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Traditional medicine use during pregnancy and labor in African context:A scoping review

Journal of Integrative Nursing 2023年第1期5卷 66-72页

作者： Modupe Motunrayo ADAMOLEKUN Oluwaseyi Abiodun akpor Olaolorunpo OLORUNFEMI oghenerobor benjamin akpor Department of Nursing Science College of Medicine and Health SciencesAfe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Medical Surgical/Nursing Federal UniversityOye-EkitiEkiti StateNigeria Department of Biological Science Afe Babalola UniversityAdo-EkitiEkiti StateNigeria

Traditional medicine(TM)has been more popular among pregnant women worldwide and has played a significant part in maternal health-care services in many nations.Herbs,herbal preparations,and finished herbal products all contain active substances that are derived from plant parts or other plant components that are thought to have medicinal advantages.To diagnose,prevent,and treat illnesses as well as to enhance general well-being,about 80%of people use a variety of TM,including herbal remedies.A systematic search of Google Scholar and PubMed was performed utilizing an established scoping review framework by Joanna Briggs Institute from January 2012 to December 2022.A consequent title and abstract review of articles published on TM in the African context were completed.Of over 15,000 published studies identified,15 meeting the inclusion criteria were integrated into the following seven categorical themes:prevalence of TM use,source of information on TM use,reasons for use of TM,route of administration,common herbs used in pregnancy and labor,the effect of herbs used in pregnancy and labor,and predictors of use of TM.The studies reviewed were primarily in the context of an African setting on the use of TM regarding herbal medicine.Of all the articles,the highest number of studies was conducted in Zimbabwe.This review shows increased use of TM by women during pregnancy and labor with a reported prevalence rate varying from 12%to 60%.However,a decrease in use in the third trimester of pregnancy was reported.The most frequent source of information on the use of TM was from family and friends,while age,parity,education,and income were factors affecting use.In conclusion,the participants do not often disclose the use of TM during their antenatal attendance and the reason for use was accessibility and cost.Therefore,there is a need for further study on the safety and efficacy of TM use in pregnancy and labor.

关键词： Africa context labor pregnancy traditional medicine

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Practice and patronage of traditional bonesetting in Ondo State,Nigeria

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Journal of Integrative Nursing 2022年第3期4卷 145-150页

作者： Nafiu Fatihudeen OKORO Adeleke Araoye OJO Oluwaseyi Abiodun akpor oghenerobor benjamin akpor Department of Nursing Science Afe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Nursing Adeleke UniversityEde Osun StateNigeria Department of Biological Sciences Afe Babalola UniversityAdo-EkitiEkiti StateNigeria

Objective:This study was carried out to investigate the determinants of the practice and patronage of traditional bonesetting(TBS)in a Local Government Area of Ondo State,Nigeria.Materials and Methods:A descriptive research design approach with purposive sampling technique was used.Data collection was through the use of two set of self-developed structured questionnaire(for bonesetters and clients).The study obtained data from eight traditional bonesetters and fifty-six inpatients receiving treatments in the bonesetters’homes across the study location.Results:Findings from the study showed that the major cause of fractures were road traffic accidents while low cost of treatment was the major influence for patronizing traditional bonesetters.The study also revealed that majority of the traditional bonesetters had little or no formal education.Among the sociodemographic characteristics of the participants,only occupation showed signification relationship with reasons for patronage of TBS homes(χ^(2)=28.164,P=0.036).Conclusion:The patronage of traditional bonesetters may be impossible to eradicate;thus,the study recommends the need for collaboration among traditional bonesetters and modern orthopedic practitioners through recognition and continuous training of the traditional bonesetters on appropriate management and referrals.

