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Low Birth Weight and Intermittent Preventive Treatment of Malaria in Pregnant Women in Lomé (Togo) in 2021: A Cross-Sectional Study

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Open Journal of Epidemiology 2024年第1期14卷 31-44页

作者： Roméo Mèdéssè Togan ounoo elom.takassi Fifonsi Gbeasor-Komlanvi Arnold Junior Sadio Rodion Yao Konu Martin Kouame Tchankoni Iwone Oumarou Adama Latame Komla Adoli Dzayissé Yawo Atakouma Didier Koumavi Ekouévi Department of Public Health Faculty of Health Sciences University of Lomé Lomé Togo African Center for Research in Epidemiology and Public Health (CARESP) Lomé Togo Training and Research Center in Public Health University of Lomé Lomé Togo Department of Pediatrics Faculty of Health Sciences University of Lomé Lomé Togo Global Health in the Global South (GHIGS) Team Insem UMR 1219 IRD EMR 271 University of Bordeaux Bordeaux France

Background: Since 2012, the World Health Organization has recommended intermittent preventive treatment with sulfadoxine-pyrimethamine (IPT-SP) to prevent malaria-related complications in pregnant women. Ten years following these recommendations, we conducted this study to estimate the coverage for three doses of IPT-SP (IPT3) as well as the prevalence of low birth weight (LBW), and its associated factors in Lomé (Togo) in 2021. Methods: A cross-sectional study was conducted between January and March 2021. An exhaustive recruitment of women and their newborns was carried out in the maternity wards of the Sylvanus Olympio University Hospital Center. Data from antenatal consultations and clinical data of the newborns were collected. Multivariate logistic regression was carried out to determine factors associated with LBW. Results: A total of 252 mother-child pairs were included in this study. Median age of the mothers was 27 years, IQR [24-31]. More than a third (35.3%) of the mothers were primigravida. IPT3 coverage was 66.7% and 14.7% of newborns had a LBW. The prevalence of LBW was 33.3% [23.3-43.4] in women who had received fewer than 3 doses of IPT-SP and 5.4% [2.0-8.8] in those who had received at least 3 doses of IPT-SP (p Conclusion: Ten years following recommendations of the WHO on IPT-SP, malaria prevention based on IPT-SP is not optimal among pregnant women in Lomé, and the proportion of LBW children remains high. Actions to strengthen the three-dose IPT-SP policy are needed to prevent malaria and its consequences among newborns in Togo.

关键词： Malaria Intermittent Preventive Treatment Low Birth Weight Togo

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Outpatient Management of Sickle Cell Disease: Assessment of 13 Years Follow-Up of Pediatric Patients at the Sylvanus Olympio University Hospital

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Open Journal of Pediatrics 2022年第2期12卷 413-423页

作者： Koffi Mawuse Guedenon Djatougbe Ayaovi Elie Akolly Essohana Padaro ounoo elom.takassi Etsè Akpako Balakibawi Esso Kokou Dzata Adama Dodji Gbadoe Department of Pediatrics CHU Sylvanus Olympio University of Lomé Lomé Togo Department of Hematology CHU Campus University of Lomé LoméTogo University of Maryland Medical Systems/Midtown Campus Baltimore MD USA

