robert H.Smith Faculty of Agriculture Food and EnvironmentThe Hebrew University of JerusalemIsrael

Sesame is mainly cultivated under traditional,low-input *** breeding developments promoted the modernization and mechanization of sesame ***,only a few articles have been published concerning fertilization requirements for both modern and traditional *** field trials at two locations,we determined the response of irrigated sesame to nitrogen(N).Three promising sesame lines were tested combining two irrigation levels with four N *** a high irrigation level,N had a significant effect on growth,branching,and consequently,seed yield exceeding two-ton ha^(-1).A high N doze was accompanied by a decrease in the photosynthetic rate and leaf water *** δ^(13)C confirmed lower stomatal conductance under high N *** deficit irrigation,the N level had a minor effect on the monitored parameters,indicating N fertilization was not *** oil content was negatively correlated with seed N *** results question the necessity of N application when water is limited,as N fertilization promotes vigorous development that rapidly depletes soil ***,water availability should be considered when developing an N management *** high-yielding agro-systems,roughly 80–120 kg ha^(-1)N is required for optimal yield,bearing in mind the negative association between seed-N and oil content.

关键词： Nitrogen-use efficiency Seed-oil Irrigation Fertigation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of drip irrigation and cropping on soil salinity,ionic composition and waxy corn production in a severely saline and calcareous and gypsiferous soil

引用

International Journal of Agricultural and Biological Engineering 2023年第5期16卷 142-154页

作者： Junli Tan Yaohu Kang Yanping Jiao Shuqin Wan Xina Wang Juncang Tian Ran erel Alon Ben-Gal School of Civil and Hydraulic Engineering Ningxia UniversityYinchuan 750021China Key Laboratory of Water Cycle and Related and Land Surface Processes Institute of Geographical Sciences and Natural Resource ResearchChinese Academy of SciencesBeijing 100101China Hebei Provincial Academy of Water Resources Shijiazhuang 050051China Institute of Soil Water and Environmental SciencesAgricultural Research OrganizationGilat Research Center85280 moblie post NegevIsrael

Drip technologies have been suggested as practical for irrigation under conditions of high salinity and for reclamation of saline *** irrigation triggered by soil water potential thresholds was applied to both reclaim a severely saline calcareous gypsiferous soil and irrigate a waxy corn crop(Zea mays *** Kulesh).However,there is a lack of knowledge on the sustainability of reclamation of saline soils with drip irrigation and the changes in soil salinity and salt ion composition during the amelioration ***,effects on soil salinity,its ionic composition,and on crop growth and yields were evaluated in an experiment conducted in the Yinchuan Plain,northwest *** included fields in their first to fourth years of the drip irrigation reclamation-cropping scheme and adjacent native,non-cropped or irrigated salinesodic land as *** of waxy corn increased and days of growth to maturity decreased as a function of time and reclamation *** improvement in crop performance could be largely credited to the reduction of soil salinity and changes in salt composition under the drip-irrigated reclamation *** drip irrigation regime created a region of low salinity proximal to the emitters conducive to germination and plant *** ions for crop growth such as Na+and Cl^(-)were reduced while Ca2+and Mg2+concentration increased,especially in the upper 40 cm of *** only a single season of drip-irrigated waxy corn production,both Cl-SO_(4)^(2-)ratios and sodium adsorption ratio(SAR)decreased *** results suggested that drip irrigation is an effective technology for reclamation of severely saline-affected soils,such as those widely distributed over the Ningxia Plain in China and that this or similar reclamation strategy could be appropriate for reclamation of other hard to manage calcareous and gypsiferous soils.

关键词： soil salinity calcareous gypsiferous ion composition leaching salt transport

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of honey on bacterial translocation and intestinal morphology in obstructive jaundice

引用

World Journal of Gastroenterology 2008年第21期14卷 3410-3415页

作者： Cem Gencay Kemal Kismet Bulent Kilicoglu Serap erel Mehmet Ali Akkus Sibel Serin Kilicoglu Sabahattin Muratoglu Asli Elif Sunay Esra Erdemli Ankara Training and Research Hospital4th General Surgery Department Ankara 06340Turkey Ufuk University School of Medicine Department of Histology and EmbryologyAnkara 06800Turkey Ankara Training and Research Hospital Microbiology Department Ankara 06340Turkey Food Engineer Balparmak Pazarlama34760CekmekoyIstanbul Turkey Ankara University School of Medicine Department of Histology and Embryology4Ankara 06370Turkey

