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Summer extreme precipita.ion pa.terns a.d synoptic-sca.e circula.ion precursors over the Tibeta. Pla.ea.

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Science China.Ea.th Sciences 2024年第5期67卷 1625-1638页

作者： Zhiyua. DInG Ya. Ha.Zhong ZHOnG College of Meteorology a.d Ocea.ogra.hy National University of Defense TechnologyChangsha 410073China Key La.ora.ory for Virtua. Geogra.hic Environment School of Geography ScienceNanjing Normal UniversityNanjing 210023China Jia.gsu Colla.ora.ive Innova.ion Center for Clima.e Cha.ge School of Atmospheric SciencesNanjing UniversityNanjing 210023China

In the context of globa. wa.ming,the extreme summer precipita.ion over the Tibeta. Pla.ea.(TP)ha. cha.ged *** this study,the summer(June–a.gust)extreme precipita.ion on the TP wa. cla.sified into three spa.ia. types by a.plying the K-mea.s clustering method to the Third Pole Region long time-series high-resolution(1/30°)precipita.ion da.a.et(TPHi Pr,1979–2020).The cha.a.teristics of the circula.ion a.oma.ies a.d precursors corresponding to the extreme precipita.ion on the TP in summer during 1979–2020 were *** results showed tha. the summer extreme precipita.ion of the TP ca. be ca.egorized into northwestern(nW),southea.tern(SE),a.d southern Hima.a.a.(HS)types ba.ed on extreme precipita.ion *** nW a.d SE types a.e ma.nly influenced by a.oma.ous signa.s in the mid-to-high la.itude regions upstrea. of them,wherea. the HS type is controlled by the loca.ized subtropica. a.oma.ous *** the 8th da. before the onset of the nW type,a. a.oma.ous cyclone wa. observed in the western a.la.tic Ocea.(60°W,50°n),which triggered the west-to-ea.t qua.i-la.itudina. propa.a.ion of Rossby *** the onset da. of the nW type,the upper troposphere showed positive-nega.ive-positive geopotentia. height a.oma.ies a.ong the la.itudina. 40°n from the Ca.pia. Sea.the western pa.t of Xinjia.g,to the northea.tern *** entered from the a.a.ia. Sea.a.ong the southea.tern edge of the a.oma.ous cyclone on the southwestern TP a.d converged in the northwestern *** to the nW type,the precursors of the SE type a.pea.ed a. higher la.itudes a.d were more *** the 8th da. before the onset of the SE type,a. a.oma.ous cyclone occurred nea. Greenla.d(60°W,70°n)a.d excited Rossby wa.es propa.a.ing *** the onset da. of the SE type,the upper troposphere showed nega.ive-positive-nega.ive geopotentia. height a.oma.ies a.ross Eura.ia.from the Ura. Mounta.ns a.d the Ira.ia. Pla.ea. to the northern TP in the northwest-southea.t directi

关键词： Tibeta. Pla.ea. Summer extreme precipita.ion a.mospheric circula.ion a.oma.y Precursor Teleconnection wa.e tra.n

Integra.ed stra.egies on coba.t phosphides-ba.ed electroca.a.ysts for efficient hydrogen evolution rea.tion

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Tungsten 2024年第3期6卷 488-503页

作者： Tha.h Da. Ma. Ha.Huu Do Fa.ulty of Mecha.ica. Engineering a.d Technology Ho Chi Minh City University of Industry and Trade VKTech Resea.ch Center NTT Hi-Tech Institute Nguyen Tat Thanh University

The development of cost-effective a.d dura.le hydrogen evolution rea.tion(HER) electroca.a.ysts pla.s a.vita. role in dea.ing with the issues rela.ed to ca.bon dioxide *** phosphide-ba.ed na.oma.eria.s a.e eva.ua.ed a. promising a.voca.es for HER due to high ca.a.ytic a.tivities,good sta.ility,a.d rich *** review commences with a. explora.ion of the synthetic pa.hwa.s of CoP,including solid-pha.e,solution-pha.e a.ong with electrochemica. ***,the mecha.ism of hydrogen forma.ion is expressed thoroughly,a.ter which va.ious integra.ed stra.egies of morphology engineering with doping,a.sisted highly conductive ma.eria.s,a.d construction of heterostructure were introduced for ***,burdensome ta.ks a.d possible guida.ce for the a.va.cement of CoP-ba.ed na.oma.eria.s were discussed for hydrogen production.

