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Successful treatment of tubulointerstitial nephritis in immunoglobulin G4-related disease with rituximab: A case report

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World Journal of Clinical Cases 2019年第16期7卷 2309-2315页

作者： Eray Eroglu Murat Hayri Sipahioglu Soner Senel Sule Ketenci Ertas Seyma Savas Figen Ozturk Ismail Kocyigit Bulent Tokgoz oktay oymak Division of Nephrology Department of Internal MedicineErciyes University School of MedicineKayseri 38039Turkey Division of Rheumatology Department of Internal MedicineErciyes University School of MedicineKayseri 38039Turkey Department of Internal Medicine Erciyes University School of MedicineKayseri 38039Turkey Department of Pathology Erciyes University School of MedicineKayseri 38039Turkey

BACKGROUND Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition that consisted of disorders that share particular clinical,serologic and pathologic *** common presentation of disease includes tumor-like swelling of involved organs and the histopathological findings are a lymphoplasmacytic infiltrate enriched with IgG4-positive plasma cells,and a variable degree of fibrosis that has a characteristic "storiform" pattern in biopsy specimens of tumorlike *** presentations of this disease,which often affects more than one organ,include autoimmune pancreatitis,salivary gland disease (sialadenitis),orbital disease and retroperitoneal *** steroid treatment is essential for the treatment of the disease however,other immunosuppressive drugs including cyclophosphamide or rituximab could be an option in resistant *** SUMMARY Herein,we reported a 34-year-old woman whom previously had diagnosed with asthma,rheumatoid arthritis and Sj?gren’s syndrome (SS) referred our nephrology department due to acute kidney failure development at the last rheumatology *** kidney biopsy she has been diagnosed with IgG4-RD and tubuluointerstitial *** had been accepted resistant to steroid,mycophenolate mofetil,methotrexate and azathioprine therapies due to receiving in last two *** refused to receive cyclophosphamide due to potential gonadotoxicity of the ***,rituximab therapy was *** received 1000 mg infusion,15 d apart and 6 mo later it has been administered same *** one year from the last rituximab dose serum creatinine decreased from 4.4 mg/dL to 1.6 mg/dL,erythrocyte sedimentation rate decreased from 109 mm/h to 13 mm/h [reference range (RR) 0-20],and Creactive protein decreased from 55.6 mg/L to 5 mg/L (RR 0–6).All pathologic lymph nodes and masses were also *** Patients with IgG4-RD usually misdiagnosed with rheumatologic diseases including systemic lupus erythem

关键词： Immunoglobulin G4-related disease Tubulointerstitial nephritis Rituximab Case report

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Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis

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World Journal of Clinical Cases 2017年第3期5卷 119-123页

作者： Eray Eroglu Ismail Kocyigit Aydin Unal Murat Hayri Sipahioglu Hulya Akgun Leylagul Kaynar Bulent Tokgoz oktay oymak Division of Ne-phrology Department of Internal MedicineErciyes University School of Medicine Department of Pathology Erciyes University School of Medicine Division of Hematology Department of Internal MedicineErciyes University School of Medicine

Castleman's disease(CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lymphadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.

关键词： Castleman’s disease Amyloidosis Plasma cell Inflammation End stage renal disease

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Influence of Fluoride Content of Artificial Saliva on Metal Release from 17-4 PH Stainless Steel Foam for Dental Implant Applications

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Journal of Materials Science & Technology 2013年第6期29卷 582-588页

作者： Ilven Mutlu Enver oktay Department of Metallurgical and Materials Engineering Istanbul UniversityIstanbulTurkey

Highly porous 17-4 PH stainless steel foam for implant applications was produced by space holder technique. Metal release and weight loss from 17-4 PH stainless steel foams were investigated in fluoride added artificial saliva environment by static immersion test. An inductively coupled plasma-mass spectrometer was employed to measure the concentrations of various metal ions. Effects of fluoride content of artificial saliva on metal release and weight loss from the steel foams were investigated. Effects of immersion time, pH value and process parameters on the weight loss and metal release were determined. Pore morphology, pore size and mechanical properties of the 17-4 PH stainless steel foams were also characterized.

