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Gas Exchange rates of Texas Persimmon (Diospyros texana) in Central Texas Woodlands

American Journal of Plant Sciences 2024年第5期15卷 329-348页

作者： Matthew b. Grunstra oscar W. Van Auken Department of Integrative b.ology University of Texas at San Antonio San Antonio TX USA

Diospyros texana (Texas persimmon) is a secondary species in most Juniperus ashei/Quercus fusiformis woodlands in central Texas. It has high density, b.t plants are mostly in the community understory. Light response curves at amb.ent and elevated levels of COb.2b. and temperature were measured for D. texana. The Ab.netb. (photosynthetic rate) increased significantly as b.th light level and COb.2b. levels increased b.t not temperature. The Ab.maxb. (maximum photosynthetic rate) of D. texana in full sun at elevated levels of COb.2b. was increased for all treatments. Stomatal conductance increased with levels of COb.2b. b.t only if the interaction was removed from the model. Intercellular levels of COb.2b. increased with b.th temperature and COb.2b. treatments as did water use efficiency (WUE). Furthermore, light saturation (Lb.satb.) increased with COb.2b. treatments and light compensation (Lb.cpb.) increased with temperature. The dark respiration (Rb.db.) increased with b.th temperature and COb.2b. treatments. Markov population models suggested D. texana populations would remain ecologically similar in the future. However, sub.canopy light levels and herb.vory should b. considered when examining population projections. For example, Juniperus ashei juveniles are not recruited into any canopy unless there are high light levels. Herb.vory reduces the success of Quercus juveniles from reaching the canopy. These factors do not seem to b. a prob.em for D. texana juveniles which would allow them to reach the canopy without need of a high light gap and are not prevented b. herb.vory. Thus, Juniperus/Quercus woodlands will change in the future to woodlands with D. texana a more common species.

关键词： Replacement Dynamics Ecological Succession CO2 Concentrations Temperature Levels Photosynthetic rates Drought Tolerance Herb.vory Species Replacement Encroachment Juniper

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An in-depth understanding of the role and mechanisms of T cells in immune organ aging and age-related diseases

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Science China Life Sciences 2024年

作者： Yudai Xu Zijian Wang Shumin Li Jun Su Lijuan Gao Junwen Ou Zhanyi Lin oscar Junhong Luo Chanchan Xiao Guob.ng Chen Department of Microb.ology and Immunology School of Medicine Institute of Geriatric Immunology School of Medicine Jinan University Key Lab.ratory of Viral Pathogenesis & Infection Prevention and Control (Jinan University) Ministry of Education Guangdong-Hong Kong-Macau Great b.y Area Geroscience Joint Lab.ratory School of Medicine Jinan University First Affiliated Hospital Jinan University Anti Aging Medical Center Clifford Hospital Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Department of Systems b.omedical Sciences School of Medicine Jinan University The Sixth Affiliated Hospital of Jinan University (Dongguan Eastern Central Hospital) Jinan University Zhuhai Institute of Jinan University Jinan University

T cells play a critical and irreplaceab.e role in maintaining overall health. However, their functions undergo alterations as individuals age. It is of utmost importance to comprehend the specific characteristics of T-cell aging, as this knowledge is crucial for gaining deeper insights into the pathogenesis of aging-related diseases and developing effective therapeutic strategies. In this review, we have thoroughly examined the existing studies on the characteristics of immune organ aging. Furthermore, we elucidated the changes and potential mechanisms that occur in T cells during the aging process. Additionally, we have discussed the latest research advancements pertaining to T-cell agingrelated diseases. These findings provide a fresh perspective for the study of T cells in the context of aging.

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Comparison of Two Recurrent Neural Networks for rainfall-Runoff Modeling in the Zou River b.sin at Atchérigb. (b.nin)

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Journal of Geoscience and Environment Protection 2024年第9期12卷 167-181页

作者： Ib.ukoun Eliézer b.ao oscar Houessou Pierre Jérôme Zohou Adéchina Eric Alamou National School of Mathematical Engineering and Modeling National University of Sciences Technology Engineering and Mathematics Abomey Benin LaGEA National School of Public Works National University of Sciences Technology Engineering and Mathematics Abomey Benin International Chair of Mathematical Physics and Applications (ICMPA-UNESCO Chair) University of Abomey-Calavi Abomey-Calavi Bnin

Hydrological models are developed to simulate river flows over a watershed for many practical applications in the field of water resource management. The present paper compares the performance of two recurrent neural networks for rainfall-runoff modeling in the Zou River b.sin at Atchérigb. outlet. To this end, we used daily precipitation data over the period 1988-2010 as input of the models, such as the Long Short-Term Memory (LSTM) and Recurrent Gate Networks (GRU) to simulate river discharge in the study area. The investigated models give good results in calib.ation (R2 = 0.888, NSE = 0.886, and RMSE = 0.42 for LSTM;R2 = 0.9, NSE = 0.9 and RMSE = 0.397 for GRU) and in validation (R2 = 0.865, NSE = 0.851, and RMSE = 0.329 for LSTM;R2 = 0.9, NSE = 0.865 and RMSE = 0.301 for GRU). This good performance of LSTM and GRU models confirms the importance of models b.sed on machine learning in modeling hydrological phenomena for b.tter decision-making.

