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New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1699-1700页

作者： Seyed Mojtaba Hosseini Soheila karimi-Abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada Manitoba Multiple Sclerosis Research Center WinnipegMBCanada Children Hospital Research Institute of Manitoba WinnipegMBCanada

Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord undergoes a cascade of secondary injury mechanisms that are driven by disruption of the blood-spinal cord ba rrier,vascula r inju ry,glial reactivity,neu roinfla mmation,oxidative stress,lipid peroxidation,and glutamate excitotoxicity that culminate in neuronal and oligodendroglial cell death,demyelination,and axonal damage(Alizadeh et al.,2019).To achieve a meaningful functional recovery after SCI,regeneration of new neurons and oligodendrocytes and their successful growth and integration within the neural network are critical steps for reconstructing the damaged spinal cord tissue (Fischer et al.,2020).

关键词： peroxidation Fischer injury

Soil evolution along an alluvial-loess transect in the Herat Plain,western Afghanistan

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Journal of Arid Land 2022年第11期14卷 1317-1330页

作者： Farsila MAHMOUDIAN Alireza karimi omid BAYAT Department of Soil Science Faculty of AgricultureHerat UniversityHerat 3001-272806Afghanistan Department of Soil Science Faculty of AgricultureFerdowsi University of MashhadMashhad ***Iran

Afghanistan is located in the Eurasian loess belt,however,there is little information on the soils in the *** has covered the Herat Plain in western Herat City,*** the diversity of landform and parent material,there is no information on the soil and landform evolution in this *** objectives of this study were to identify the soils along a transect of different landforms in the Herat Plain and determine the role of geomorphic processes on the soil and landform *** pedons from an alluvial fan,the depression between alluvial fan and piedmont plain,saline and non-saline piedmont plains,and the flood plain of the Hariroud River,were ***,the physical-chemical properties,mineralogy,and micromorphology of the samples were *** showed that the soil parent material in the piedmont plain is loess,whereas,in the flood plain it is a combination of loess and river alluvial ***,lessivage,salinization,and gleization are the most important pedogenic *** calcification and lessivage appear to be the result of a wetter climate during the late Quaternary,whereas the present topography causes the gleization and *** coatings on carbonate nodules and iron nodules are abundant pedofeatures in the Btk(argillic-calcic)*** oxides nodules are common in the soils of the flood *** formation of palygorskite in both alluvial-and loess-derived soils implies the onset of aridity and the trend of increase in environmental aridity in the *** seems that after the formation of a well developed paleosol on the alluvial fan in a more humid climate in the past,the piedmont plain has been covered by loess deposits,and the calcification,gleization,and salinization cause the formation of weakly developed surficial *** study highlights the role of the late Quaternary climatic changes on the evolution of landforms and soils in western Afghanistan.

关键词： alluvial fan loess-derived soils paleosol gleization Hariroud River

Antiviral Activity of Medicinal Plants against Human Coronavirus: a systematic scoping review of in vitro and in vivo experimentations

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Journal of Traditional Chinese Medicine 2022年第3期42卷 332-343页

作者： Parva Namiranian omid Sadatpour Sadegh Azimzadeh Jamalkandi Mohammad Hossein Ayati Mehrdad karimi Department of Traditional Medicine School of Persian MedicineTehran University of Medical SciencesTehranIran Department of Immunology School of MedicineTehran University of Medical SciencesTehranIran Chemical Injuries Research Center Systems Biology and Poisonings InstituteBaqiyatallah University of Medical SciencesTehranIran

OBJECTIVE:To investigate the in vitro and in vivo studies of natural compounds and medicinal plants with anti-coronavirus ***:A systematic review was performed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Animal Research:Reporting of in vivo experiments guidelines to find data for medicinal plants and natural products effective against human coronaviruses in in vitro or in vivo *** published up to September 6,2020 were ***(in vitro or in vivo)reporting the effect of medicinal plants and natural products or their derivatives on human coronavirus were included RESULTS:Promising anti-coronavirus effects are seen with different herbal compounds like some diterpenoids,sesquiterpenoids,and three compounds in tea with 3 CLpro inhibiting effect of Severe Acute Respiratory Syndrome Coronavirus(SARS-Co V);Hirsutenone,Six cinnamic amides and bavachinin are PLpro inhibitors and Tanshinones are active on both 3 CLpro and *** flavonoid compounds of Citrus fruits act on Immunoregulation and target angiotensin-converting enzyme 2 which is used by SARS-COV for *** helicase is possibly inhibited by two compounds myricetin and ***:This review shows that complementary medicine have the potential for new drug discovery against *** research is needed before definitive conclusions can be made concerning the safety and efficacy of the use of these medicinal plants.