Objective: To evaluate thirteen years of ambulatory follow-up of patients with major forms of sickle cell disease. Methods: This was a study of 1055 records of sickle cell patients aged 6 months to 45 years followed between 2006 and 2018. Results: Six hundred and eighty-one (64.5%) homozygous SS, 283 (26.8%) SC, 86 (8.2%) SF, 4 (0.4%) S? thalassemia and 1 (0.1%) SD sickle cell patients were followed. The majority of the patients (97.9%) were living in the capital city of Lomé and its surrounding suburbs. Most children (67.3%) were less than 5-year-old when they were diagnosed with sickle cell disease, and only 21.3% of cases were discovered before the first year birthday of the patients. Osteo-articular vaso occlusive crisis (VOC) was the principal symptom at the onset of the diagnosis, approximately 28.9% of the cases, followed by severe anemia (19%), then hand-foot syndrome in 15.6%. The systematic screening was performed in 5.4%. Twenty-six percent were G6PD deficient, 4 were HIV immunocompromised, and 29.7% were transfused. Among the degenerative complications, 2.4% had retinopathy, 1.9% osteonecrosis of the femoral head, 1.4% leg ulcers, and 0.8% cardiomyopathy. Salmonella typhi was the main cause of infection, 51.4% of the cases. The mean baseline hemoglobin level (n = 27) was 7.67 ± 1.64 g/dl. Four (0.4%) patients had a splenectomy. The mortality rate was 2.4%. The primary cause of death was anemia (28%), followed by sepsis in 20% of the cases. One case of suicide was documented as the cause of death. Conclusion: Outpatient medical follow-up of sickle cell patients is essential in sub-Saharan African countries where neonatal screening does not exist, and diagnosis is often late. The improvement in quality of life observed should be studied.

关键词： Sickle Cell Disease Outpatient Follow-Up Lomé

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A Novel γ-Alumina Supported Fe-Mo Bimetallic Catalyst for Reverse Water Gas Shift Reaction

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Chinese Journal of Chemical Engineering 2013年第9期21卷 1007-1014页

作者： Abolfazl Gharibi Kharaji Ahmad Shariati Mohammad Ali takassi Petroleum University of Technology Ahwaz Faculty of Petroleum Engineering Chemical Engineering DepartmentAhwaz Iran Petroleum University of Technology Ahwaz Faculty of Petroleum Engineering Science Department Ahwaz Iran

在反向的水气体，移动(RWGS ) 反应 CO2 被变换成能接着被用来生产象甲醇那样的有益的化学药品的公司。在现在的学习， Mo/Al2O3， Fe/Al2O3 和 Fe-Mo/Al2O3，催化剂是用受精方法的 synthesised。催化剂的结构用 X 光检查衍射(XRD ) 被... 详细信息

在反向的水气体，移动(RWGS ) 反应 CO2 被变换成能接着被用来生产象甲醇那样的有益的化学药品的公司。在现在的学习， Mo/Al2O3， Fe/Al2O3 和 Fe-Mo/Al2O3，催化剂是用受精方法的 synthesised。催化剂的结构用 X 光检查衍射(XRD ) 被学习， Brunauer-Emmett-Teller (赌注) 方法，诱导地联合的血浆原子排放分光计(ICP-AES ) ，温度规划了减小(H2-TPR ) ，公司化学吸着，精力散 X 光检查(EDX ) 和扫描电子显微镜学(SEM ) 技术。所有催化剂的运动性质为 RWGS 反应在一个批反应堆被调查。结果显示在 Fe-Mo/Al2O3 催化剂的结构的那瞬间存在作为与 Fe/Al2O3 相比提高它的活动。这改进可能由于更好的 Fe 分散和 Fe 种类的更小的粒子尺寸。Fe-Mo/Al2O3 催化剂的稳定性测试在一个固定的床反应堆和高公司收益被执行因为溪流上的时间的 60 h 被表明。3 阶段在新鲜、使用的催化剂的结构被发现的 Fe2 (MoO4 ) 。TPR 结果也显示 3 分阶段执行的 Fe2 (MoO4 ) 有低 reducibility，因此， 3 显著地分阶段执行的 Fe2 (MoO4 ) 在催化剂禁止留下的 Fe 氧化物的减小，导致了 Fe-Mo/Al2O3 的高稳定性催化剂。总的来说，这研究与高公司产量作为新奇催化剂介绍 Fe-Mo/Al2O3，几乎没有副产品并且为 RWGS 反应相当稳定。

关键词：水煤气变换反应双金属催化剂铁氧化物钼酸钆氧化铝负载电感耦合等离子体原子发射光谱仪 ICP-AES 扫描电子显微镜

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Fuzzy model prediction of Co(Ⅲ)/Al_2O_3 catalytic behavior in Fischer-Tropsch synthesis