关键词： Metal release Dental implant Metal foam Fluoride Artificial saliva

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Dirac equation for the Hulthén potential within the Yukawa-type tensor interaction

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Chinese Physics B 2013年第1期22卷 68-76页

作者： oktay Aydogdu Elham Maghsoodi Hassan Hassanabadi Department of Physics Mersin University Department of Physics Shahrood University of Technology

Using the Nikiforov-Uvarov （NU） method, pseudospin and spin symmetric solutions of the Dirac equation for the scalar and vector Hulthen potentials with the Yukawa-type tensor potential are obtained for an arbitrary spin-orbit coupling quantum number K. We deduce the energy eigenvalue equations and corresponding upper- and lower-spinor wave functions in both the pseudospin and spin symmetry cases. Numerical results of the energy eigenvalue equations and the upper- and lower-spinor wave functions are presented to show the effects of the external potential and particle mass parameters as well as pseudospin and spin symmetric constants on the bound-state energies and wave functions in the absence and presence of the tensor interaction.

关键词： Dirac equation Hulthen potential and Yukawa potential pseudospin and spin symmetry tensor interaction

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EIGENFUNCTION EXPANSION FOR STURM-LIOUVILLE PROBLEMS WITH TRANSMISSION CONDITIONS AT ONE INTERIOR POINT

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Acta Mathematica Scientia 2015年第3期35卷 639-649页

作者： oktay Sh.MUKHTAROV Kadriye AYDEMIR Institute of Mathematics and Mechanics Azerbaijan National Academy of Sciences Department of Mathematics Faculty of ScienceGaziosmanpasa University

The purpose of this article is to extend some spectral properties of regular Sturm- Liouville problems to the special type discontinuous boundary-value problem, which consists of a Sturm-Liouville equation together with eigenparameter-dependent boundary conditions and two supplementary transmission conditions. We construct the resolvent operator and Green＇s function and prove theorems about expansions in terms of eigenfunctions in modified Hilbert space L2[a, b].

关键词： Boundary-value problems transmission conditions resolvent operator

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Augmented Winter’s method for forecasting under asynchronous seasonalities

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Journal of Management Analytics 2021年第1期8卷 19-35页

作者： oktay Karabag MMurat Fadıloglu School of Economics Erasmus University RotterdamRotterdamThe Netherlands Department of Industrial Engineering American University of the Middle EastEgailaKuwait

The method of Winters(1960)is one of the most well-known forecasting methodologies in *** main reason behind its popularity is that it is easy to implement and can give quite effective and efficient results for practice ***,this method is not capable of capturing a pattern being emerged due to the simultaneous effects of two different asynchronous calendars,such as Gregorian and *** adapt this method in a way that it can deal with such patterns,and study its performance using a real dataset collected from a brewery factory in *** the same data set,we also provide a comparative performance analysis between our model and several forecasting models such as Winter’s(Winters 1960),TBAT(De Livera et al.2011),ETS(Hyndman et al.2002),and ARIMA(Hyndman and Khandakar 2008).The results we obtained reveal that better forecasts can be achieved using the new method when two asynchronous calendars exert their effects on the time-series.

关键词： sales forecasting Ramadan effect asynchronous calendar effects exponential smoothing

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Approximation Properties of Julia Polynomials

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Acta Mathematica Sinica,English Series 2007年第7期23卷 1303-1310页

作者： Daniyal M.ISRAFILOV Burcin oktay Department of Mathematics Faculty of Art and SciencesBalikesir University

Let G be a finite simply connected domain in the complex plane C, bounded by a rectifiable Jordan curve L, and let w = φ0 （z） be the Riemann conformal mapping of G onto D （0, r0）：= {E-mail：：｜｜〈 r0}, normalized by the conditions φ0 （z0） = 0, φ＇0 （z0） = 1.In this work, the rate of approximation of φ0 by the polynomials, defined with the help of the solutions of some extremal problem, in a closed domain G is studied. This rate depends on the geometric properties of the boundary L.

