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purinergic signaling systems across comparative models of spinal cord injury

Neural Regeneration Research 2022年第3期17卷 2391-2398页

作者： eva e.Stefanova Angela L.Scott Department of pathology and Molecular Medicine McMaster UniversityHamiltonONCanada

Within the last several decades,the scientific community has made substantial progress in elucidating the complex pathophysiology underlying spinal cord ***,despite the many advances using conventional mammalian models,both cellular and axonal regeneration following spinal cord injury have remained out of *** this sense,turning to non-mammalian,regenerative species presents a unique opportunity to identify pro-regenerative cues and chara cterize a spinal cord microenvironment permissive to *** the signaling pathways hypothesized to be dysregulated during spinal cord injury is the purinergic signaling *** addition to its well-known role as energy currency in cells,ATp and its metabolites are small molecule neurotransmitte rs that mediate many diverse cellular processes within the central nervous *** our unde rstanding of the roles of the purinergic system following spinal cord injury is limited,this signaling pathway has been implicated in all injury-induced secondary processes,including cellular death,inflammation,reactive gliosis,and neural *** that the purinergic system is also evolutionarily conserved between mammalian and non-mammalian species,comparisons of these roles may provide important insights into conditions responsible for recovery ***,we compare the secondary processes between key model species and the influence of purinergic signaling in each *** our understanding of this signaling system and pro-regenerative conditions continues to evolve,so does the potential for the development of novel therapeutic interventions for spinal cord injury.

关键词： cell death differenriation glia inflammation neurogenesis proliferation purinergic signaling reactive gliosis regeneration spinal cord injury teleost

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Rapid Descriptive Consumer Analysis Using Simultaneous and Monadic Sample presentation for Coffee

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Food and Nutrition Sciences 2018年第2期9卷 63-76页

作者： Chloe N. Stokes Joseph p. Kerry Maurice G. o’Sullivan The Food packaging Group School of Food and Nutritional Sciences University College Cork Cork Ireland

The objective of this study was to investigate how rapid descriptive consumer analysis using simultaneous presentation of samples compared with monadic presentation of samples, using both affective and descriptive sensory evaluation methods. Simultaneous presentation of coffee samples for sensory acceptance testing, using ranking analysis, was conducted using na?ve assessors. In a separate session, assessors evaluated the same coffee samples, using monadic presentation and employing the same scales. Similarly, descriptive consumer analysis, using simultaneous and monadic sample presentation, was conducted using descriptive attributes chosen by the panel. For RDA (Ranking descriptive analysis), coffee samples were presented simultaneously (randomised) to assessors and subsequently ranked. The process was then repeated using the same assessors;however, samples were presented in monadic and randomised presentation order. Data accumulated from the study were analysed by Analysis of Variance (ApLSR-ANoVA partial Least Squares Regression). Results obtained indicate that simultaneous presentation of samples was more effective than monadic presentation, as a larger amount of attributes with significant (p ensity differences were observed using RDA. Thus, simultaneous presentation of samples also allows ranking in SAT evaluation and proved a useful tool in establishing the hedonic attributes of products. We propose to call this method Ranking Acceptance Analysis (RAA).

关键词： Sensory Hedonic Descriptive Ranking Coffee

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Multispecies communities:interspecies interactions influence growth on saliva as sole nutritional source

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International Journal of oral Science 2011年第2期3卷 49-54页

作者： paul e.Kolenbrander National Institute of Dental and Craniofacial Research National Institutes of Health

Human oral bacteria live in multispecies communities in the biofilm called dental plaque. This review focuses on the interactions of seven species and the ability of each species individually and together with other species to grow on saliva as the sole source of nutrient. Community formation in biofihns in flow cells is monitored using species-specific fluorophore-conjugated immunoglobulin Gy and images are captured by confocal microscopy. early colonizing veillonellae emerge from this review of interspecies interactions in saliva as a critical genus that guides the development of multispecies communities. Highly selective interspecies recognition is evident as initial colonizers pair with early and middle colonizers to form multispecies communities that grow on saliva.

