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Airway pressure release ventilation forin-vivodonor lung management and lung transplant outcomes

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中华胸部外科电子杂志 2022年第2期9卷 65-74页

作者： Sreeja Biswas Roy Deepika Razia Ashwini Arjuna Paul Kang Michael t.olson Ross M.Bremner Michael A.Smith Rajat Walia Norton thoracic Institute St.Joseph’s Hospital and Medical CenterCenter for Thoracic Disease and TransplantationPhoenixAZUSA Creighton University School of Medicine-Phoenix Regional Campus PhoenixAZUSA University of Arizona College of Public Health PhoenixAZUSA University of Arizona College of Medicine-Phoenix Campus PhoenixAZUSA

Background:Airway pressure release ventilation(APRV)can be used for cadaveric donor lung *** elevates PaO_(2)in donor lungs;however,reported outcomes in recipients with APRVmanaged donor lungs are ***:We retrospectively reviewed patients who underwent lung transplantation(Ltx)from 2012 to 2013 and divided them into two groups based on mode of ventilation used during donor management and organ extraction(A:non-APRV;B:APRV).Kaplan-Meier method and multivariate Cox regression were used for ***:We found 126 Ltx recipients(LtxRs);9 were excluded for use of portable ventilation perfusion *** the remaining 117 patients,81(69%)were in Group A;36(31%)were in Group *** LtxR characteristics(age,sex,lung allocation score,endstage lung disease type)were comparable between *** for Group B were older(P=0.03)and had higher body mass index(BMI)(Pth from chest trauma(P=0.008),longer ventilation duration after brain death(Pt PaO_(2)/FiO_(2)ratios(Pt-Ltx duration of mechanical ventilation,hospital stay,and median survival were similar in both *** of death was comparable between the two groups at the end of follow-up(HR=1.42;95%CI:0.57-3.56;P=0.45).Conclusions:APRV is a safe and effective pre-Ltx donor lung management ***-and long-term survival outcomes were comparable in Ltx recipients,irrespective of donor ventilation *** may help recruit lungs from older donors with higher BMI who die from chest trauma and have anticipated longer ventilation duration.

关键词： Lung transplantation donor lungs airway pressure release ventilation(APRV) outcomes

超人类主义的形而上学--对人工智能假设的批判

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阅江学刊 2022年第4期14卷 107-119,174页

作者： [英]埃里克·奥尔森王世鹏(译) 罗岩超(译) 谢菲尔德大学哲学系华中师范大学马克思主义学院哲学系

超人类主义旨在借助技术使人类得到增强,以摆脱人类身体的局限。超人类主义者想要通过“上传”的方式将我们从人类躯壳所强加的束缚中解放出来,他们所说的“上传”是从大脑中提取信息,将信息传输至计算机,运用这些信息在计算机中创造一... 详细信息

超人类主义旨在借助技术使人类得到增强,以摆脱人类身体的局限。超人类主义者想要通过“上传”的方式将我们从人类躯壳所强加的束缚中解放出来,他们所说的“上传”是从大脑中提取信息,将信息传输至计算机,运用这些信息在计算机中创造一个纯粹的电子人。这就是要把我们从人类身体转移到计算机之中。它预设,只凭借信息的传输就可以将一个人完全转移到计算机之中,并使之作为电子人继续存在。“上传”既要包含对人工智能假设的辩护,又要在此基础上完成对人格同一性假设的辩护。但是,超人类主义者基于“宽心理标准”为跨时间人格同一性假设所做的辩护,却难以摆脱“分支难题”和“复制难题”的困扰。而且,我们完全由物质组成。“上传”只有信息的连续性而没有物质的连续性,并不能把一件物质的东西从一个地方转移到另一个地方,因而我们无法“上传”,“上传”在形而上学上完全不可能。把人归结为信息进而否认我们是物质的所谓“样式论”,同样难以规避形而上学的难题。尽管我们无法通过“上传”转移到计算机中,但是创造出在心理上优于我们自身,且能从人类局限性中解脱出来的纯粹电子人却是有可能的。

关键词：人工智能德里克·帕菲特人格同一性 “上传”

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睡眠呼吸暂停和心肺功能与长期主要心血管事件的关系

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中华高血压杂志(中英文) 2021年第6期29卷 599-599页

作者： Barillas-Lara MI Medina-Inojosa JR Kolla BP Smith JR Bonikowske AR Allison tG olson t Lopez-Jimenez F Somers VK Caples SM Mansukhani MP 刘青练桂丽

确定睡眠呼吸紊乱(sleep-disordered breathing, SDB)合并心肺适能减退时发生长期主要不良心血管事件(major adverse cardiovascular events, MACE)的风险。方法:研究者纳入2005年1月1日至2010年1月1日之间接受症状限制性心肺运动试验...

确定睡眠呼吸紊乱(sleep-disordered breathing, SDB)合并心肺适能减退时发生长期主要不良心血管事件(major adverse cardiovascular events, MACE)的风险。方法:研究者纳入2005年1月1日至2010年1月1日之间接受症状限制性心肺运动试验的连续患者,随后在6个月内进行首次诊断性多导睡眠监测。根据存在中度至重度SDB(呼吸暂停低通气指数≥15次/h)

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Structural and Optical Properties and Emerging Applications of Metal Nanomaterials

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Journal of Materials Science & technology 2008年第4期24卷 433-446页

作者： tammg Y.olson Department of Chemistry and Biochemistry University of CaliforniaSanta CruzCA 95064USA

Nanomaterials possess intriguing optical properties that depend sensitively on size, shape, and material content of the structures. Controlling such structural characteristics of the nanostructures allows the tailoring of their physical and chemical properties, e.g. optical, electronic, and catalytic, to achieve what is desired lot specific applications of interest. this review will cover the development of various shapes for silver and gold nanomaterials with emphasis on their relation to optical properties. Examples of various modern synthetic methods and characterization techniques are highlighted. the influence of the metal nanomaterial＇s shape and optical absorption on surface enhanced Raman scattering （SERS） and a final note on new emerging applications of metal nanostructures are also discussed.