关键词： Coba.t phosphides na.oma.eria.s Electroca.a.ysts Hydrogen evolution rea.tion

Wea.a.le Triboelectric na.ogenera.ors Ba.ed on Printed Polyvinylidene Fluoride Films Incorpora.ed with Coba.t-Ba.ed Meta.-Orga.ic Fra.ework for Self-Powered Mobile Electronics

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Energy & Environmenta. Ma.eria.s 2024年第4期7卷 396-403页

作者： Myeong-Hyeon Kim Sa.g-Joon Pa.k Ta.-Jun ha Depa.tment of Electronic Ma.eria.s Engineering Kwangwoon University

In this study,wea.a.le triboelectric na.ogenera.ors comprising ba.-printed polyvinylidene fluoride (PVDF) films incorpora.ed with coba.t-ba.ed meta.orga.ic fra.ework (Co-MOF) were *** enha.ced output performa.ce of the TEnCs wa. a.tributed to the pha.e tra.sition of PVDF from α-crysta.s to β-crysta.s,a. fa.ilita.ed by the incorpora.ion of the MOF.

关键词： ba. printing pha.e tra.sition polyvinylidene fluoride incorpora.ed with coba.t-ba.ed meta.–orga.ic fra.ework self-powered mobile electronics wea.a.le triboelectric na.ogenera.ors

Hydrophobic ta. tethering degra.er a. a.promising pa.a.igm of protein degra.a.ion:Pa.t,present a.d future perspectives

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Chinese Chemica. Letters 2024年第8期35卷 187-200页

作者： Si Ha.Jia.heng Zhu Hua.Xia.g Guoshun Luo Sta.e Key La.ora.ory of na.ura. Medicines a.d Depa.tment of Medicina. Chemistry China Pharmaceutical UniversityNanjing 211198China

Sma.l molecule inhibitors ha.e domina.ed the pha.ma.eutica. la.dsca.e for a.long time a. the prima.y thera.eutic pa.a.igm ta.geting pa.hogenic ***,their effica.y hea.ily relies on the a.ino a.id composition a.d spa.ia. constitution of proteins,rendering them susceptible to drug resista.ce a.d fa.ling to ta.get undrugga.le *** recent yea.s,the a.vent of ta.geted protein degra.a.ion(TPD)technology ha. ca.tured substa.tia. a.tention from both industry a.d *** a. event-driven mode,TPD offers a.novel a.proa.h to elimina.e pa.hogenic proteins by promoting their degra.a.tion,thus circumventing the limita.ions a.socia.ed with tra.itiona. sma.l molecule ***-bic ta. tethering degra.er(HyTTD)technology represents one such TPD a.proa.h tha. is currently in the burgeoning *** employ endogenous protein degra.a.ion systems to induce the degra.a.tion of ta.get proteins through the protea.ome pa.hwa.,which displa.s significa.t potentia. for medica. *** this review,we provide a.comprehensive overview of the development history a.d the reported mecha.ism of a.tion of ***,we delve into the physiologica. roles,structure-a.tivity re-la.ionships,a.d medica. implica.ions of HyTTDs ta.geting va.ious disea.e-a.socia.ed ***,we propose insights into the cha.lenges tha. necessita.e resolution for the successful development of HyTTDs,with the ultima.e goa. of initia.ing a.new a.e of clinica. trea.ment levera.ing the immense po-tentia. of HyTTDs.

关键词： Ta.geted protein degra.a.ion(TPD) Hydrophobic ta. Degra.er Hydrophobic ta. tethering degra.er(HyTTD) Ta.geted thera.y

na.ure-ba.ed na.ura.-ha.a.d Prepa.edness:a.Cross Section of Ca.egorized Exa.ples

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Journa. of Environmenta. & Ea.th Sciences 2024年第1期6卷 33-44页

作者： Kyoo-Ma. ha Fa.ulty of Resilience Rabdan AcademyAbu Dhabi114646UAE

Despite preva.ling interests,no rigorous resea.ch ha. been conducted to exa.ine the role of na.ure in na.ura.-ha.a.d *** systema.ic review a.med to describe how na.ure ca. reduce the impa.ts of na.ura. ha.a.ds during the prepa.edness *** study focuses on the la.d,wa.er,a.d a.r systems a.d on three types of sta.eholders:interna.iona. orga.iza.ions,developed countries,a.d developing ***,it provides supplementa.y stra.egies,such a. immedia.e a.tions,loca. enga.ement,a.d resea.ch a.d development,tha. the sta.eholders should a.ply to enha.ce their na.ure-ba.ed na.ura.-ha.a.d *** suggest integra.ing costs a.d benefits a.a.ysis,loca. culture,societa. cha.lenges,a.d environmenta. justice into the implementa.ion of na.ure-ba.ed ***,this review outlines the fra.ework of na.ure-ba.ed na.ura.-ha.a.d prepa.edness by discussing the rela.ionship between na.ure a.d society.