关键词： growth on saliva multispecies communities biofilm flow cell interspecies interactions

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Grain boundary effect on structural, optical, and electrical properties of sol-gel synthesized Fe-doped Sno_(2) nanoparticles

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Chinese physics B 2021年第4期30卷 555-564页

作者： Archana V Lakshmi Mohan Kathirvel p Saravanakumar S Department of Sciences Amrita School of EngineeringCoimbatoreAmrita Vishwa VidyapeethamIndia Research and Development Center Bharathiar UniversityCoimbatore-641046TamilnaduIndia GRD Center for Materials Research Department of PhysicsP S G College of TechnologyCoimbatore-641004TamilnaduIndia Department of physics N S S CollegePandalam-689501KeralaIndia

Tin oxide(Sno_(2)) and iron-doped tin oxide(Sn_(1-x)Fe_(x)o_(2),x=0.05 wt%,0.10 wt%) nanoparticles are synthesized by the simple sol-gel *** structural characterization using x-ray diffraction(XRD) confirms tetragonal rutile phases of the *** variations in lattice parameters and relative intensity with Fe-doping concentration validate the incorporation of iron into the *** compressive strain present in the lattice estimated by using peak profile analysis through using Williamson-Hall plot also exhibits the influence of grain boundary formation in the *** radiative recombination and quenching observed in optical characterization by using photoluminescence spectrum(pL) and the shift in the band gap estimated from UV-visible diffused reflectance spectrum corroborate the grain boundary *** spectrum and the morphological analysis by using a field emission scanning electron microscope(FeSeM) also indicate the formation of grain *** compositional analysis by using energy dispersive x-ray spectrum(eDAX) confirms Fe in the Sno_(2) *** conductivity studies exhibit that the impendence increases with doping concentration increasing and the loss factor decreases at high frequencies with doping concentration increasing,which makes the Sn_(1-x)Fe_(x)o_(2) a potential candidate for device applications.

关键词： sol-gel compressive strain grain boundary AC conductivity

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Nonlinear interferometers with correlated photons:toward spectroscopy and imaging with quantum light

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Light(Science & Applications) 2020年第1期9卷 840-841页

作者： Konstantin e.Dorfman State Key Laboratory of precision Spectroscopy East China Normal UniversityShanghai 200241China

A nonlinear optical interferometer based on crystal superlattices has been demonstrated for the first time in a cascade of up to five *** enhanced sensitivity due to quantum interference and correlations makes it a pr... 详细信息

关键词： spectroscopy quantum Nonlinear

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用静电模壁润滑—温压复合工艺增高粉末冶金零件生坯与烧结件性能

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粉末冶金技术 2006年第3期24卷 227-232页

作者： p.Lemieux Y.Thomas p.e.Mongeon S.pelletier S.St-Laurent 郭瑞金韩凤麟（译） Industrial Materials Institute National Research Council 75 de MortagneBouchervilleQuebecCanada J4B 6Y4 Quebec Metal powders Limited 1655 Marie VictorinSorel-TracyQuebec J3R 4R4 不详

对于生产静态与动态力学性能高的粉末冶金零件,在合理价格下,使零件材料达到高密度,有一定效益。采用温压—模壁润滑复合工艺是增高粉末冶金零件材料密度的一条很受人关注的途径。在试验室条件下进行的一些研究证实了这条工艺路线的潜... 详细信息

对于生产静态与动态力学性能高的粉末冶金零件,在合理价格下,使零件材料达到高密度,有一定效益。采用温压—模壁润滑复合工艺是增高粉末冶金零件材料密度的一条很受人关注的途径。在试验室条件下进行的一些研究证实了这条工艺路线的潜力。在工业生产条件下,对于这种复合工艺的实际效益需要进一步探索。为确定这种复合工艺使材料达到较高密度,从而达到较高的力学性能方面能达到何种程度,在工业生产用机械式压机上进行了试验研究。这篇论文对这种复合工艺和常规的冷压与温压工艺,以及冷压—模壁润滑复合工艺的效益进行了比较与评估。

关键词：温压静电模壁润滑粉末冶金零件

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Antifouling Technology Trends in Marine environmental protection

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Journal of Bionic engineering 2021年第2期18卷 239-263页

作者： Limei Tian Yue Yin Wei Bing e Jin Key Laboratory of Bionic engineering Ministry of EducationJilin UniversityChangchun 130022China Weihai Institute for Bionics-Jilin University Weihai 264207China School of Chemistry and Life Science Changchun University of TechnologyChangchun 130012China

Marine fouling is a worldwide problem,which is harmful to the global marine ecological environment and economic *** traditional antifouling strategy usually uses toxic antifouling agents,which gradually exposes a serious environmental ***,green,long-term,broad-spectrum and eco-friendly antifouling technologies have been the main target of engineers and *** recent years,many eco-friendly antifouling technologies with broad application prospects have been developed based on the low toxicity and non-toxicity antifouling agents and *** this review,contemporary eco-friendly antifouling technologies and materials are summarized into bionic antifouling and non-bionic antifouling strategies(2000-2020).Non-bionic antifouling technologies mainly include protein resistant polymers,antifoulant releasing coatings,foul release coatings,conductive antifouling coatings and photodynamic antifouling *** antifouling technologies mainly include the simulated shark skin,whale skin,dolphin skin,coral tentacles,lotus leaves and other biology *** future research directions and challenges are also discussed in the end,and we expect that this review would boost the development of marine antifouling technologies.