关键词： Coronavirus medicine,Persian medicine,Chinese traditional plants,medicinal new drug discovery

Modelling the probability of presence of Aedes aegypti and Aedes albopictus in Iran until 2070

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Asian Pacific Journal of Tropical Medicine 2023年第1期16卷 16-25页

作者： Mohammad Mehdi Sedaghat Faramarz Bozorg omid Mohammad karimi Sajjad Haghi Ahmad Ali Hanafi-Bojd Department of Vector Biology&Control School of Public HealthTehran University of Medical SciencesTehranIran Department of GIS Faculty of Geodesy and Geomatics EngineeringK.N.Toosi University of TechnologyTehranIran Zoonoses Research Center Tehran University of Medical SciencesTehranIran

Objective:To determine the suitable ecological habitats of Aedes(Ae.)aegypti and *** in Iran due to climate change by the ***:All data relating to the spatial distribution of *** and *** worldwide,which indicated the geographical coordinates of the collection sites of these mosquitoes,were extracted from online scientific websites and entered into an Excel *** effect of climatic and environmental variables on these mosquitoes was evaluated using the MaxEnt model in the current and future climatic conditions in the 2030s,2050s,and ***:The most suitable areas for the establishment of *** are located in the southern and northern coastal areas of Iran,based on the model *** modelling result for suitable ecological niches of *** shows that in the current climatic conditions,the southern half of Iran from east to west,and parts of the northern coasts are prone to the presence of this *** the future,some regions,such as Gilan and Golestan provinces,will have more potential to exist/establish ***,according to the different climate change scenarios,suitable habitats for this species will gradually change to the northwest and west of the *** temperature of the wettest season of the year(Bio8)and average annual temperature(Bio1)were the most effective factors in predicting the model for *** and ***,***:It is required to focus on entomological studies using different collection methods in the vulnerable areas of *** future modelling results can also be used for long-term planning to prevent the entry and establishment of these invasive Aedes vectors in the country.

关键词： Aedes aegypti Aedes albopictus Dengue fever Chikungunya Ecological Niche Modeling Climate change

Electrocatalytic performance of Pt/Ru/Sn/W fullerene electrode for methanol oxidation in direct methanol fuel cell

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燃料化学学报 2013年第1期41卷 91-95页

作者： Mohammad karimi Forouzan Aboufazeli Hamid Reza Lotfi Zadeh Zhad omid Sadeghi Ezzatollah Najafi Department of Chemistry Shahr-e-Rey BranchIslamic Azad University

In this work,fullerene was modified by platinum,ruthenium,tin and tungsten *** material was characterized by XRD,ICP-OES and TEM *** average nanoparticle size on fullerene was 5-8 *** application of this material was investigated as a catalyst for methanol oxidation in direct methanol fuel cell.A glassy carbon electrode was modified by Pt/Ru/Sn/W fullerene and electrocatalytic activity of the electrode toward methanol oxidation in basic medium has been demonstrated and investigated using cyclic *** catalyst showed good reactivity for methanol oxidation.

关键词：摘要编辑部编辑工作读者

The contribution of steel wallposts to out-of-plane behavior of non-structural masonry walls

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Earthquake Engineering and Engineering Vibration 2023年第1期22卷 243-262页

作者： Fooad karimi Ghaleh Jough Department of Civil Engineering Final International UniversityKyreniaNorth Cyprusvia Mersin 10 Turkey

For years,non-structural masonry walls have received little attention by code developers and professional ***,significant efforts have been made to shed more light on out-of-plane(OOP)behavior of non-structural masonry *** updated provisions of the Iranian seismic code,bed joint reinforcements(BJRs)and steel wallposts have been suggested for *** are horizontal reinforcements;steel wallposts are vertical truss-like elements intended to provide additional OOP restraints for a *** contribution of BJRs has previously been investigated by the *** study is devoted to investigating the contribution of steel wallposts to the OOP behavior of non-structural masonry *** pre-validated 3D finite element(FE)models,the OOP behavior of 180 non-structural masonry walls with varying configurations and details are *** OOP pressure-displacement curve,ultimate strength,the response modification factor,and the cracking pattern are among the results presented in this *** is found that steel wallposts,especially those with higher rigidity,can improve the OOP strength of the *** contribution of wallposts in the case of shorter length walls and walls with an opening are more *** also indicate that masonry walls with wallpost generally have smaller modification factors compared to similar walls without wallpost.

