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Serum sIL-2R and LDH as markers for primary central nervous system lymphoma （PCNSL）

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Serum sIL-2R and LDH as markers for primary central nervous ...

Stem cell therapy for erectile dysfunction

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Takamitsu Fujimaki Nahoko Uemiya Kazuhiko MIshima Gohji Fushihara, hiroaki Neki Kohei Fukuoka Tomonari Suzuki Kenji Wakiya, Junichi Adachi Takaaki Yanagisawa Masao Matsutani Ryo Nishikawa Department of Neurosurgery Saitama Medical University Hospital Department of Neuro-oncology Saitama Medical University International Medical Center Moroyama-machi Saitama Japan

＜正＞Introduction : Serum markers for lymphoproliferative diseases includes soluble IL-2 receptor alpha（sIL-2R）, Lactate dehydrogenase （LDH） and thymidine kinase. However these markers are non-specific and can be...

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World Journal of Clinical Urology 2014年第3期3卷 272-282页

作者： Etsu Suzuki hiroaki Nishimatsu Yukio Homma Institute of Medical Science St. Marianna University School of MedicineMiyamae-kuKawasaki 216-8512 Japan The Department of Urology Faculty of Medicine University of TokyoBunkyo-kuTokyo 113-8655 Japan

Erectile dysfunction(ED)is an important health problem that has commonly been clinically treated using phosphodiesterase type 5 inhibitors(PDE5Is).However,PDE5Is are less effective when the structure of the cavernous body has been severely injured,and thus regeneration is *** cell therapy has been investigated as a possible means for regenerating the injured cavernous *** cells are classified into embryonic stem cells and adult stem cells(ASCs),and the intracavernous injection of ASCs has been explored as a therapy in animal ED *** marrowderived mesenchymal stem cells and adipose tissuederived stem cells are major sources of ASCs used for the treatment of ED,and accumulated evidence now suggests that ASCs are useful in the restoration of erectile function and the regeneration of the cavernous ***,the mechanisms by which ASCs recover erectile function remain *** studies indicated that ASCs were differentiated into the vascular endothelial cells,vascular smooth muscle cells,and nerve cells that originally resided in the cavernous body,whereas other studies have suggested that ASCs improved erectile function via the secretion of anti-apoptotic and/or proangiogenic cytokines ratherthan differentiation into other cell *** this paper,we reviewed the characteristics of stem cells used for the treatment of ED,and the possible mechanisms by which these cells exert their *** also discussed the problems to be solved before implementation in the clinical setting.

关键词： Erectile dysfunction Stem cell therapy Bone marrow-derived mesenchymal stem cells Adipose tissue-derived stem cells Endothelial progenitor cells Adrenomedullin Angiopoietin-1

Audio Watermarking Using Wavelet Transform and Genetic Algorithm for Realizing High Tolerance to MP3 Compression

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Journal of Information Security（信息安全） 2011年第3期

作者： Shinichi Murata Yasunari Yoshitomi hiroaki Ishii

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颈缘线处理中邻间隙龈中点线概念的引入

中国口腔医学继续教育杂志 2010年第6期13卷 37-50页

作者： Takeshi Nozawa Shunzo Tsurumaki Satoshi Yamaguchi hiroaki Enomoto Koichi Lto 王宪娥（译）徐莉（审）不详北京大学口腔医学院牙周科北京海淀区中关村南大街22号100081

本文的第一个目的是研究上颌前牙区龈缘最低点与邻间隙龈中点（IGM）线的关系。在观察的77位病人模型上标记出牙颈缘最低点及近、远中邻间隙的龈中点后，在硅橡胶模型上测量出连接邻间隙龈中点的IGM线到颈缘最低点的最短距离。结果显示... 详细信息

本文的第一个目的是研究上颌前牙区龈缘最低点与邻间隙龈中点（IGM）线的关系。在观察的77位病人模型上标记出牙颈缘最低点及近、远中邻间隙的龈中点后，在硅橡胶模型上测量出连接邻间隙龈中点的IGM线到颈缘最低点的最短距离。结果显示上颌中切牙颈缘最低点的平均位置与IGM线一致。在上颌侧切牙，颈缘的最低点在IGM线腭侧0．24mm．而在尖牙则位于唇侧03mm。本研究的第二个目的是通过一些病例于颈缘线处理中．IGM线概念的引入。一位牙龈厚平生物型的患者．采用临床牙冠延长手术治疗，经过对牙龈冠向生长情况的长时间观察，发现颈缘最低点最终与IGM线接近。而对一个薄扇牙龈生物型的病例短期观察中，发现邻间隙牙龈增加后游离龈也会增加。在一个Miller I度牙龈退缩的病例中．基于IGM线的概念，进行了一个冠向复位瓣联合转瓣技术的手术。根据本研究及临床病例观察得到的结果，IGM线有可能成为牙周成形手术中颈缘线处理的参照标准。