关键词： conformal mapping extremal polynomials bounded boundary rotation Dini-smooth boundary

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A VHDL application for kinematic equation solutions of multi-degree-of-freedom systems

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第12期15卷 1164-1173页

作者： Hüseyin oktay ERKOL Hüseyin DEMíREL Department of Mechatronics Engineering Faculty of Technology Karabük University Department of Electrical and Electronics Engineering Faculty of Engineering Karabük University

As kinematic calculations are complicated, it takes a long time and is difficult to get the desired accurate result with a single processor in real-time motion control of multi-degree-of-freedom(MDOF) systems. Another calculation unit is needed, especially with the increase in the degree of freedom. The main central processing unit(CPU) has additional loads because of numerous motion elements which move independently from each other and their closed-loop controls. The system designed is also complicated because there are many parts and cabling. This paper presents the design and implementation of a hardware that will provide solutions to these problems. It is realized using the Very High Speed Integrated Circuit Hardware Description Language(VHDL) and field-programmable gate array(FPGA). This hardware is designed for a six-legged robot and has been working with servo motors controlled via the serial port. The hardware on FPGA calculates the required joint angles for the feet positions received from the serial port and sends the calculated angels to the servo motors via the serial port. This hardware has a co-processor for the calculation of kinematic equations and can be used together with the equipment that would reduce the electromechanical mess. It is intended to be used as a tool which will accelerate the transition from design to application for robots.

关键词： Multi-degree-of-freedom systems Kinematics Co-processor Serial communication Six-legged robot

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Comparison via Digital Radiography of Radiopacity Levels of Composite Materials with Various Shades and Viscosities

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Journal of Wuhan University of Technology(Materials Science) 2022年第2期37卷 170-176页

作者： Gunce Ozan oktay Yazicioglu Hidir Tatar Sevda Ozel Yildiz Istanbul University Faculty of Dentistry Dept.of Restorative Dentistry Haseki Education and Research Hospital Istanbul University Faculty of Medicine Dept.of Biostatistics

Aim of the present in vitro study is to evaluate the radiopacity levels of composite resins with various shades and viscosity.10 mm×2 mm discs were prepared from 7 condensable and 4 flowable composites(n=10).An aluminum step wedge ranging from 2.0 to 10.0 mm in thickness was placed on the occlusal *** radiographs were taken using a dental X-ray device and radiographic densities of each step of the aluminum wedge and the samples were recorded to the *** readings were taken and means were ***-Way Anova and Tamhane post hoc tests were *** G-eanial Posterior has the highest radiopacity value followed by Filtek Z550,Aelite Flo has the lowest radiopacity *** composites show higher radiopacity and flowable composites with higher filler loadings have superior radiopacity levels to condensable *** and body shades of the composite brands have also statistically significant differences in radiopacity ***,radiopacity level of a composite resin material is not affected by the size of fillers;however,the composition,shape and loading of the fillers can specify the radiodensity.

关键词： radiopacity composite resins digital radiography flowable composites shade

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A new generic open pit mine planning process with risk assessment ability

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International Journal of Coal Science & Technology 2016年第4期3卷 407-417页

作者： Ngoc Luan Mai oktay Erten Erkan Topal Westem Australian School of Mines Curtin University of Technology Bentley WA 6102 Australia Nazarbayev University Astana Kazakhstan

Conventionally, mining industry relies on a deterministic view, where a unique mine plan is determined based on a single resource model. A major shortfall of this approach is the inability to assess the risk caused by the well-known geological uncertainty, i.e. the in situ grade and tonnage variability of the mineral deposit. Despite some recent attempts in developing stochastic mine planning models which have demonstrated promising results, the industry still remains sceptical about this innovative idea. With respect to unbiased linear estimation, kriging is the most popular and reliable deterministic interpolation technique for resource estimation and it appears to remain its popularity in the near future. This paper presents a new systematic framework to quantify the risk of kriging-based mining projects due to the geological uncertainties. Firstly, conditional simulation is implemented to generate a series of equally-probable orebody realisations and these realisations are then compared with the kriged resource model to analyse its geological uncertainty. Secondly, a production schedule over the life of mine is determined based on the kriged resource model. Finally, risk profiles of that production schedule, namely ore and waste tonnage production, blending grade and Net Present Value （NPV）, are constructed using the orebody realisations. The proposed model was applied on a multi-element deposit and the result demonstrates that that the kriging-based mine plan is unlikely to meet the production targets. Especially, the kriging-based mine plan overestimated the expected NPV at a magnitude of 6.70% to 7.34% （135 M$ to 151 M$）. A new multivariate conditional simulation framework was also introduced in this paper to cope with the multivariate nature of the deposit. Although an iron ore deposit is used to prove the concepts, the method can easily be adapted to other kinds of mineral deposits, including surface coal mine.

关键词： Open pit mine planning Geological uncertainty Multivariate conditional simulation Grade/tonnage curves

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