检索结果-南通市图书馆

Identification of four caspase genes from Spodoptera exigua (Lepidoptera: Noctuidae) and their regulations toward different apoptotic stimulations

引用

Insect Science 2020年第6期27卷 1158-1172页

作者： Huan Yu Zi-Qi Li Yi-Yi ou-yang Guo-Hua Huang Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests Hunan Agricultural UniversityChangshaChina College of Plant Protection Hunan Agricultural UniversityChangshaChina

Apoptosis plays critical roles in multiple biological processes in multicellular *** are known as important participators and regulators of ***,four novel caspase genes of Spodoptera exigua were cloned and characterized which were designated as SeCasp-1,SeCasp-6,ScCasp-7 and *** of the putative encoded protein sequences of these SeCasps indicated that SeCasp-1 and ScCasp-7 were possible homologs of executor caspases;SeCasp-8 was a possible homolog of initiator caspases;and SeCasp-6 was a unique caspase of *** that shares low similarity with all the identified insect *** on baculovirus expression system analyses,SeCasp-1 exhibited similar caspase activity to human caspase-1,-3,-4,-6,-8 and-9;SeCasp-6 presented similar caspase activity to human caspase-2,-3,-4,-6,-8 and-9;SeCasp-7 exhibited similar caspase activity to human caspase-2,-3 and-6;and SeCasp-8 presented similar caspase activity only to human *** with diiTcrent chemicals revealed that SeCasp-1 showed extreme upregulation after 24 h in the treated fat body cell line(IOZCAS-Spex-II)of *** expression analysis revealed that SeCasp-1 was highly transcribed in the larval stages,while SeCasp-6,SeCasp-7,SeCasp-H were *** in vivo detection of the relative expression levels of SeCasps in *** larvae inoculated with different pathogens suggested that SeCasp-J was sensitive to Bacillus thuringiensis infection and that SeCasp-6 was sensitive to baculovirus ***-7 and SeCasp-H showed slight changes under either in vitro chemical apoptosis induction or in vivo pathogen infection.

关键词： apoptosis apoptotic inducing insect caspase SeCasp Spodoptera exigua

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

血清淀粉样蛋白A与老年COPD患者肺弥散功能及运动受限的关联性分析

引用

中国临床新医学 2024年第1期17卷 79-86页

作者：欧阳钟粲野张树堂王卫重庆大学附属涪陵医院老年医学科重庆408000

目的分析血清淀粉样蛋白A(SAA)与老年慢性阻塞性肺疾病(COPD)患者肺弥散功能及运动受限的相关性。方法招募2020年1月至2021年7月重庆大学附属涪陵医院收治的188例老年稳定期COPD患者,均接受肺功能测试(PFT)和心肺运动试验(CPET)评估。... 详细信息

目的分析血清淀粉样蛋白A(SAA)与老年慢性阻塞性肺疾病(COPD)患者肺弥散功能及运动受限的相关性。方法招募2020年1月至2021年7月重庆大学附属涪陵医院收治的188例老年稳定期COPD患者,均接受肺功能测试(PFT)和心肺运动试验(CPET)评估。将肺一氧化碳弥散因子(T_(L)CO)<肺正常下限(LLN)的患者纳入弥散功能异常组(102例),T_(L)CO≥LLN的患者纳入弥散功能正常组(86例)。采用酶联免疫吸附试验(ELISA)测定患者SAA水平。采用Pearson相关分析探讨SAA水平与峰值摄氧量(VO_(2peak))的相关性。采用多因素logistic回归分析老年COPD患者肺弥散功能的影响因素。采用多元线性回归模型分析老年COPD患者的SAA水平与第1秒用力呼气容量的Z评分(FEV_(1Z-score))、FEV_(1)与预测值的百分比(ppFEV_(1))的关联性。采用受试者工作特征(ROC)曲线分析SAA水平对老年COPD患者肺弥散功能异常的预测效能。结果多因素logistic回归分析结果显示,较低的ppFEV_(1)、用力肺活量的Z评分(FVC_(Z-score))、(FEV_(1)/FVC)_(Z-score)是促进老年COPD患者肺弥散功能异常的独立危险因素(P<0.05),较高的ppFVC、FEV_(1)/FVC、肺泡通气量的Z评分(VA_(Z-score))是抑制老年COPD患者肺弥散功能异常的独立保护因素(P<0.05)。弥散功能异常组SAA水平显著高于弥散功能正常组[(135.09±58.05)ng/mL vs(78.10±32.81)ng/mL,t=8.079,P<0.001]。ROC曲线分析结果显示,SAA水平具有预测老年COPD患者肺弥散功能异常的应用价值[AUC(95%CI)=0.797(0.735~0.860),P<0.001],最佳截断值为85.07 ng/mL,其对应的灵敏度和特异度分别为77.50%和69.80%。多元线性回归分析结果显示,FEV_(1Z-score)与ppFEV_(1)每降低一个单位,弥散功能异常组患者的SAA水平分别升高0.009(95%CI:-0.013~-0.005)ng/mL、0.149(95%CI:-0.210~-0.088)ng/mL。Pearson相关分析结果显示,老年COPD患者的SAA水平与VO_(2peak)呈负相关(r=-0.512,P<0.001)。结论在老年COPD患者中,SAA水平与FEV_(1Z-score)有关,检测SAA水平有助于鉴别老年COPD肺弥散功能异常患者。此外,SAA水平与VO_(2peak)呈负相关,说明导致FEV_(1)降低的机制可能有助于解释老年COPD肺弥散功能异常患者运动受限的原因。