关键词： masonry wall wallpost wind post bed joint reinforcement non-structural masonry wall out-of-plane behavior

Deformed photon-added entangled squeezed vacuum and one-photon states: Entanglement, polarization, and nonclassical properties

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Chinese Physics B 2016年第4期25卷 47-56页

作者： A karimi M K Tavassoly Atomic and Molecular Group Faculty of Physics Yazd University Physics Group Islamic Azad University of Abadeh The Laboratory of Quantum Information Processing Yazd University

In this paper, after a brief review on the entangled squeezed states, we produce a new class of the continuous-variable- type entangled states, namely, deformed photon-added entangled squeezed states. These states are obtained via the iterated action of the f-deformed creation operator A = f（n）a＋ on the entangled squeezed states. In the continuation, by studying the criteria such as the degree of entanglement, quantum polarization as well as sub-Poissonian photon statistics, the two- mode correlation function, one-mode and two-mode squeezing, we investigate the nonclassical behaviors of the introduced states in detail by choosing a particular f-deformation function. It is revealed that the above-mentioned physical properties can be affected and so may be tuned by justifying the excitation number, after choosing a nonlinearity function. Finally, to generate the introduced states, we propose a theoretical scheme using the nonlinear Jaynes-Cummings model.

关键词： squeezed states deformed photon-added entangled states entanglement quantum polarization

Characterization of mechanothermally processed nanostructured ZnO

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International Journal of Minerals,Metallurgy and Materials 2016年第5期23卷 588-594页

作者： Saeed karimi Abolghasem Ataie School of Metallurgy and Materials Engineering College of Engineering University of Tehran

In this paper, the Taguchi method with an L9（34） orthogonal array was used as experimental design to determine the optimum conditions for preparing ZnO nanoparticles via a mechanothermal route. ZnSO4·H20 and NaECO3 were used as starting materials. The effects of milling time, NaECO3/ZnSO·H20 molar ratio, and ball-to-powder mass ratio （BPR） on the bandgap （Eg） of ZnO nanoparticles were inves- tigated. The ranges of the investigated experimental conditions were 5-15 h for the milling time （t）, 1.0-1.2 for the Na2COa/ZnSO4·H20 mo- lar ratio （M）, and 10-30 for BPR. The milling time and BPR exhibited significant effects; an increase in milling time reduced the bandgap. The optimum conditions from this study were t3 = 15 h, M1 = l, and BPR2 = 20. Only two significant factors （t3, 15 h; BPR2, 20） were used to estimate the performance at the optimum conditions. The calculated bandgap was 3.12 eV, in reasonable agreement with the experimental results obtained under the optimized conditions.

关键词： mechanothermal treatment synthesis nanoparticles zinc oxide Taguchi methods

Microstructural evolution,mechanical properties,and corrosion resistance of a heat-treated Mg alloy for the bio-medical application

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Journal of Magnesium and Alloys 2019年第1期7卷 80-89页

作者： Mohammad Janbozorgi Kimia karimi Taheri Ali karimi Taheri Department of Materials Science and Engineering Sharif University of TechnologyAzadi Ave.TehranIran School of Medicine Shahid Beheshti University of Medical ScienceTehranIran

During the recent years,some Mg based alloys have extensively been considered as a new generation of degradable and absorbable bio-medical *** this work,the Mg-2Zn-1Gd-1Ca(wt%)alloy as a new metallic bio-material was produced by the casting process followed by the heat *** samples of the alloy were solution treated at temperatures of 500,550,and 600°C and then quench aged at temperatures of 125,150,and 175°*** results of SEM-EDS examinations indicated that the alloy microstructure consists ofα-Mg matrix and the Ca_(2)Mg_(6)Zn_(3)and Mg_(3)Gd_(2)Zn_(3)secondary *** regard to the results of Vickers hardness test,the temperatures of 500°C and 150°C were selected as the optimum solutionizing and aging temperatures,***,the dissolution of casting precipitates and production of lattice distortion occurring after the solution treatment led to the reduction in ultimate shear strength up to 21%.But,the precipitation hardening and morphological changes taking place during the aging treatment improved the ultimate shear strength up to 32%.Furthermore,the results of electro-chemical and weight-loss measurements in a simulated body fluid indicated that the heat-treated alloy is a promising candidate for the Mg based alloys recently considered for the bio-medical applications.

关键词： Mg alloys Bio-medical applications Microstructural evolution Mechanical properties Corrosion resistance