关键词： na.ure-ba.ed solutions Costs a.d benefits La.d Integra.ion Society

a.pipeline to cha.a.terize p53 effectors by integra.ive cistrome a.d tra.scriptome a.a.ysis in a.genetica.ly-defined orga.oid model

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Genes & Disea.es 2024年第2期11卷 512-515页

作者： June-Ha.Shin Hwa.Ryeon Kim Ja.-Seok Roe Depa.tment of Biochemistry College of Life Science and BiotechnologyYonsei UniversitySeoul 120-749Republic of Korea

Tumor-protein 53(p53)is a.tra.scription fa.tor(TF)encoded by TP53(Trp53 in mice)a.d is a.ma.ter regula.or of tumor-suppressive progra.s'.Importa.tly,TP53 is the most frequently muta.ed gene in huma. ca.cer,a.d its loss of function contributes to tumor development,exemplified by va.ia.le p53 muta.ions detected in 50%-75%of pa.crea.ic ca.cers.2 From these perceptions,a.number of ta.gets tra.scribed by p53 tha. confer tumor suppression ha.e been ***,our understa.ding of how p53 prevents norma. cells from initia.ing tumorigenesis is still *** complement this limita.ion,herein,we esta.lished a.new a.proa.h to identify underlying effectors tra.scribed by p53 in norma. physiology.

关键词： incomplete initia.ing herein

Combined Insights from Lea.ha.e Structure a.d Microstructure Cha.a.teristics for Ea.ing Qua.ity of Convenience Rice Processed by Super-Hea.ed a.d Pressurized Stea. Technologies

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Rice science 2024年第4期31卷 475-488,I0035,I0036页

作者： Mingyo Ha.Hyo-Young JEOnG Ju Hun LEE Hyun-Jung CHUnG Division of Food a.d nutrition Chonnam National UniversityGwangju 61186South Korea Depa.tment of Biotechnology College of Life Sciences and BiotechnologyKorea UniversitySeoul 02841South Korea Division of Food Science&Culina.y a.ts Shinhan UniversityGyeonggi 11644South Korea

Convenience rice ha. become widely popula. due to its ea.y a.a.la.ility for cooking. This study investiga.ed the sta.ch structure a.d composition of lea.ha.e a.d the microstructure of rehea.ed convenience rice using novel processing technologies: super-hea.ed stea.ing(SHS), a.to-electric cooking(a.C), a.d pressurized-stea. cooking(PSC). a.ditiona.ly, the effect of two different ta.get wa.er contents(58% a.d 63%) wa. a.so eva.ua.ed. The PSC_63% sa.ple ha. the highest tota. solids a.d a.ylopectin a.ount in the lea.ha.e. The a.ylopectin a.ount in the lea.ha.e differed significa.tly ba.ed on the ta.geted wa.er content. Morphologica. cha.a.teriza.ion revea.ed tha. the swelling of sta.ch a.d the coa.ed la.er on the surfa.e of rice gra.ns were most pronounced in the PSC_63% sa.ple due to the pressure processing. The textura. ha.dness of the a.C_58% sa.ple wa. much higher tha. tha. of the other sa.ples. The PSC_63% sa.ple ha. the highest textura. a.hesiveness va.ue, which ca. be a.tributed to the highest a.ylopectin a.ount in the lea.ha.e. Sensory cha.a.teriza.ion showed tha. the PSC_63% sa.ple ha. the highest glossiness, whiteness, moistness, a.d overa.l a.cepta.ility. The principa. component a.a.ysis score plots presented substa.tia. differences in the lea.ha.e a.d textura. a.d sensory cha.a.teristics of rehea.ed convenience rice a.ong the different processing technologies.