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Journal of Natural Gas Chemistry 2011年第6期20卷 603-610页

作者： Mohammad Ali takassi Mahdi Koolivand Salooki Morteza Esfandyari Department of Science Petroleum CollegePetroleum University of Technology Oil&Gas Processing Center of Excellence Chemical Engineering DepartmentUniversity of Tehran Department of Chemical Engineering Faculty of EngineeringFerdowsi University of Mashad

The application of Co（Ⅲ）/Al2O3 catalyst in Fischer-Tropsch synthesis（FTS）was studied in a wide range of synthesis gas conversions and compared with Fuzzy Simulation *** study applies fuzzy model to predicting the product composition of CH4,CO2 and CO in Fischer-Tropsch process for natural gas synthesis,in which the input vector was 4-dimension including four variables（operating pressure, operating temperature,time and CO/H2 ratio）of 70 different experiments and the output product is a composition of CO2,CO and CH4. The Mamdani algorithm has been applied to the training of the fuzzy system and the test set was used to evaluate the performance of the system including R2,ARE,AARE and *** results demonstrated that the predicted values from the model were in good consistency with the experimental *** work indicates how fuzzy inference system（FIS）,as a promising predicting technique,would be effectively used in FTS.

关键词： fuzzy inference system Fischer-Tropsch natural gas catalyst Co (III) Al2O3

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Applying density functional theory on tautomerism in 3,4- dihydropyrimidin-2(1H)-ones

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中国化学前沿:英文版 2011年第2期6卷 142-146页

作者： Asadollah FARHADI Mohammad Ali takassi Faculty of Science University of Petroleum Technology AhwazAhwaz 61981-44471Iran

In the present study,the density functional theory(DFT)and Gibbs free energy calculations were performed to investigate the stability and tautomerism of C4-substituted-3,4-dihydropyrimidin-2(1H)-*** different forms are possible for the ethyl 3,4-dihydropyrimidinones(ethyl 4-aryl-6-methyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylates,ethyl 4-aryl-2-hydroxy-6-methyl-1,4-dihydropyrimidine-5-carboxylates and ethyl 4-aryl-2-hydroxy-6-methyl-3,4-dihydropyrimidine-5-carboxylates)forms that the most stable form is ethyl 4-aryl-6-methyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylates(keto-form).The obtained data showed that the substitution on the C4-substitut position can be effective on the equilibrium constant(K_(eq)).

关键词： Gibbs free energy density functional theory(DFT) tautomerism dihydropyrimidin-2(1H)-ones Keto-Form

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Investigation of the interaction of ethyl acetoacetate with nano alumina particle as Lewis acid in acetonitrile solvent

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中国化学前沿:英文版 2011年第3期6卷 248-252页

作者： Asadollah FARHADI Mohammad Ali takassi Mandana DAYER Faculty of Science Petroleum University of TechnologyAhwaz 61981-44471Iran Department of Chemistry Science and Research BranchIslamic Azad UniversityKhouzestanIran

The enol form of ethyl acetoacetate(EAA)displays interesting spectroscopic characteristics;this form of ethyl acetylacetate is very important in condensation *** this investigation,we have studied the interactions and the complex formation constants(K_(f))with nano alumina(10–20 nm)particle and alumina(mesh 135)compounds as Lewis acids in the acetonitrile solvent using absorption spectroscopy and related ***,in this study we calculated the thermodynamic parameters of this *** trend of reactivity of the ethyl acetoacetate(EAA)complexes toward the above Lewis acids,based on the solvent as follows:nano alumina compound>alumina compound.