AIM:To evaluate the effects of honey on bacterial translocation and intestinal villus histopathology in experimental obstructive ***:Thirty Wistar-Albino rats were randomly divided into three groups each including 10 animals:group Ⅰ,sham-operated;group Ⅱ,ligation and section of the common bile duct(BDL);group Ⅲ,bile duct ligation followed by oral supplementation of honey(BDL+honey) 10 g/kg per ***,blood,spleen,mesenteric lymph nodes,and ileal samples were taken for microbiological,light and transmission electrone microscopic ***:Although the number of villi per centimeter and the height of the mucosa were higher in sham group,there was no statistically significant difference between sham and BDL + honey groups(P>0.05).On the other hand,there was a statistically significant difference between BDL group and other groups(P0.05).BDL group had significantly higher rates of bacterial translocation as compared with sham and honey *** translocation was predominantly detected in mesenteric lymph ***:Supplementation of honey in presence of obstructive jaundice ameliorates bacterial translocation and improves ileal morphology.

关键词： Honey Obstructive jaundice Intestinalvillus atrophy Bacterial translocation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of honey as a scolicidal agent on the hepatobiliary system

引用

World Journal of Gastroenterology 2008年第13期14卷 2085-2088页

作者： Bulent Kilicoglu Kemal Kismet Sibel Serin Kilicoglu Serap erel Omur Gencay Kadriye Sorkun Esra Erdemli Okan Akhan Mehmet Ali Akkus Iskender Sayek Department of General Surgery Ankara Training and Research Hospital Ankara 06340 Turkey Department of Histology-Embryology Ufuk University Ankara 06340 Turkey Department of Biology Faculty of Science Hacettepe University Ankara 06340 Turkey Department of Histology-Embryology Ankara University Ankara 06340 Turkey Department of Radiology Hacettepe University Ankara 06340 Turkey Department of General Surgery Hacettepe University Ankara 06340 Turkey

AIM： To examine the effects of 10% diluted honey, which has been shown to be scolicidal, on the liver and biliary system and determine whether it could be used as a scolicidal agent in the presence of biliary-cystic communication. METHODS： Thirty Wistar-Albino rats were divided into two groups. Honey with 10% dilution in the study group and 0.9% saline （NaCI） in the control group were injected into the common bile ducts of rats through a 3-mm duodenotomy. The animals were sacrificed 6 mo alter the procedure. Histopathological, biochemical, and radiological examinations were performed for evaluation of side effects. RESULTS： At the end of the sixth month, liver function tests were found to be normal in both groups. The tissue samples of liver and ductus choledochus of the honey group showed no histomorphologic difference from the control group. No stricture on the biliary tree was detected on the retrograde cholangiograms. CONCLUSION： According to these results, we concluded that 10% diluted honey could be used as scolicidal agent safely in the presence of biliary-cystic communication.

关键词： Scolocidal agent Honey Hepatobiliary system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Propolis reduces bacterial translocation and intestinal villus atrophy in experimental obstructive jaundice

引用

World Journal of Gastroenterology 2007年第39期13卷 5226-5231页

作者： Mehmet Zafer Sabuncuoglu Kemal Kismet Sibel Serin Kilicoglu Bulent Kilicoglu Serap erel Sabahattin Muratoglu Asli Elif Sunay Esra Erdemli Mehmet Ali Akkus 4th General Surgery Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Department of Histology and EmbriologyUfuk University School of Medicine Ankara 06520 Turkey Microbiology Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Food Engineer Balparmak Pazarlama Cekmekoy 34760 Istanbul Turkey Department of Histology and Embriology Ankara University School of Medicine 06100 Ankara Turkey