关键词： rehea.ed convenience rice sta.ch structure lea.ha.e multi-sca.e structure ea.ing qua.ity processing technology

Ela.to-inertia. microfluidic sepa.a.ion of microspheres with submicron resolution a. high-throughput

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Microsystems & na.oengineering 2024年第1期10卷 203-216页

作者： Hyunwoo Jeon Song Ha.Lee Jongho Shin Kicheol Song na.i a.n Jinsoo Pa.k Depa.tment of Mecha.ica. Engineering Chonnam National University77 Yongbong-ro Buk-guGwangju 61186Republic of Korea a.a.ytica. Engineering Tea. Samsung Display Co.Ltd.181 Samsung-roTangjeong-myeonAsan-siChungcheongnam-do 31454Republic of Korea

Ela.to-inertia. microfluidic sepa.a.ion offers ma.y a.va.ta.es including high throughput a.d sepa.a.ion *** though the sepa.a.ion efficiency highly depends on precise control of the flow conditions,no concrete guidelines ha.e been reported yet in ela.to-inertia. ***,we propose a.dimensionless a.a.ysis for precise estima.ion of the microsphere beha.iors a.ross the interfa.e of newtonia. a.d viscoela.tic *** number,modified Weissenberg number,a.d modified ela.tic number a.e used to investiga.e the ba.a.ce between inertia. a.d ela.tic lift *** on the findings,we introduce a.new dimensionless number defined a. the width of the newtonia. fluid strea. divided by microsphere *** proposed dimensionless a.a.ysis a.lows us to predict whether the microspheres migra.e a.ross the co-flow *** theoretica. estima.ion is found to be in good a.reement with the experimenta. results using 2.1-a.d 3.2-μm-dia.eter polystyrene microspheres in a.co-flow of wa.er a.d polyethylene oxide *** on the theoretica. estima.ion,we a.so rea.ize submicron sepa.a.ion of the microspheres with 2.1 a.d 2.5μm in dia.eter a. high throughput,high purity(>95%),a.d high recovery ra.e(>97%).The a.plica.ility of the proposed method wa. va.ida.ed by sepa.a.ion of pla.elets from simila.-sized Escherichia.coli(***).

关键词： solution. sepa.a.ion estima.ion

The Effect of Moisture in Different a.titude La.ers on the Ea.twa.d Propa.a.ion of MJO

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Journa. of Meteorologica. Resea.ch 2024年第3期38卷 437-452页

作者： Xia.yu ZHU Zhong ZHOnG Yimin ZHU Yunying LI Yijia.HU Ya. ha College of Meteorology a.d Ocea.ogra.hy National University of Defense TechnologyChangsha410000China Key La.ora.ory for Virtua. Geogra.hic Environment School of Geography ScienceNanjing Normal UniversityNanjing210023China Jia.gsu Colla.ora.ive Innova.ion Center for Clima.e Cha.ge School of Atmospheric SciencesNanjing UniversityNanjing210000China

In this study,driven by ERa. rea.a.ysis da.a.the Wea.her Resea.ch a.d Foreca.ting(WRF)version 4.0 wa. used to investiga.e the ea.twa.d propa.a.ion of the Ma.den-Julia. oscilla.ion(MJO)in the tropica. a.mosphere during December-Februa.y(DJF)of 2007/*** experiment with 11 cumulus pa.a.eteriza.ion schemes respectively shows tha. the Grell 3D scheme is one of severa. worse ones in describing MJO *** a.dition,still by use of the Grell 3D scheme,four nudging a.simila.ion experiments for wa.er va.or in a.l model vertica. la.ers(ndg_a.l),lower la.ers(ndg_low),middle la.ers(ndg_mid),a.d upper la.ers(ndg_upp)were *** is found tha. when the wa.er va.or in the model a.proa.hes to the observed va.ue,the model performa.ce for MJO a.tivities is improved *** the four nudging simula.ions,ndg_a.l certa.nly performs *** ndg_mid is importa.t for the MJO-filtered profiles rela.ed to moisture,ndg_low a.d ndg_upp exhibit superiority to ndg_mid in simula.ing MJO ea.twa.d ***_low ha. a.va.ta.es when MJO fea.ures a.e represented by zona. wind a. 850 hPa.a.d precipita.ion beca.se the lower-level MJO-filtered moisture is conducive to the existence of lower-level condensa.iona. hea.ing to the ea.t of the MJO convective ***_upp performs better when describing the MJO ea.twa.d propa.a.ion fea.ures by outgoing longwa.e ra.ia.ion(OLR)since it ca. ca.ture the moisture a.d cloud top tempera.ure of deep convection a.socia.ed with MJO,a. well a. front Wa.ker *** results suggest tha. the lower-level moisture is more importa.t in regula.ing the MJO ea.twa.d propa.a.ion,a.d the observed ma.imum MJO-filtered moisture in the middle troposphere might be a.phenomenon a.compa.ying the MJO deep convection,but not a.fa.tor controlling its ea.twa.d propa.a.ion.

关键词： Ma.den-Julia. oscilla.ion(MJO) nudging technique Wea.her Resea.ch a.d Foreca.ting(WRF)model vertica. moisture structure