关键词： Nanomaterial Metal nanostructure Optical properties Size and shape effect

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Cybermaterials: materials by design and accelerated insertion of materials

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npj Computational Materials 2016年第1期2卷 233-246页

作者： Wei Xiong Gregory B olson Department of Materials Science and Engineering Northwestern UniversityEvanstonILUSA Questek Innovations LLC EvanstonILUSA

Cybermaterials innovation entails an integration of Materials by Design and accelerated insertion of materials(AIM),which transfers studio ideation into industrial *** assembling a hierarchical architecture of integrated computational materials design(ICMD)based on materials genomic fundamental databases,the ICMD mechanistic design models accelerate *** here review progress in the development of linkage models of the process-structure–property-performance paradigm,as well as related design accelerating *** the materials development capability based on phase-level structural control requires more fundamental investment at the level of the Materials Genome,with focus on improving applicable parametric design models and constructing high-quality *** opportunities in materials genomic research serving both Materials by Design and AIM are addressed.

关键词： insertion linkage constructing

Numerical prediction of fiber motion in a branching channel flow of fiber suspensions

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Acta Mechanica Sinica 2005年第4期21卷 322-329页

作者： Jianzhong Lin Shanliang Zhang James A. olson Department of Mechanics The State Key Laboratory of Fluid Power Transmission and ControlZhejiang University: Ha ngzhou 310027 China Department of Mechanical Engineering Pulp and Paper CenterThe University of British ColumbiaVancouver BC Canada V6T IZ4

Fiber orientation and dispersion in the dilute fiber suspension that flows through a t-shaped branching channel are simulated numerically based on the slender-body theory. the simulated results are consistent qualitatively with the experimental data available in the literature. the results show that the spatial distribution of fibers is dependent on the fiber aspect ratio, but has no relation with the volume fraction of fiber. the content ratio of fibers near the upper wall increases monotonically with an increasing Re number, and the situation is reverse for the region near the bottom wall. the orientation of fibers depends on Re number, however, the function of fiber volume fraction and aspect ratio is negligible. the fibers near the wall and in the central region of the channel align along the flow direction at all times, but the fibers in the other parts of the channel tend to align along the flow direction only in the downstream region.

关键词： Fiber suspension Distribution Orientation ,Numerical simulation Branching flow

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Phosphinic Acid/Nal Mediated Reductive Cyclization Approach for Accessing the L-1-Deoxynojirimycin Using a two-Component three-Centered (2C3C) Ugi type Reaction

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Chinese Journal of Chemistry 2021年第6期39卷 1503-1510页

作者： Chandra S Azad Pratibha Shukla Mark A olson Anudeep K Narula Institute for Molecular Design and Synthesis School of Pharmaceutical Science&TechnologyHealth Science PlatformTianjin University92 Weijin RoadNankai DistrictTianjin 300072China "Hygeia" Centre of Excellence in Pharmaceutical SciencesGuru Gobind Singh Indraprostho UniversitySector 16-CDwarkaNew Delhi 110078India Department of Chemistry Northwestern University2145 Sheridan RoodEvanstonIL 60208USA

A catalytic two-component three-centered(2C3C)Ugi-type reaction was developed for the synthesis of L-1-deoxynojirimycin(DNJ)isomers using a chiron *** new and quite mild catalytic system,comprised of phenylphosphinic ... 详细信息

关键词： Azasugars Multicomponent reactions Nitrilium ion Isocyanide Reductive cyclization

Evaluating provincial-level employment challenge during the coal transition in China

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Advances in Climate Change Research 2022年第5期13卷 729-737页

作者： Caitlin HAMILtON Jiawei SONG Ryna CUI Colin olson Diyang CUI Center for Global Sustainability School of Public PolicyUniversity of MarylandCollege Park 20742USA

As China works to move away from coal in its energy system as a critical strategy to achieve carbon neutrality before 2060,there are several challenges which will affect the coal *** challenge that has not been fully explored is the impact on coal *** are millions of people employed in various sectors along the coal supply chain,including mining,processing,transport,and power *** this study,we developed a framework to understand the magnitude and characteristics of the employment challenges associated with the coal transition across ***,the magnitude and characteristics of the challenges are evaluated from multiple dimensions,including existing coal sector employment,coal production,coal consumption,GDP contribution from the coal industry,and coal mining productivity,to explore how the transition of the coal industry will likely affect different *** results showed that provinces with large total coal employment today are often those with high coal production and consumption,high GDP contribution from the coal industry,and low productivity of coal *** found that employment impacts of a coal transition will not be equally distributed in China,as both the magnitude and characteristics of the employment challenges vary substantially across all *** is therefore important to develop a tailored strategy to tackle specific needs for each province.

关键词： Coal transition Just transition Coal employment Province China

the role of whole brain radiation therapy in the management of newly diagnosed brain metastases： a systematic review and evidence-based clinical practice guideline

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中国神经肿瘤杂志 2010年第1期8卷 57-57页

作者： Gaspar LE Mehta MP Patchell RA Burri SH Robinson PD Morris RE Ammirati M Andrews DW Asher AL Cobbs CS Kondziolka D Linskey ME Loeffler JS McDermott M Mikkelsen t olson JJ Paleologos NA Ryken tC Kalkanis SN. Department of Radiation Oncology University of Colorado-Denver Denver CO USA.