关键词： complex formation constant ethyl acetoacetate nano alumina alumina thermodynamic

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Experimental investigation into L-Arg and L-Cys eco-friendly surfactants in enhanced oil recovery by considering IFT reduction and wettability alteration

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Petroleum Science 2020年第1期17卷 105-117页

作者： Hamed Foroughi Asl Ghasem Zargar Abbas Khaksar Manshad Mohammad Ali takassi Jagar A.Ali Alireza Keshavarz Department of Petroleum Engineering Abadan Faculty of Petroleum EngineeringPetroleum University of Technology(PUT)AbadanIran Department of Petroleum Engineering Ahwaz Faculty of Petroleum EngineeringPetroleum University of Technology(PUT)AhwazIran Department of Petroleum Engineering Faculty of EngineeringSoran UniversitySoranKurdistan RegionIraq Department of Petroleum Engineering College of EngineeringKnowledge UniversityErbilKurdistan RegionIraq School of Engineering Edith Cowan UniversityJoondalupWA 6027Australia

Surfactant flooding is an important technique used to improve oil recovery from mature oil reservoirs due to minimizing the interfacial tension(IFT)between oil and water and/or altering the rock wettability toward water-wet using various surfactant agents including cationic,anionic,non-ionic,and amphoteric *** this study,two amino-acid based surfactants,named lauroyl arginine(L-Arg)and lauroyl cysteine(L-Cys),were synthesized and used to reduce the IFT of oil–water systems and alter the wettability of carbonate rocks,thus improving oil recovery from oil-wet carbonate *** synthesized surfactants were characterized using Fourier transform infrared spectroscopy and nuclear magnetic resonance analyses,and the critical micelle concentration(CMC)of surfactant solutions was determined using conductivity,pH,and turbidity *** results showed that the CMCs of L-Arg and L-Cys solutions were 2000 and 4500 ppm,*** was found that using L-Arg and L-Cys solutions at their CMCs,the IFT and contact angle were reduced from 34.5 to 18.0 and15.4 mN/m,and from 144°to 78°and 75°,***,the L-Arg and L-Cys solutions enabled approximately 11.9%and 8.9%additional recovery of OOIP(original oil in place).It was identified that both amino-acid surfactants can be used to improve oil recovery due to their desirable effects on the EOR mechanisms at their CMC ranges.

关键词： Chemical EOR Amino-acid surfactant IFT Wettability Coreflooding

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Computational evaluation concerning the deviation of the atoms in 1-and 4-postions on the six-member ring and the effects on ^(1)HNMR chemical shift

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中国化学前沿:英文版 2011年第2期6卷 91-97页

作者： Asadollah FARHADI Mohammad Ali takassi Hamid Reza MEMARIAN Mousa SOLEYMANI Faculty of Science University of Petroleum TechnologyAhwaz 61981-44471Iran Department of Chemistry Faculty of ScienceUniversity of IsfahanIsfahan 81746-73441Iran

Density functional theory(DFT)calculations were carried out on some cyclohexane derivatives to investigate the deviation atoms on the 1-and 4-positions of chair *** deviations of chair plane of two position in the cyclohexane derivatives were calculated at the B3LYP/6–31++G(d,p)***,we investigated the correlation between deviations of two positions from chair plane on the chemical shift hydrogen atoms on the 4-position.

关键词： cyclohexane heterocyclohexane deviation B3LYP/6-31++G(d p) chemical shift

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Risk Factors for Birth Asphyxia in Togo: A Case-Control Study

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Open Journal of Pediatrics 2021年第4期11卷 816-831页

作者： Foli Agbeko Ayoko Améyo Kétévi Mawouto Fiawoo Bouwereou Bi-Labna Tata Kokouvi Evenyo Abalo elom ounoo takassi Baguilane Douaguibe Djatougbé Ayaovi Elie Akolly Homba Daké Batalia Rollin Arnaud Djomaleu Rachel Bayahou Kérékou Manani Hemou Mazama Pakoudjare Magnoulelen Nzonou Essèboè Koffitsè Sewu Sollim Talboussouma Bayaki Saka Deladem Komi Azoumah Edem Koffi Djadou Kokou Nadiedjoa Douti Adama Dodji Gbadoe Yawo Dzayissé Atakouma Paediatric Department University of Lomé Lomé Togo Paediatric Ward CHU Campus Lomé Togo Gynécology-Obstétric Ward CHU Sylvanus Olympio Gynecology-Obstetric Department University of Lomé Lomé Togo Paediatric Ward CHU Sylvanus Olympio Lomé Togo Paediatric Ward Bè Hospital Lomé Togo African Center of Research in Epidemiology and in Public Health Lomé Togo Paediatric Ward CHU Kara Kara Togo Dermatology Ward CHU Sylvanus Olympio Université of Lomé Lomé Togo Paediatric Department University of Kara Kara Togo