关键词：血清淀粉样蛋白A 慢性阻塞性肺疾病肺气肿表型运动耐力

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Interfacial engineering regulated by CeOx to boost efficiently alkaline overall water splitting and acidic hydrogen evolution reaction

引用

Journal of Materials Science & Technology 2022年第25期120卷 129-138页

作者： Jian Chen Zhen Hu yang ou Qinghua Zhang Xiaopeng Qi Lin Gu Tongxiang Liang College of Rare Earth Jiangxi University of Science and TechnologyGanzhou 341000China Faculty of Materials Metallurgy and Chemistry Jiangxi University of Science and TechnologyGanzhou 341000China Institute of Physics Chinese Academy of ScienceBeijing 100190China

Development of a low-cost and durable bifunctional electrocatalyst with high catalytic activity by hybridizing rare earth metal and non-noble metal is of utmost ***,a bifunctional electrocatalyst consisting of MoO_(2)and CeO_(x)heterostructure is synthesized via interfacial ***,due to its unique hetero-interface with abundant oxygen vacancies,the MoO_(2)-CeO_(x)_(x)/NF is able to exhibit outstanding hydrogen evolution reaction(HER) performance with an overpotential of 26 mV at 10 mA cm^(-2),and a preferable oxygen evolution reaction(OER) overpotential of 272 mV at 100 mA cmin 1 M *** recorded HER and OER overpotentials of MoO_(2)-CeO_(x)/NF are clearly smaller than those of Pt/C(HER overpotential of 27 mV) and RuO(OER overpotential of 393 mV) at the same current *** importantly,MoO_(2)-CeO_(x)/NF can also exhibit good HER activity with an overpotential of 50 mV at 10 mA cmin acidic ***,it is expected that this work can offer a new approach in the realization of high-catalytic alkaline overall water splitting and acidic HER performance through the rational design of rare-earth metal and non-noble metal heterostructure.

关键词： Heterostructure Oxygen vacancies Cerium oxide Overall water splitting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于区块链技术的工业产品信息追溯方法仿真

引用

计算机仿真 2024年第3期41卷 232-236页

作者：戴欧阳尤通胡洪林桂林信息科技学院广西桂林541004 太原科技大学山西太原030024

为了有效解决工业产品信息追溯困难以及耗时比较长等问题,提出一种区块链技术下工业产品信息追溯方法。分析区块链技术的组成架构,改进区块链中的共识算法,通过改进共识算法降低区块链系统对节点容纳数量的限制,提升系统数据吞吐能力。... 详细信息

为了有效解决工业产品信息追溯困难以及耗时比较长等问题,提出一种区块链技术下工业产品信息追溯方法。分析区块链技术的组成架构,改进区块链中的共识算法,通过改进共识算法降低区块链系统对节点容纳数量的限制,提升系统数据吞吐能力。通过优化处理后的区块链技术,设计基于区块链技术下的工业产品信息追溯方案,并给出详细了的工业产品信息追溯流程。通过仿真分析可知,采用所提方法能够获取更加准确的工业产品信息追溯结果,且耗时较短,可以有效保证产业信息的安全性,适用于工业产品信息追溯研究。

关键词：区块链技术工业产品信息追溯共识算法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

3H-31, A Non-structural Protein of Heliothis virescens ascovirus 3h,Inhibits the Host Larval Cathepsin and Chitinase Activities