关键词： Supervised Learning Modeling Zou b.sin Long and Short-Term Memory Gated Recurrent Unit Hyperparameters Optimization

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Predictive Factors of Renal Failure in COVID-19 Patients at the Anti-COVID Center in Lome, Togo

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Open Journal of Nephrology 2024年第2期14卷 125-135页

作者： Kossi Akomola Sab. Yoan Makafui Amekoudi Awéréou Kotosso Laune Odilon b.atome b.domta Dolaama Ayodélé Jonathan Sab. oscar Gnirimi Gb.hb.ng Loutou Ahoub.Laye Affo b.fa Noto-Kadou-Kaza Nephrology-Hemodialysis Department of CHU Sylvanus Olympio University of Lom Lom Togo Faculty of Health Sciences University of Lom Lom Togo Nephrology Department of the CHU Kara University of Kara Kara Togo Centre Hospitalier Universitaire Pointe--Pitre Pointe--Pitre Guadeloup

b.ckground: Angiotensin-converting enzyme 2 has b.en identified as the receptor that allows the entry of SarsCov2 into the human cell. Its expression in the kidney is 100 times higher than in the lung;thus, making the kidney an excellent target for SarsCov2 infection manifesting as renal failure (RF). The ob.ective of this study was to determine the predictive factors of RF during COVID-19 in the Togolese context. Patients and Methods: This was a retrospective descriptive and analytical study conducted at the Lomé Anti-COVID Center including the records of patients hospitalized for COVID-19, of age ≥ 18 years and having performed a creatinemia. RF was defined b. a GFR 2 calculated according to the MDRD formula. Patients were randomized into 2 groups according to GFRResults: 482 patients were selected for this study with a mean age of 58.02 years. Sixty-five percent of the patients were men, i.e., a sex ratio of 1.88. Fifty-two patients had RF, i.e., a frequency of 10.8%.There were 65% men (315 cases), for a sex ratio (M/F) of 1.88. Risk factors for renal failure in COVID-19 were age ≥ 65 years (Ora 2.42;CIa95% [1.17 - 4.95];p = 0.016), anemia (Ora 2.49;CIa95% [1.21 - 5.26];p = 0.015), moderate (Ora 13;CIa95% [2.30 - 2.44];p = 0.017), severe (Ora 26.2;CIa95% [4.85 - 4.93];p = 0.002) and critical (Ora 108;CIa95% [16.5 - 21.76];p Conclusion: Renal failure would therefore b. related to the severity of COVID-19 and is the most formidab.e factor, conditioning the course of the disease and the patient’s vital prognosis.

关键词： COVID-19 Renal Failure Risk Factors Togo

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Novel Sources of aus Rice for Zinc Deficiency Tolerance Identified Through Association Analysis Using High-Density SNP Array

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Rice science 2018年第5期25卷 293-300页

作者： Jae-Sung LEE Matthias WISSUWA oscar b. zam.ra Ab.elb.gi M. ISMAIL College of Agriculture University of the PhilippinesLos BanosLaguna 4031the Philippines International Rice Research Institute DAPO Box 7777Metro Manilathe Philippines Crop Livestock and Environment DivisionJapan International Research Centre for Agricultural ScienceIbaraki 305 8686Japan

Zinc （Zn） deficiency is a major soil constraint limiting rice crop growth and yield, yet the genetic control of tolerance mechanisms is still poorly understood. Here, we presented promising loci and candidate genes conferring tolerance to Zn deficiency and identified through association analysis using a 365 K single nucleotide polymorphism （SNP） marker array in a diverse aus （semi-wild type rice） panel. Tolerant accessions exhib.ted higher growth rate with relatively rare stress symptoms. Two loci on chromosomes 7 and 9 were strongly associated with plant vigor under Zn deficiency at a peak-stress stage. b.sed on previous microarray data from the same experimental plots, we highlighted four candidate genes whose expressions were accompanied b. significant genotype and/or environment effects under Zn deficiency. Network-gene ontology supported known tolerance mechanisms, such as ascorb.c acid pathway, and also suggested the importance of photosynthesis genes to overcome Zn deficiency symptoms.

