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技术经济与管理研究 1997年第3期 21-22页

作者： MayorPhilipW.owen

Non-small bowel lesion detection at small bowel capsule endoscopy: A comprehensive literature review

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World Journal of Clinical Cases 2018年第15期6卷 901-907页

作者： Apostolos Koffas Faidon-Marios Laskaratos owen Epstein Gastroenterology Department University Hospital of Larisa Centre for Gastroenterology Royal Free Hospital

Small bowel capsule endoscopy is a minimally-invasive endoscopic investigation that is often used in clinical practice to investigate overt or occult gastrointestinal(GI) bleeding among other clinical indications. International guidance recommends small bowel capsule endoscopy as a first-line investigation to detect abnormalities in the small bowel, when gastroscopy and colonoscopy fail to identify a cause of GI bleeding. It can diagnose with accuracy abnormalities in the small bowel. However, there has been increasing evidence indicating that small bowel capsule endoscopy may also detect lesions outside the small intestine that are within the reach of conventional endoscopy and have been probably missed during prior endoscopic investigations. Such lesions vary from vascular deformities to malignancy and their detection often alters patient management, leading to further endoscopic and/or surgical interventions. The current study attempts to review all available studies in the literature and summarise their relevant findings.

关键词： Obscure gastrointestinal bleeding Small bowel capsule endoscopy Non-small bowel lesions Overt gastrointestinal bleeding Occult gastrointestinal bleeding Iron deficiency anaemia

Incidence and outcomes of intracerebral haemorrhage with mechanical compression hydrocephalus

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Stroke & Vascular Neurology 2021年第3期6卷 328-336页

作者： Bryce owen Omar Akbik Michel Torbey Herbert Davis Andrew P Carlson School of Medicine University of New Mexico School of MedicineAlbuquerqueNew MexicoUSA Neurosurgery University of New MexicoAlbuquerqueNew MexicoUSA Neurology University of New MexicoAlbuquerqueNew MexicoUSA Division of Epidemiology Biostatisticsand Preventive MedicineUniversity of New MexicoAlbuquerqueNew MexicoUSA

Introduction Intracerebral haemorrhage(ICH)within deep structures adjacent to the third ventricle is associated with worse outcomes when compared with lobar ICH due to the critical role of deep nuclei in normal neurological *** evidence suggests another contributing factor to poor outcome is obstruction of cerebrospinal fluid outflow by clot burden causing mechanical compression of the third *** authors reviewed the incidence and outcomes of mechanical compression ICH in order to identify this high-risk group which may potentially benefit from minimally invasive *** Patients with spontaneous,non-traumatic,supratentorial ICH were identified retrospectively over a 30-month *** imaging was reviewed to assess location of the ICH,volume of the ICH,presence of hydrocephalus requiring external ventricular drain(EVD)placement,and time to clearing of the third *** was then categorised as due to‘primarily intraventricular haemorrhage(IVH)’,‘primarily mechanical compression’or‘mixed’.Functional outcomes at discharge were assessed using the modified Rankin Score(mRS).Results 287 patients met inclusion criteria,of which 39(13.5%)patients developed hydrocephalus that required *** patients had significantly higher mRS at discharge(p≤0.001)when compared with the non-EVD *** location was associated with lower odds of poor outcome compared with thalamic location(OR 0.107-0.560).Mechanical compression hydrocephalus was associated with poor outcome when compared with the primary IVH hydrocephalus subgroup(p=0.037)as well as longer time to clearing of the third ventricle(p=0.006).Conclusions Mechanical obstruction requiring EVD occurs in approximately(21/287)7.3%of all patients with spontaneous supratentorial *** is unknown if the worse morbidity in these subjects is purely related to damage to deep structures surrounding the third ventricle or if secondary damage from hydrocephalus could be mitigated with tar

关键词： hydrocephalus damage primarily

Alpha-1-antitrypsin deficiency resulting in a hitherto unseen presentation of hepatocellular carcinoma:Polycythemia but with normal alpha fetoprotein

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World Journal of Gastroenterology 2006年第30期12卷 4906-4907页

作者： David Ryan owen Ramachandran Sivakumar Eui-Sik Suh Murugiah Seevaratnam Department of Geriatric Medicine Area Q111 Queen Elizabeth Ⅱ Hospital Howlands Welwyn Garden City Hertfordshire AL7 4HQ United Kingdom

Polycythemia is a known paraneopastic manifestation of hepatoma, but only in the presence of alpha-fetopro （AFP）. We present a case of polycythemia in the absence of AFP, and suggest concurrent alpha-1-antitrypsin deficiency as the cause for breaking this rule. We also suggest a reason for the apparent constant conjunction between polycythemia and AFP in hepatoma.