引用

Virologica Sinica 2021年第5期36卷 1036-1051页

作者： Huan Yu Yi-Yi ou-yang Chang-Jin yang Ni Li Madoka Nakai Guo-Hua Huang Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests Hunan Agricultural UniversityChangsha 410128China College of Plant Protection Hunan Agricultural UniversityChangsha 410128China Tokyo University of Agriculture and Technology SaiwaiFuchuTokyo 183-8509Japan

3h-31 of Heliothis virescens ascovirus 3h(Hv AV-3h)is a highly conserved gene of *** an early gene of Hv AV-3h,3h-31 codes for a non-structural protein(3H-31)of Hv *** the study,3h-31 was initially transcribed and expressed at 3 h post-infection(hpi)in the infected Spodoptera exigua fat body cells(Se FB).3h-31 was further inserted into the bacmid of Autographa californica nucleopolyhedrovirus(Ac MNPV)to generate an infectious baculovirus(Ac MNPV-31).In vivo experiments showed that budded virus production and viral DNA replication decreased with the expression of 3H-31,and lucent tubular structures were found around the virogenic stroma in the Ac MNPV-31-infected Se FB *** vivo,both LD50and LD90values of Ac MNPV-31 were significantly higher than those of the wild-type Ac MNPV(Ac MNPV-wt)in third instar *** *** interesting finding was that the liquefaction of the larvae killed by the infection of Ac MNPV-31 was *** and cathepsin activities of Ac MNPV-31-infected larvae were significantly lower than those of Ac MNPV-wt-infected *** possible regulatory function of the chitinase and cathepsin for 3H-31 was further confirmed by RNAi,which showed that larval cathepsin activity was significantly upregulated,but chitinase activity was not significantly changed due to the RNAi of *** on the obtained results,we assumed that the function of 3H-31 was associated with the inhibition of host larval chitinase and cathepsin activities,so as to restrain the hosts in their larval stages.

关键词： Cathepsin Chitinase Heliothis virescens ascovirus 3h(HvAV-3h) Recombinant virus 3h-31

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characteristics of plasma in a novel laser-assisted pulsed plasma thruster

引用

Plasma Science and Technology 2022年第7期24卷 3-14页

作者： Yuanzheng ZHAO Yu ZHANG Jianjun WU yang ou Peng ZHENG College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073People's Republic of China

A novel laser-assisted pulsed plasma thruster(LA-PPT)is proposed as an electric propulsion thruster,which separates laser ablation and electromagnetic *** aims for a higher specific impulse than that achieved with conventional *** to the short-time discharge and the novel configuration,the physical mechanism of the discharge is *** and spatial-resolved optical emission spectroscopy was applied to investigate the variation in the plasma properties in the thruster discharge *** plasma species,electron temperature,and electron density were obtained and *** investigation revealed that there were H_(α),H_(β),H_(γ),H_(ε) atoms,CⅠ,CⅡ,CⅢ,CⅣ,ClⅠ,ClⅡparticles,and a small amount of CH,C_(3),C_(2),H_(2) neutral molecular groups in the *** electron temperature of the discharge channel of the thruster was within 0.6–4.9 e V,and the electron density was within(1.1–3.0)×10^(18)cm^(-3),which shows that the optical emission spectroscopy method is to measure the electron excitation temperature and electron density in heavy *** the Langmuir probe method is to measure the temperature and density of free *** use of laser instead of spark plug as the ignition mode significantly changed the plasma distribution in the discharge *** the conventional PPT,which has high electron density near the thruster surface,LAPPT showed relatively large electron density at the thruster outlet,which increased the thruster specific *** addition,the change in the ignition mode enabled the electron density in the LA-PPT discharge channel to be higher than that in the conventional *** proves that the ignition mode with laser replacing the spark plug effectively optimised the PPT performance.

关键词： laser-assisted pulsed plasma thruster plasma properties time and spatial-resolved optical emission spectroscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigation on plasma characteristics in a laser ablation pulsed plasma thruster by optical emission spectroscopy

引用

Plasma Science and Technology 2020年第4期22卷 83-89页

作者： Yu ZHANG Jianjun WU yang ou Daixian ZHANG Jian LI College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073People’s Republic of China China Aerodynamics Research and Development Center Mianyang 621000People's Republic of China

In order to further improve the propulsion performance of pulsed plasma thrusters for space micro propulsion,a novel laser ablation pulsed plasma thruster is proposed,which separated the laser ablation and electromagnetic *** emission spectroscopy is utilized to investigate the plasma characteristics in the *** spectral lines at different times,positions and discharge intensities are experimentally recorded,and the plasma characteristics in the discharge channel are concluded through analyzing the variation of spectral *** the discharge energy of 24 J,laser energy of 0.6 J and the use of aluminum propellant,the specific impulse and thrust efficiency reach 6808 s and 70.6%,respectively.