关键词： Practice traditional bonesetters traditional bonesetting treatment

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Herbs and management of hypertension:Claims,criticism,and challenges

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中西医结合护理杂志(英文) 2023年第3期5卷 216-222页

作者： Oluwakemi Elizabeth ADEOLA Oluwaseyi Abiodun akpor oghenerobor benjamin akpor Modupe Motunrayo ADAMOLEKUN Olusola Bolaji ADEWALE Department of Nursing Science Afe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Biological Sciences Afe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Chemical Science Afe Babalola UniversityAdo-EkitiEkiti StateNigeria

Hypertension(HTN)is one of the most common chronic diseases affecting over 30%of the adult population globally,with a growing incidence rate.This article aims to identify the commonly used herbs for HTN treatment and examine their claims,criticisms,and challenges.It further aims to provide useful recommendations regarding the use of herbs for HTN treatment.HTN complications,such as coronary heart disease,stroke,peripheral vascular disease,vision impairment,and renal failure can result in morbidity and mortality.The high cost of conventional medications,which sometimes may not even be available or easily accessible with their unfavorable side effects as well as taking more than one pill per day,has led hypertensive patients,particularly those in rural areas,to explore alternative treatments such as herbal therapies.It is crucial to determine the different modes of action,doses,safety,and efficacy of herbal remedies used in combination with conventional medications to improve treatment adherence and enhance patient outcomes.

关键词： Challenges claims criticism herbs hypertension

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Accessible and low-to zero-cost remedy:Traditional medicine use during pregnancy and labor

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Journal of Integrative Nursing 2023年第2期5卷 75-80页

作者： Modupe Motunrayo ADAMOLEKUN Oluwaseyi Abiodun akpor oghenerobor benjamin akpor Oluwakemi Elizabeth ADEOLA Olusola Bolaji ADEWALE Department of Nursing Science Afe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Biological Sciences Afe Babalola UniversityAdo-EkitiEkiti StateNigeria Department of Chemical Sciences Afe Babalola University Ado-EkitiEkiti StateNigeria

Traditional medicine(TM)has played an essential part in maternity services around the world,which has led to increased utilization among pregnant women.Herbs,herbal preparations,and completed herbal products are examples of TMs that contain active substances such as plant parts or other plant components that are thought to have therapeutic advantages.This study review aimed to identify the herbs commonly used,reasons for use,and effect of use,to make adequate recommendations on herbal medicine use as a remedy for pregnancy and labor.Incorporating evidence from reviews,personal correspondence,and diaries,this study demonstrates that about 80%of people used TM such as herbal remedies for sickness diagnosis,prevention,treatment,and promotion of general well‑being.Due to its accessibility,cost,and availability,TM is usually used by expectant mothers.Examples of TM used in pregnancy and labor include honey,aloe,raspberry,jute mallow,and hibiscus leaves.It is important to note that its use in pregnancy and labor can be beneficial or harmful to both mother and child.Lack of standardization,financial risk,lack of safety,and effectiveness are challenges to TM.There is a need of creating awareness of the safe use and effects of TM in pregnancy and labor through the provision of health education programs for women in the community.

关键词： Labor pregnancy remedy traditional medicine

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Determination of antibacterial activity,total phenolic,flavonoid and saponin contents in leaves of Anogeissus leiocarpus(DC.)Guill and Perr

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Journal of Coastal Life Medicine 2016年第4期4卷 310-314页

作者： Theresa Ibibia Edewor oghenerobor benjamin akpor Stephen Olugbemiga Owa Department of Pure and Applied Chemistry Ladoke Akintola University of TechnologyOgbomosoOyo StateNigeria Department of Biological Sciences Landmark UniversityOmu AranKwara StateNigeria

Objective:To ascertain the antibacterial property and quantify the contents of the total phenolics,flavonoids and saponins in leaves of Anogeissus leiocarpus(DC.)Guill and Perr.Methods:Preliminary phytochemical screening was performed by the method described by Harborne in 1999.Kirby-Bauer disc diffusion method was used for assaying the antibacterial activity.Folin-Ciocalteau reagent and aluminium chloride colorimetric methods were employed for the estimation of the total phenolic and flavonoid contents,respectively.Vanillinacetic acid and perchloric acid mixture was employed in the determination of the total saponin content.Results:The preliminary phytochemical screening revealed the presence of glycosides,tannins,flavonoids,saponins,terpenoids and steroids in the methanolic extract while alkaloids were absent.Only steroids were identified in the n-hexane extract.The methanolic leaf extract was active against Pseudomonas aeruginosa,Staphylococcus aureus,Klebsiella pneumoniae,Proteus vulgaris while the n-hexane was inactive.The total phenolic content obtained was(47.75±0.12)mg gallic acid equivalent/mg extract,the total flavonoid content was(121.50±0.11)mg quercetin equivalent/mg extract,while the total saponin content was(63.42±0.15)mg ginsenoside Rb 1 equivalent/mg extract.Conclusions:The leaves of Anogeissus leiocarpus have high contents of saponins and flavonoids.