AIM： To investigate the effects of propolis on bacterial translocation and ultrastructure of intestinal morphology in experimental obstructive jaundice. METHODS： Thirty Wistar-Albino male rats were randomly divided into three groups, each including 10 animals： group Ⅰ, sham-operated; group Ⅱ, ligation and division of the common bile duct （BDL）; group Ⅲ, BDL followed by oral supplementation of propolis 100 mg/kg per day. Liver, blood, spleen, mesenteric lymph nodes, and ileal samples were taken for microbiological, light and transmission electron microscopic examination on postoperative 7^th d after sacrification. RESULTS： The mean number of villi per centimeter and mean mucosal height of the propolis group were significantly different in the BDL group （P = 0.001 and 0.012, respectively）. The electron microscopic changes were also different between these groups. Sham and BDL＋propolis groups had similar incidence of bacterial translocation （BT）. The BDL group had significantly higher rates of BT as compared with sham and BDL ＋ propolis groups. BT was predominantly detected in MLNs and the most commonly isolated bacteria was Escherichia coil CONCLUSION： Propolis showed a significant protective effect on ileal mucosa and reduced bacterial translocation in the experimental obstructive jaundice model. Further studies should be carried out to explain the mechanisms of these effects,

关键词： Obstructive jaundice Bacterial translocation Ileal morphology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于输入-输出平衡的施磷方法可实现作物高产和磷肥高效——以新疆水肥一体化棉花体系为例

引用

土壤学报 2023年第5期60卷 1480-1492页

作者：彭懿杨国江国秀丽王晓凤 erel Ran 冯固中国农业大学资源与环境学院北京100193 新疆农垦科学院农田水利与土壤肥料研究所新疆石河子832000 石河子大学农学院新疆石河子832003 和布克赛尔蒙古自治县农业技术推广站新疆塔城834400 以色列农业部吉拉特农业研究中心以色列7505101

探讨了通过目标产量需磷量确定磷肥用量并在棉花生长早期集中施用的磷肥管理方法以维持适宜的土壤供磷强度、实现作物高产和磷肥高效利用目标的可行性,为磷肥减施增效提供依据。在新疆石河子选择中等供磷强度的农田(有效磷23.6 mg·kg^(... 详细信息

探讨了通过目标产量需磷量确定磷肥用量并在棉花生长早期集中施用的磷肥管理方法以维持适宜的土壤供磷强度、实现作物高产和磷肥高效利用目标的可行性,为磷肥减施增效提供依据。在新疆石河子选择中等供磷强度的农田(有效磷23.6 mg·kg^(–1)),以覆膜水肥一体化棉花(Gossypium hirsutum)种植体系为对象,根据该区域2.7 t·hm^(–2)皮棉产量的需磷量确定试验的磷肥用量(52.4 kg·hm^(–2),以P计),开展了两年田间试验。试验选用三种不同性质的水溶性磷肥,设置不施磷肥(CK)、滴施磷酸一铵(MAP)、滴施磷酸脲(UP)和滴施聚磷酸铵(APP)4个处理。通过测定不同处理棉花的产量与磷吸收量,计算磷肥偏生产力(PFP)、磷肥农学效率(AEP)、磷肥当季利用率(PUE)与当季磷肥回收率(即作物吸磷量与磷肥施用量的比值);通过棉花不同生育期分层取样,分析了不同磷肥品种处理引起的土壤有效磷供应强度和无机磷形态组成的变化,以期阐明不同磷肥的空间有效性与棉花生长需求的匹配程度。研究结果表明:(1)施磷处理两年的皮棉产量平均为2.73 t·hm^(–2),达到了高产水平,MAP、UP和APP处理分别较CK增产21%、25%和11%;(2)施磷处理的磷盈余为2.2~4.8 kg·hm^(–2),磷肥当季利用率平均为24%,当季磷肥回收率为91%~96%;(3)磷肥在棉花蕾期和花铃期集中滴施,其垂直移动距离可达到20 cm土层,能保证棉花生育期内的土壤供磷强度。与CK相比,施磷处理根区0~5 cm、5~10 cm、10~20 cm土层的有效磷分别提高了94%~302%、104%~144%和42%~67%。综上所述,将土壤有效磷供应强度维持在农学阈值附近、根据目标产量需磷量确定磷肥施用量,石灰性土壤上选择强酸性、缓释磷肥于作物生育前期集中施用能够在磷素输入-输出平衡的条件下实现作物高产和磷肥高效。根据平衡法计算的当季磷肥回收率能较好地反映磷肥的实际利用情况。

关键词：产量聚磷酸铵磷酸脲磷肥利用率棉花

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：