关键词： laser ablation pulsed plasma thruster optical emission spectroscopy plasma propulsion performance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microstructure evolution and liquid phase separation in Ta-O hypermonotectic melts during laser-cladding

引用

China Foundry 2018年第3期15卷 222-227页

作者： Hai-ou yang Meng Wang Xin Lin Wei-dong Huang State Key Laboratory of Solidification Processing Northwestern Polvtechnical University Xi'an Shaanxi 710072 PR China MHT Key Laboratory of Metal High Performance Additive Manufacturing and Innovative Design Northwestern Polytechnical University Xi'an Shaanxi 710072 PR China

A three-layer Ta_2O_5-containing coating was successfully fabricated by laser cladding on a pure Ta substrate. The maximum thickness of such a coating is about 1.6 mm. The microstructure, phase constitution and elemental distribution in the coating were investigated. Results show that the coating has been metallurgically bonded to the Ta substrate and the microstructure exhibits a graded change along the deposition direction from Ta substrate to the top of coating. In the layers I and II of the graded coating, the microstructure evolution can be confi rmed as a result of hypomonotectic reaction, but in the layer Ⅲ it was formed by hypermonotectic reaction. At the top of coating, the microstructure was still homogeneous although liquid phase separation had occurred, which can be attributed to the fact that the O-rich droplets do not have enough time to fl oat at high cooling rate. The theoretical calculation results show that during laser cladding, the solidifi cation time of the melt pool was less than 0.1 s, which fi ts well with the results from the experiment.

关键词： Laser cladding liquid phase separation microstructure evolution homogeneous structure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Quantum Chemistry Study of Inhibition Properties of Imidazole and Its Derivatives on Iron Surface Corrosion

引用

Chemical Research in Chinese Universities 2001年第3期17卷 305-310页

作者： YAN Xiao-ci XIA Wen-bing LIU Jie ou yang-li LUO Ming-dao yang Feng MIN Xin-min Department of Chemistry Wuhan UniversityWuhan 430072P.R.China National Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070P.R.China

The geometries of imidazole and its derivatives were respectively optimized by using ab initio method, and the molecular orbital energy levels and the charge densities were obtained for their optimum geometries. The frontier orbital energy levels, and the net charges of N (1) atom and the imidazole ring of those molecules were obtained with ab initio and SCC-DV-Xα methods. It was found that the inhibition properties of those compounds change with the highest occupied molecular orbital energy levels, and the net charges of N (1) atom. We took four iron atoms on the crystal plane (100) of α-iron as the surface which was used to study the adsorption towards the inhibitors. The adsorption models of the inhibitor to be adsorbed on the Fe-cluster surface were optimized with SCC-DV-Xα method. It turns out that the most favorable model is that the inhibitor molecule is adsorbed on the Fe-cluster surface in an inclined state. The calculation shows that the stabilization energies of the systems are well correlated with the inhibition efficiencies.

关键词： Imidazole ab initio SCC-DV-Xα algorithm Fe-cluster surface Inhibition efficiency

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A new family of supramolecular multiferrocenyl rhomboids:Synthesis,characterization,and their electrochemical behavior

引用

Chinese Chemical Letters 2013年第6期24卷 471-474页

作者： Jiang-Kun ou-yang Li-Jun Chen Lin Xu Cui-Hong Wang Hai-Bo yang Shanghai Key Laboratory of Green Chemistry and Chemical Processes Department of ChemistryEast China Normal University

Two novel,supramolecular,multiferrocenyl rhomboids 5 and 6 have been successfully constructed from newly designed 60 ferrocenyl donor precursor 1 via coordination-driven *** structures of all multiferrocenyl rhomboids were characterized by multinuclear NMR（~1H and ^（31）P）,CSI-TOF-MS, and PM6 semi-empirical molecular simulation,and their electrochemical behaviors have been investigated.

关键词： Supromolecular metallacycle Coordination-driven self-assembly Multiferrocenyl rhomboid Electrochemical behavior

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：