关键词：颈缘线牙龈退缩上颌前牙区病例观察手术治疗 IGM 上颌侧切牙最短距离

A randomized controlled trial of lifestyle self-monitoring for irritable bowel syndrome in female nursing school students

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Open Journal of Gastroenterology 2013年第8期3卷 328-336页

作者： Yukiko Okami Gyozen Nin Kiyomi Harada Masayo Iwasa Kaori Kitaoka Ayako Saruwatari Wataru Aoi Sayori Wada Misaka Kimura hiroaki Asano Yusuke Okuyama Susumu Takakuwa Motoyori Kanazawa Shin Fukudo Tomiko Tsuji Akane Higashi Department of Behavioral Medicine Tohoku University Graduate School of Medicine Sendai Japan Department of Education Kyoto Women’s University Kyoto Japan Department of Gastroenterology Japan Red Cross Kyoto Daiichi Hospital Kyoto Japan Department of Health and Nutrition Nagoya Bunri University Inazawa Japan Department of Health and Nutrition Nagoya Bunri University Inazawa Japan Ex-Graduate School of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan Ex-Graduate School of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan Ex-Graduate School of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan Department of Health and Nutrition Kyoto Koka Women’s University Kyoto Japan Ex-Graduate School of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan School of Nursing Kyoto Prefectural University of Medicine Kyoto Japan Faculty of Bioenvironmental Science Kyoto Gakuen University Kameoka Japan Graduate School of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan School of Nursing Kyoto Prefectural University of Medicine Kyoto Japan

Background: The aim of this study was to verify the efficacy of lifestyle self-monitoring for the improvement of the IBS and reveal what has been changed due to the intervention. Methods: A total of 111 nursing school students were randomized into three groups, two intervention groups (a two-month intervention group, n = 34, and a four-month intervention group, n = 35) and a control group (n = 34). The intervention groups conducted lifestyle self-monitoring in conjunction with a 15-minutes group work for either two or four months. The primary outcome measure was Rome II criteria for IBS. Other outcome measures were the Hospital Anxiety and Depression Scale (HADS) and the Gastrointestinal Symptom Rating Scale (GSRS). They were assessed at the baseline and the end of both of the intervention periods. Analysis was conducted as intention-to-treat. Results: The prevalence of IBS did not change significantly after the intervention in any of the groups. The HAD-A score, a subscale of the HADS score for anxiety, decreased 1.4 points in the two-month intervention group (p = 0.02) and 2.3 points in the four-month intervention group of (p = 0.01) after intervention. The average GSRS decreased 0.2 points in the control group (p = 0.05) and 0.3 points in the four-month intervention group (p < 0.01). Conclusions: Lifestyle self-monitoring for two or four months did not reduce the prevalence of the IBS significantly, but it did decrease anxiety and improved the QOL related to gastrointestinal symptoms in female nursing school students.

关键词： Lifestyle Self-Monitoring Irritable Bowel Syndrome Hospital Anxiety and Depression Scale Gastrointestinal Symptom Rating Scale Nursing School

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“北京主义”的实验地

现代装饰 2008年第1期 68-75页

作者： Yoko FUJII hiroaki SAWAMURA Bo XU Misae Hiromatsu（摄影） Keiichiro Sako（迫庆一郎）（设计） Yoko Fujii（设计）不详 Beijing NDC Studio Inc.

设计师广场项目位于北京市丰台区看丹桥西南角，占地面积17949平方米，总建筑面积99206平方米，由4栋23或26层高层塔式酒店公寓及大型综合商业组成。

关键词：北京市实验主义占地面积建筑面积设计师型综合平方

Effect of Universal Primers on the Tensile Bond Strength between Zirconia and Resin Composites

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材料科学与工程（中英文B版） 2021年第1期11卷 1-7页

作者： Akinori Ohno Mizuki Nagata hiroaki Kobayashi hiroaki Yamaguchi Katsura Ohashi Kaori Aoki Tomotaro Nihei Katsuhiko Kimoto Department of Oral Interdisciplinary Medicine Prosthodontics&Oral Implantology Graduate School of DentistryKanagawa Dental University82 Inaoka-choYokosukaKanagawa 238-8580Japan Division of Clinical Biomaterials Department of Oral ScienceGraduate School of DentistryKanagawa Dental University82 Inaoka-choYokosukaKanagawa 238-8580Japan