关键词： Phytochemicals Bacteria Phenolic Flavonoid Saponins Leaves Anogeissus leiocarpus

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Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice

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Journal of Integrative Medicine 2020年第6期18卷 522-529页

作者： Olarewaju M.Oluba oghenerobor B.akpor Feyikemi D.Adebiyi Sunday J.Josiah Olayinka O.Alabi Ayoola O.Shoyombo Augustine O.Olusola Department of Biochemistry Food Safety&Toxicology Research UnitCollege of Pure&Applied SciencesLandmark UniversityOmu-AranKwara State 251101Nigeria Department of Microbiology College of Pure&Applied SciencesLandmark UniversityOmu-AranKwara State 251101Nigeria Department of Chemical Sciences Joseph Ayo Babalola UniversityIkeji-ArakejiOsun State 233121Nigeria Department of Medical Biochemistry College of Basic Medical SciencesIgbinedion UniversityOkadaEdo State 302110Nigeria Department of Animal Science College of Agricultural SciencesLandmark UniversityOmu-AranKwara State 251101Nigeria Department of Biochemistry Adekunle Ajasin UniversityAkungba AkokoOndo State 342111Nigeria

Objective:To understand the protective effects of Ganoderma terpenoid extract(GTE)against Plasmodium berghei-malarial infection in mice,the present study was carried out to evaluate the effects of GTE in combination with chloroquine disulphate(CQ)on erythrocyte-selected inflammatory markers and antioxidant defense status in P.berghei-infected mice.Methods:P.berghei-infected mice were divided into six groups:infected control(IC)group,administered 1 mL Tween 20;GTE100 and GTE250 groups,administered 100 and 250 mg/kg GTE,respectively;GT100+CQ and GT250+CQ groups,co-administered 100 and 250 mg/kg GTE plus 30 mg/kg CQ,respectively;and CQ group,administered 30 mg/kg CQ.A separate group of non-infected mice were given 1 m L Tween 20,and served as a normal control group(NC).Extract and drug were dissolved in Tween20 and administered orally once daily for 12 consecutive days.At the end of the treatment period,mice were anesthetized with chloroform and sacrificed by cervical dislocation.Plasma was prepared from blood obtained from each mouse.Parameters evaluated at the end of the treatment period include parasitemia,red blood cell count,hematocrit,malondialdehyde(MDA),glutathione(GSH),catalase(CAT),glutathione peroxidase(GPx),superoxide dismutase(SOD),tumor necrosis factor-a(TNF-a),and interleukin-10(IL-10).Results:Infected mice treated with a combination of GTE and CQ(GT100+CQ and GT250+CQ groups)showed significantly reduced parasitemia levels(P<0.05)compared to those administered GTE alone as well as IC.Significant improvement in body weight(P<0.05)was also observed in infected mice treated with a combination of GTE and CQ(GT100+CQ and GT250+CQ groups),compared to mice receiving GTE alone(GTE100 and GTE250 groups).Plasma MDA and TNF-a concentrations were significantly lowered,and IL-10 concentration was significantly increased in GT100+CQ and GT250+CQ groups,relative to the IC group(P<0.05).GSH concentration and SOD,CAT and GPx activities were significantly higher in GT100+CQ and GT250+CQ groups compared to the GTE100,GT

关键词： Ganoderma Terpenes Malaria Oxidative stress Antioxidants Anti-inflammatory agents

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