Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis

作     者：Eray Eroglu Ismail Kocyigit Aydin Unal Murat Hayri Sipahioglu Hulya Akgun Leylagul Kaynar Bulent Tokgoz Oktay Oymak 

作者机构：Division of Ne-phrologyDepartment of Internal MedicineErciyes University School of Medicine Department of PathologyErciyes University School of Medicine Division of HematologyDepartment of Internal MedicineErciyes University School of Medicine 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2017年第5卷第3期

页      面：119-123页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Castleman’s disease Amyloidosis Plasma cell Inflammation End stage renal disease 

摘      要：Castleman s disease(CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lymphadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.