This study aimed to evaluate the effects of universal primers on the tensile bond strength between zirconia and resin *** specimens were divided into five groups based on the surface treatment with the following primers:MP(Monobond Plus),SU(ScotchBond Universal),AZ(AZ Primer),BM(Beauty bond Multi),and BL(Bondmer Lightless).After priming,stainless steel rods were bonded to the zirconia specimens with composite *** tensile bond strength test was performed:stored at room temperature for 1 day;stored in distilled water at 37°C for 7 days;and underwent thermal *** BL group demonstrated a significantly higher tensile bond strength than other groups when stored at room temperature for 1 day(p<0.05).The primer that acted via chemical polymerization appeared to be most effective in improving the bond strength between the two materials in this study.

关键词： Universal primer zirconia composite resin bond strength.

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澳门地区丙型肝炎病毒基因型分析

中华实验和临床病毒学杂志 1995年第3期9卷 202-205页

作者：王宇何绍滔冈本宏明北京医科大学人民医院肝病研究所澳门镜湖医院检验科日本自治医科大学预防生态研究室

应用逆转录－ＤＮＡ聚合酶链反应（ＲＴ－ＰＣＲ）及ＤＮＡ序列分析，对采自澳门地区的４３例抗－丙型肝炎病毒（ＨＣＶ）抗体阳性的慢性肝炎患者及５５例血液透析患者血清进行了ＨＣＶＲＮＡ检测及基因型分析。结果显示，１５例慢性肝... 详细信息

应用逆转录－ＤＮＡ聚合酶链反应（ＲＴ－ＰＣＲ）及ＤＮＡ序列分析，对采自澳门地区的４３例抗－丙型肝炎病毒（ＨＣＶ）抗体阳性的慢性肝炎患者及５５例血液透析患者血清进行了ＨＣＶＲＮＡ检测及基因型分析。结果显示，１５例慢性肝炎患者中，８例为Ⅱ／１ｂ基因型，７例为６ａ型。在１１例ＨＣＶＲＮＡ阳性的血液透析患者中，１例为Ⅰ／１ａ型，５例为Ⅱ／１ｂ型，１例为６ａ型。这种基因型分布与在中国内地城市所得结果明显不同，提示丙型肝炎病毒在中国内地及相邻地区的广泛传播可能仅是近半个多世纪的事件。

关键词：丙型肝炎病毒基因型分析

Implementation of an educational program for pancreaticoduodenectomy in a university hospital: a retrospective observational study

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Journal of Pancreatology 2021年第2期4卷 99-105页

作者： Sohei Satoi Tomohisa Yamamoto So Yamaki Satoshi Hirooka Daisuke Hashimoto Tatsuma Sakaguchi Hironori Ryota Rintaro Yui Kazuto Sakuramoto Hideyuki Matsushima hiroaki Yanagimoto Hideyoshi Toyokawa Taku Michiura Kentaro Inoue Mitsugu Sekimoto Department of Surgery Kansai Medical UniversityOsakaJapan

Objective:No ideal training system exists for pancreaticoduodenectomy(PD).We developed an educational system that uses an objective structured assessment of technical ***:This retrospective observational study was conducted using the data of consecutive trainees and patients who underwent PD from 2007 to 2013 in Kansai Medical University *** total score on the task checklist(21 parameters)for measuring technical performance during PD by self assessment and instructor assessment was compared between junior(JN)and hepatobiliary pancreatic(HBP)trainees at a university *** outcomes of 303 PDs(2007-2013)were also compared among JN trainees,HBP trainees,and instructors,and the present position of the trainees was *** study was approved by the institutional review board of Kansai Medical University on May 26,***:The self-assessment score on the task checklist was significantly higher for the HBP trainees than for the JN trainees on all parts of PD(P<.001).The discrepancy between self-assessment and instructor assessment improved in 3 JN trainees after experience with the first 5 *** total score curves rose to the right in the JN group,scores in the HBP group were stable,at 70 or higher,which correlated with the instructor *** 90-day and 30-day mortality rates were 1.6%and 0.3%,*** and morbidity after PD did not differ between the JN and HBP trainees or between the instructors and the *** of 10 trainees became board-certified expert surgeons of the Japanese Society of Hepatobiliary Pancreatic ***:These results indicated good construct validity of the task checklist *** program was safely and effectively implemented in terms of surgical outcomes and final outcomes of trainees becoming board-certified expert surgeons.

关键词： Educational program Morbidity Mortality OSATS Pancreaticoduodenectomy