Background: Birth Asphyxia (BA) is one of the leading causes of neonatal death in developing countries. In Togo, 30.55% of neonatal deaths were related to BA and caused by several risk factors. The purpose of this piece of work is to analyse the antepartum, intrapartum, and foetal risk factors of BA. Methods: This is a case control study, conducted from 1st December 2019 to 28th February 2020 in obstetrics wards and at neonatal intensive care of paediatric ward at the Sylvanus Olympio university teaching hospital (CHU-SO) in Lomé, Togo. Neonates diagnosed with BA (Apgar score th minute) were considered as “cases” (N = 200) while neonates born either with normal vaginal delivery or by cesarean section having no abnormality were considered as “control” (N = 200). Results: The prevalence rate of BA was 9.13%. Age (p = 0.0391), gravidity (p = 0.0040), type of facility for prenatal follow-up (p 0.0001), use of Long-lasting impregnated mosquito nets (LLIN) (p 0.0001), notion of maternal fever (p 0.0001) and chronic pathology (p 0.0001) were related to occurrence of BA. Significant antepartum risk factors observed were age <

关键词： Birth Asphyxia Neonate Risk Factor Togo

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Pediatric HIV Infection in Togo: Situation of Child Care in the Central Region from 2008 to 2015

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World Journal of AIDS 2017年第4期7卷 260-268页

作者： F. Agbeko T. Guedehoussou K. D. Azoumah O. E. takassi M. Fiawoo K. A. R. Segbedji O. B. Tchagbele M. Kpegouni K. Tongon K. E. Djadou D. Y. Atakouma A. D. Agbere Service de Pédiatrie CHR-Lomé Commune Lomé Togo Service de Pédiatrie CHU Kara Kara Togo Service de Pediatrie CHU-Sylvanus Olympio Lomé Togo Service de Pédiatrie Centre Des Armées Lomé Togo

This piece of work covers thirteen (13) AIDS assistance programs sites over the period 1st January 2008 to 31st December 2015. The study is retrospective, descriptive, and cross-sectional based on 292 clinical cases of HIV infected children aged between 0 and 14 years old. A regional committee was charged to validate antiretroviral treatment (ART) prescriptions on a weekly basis. We have also used data from the regional committee register. HIV infected children represent 5.1% of casework on ART. The average starting age for ART was 4.5 years (1 - 180 months) with a sex ratio (Male/Female) of 0.9. The clinical classifications according to WHO guidelines were: Stage III (52.3%) and Stage IV (20.3%). The most frequent opportunistic infections were: wasting (40.12%), digestive candida infection (29.0%), acute respiratory infections (22.8%) and skin diseases (17.9%). The HIV type 1 was detected on all of the children (100%). The average rate of CD4 at the beginning of the ART was 552.98 cells/mm3, leading to a severe immuno-suppression in many cases (44.8%). The initial ART was essentially NEVIRAPINE + LAMIVUDINE + STAVUDINE. HIV infections diagnosis are usually late in the Central Region of Togo and will therefore be improved by the UNAIDS 90-90-90 strategic plan by 2020, through various initiatives. These are: the Prevention of Mother to Child HIV Transmission (PMTCT), the Early Infection Diagnosis (EID) based on Polymerase Chain Reaction (PCR) and the Provider Initiated Testing and Counseling (PITC).

关键词： HIV AIDS ART Children Togo

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