关键词： biofouling antifouling technologies bionic non-bionic biofilm

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Sub-stand diameter distribution types vary along an old-growth Douglas-fir chronosequence into the horizontal diversification development stage

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Journal of Forestry Research 2023年第2期34卷 415-424页

作者： JeriLynn e.peck eric K.Zenner Department of ecosystem Science and Management The Pennsylvania State UniversityUniversity ParkPA 16802USA

Managing mature Douglas-fir[pseudotsuga menziesii(Mirb.)Franco]stands to emulate the structural complexity of natural old-growth forest requires identifying structural targets at the sub-stand level at which neighborhood dynamics and patchy disturbance shape *** therefore sought to describe the archetypal shapes of predominant sub-stand diameter distribution types(DDTs)observed in natural tree neighborhoods in stands comprising a chronosequence(ca.120-450+yrs)encompassing mature,vertical diversification,and horizontal diversification development *** ten 1.0 ha stands are located in the southcentral oregon Cascades,*** on the known spatial position of each tree,natural tree neighborhoods were identified using the floating neighborhood approach based on spatial tessellation connecting neighboring trees at the first-(mean 61 m2)through fifth-(mean 2058 m2)order *** analysis was then used to objectively identify the most predominant DDTs among the relative tree size distributions observed in the trans-scale neighborhoods within each *** measures regression was used to classify each DDT to one of six observed archetypal shapes:negative exponential,unimodal,rotated sigmoid,bimodal,concave,or *** three of the 81 observed DDTs deviated byom the stand average,while every stand had at least one DDT that deviated by>50%(maximum 83%).Within each stand,five to ten predominant DDTs were observed,which deviated from the stand average by 30-48%and were characterized by two to five different archetypal ***,in some stands the majority of tree neighborhoods were best characterized by a different shape from that assigned at the stand *** from the stand average increased from the youngest stand in the mature development stage through the middle stands in the vertical diversification stage to the oldest stands in the horizontal diversification *** complexity of DDT shapes tended to increas

关键词： Diameter distribution type Floating neighborhood Restoration silviculture Small-scale Structural complexity

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Velocity of Surface Ice Flow on Amery Ice Shelf Determined with ppp

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Geo-Spatial Information Science 2005年第4期8卷 251-256页

作者： ZHANG Xiaohong e Dongchen School of Geodesy and Geomatics Wuhan University 129 Luoyu Road Wuhan 430079 China 不详

The main activities in the joint expedition between CHINARe and ANARe on Amery ice shelf are introduced. Five day continuous GpS observation data collected on the site which locates at the frontal part of Amery ice shelf was processed with precise point positioning (ppp) technology based on precise products from IGS. Velocity of the surface ice flow on Amery can be derived from the ppp solution. preliminary result shows that the surface ice flow velocity of the site is 2.25 meters per day, the motion direction is northeastward. Semidiurnal oceanic tide and diurnal oceanic tide signal of that site can be recovered from the height variation series of ppp solution. These above solutions can be used to the consequent mass balance calculation.

关键词： GpS precise point positioning Amery ice shelf surface snow velocity

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Updates on the relation of weight excess and reproductive function in men： sleep apnea as a new area of interest

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Asian Journal of Andrology 2012年第1期14卷 77-81,176,177页

作者： Ahmad o Hammoud Douglas T Carrell Mark Gibson C Matthew peterson A Wayne Meikle Division of Reproductive endocrinology and Infertility Department of Obstetrics and Gynecology University of Utah School of Medicine Salt Lake City UT 84108 USA Androiogy and IVF Laboratories Department of Surgery （Urology） and Physiology University of Utah School of Medicine Salt Lake City UT 84108 USA endocrinology/ Diabetes Research Department of Medicine University of Utah School of Medicine Salt Lake City UT 84132 USA

obesity has a negative effect on male reproductive function. It is associated with low testosterone levels and alteration in gonadotropin secretion. Male obesity has been linked to reduced male fertility. Data regarding the relation of obesity to sperm parameters are conflicting in terms of the nature and magnitude of the effect. New areas of interest are emerging that can help explain the variation in study results, such as genetic polymorphism and sleep apnea. Sleep disorders have been linked to altered testosterone production and hypogonadism in men. It was also correlated to erectile dysfunction. The relation of sleep disorders to male fertility and sperm parameters remains to be investigated. Men with hypogonadism and infertility should be screened for sleep apnea. Treatment of obesity and sleep apnea improves testosterone levels and erectile function.

关键词： infertility male infertility reproductive function sleep apnea weight excess

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