关键词： Hepatoma Polycythemia Alpha 1 anti trypsin Ephrin-A Alpha-fetopro

The significance of clinical practice guidelines on adult varicocele detection and management

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Asian Journal of Andrology 2016年第2期18卷 269-275,J0006,J0007页

作者： Anand Shridharani Ryan C owen Osama O Elkelany Edward D Kim Department of Urology University of Tennessee College of Medicine Chattanooga TN 37403 USA Division of Urology Department of Surgery University of Tennessee Graduate School of Medicine Knoxville TN 37920 USA.

Varicoceles are the most common correctable etiology of male factor infertility. However, the detection and management of varicoceles have not been standardized. This has led to decades of debate regarding the effect of varicocele on male infertility and subsequently whether repair leads to an improved fertility status. The current body of evidence investigating the role of varicocele and varicocelectomy is weak and conflicting. The stance taken by the AUA and ASRM suggests that there is insufficient outcomes data to support evidenced-based guidelines, citing evidence used to provide current recommendations are generally of a low quality level. On the other hand, the EAU Guidelines give a level la of evidence for management of varicoceles that are clinically palpable, associated with subnormal semen analyses and having otherwise unexplained fertility. Besides aiding with clinical varicocele detection and management, clinical practice opinion statements and guidelines aim to direct and strengthen the infrastructure of future studies. We review the current status of opinion statements and guidelines in varicocele and management detection with focus on their application in practice.

关键词： guidelines varicocele varicocele detection varicocele management varicocelectomy

Contextual influences on animal decision-making:Significance for behavior-based wildlife conservation and management

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Integrative Zoology 2017年第1期12卷 32-48页

作者： Megan A.owen Ronald R.SWAISGOOD Daniel T.BLUMSTEIN Institute for Conservation Research San Diego Zoo GlobalSan DiegoCaliforniaUSA Department of Ecology and Evolutionary Biology University of CaliforniaLos AngelesCaliforniaUSA

Survival and successful reproduction require animals to make critical decisions amidst a naturally dynamic environmental and social background(i.e.“context”).However,human activities have pervasively,and rapidly,extended contextual variation into evolutionarily novel territory,potentially rendering evolved animal decision-making mechanisms and strategies *** suggest that explicitly focusing on animal decision-making(ADM),by integrating and applying findings from studies of sensory ecology,cognitive psychology,behavioral economics and eco-evolutionary strategies,may enhance our understanding of,and our ability to predict how,human-driven changes in the environment and population demography will influence animal ***,the decisions animals make involve evolved mechanisms,and behaviors emerge from the combined action of sensory integration,cognitive mechanisms and strategic rules of thumb,and any of these processes may have a disproportionate influence on *** there is extensive literature exploring ADM,it generally reflects a canalized,discipline-specific approach that lacks a unified conceptual *** a result,there has been limited application of ADM theory and research findings into predictive models that can enhance management outcomes,even though it is likely that the relative resilience of species to rapid environmental change is fundamentally a result of how ADM is linked to contextual ***,we focus on how context influences ADM,and highlight ideas and results that may be most applicable to conservation biology.