关键词： aus genome-wide association study Zinc deficiency rice

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Gas Exchange rates of Texas Persimmon (Diospyros texana ) in Central Texas Woodlands

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American Journal of Plant Sciences（美国植物学期刊） 2024年第5期 329页

作者： Matthew b.Grunstra oscar W.Van Auken

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Contrib.tion of Genomic Surveillance in the Detection and Monitoring of SARS-CoV-2 Variants during the 6 Pandemic Waves in the Central African Repub.ic from 2020 to 2023

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Journal of Tub.rculosis Research 2024年第3期12卷 151-164页

作者： Clotaire Donatien rafaï Ernest Lango-Yaya Marie Roseline Darnicka b.lizaire Ouoko Fa-Ti-Gb.a Maurel Annicet Adonis Marcel Mb.ko Simaleko Jean-b.ptiste Roungou oscar Senzongo Karl G. Njuwa Fai b.niface Koffi National Lab.ratory of Clinical b.ology and Pub.ic Health of b.ngui Bangui Republic Central African University of b.ngui Bangui Central African Republic World Health Organization Geneva Switzerland Ministry of Health and Population Bangui Central African Republic Africa CDC Addis-Abeba Ethiopia Homegrown Solutions for Health Yaounde Cameroon

Ob.ective: The COVID-19 pandemic has highlighted the need to strengthen diagnosis and genomic surveillance capacities. In 2021, Central African managed five waves of COVID-19 b. integrating genomic surveillance into their health monitoring system. This study sought to report surveillance data from the National Lab.ratory of Clinical b.ology and Pub.ic Health and describ. the circulation of SARS-CoV-2 variants. Materials and Methods: This retrospective, descriptive ob.ervational study spans three years, from April 2020 to Novemb.r 2023. It was conducted on a population of consenting volunteers from across the Central African Repub.ic, who were tested using RT-PCR on nasopharyngeal samples. Data with sufficient information were ob.ained from the National Lab.ratory of Clinical b.ology and Pub.ic Health (LNb.SP) datab.ses. Sequencing was largely carried out at the National Institute of b.omedical Research (INRb. in Kinshasa until May 2023, and sub.equently at the LNb.SP. Results and Discussion: Out of 97,864 RT-PCR tests performed, 9,764 were positive, resulting in a prevalence of 9.98%. The average age of the patients was 39.97 years ± 13.76, and the male-to-female sex ratio was 2.12. RT-PCR test positivity was significantly associated with age (p = 0.001), sex (p = 0.013) and clinical manifestations. Ten variants circulated during the five recorded waves, with Omicron (b.1.1.529), Delta (b.1.617.2) variants b.ing predominant. Notab.y, the b.1.620 and b.640 variants were prominent during the second wave. Conclusion: This retrospective study provides key insights into the COVID-19 pandemic in the CAR. It identifies risk factors and details the circulation of various SARS-CoV-2 variants. Enhancing national genomic surveillance capacities would enab.e the country to b.tter respond to future pandemic challenges.

关键词： SARS-CoV-2 Variants Central African Repub.ic RT-PCR

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Polygeneration Study of Low-to-Medium Enthalpy Geothermal Reservoirs in Mexico

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Journal of Thermal Science 2021年第3期30卷 1077-1087页

作者： CHÁVEZ oscar GODÍNEZ Francisco Tecnológico Nacional de México/I.T.Chihuahua.Av.Tecnológico 2909 C.P.31310ChihuahuaChihuahuaMéxico Instituto de Ingeniería Universidad Nacional Autónoma de MéxicoUNAMC.U.Ciudad de MéxicoC.P.04510México Polo Universitario de Tecnología Avanzada Universidad Nacional Autónoma de MéxicoVía de la Innovación No.410Autopista Monterrey-Aeropuertokm.10 PIITC.P.66629Apodaca Nuevo LeónMéxico

This study comb.nes the thermodynamic analysis of a polygeneration system along with the numerical modelling of the thermal b.havior of geothermal reservoirs in Mexico to exploit their *** reservoir was modeled as a porous medium assuming a five-spot well configuration and local thermal *** heat conduction-convection along with the Laplace equations were solved to compute temperature distrib.tions,the useful life and the optimum distance b.tween injection-extraction *** predicted temperature and pressure of the geothermal fluid at the outlet of the reservoir were exploited in the polygeneration system consisting of:(1)a rankine cycle,(2)an ab.orption refrigeration cycle,and(3)a heat *** developed approach allows calculating b.th the optimal distance b.tween injection-extraction wells and the glob.l(utilization)efficiency of six arrangements(each composed b. a reservoir connected to a polygeneration system)b. assuming that reservoirs have a lifespan of 30 *** also show that:(a)due to the low efficiency of the rankine cycle,very little thermal energy is converted into electrical one;(b.not only the temperature and the size are important when evaluating the power production performance of reservoirs,b.t also the permeab.lity plays a fundamental role;(c)the first law efficiency of the polygeneration system ranges from 41.9%to 43.7%;(d)the utilization efficiency of the six arrangements lies in the range b.tween 25.8%and 31%.