关键词： animal behavior anthropogenic change context decision-making wildlife management

SWI1 Is Required for Meiotic Chromosome Remodeling Events

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Molecular Plant 2008年第4期1卷 620-633页

作者： Kingsley A. Boateng Xiaohui Yang Fuqui Dong Heather A. owen Christopher A. Makaroff Department of Chemistry and Biochemistry Miami University Oxford OH 45056 USA Present address: Department of Biological Sciences University of Wisconsin-Milwaukee Milwaukee Wl 53211 USA

The Arabidopsis dsy10 mutant was previously identified as being defective in the synapsis of meiotic chromosomes resulting in male and female sterility. We report here the molecular analysis of the mutation and show that it represents a T-DNA insertion in the third exon of the SWll gene. Four mutations have now been identified in SWI1, several of which exhibit different phenotypes. For example, the swil- 1 and dyad mutations only affect meiosis in megasporocytes, while the swil-2 and dsy10 mutations block both male and female meiosis. Furthermore, as part of a detailed cytological characterization of dsy10 meiocytes, we identified several differences during male meiosis between the swil-2 and dys10 mutants, including variations in the formation of axial elements, the distribution of cohesin proteins and the timing of the premature loss of sister chromatid cohesion. We demonstrate that dsy10 represents a complete loss-of-function mutation, while a truncated form of SWll is expressed during meiosis in swil-2 plants. We further show that dys10 meiocytes exhibit alterations in modified histone patterns, including acetylated histone H3 and dimethylated histone H3-Lysine 4.

关键词： Arabidopsis meiosis sister chromatid cohesion chromatin remodeling histone.

THE CONTROL OF POLYMETHACRYLATE MOLECULAR STRUCTURE BY GROUP TRANSFER POLYMERIZATION

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Chinese Journal of Polymer Science 1990年第1期8卷 1-9页

作者： owen W. WEBSTER Central Research and Development Department E. I. Du Pont and CompanyP.O.Box 80328WilmingtonDelaware 19880-0328 USA

INTRODUCTION Group transfer polymerization (GTP) is a method for controlling the structure of acrylic polymers in which reactive chain ends are covalentiy bound to a trimethylsilyl group. In the presence of a catalyst, monomer inserts into these chain ends between the silyl group and the last monomer unit. The process is illustrated by equation (1) for methyl methacrylate. GTP is a living polymerization, i. e., there is little or no chain termination and no chain transfer. A significant advantage of GTP is that it

关键词： PMMA EA GTP rate PBMA THE CONTROL OF POLYMETHACRYLATE MOLECULAR STRUCTURE BY GROUP TRANSFER POLYMERIZATION

Fifty years of finite elements——a solid mechanics perspective

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Theoretical & Applied Mechanics Letters 2012年第5期2卷 1-5页

作者： D.R.J.owen Civil and Computational Engineering Centre Swansea University

The finite element method has been considered as one of the most significant engineering advances of the twentieth century. This computational methodology has made substantial impact on many fields in science and also has profoundly changed engineering design procedures and practice. This paper, mainly froln a solid mechanics perspective, and the Swansea viewpoint in particular, describes very briefly the origin of the methodology, then summaries selected milestones of the technical developments that have taken place over the last fifty years and illustrates their application to some practical engineering problems.

关键词： inite elements isoparametric representation elasto-plasticity finite strain mesh adaptiv ity discrete and multi-fracturing modelling

From pandemic to a new normal:Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model

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Infectious Disease Modelling 2022年第3期7卷 346-363页

作者： Benny Yong Jonathan Hoseana Livia owen Center for Mathematics and Society Department of MathematicsParahyangan Catholic UniversityBandung40141Indonesia

There are five different forms of intervention presently realised by the Indonesian government in an effort to end the COVID-19 pandemic:vaccinations,social restrictions,tracings,testings,and *** this paper,we construct a mathematical model of type SVEIQHR(susceptible-vaccinated-exposed-infected-quarantined-hospitalised-recovered)for the disease's spread in the country,which incorporates as parameters the rates of the above interventions,as well as the vaccine's *** determine the model's equilibria and basic reproduction *** the model,we formulate strategies by which the interventions should be realised in order to optimise their *** results show that,in a disease-free state,when the number of new cases rises,the best strategy is to implement social restrictions,whereas in an endemic state,if a near-lockdown policy is undesirable,carrying out vaccinations is the best strategy;however,efforts should be aimed not primarily towards increasing the vaccination rate,but towards the use of highefficacy vaccines.

关键词： COVID-19 Equilibrium Basic reproduction number Intervention Social restriction Vaccination