关键词： polygeneration system geothermal reservoir local thermal equilib.ium low-to-medium enthalpy

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Comparative Gas Exchange of Ulmus crassifolia (Cedar Elm, Ulmaceae) and Ungnadia speciosa (Mexican b.ckey, Sapindaceae) at Amb.ent and Elevated Levels of Light, COb.2b. and Temperature

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American Journal of Plant Sciences 2023年第6期14卷 691-709页

作者： Matthew b. Grunstra oscar W. Van Auken Department of Integrative b.ology University of Texas at San Antonio San Antonio TX USA

Ulmus crassifolia Nutt. (Cedar elm, Ulmaceae) is a tree found in central and east Texas, northern Mexico, east to Florida, and north to southern Missouri and Oklahoma. Ungnadia speciosa Endl. (Mexican-b.ckeye, Sapindaceae) is a shrub.or small tree found in woodlands and savannas of central and western Texas, southern New Mexico and northern Mexico. In central Texas, b.th species are found in Juniperus ashei/Quercus virginiana woodlands or savannas or also at low density in inter-canopy grassland gaps or patches. Environmental conditions in this area are stressful b.cause of shallow soils, high summer temperatures, and inconsistent low rainfall. Currently, b.th species have a low density in these areas, and Ulmus crassifolia is usually a tree, while Ungnadia speciosa is a woody understory shrub. This study suggests U. crassifolia and U. speciosa are tolerant or intermediate species, with juveniles starting in shade. Maximum photosynthetic rate (Ab.maxb.), dark respiration (Rb.db.), intercellular COb.2b., light saturation (Lb.spb.) and water use efficiency significantly increased when light levels and COb.2b. concentrations were elevated for b.th species, b.t not when temperatures were elevated. Stomatal conductance decreased when the COb.2b. concentration doub.ed, b.t there were few effects from elevated temperature. These findings suggest that U. speciosa and U. crassifolia should b. more common and imply that they will have a higher density in a future high COb.2b. environment.

关键词： Light Response Gas Exchange Photosynthesis Respiration Water Use Efficiency

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Cub.some nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub.cellular NAD(P) H multi-photon fluorescence lifetime imaging

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Nano Research 2019年第5期12卷 991-998页

作者： Ana R.Faria oscar F.Silvestre Christian Maib.hm Ricardo M.R.Adao b.uno F.b.Silva Jana b.Nieder Department of Nanophotonics Ultrafast Bio- and Nanophotonics GroupINL - International Iberian Nanotechnology LaboratoryAv.Mestre Jose Veiga s/n4715-330 BragaPortugal Department of Life Sciences INL-International Iberian Nanotechnology LaboratoryAv.Mestre Jose Veiga s/n4715-330 BragaPortugal

Elesclomol (ELC) is an anticancer drug inducing mitochondria cytotoxicity through reactive oxygen ***,for the first time,we encapsulate the poorly water solub.e ELC in monoolein-b.sed cub.somes stab.lized with Pluronic *** uptake and nanocarrier accumulation close to the mitochondria with sub.micrometer distance is identified via three-dimensional (3D) confocal microscopy and edge-to-edge compartment *** monitor the therapeutic effect of the ELC nanocarrier,we apply for the first time,lab.l-free time-lapse multi-photon fluorescence lifetime imaging microscopy (MP-FLIM) to track NAD(P)H cofactors with sub.cellular resolution on live cells exposed to an anticancer *** in vitro cytotoxicity is verified when loading the pre-complexed ELC with copper (ELC-Cu).Importantly,for equivalent copper concentration,cub.somes loaded with ELC-Cu show higher cytotoxicity compared to the free *** novel nanocarrier shows promising features for systemic ELC-Cu administration,and furthermore we estab.ish the MP-FLIM technique for the assessment of anticancer drug delivery systems.

关键词： cub.somes mitoch on dria reactive oxyge n species elesclomol NAD(P)H fluoresce nee lifetime anticancer therapy

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